Creating New Neurons: The Potential to Reverse Parkinson’s Disease
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- Опубліковано 19 чер 2024
- Hear directly from the team that developed the groundbreaking ability to make new, healthy neurons that can replace those lost in Parkinson’s disease and their vision to turn their discovery into a life-changing therapy. [Show ID: 37041]
00:00 - Titles
00:14 - James Brewer, MD, PhD
13:58 - Xiang-Dong Fu, PhD
27:59 - Don Cleveland, PhD
38:43 - William C. Mobley, MD
43:37 - Q&A
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More from: Innovations Shaping the Future of Parkinson's Disease Treatment
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This is amazing and then some, and I should be excited. Instead I'm heartbroken because of the time perspective. Parkinson's is destroying my 79-year-old dad NOW, and it's been progressing horrifyingly fast. He'll be moving to a nursing home soon.
So instead of rejoicing, I find myself wishing that the scientists would throw most of their caution to the wind and start human trials immediately, risk of side effects be damned. I wish they would leave the question of how lasting the effect would be for later. I don't care whether the new neurons would be susceptible to the same degeneration as the old ones; just make new ones and deal with that problem later if it comes. PLEASE! ... You know? That "We need to know" list drove me crazy.
I'm sorry. I know I'm being an a**hole about this. I'm just so desperate and afraid, about to burst with grief. I can think about nothing else, only my dad's suffering. The powerlessness - his and mine and my sisters' - is unbearable. The emotional pain is constant and devastating. We need help now.
So it Goes--incurable, idiopathic, and always progressing. So iT gOES BE WELL
redlightsonthebrain blog
We have 6,000 worldwide members. No fee.
"Parkinson's disease relief”
@@abasicservice1com how to join?
Please look into PDCare laser treatment to stop degeneration until cure is developed.
I am very excited of these breaking therapy. I am also a care giver for my partner her development of Parkinson's is increasing daily. Help can only come asap. Thank you all for your work! The future population can now have some hope.
This was 2021 - now, a year later, when could we think of human trials and how would one apply to be a part of any human trials UC is planning? How can one contact the people involved with this really fantastic and amazing discovery? You ask what can now be done and that IS the question and how can a person with early Parkinson's be a part of it?
A year ago I was diagnosed with dementia, now it's been updated to possibly Parkinson. I knew ten years ago something was wrong, as my fine motor, fingers was getting hard to manipulate small things. Today I have multiple symptoms that in my mind say's I have it.
Good Job, please do it as fast as you can. A lot of people waiting.
How long have you been suffering from Parkinson’s disease ?
Such a great information thanks for sharing! ❤️ from 🇺🇸
Thank you for helping people
What can we do to help speed things up? Is it a funding issue, or sequential research issue?
I really hope everything turns out a success!🙏🏼 This was a miraculous discovery! Good job team!👍🏼👍🏼 In all that was discussed. I was wondering. Is anyone working on. Or discovered yet. How to recreate beta cells in Type 1 Diabetics? This discussion makes me think this can be done!🤔
Thank you for bringing hope.
i guess it's pretty off topic but does anyone know of a good website to stream new movies online?
@Walter Lucca Lately I have been using flixzone. Just google for it :)
@Bowie Malachi yea, have been using flixzone for since april myself :D
@Bowie Malachi thank you, I went there and it seems like a nice service =) Appreciate it !
@Walter Lucca Happy to help =)
Rapper with Parkinson's disease here. Newly diagnosed. I will never stop though.
Great discussion and news. PTB is a gatekeeper for regeneration and can be managed. Let’s hope so.Thank🍁you for your perseverance in pursuit of a cure for PD. And, Thank🍁you Sergy Brin.
Doc I quit. My meds and want to have your opinion on clorine dioxide.for a potential drug for parkinson 0
Can you tell ne how to get emidiate theropy
Amazing 🤩
So curious to see so much enthusiasm so early. Niave on my part? We should be patient right?
I’m 32 and at 21, I was diagnosed with a VERY, VERY, VERY rare genetic condition called Friedrich’s Ataxia. Unfortunately it’s progressive. Essentially my body can’t produce frataxin anymore which causes many symptoms like neuropathy, lack of muscle coordination, etc. and increases the risk of heart disease and diabetes. As far as I know, there is not a lot of knowledge on what frataxin’s actually roll is but it’s involved in iron-sulfur clusters in mitochondria, what ever that means lol.
Now fortunately for me my condition is progressing a lot slower then others who have this condition but this does not mitigate my future outcome. It has taken running, hockey, motorcycles, skiing/snowboarding and many others. Even other activities/hobbies that Ive never done and would love to try. On top of that it’s made it extremely difficult to go out and even enjoy simpler things like traveling, concerts etc. let’s just say everything that involves both your legs and balance simultaneously. I still walk (w/ a walking stick mostly), I still drive (even a stick), I still work and I still play guitar. Walking seems to be the only activity, right now, that I feel I’m holding on to by a thread, I feel it’s really only my lack of balance. Is really my biggest issue at this point. Guitar is really the only hobby and talent that I have left. If I loose that then there is not really anything for me to live for anymore since I’m single and don’t have children. I’m trying to hold on to that best I can.
Holy crap I’m sorry this comment turned into a book. It was intended to be only a paragraph lol. If you read this entire rant thank you and ✋ to you! That being said, the only thing I wanted to say is this video seems very exciting and in my opinion and shows more promise than the CRISPR case9 stuff. Now CRISPR, from a medical context, looks great for near future applications but at the same time it makes me real nervous. I feel like it’s like watching a child run through a field of tall dry grass and tinder with a torch. Not sure if this is the best analogy lol. It’s the only one I can think of at the moment haha! In short I’m about 30/70 for it right now.
@@tomhennessy7276 do you know more about FA? Im just very curious if your a doctor of some sort.
@@tomhennessy7276 Are you a neurologist? Have you heard about Omaveloxolone?Supposably it is FDA approved now for a treatment for FA but I’m not sure. It apparently had very positive results during the clinical trials with minimal side effects. I may be interested in trying but I want more info before I try it out.
@@tomhennessy7276 Thank you for the info. I read the vitamin E in mice study. I will try supplementing with vitamin E and see if it helps. Have you heard anything about diet helping?
@@tomhennessy7276 I’m a big believer in getting vitamins with food. I would eat more foods w/ vitamin E and supplement a little with for a bit and see if I felt a slight change. I definitely wont be stupid and go crazy with it.
I know a company called Clearpoint neuro that is supporting clinical trials involved in the treatment of freidreichs ataxia. Give it some research 👍
I have a brother with Parkinson's. We are so desperate to get him help. His only 48. Is there a clinic that I can take him to get treated.
Hi my name is raffi I've got essential tremors and I would like to know more about your treatment and medicine that might be able to help my tremors.
bless the animals that w/o volunteering, give out their lives to advance research aimed to humans.
we do little to honor them.
wish the best for this project.
Amen
They're not really volunteering though
13 to 15 year development? We can create covid vaccine in one year and approve in a month but millions of people have wait over a decade for such treatment? It shows how little medicine has changed past 50 years
It's all about the money just like NASA look what Elon Musk did in 6 years that NASA didnt do in 60.
Ummm yes there is a major difference between a virus and an auto-disease that someone’s body just does.
Vaccine didn’t work for “Covid”
Yea, look how that worked out 🙄.
I would prefer to have slower development of any type of intervention that attempts to change rna . Otherwise we may have results like the ones we had with the COVID "vaccines". Vaccine is supposed to PREVENT a virus, not just make it milder. I'm not even convinced that it did that actually. When we have the hubris to think we can change outcomes of our messing around with nature, we make things worse ... and then refuse to admit or accept that we did so.
Are glial cells. To nerons more common and easier to convert into nerons because of recent discovery than plirie potent cells
So heartbreaking to realize that by the time this gets approval...if ever ( I don't trust the drug companies to get behind it and actually market it and they control way too much) my husband who was diagnosed with PD 7 years ago and is already 5th stage of PDD, will probably be gone but not before his care has bankrupted us.
Bu hastalar çok zor durumda neden ilaç bu kadar geçikiyor ne olur hızhandır
I love this
I have a friend in Colombia who was just diagnosed - he studied here in the US in college with me years ago and we were good friends and recently began communicating - how can we contact you so he can participate in the study ? I am about 7:45 min Now , I will continue to watch
We have 6,000 worldwide members. No fee.
"Parkinson's disease relief”
I'm curious what your collective take might be on Sage Therapeutics and zuranolone?
What happens, tell me if there is an improvement I beg you🙏
This could also lead to a breakthrough in issues of the visual cortex where neurons are lacking, such as Amblyopia.
Amazing breakthrough. My Dad is 67 years old 10+ years suffering from this disease. The thing is Tidomet 25/250mg becoming so ineffective for him and I dont know what to do because other meds so expensive here in Phils.
Buy from India
What is his gut health like? Healthy gut means healthy brain, I would start there. Get him on good probiotics, magnesium, Q10, eliminate gluten and dairy, and see if there’s improvement
@@kathypr1051 These past few days it's getting harder, it's hard for him to eat and he doesn't like taking tidomet and rivotril anymore. He's having hallucination or saying something out of nowhere or nonsense, He can't get up from bed alone, He can't stand even within using his 4 legs Cane, His Dr. can't check him up because my Dad got this cough 4 weeks ago. I understand that the Dr. won't check him up due to covid. but I knew my dad don't have it and he got his vaccine as well. We don't know who to go from.
@@byuuubz can you change doctors? Sounds like he needs new meds. My mom is on carbidopa/levodopa and Amantadine, and she is stable.
curious have you tried photobiomodulation?
I'm in San Diego can I be part of these trials my neurologist is from ucsd
Repost this with visual diagrams of what are you talking about please
i hsve receny been diagnoist with parktnsons im 65 april 1 1958 is my birthday onhorably discharged cbs was my mos with 3 children and devored heard through y6outube that there might be a drug trial on turni ng gleial cells into neurons and want to get into a drug trial for This and looking to get a sugestion on this
If this actually goes somewhere, get this information to Michael J Fox. plus the rest of the community with it.
My mother had PSP a Parkinsonian type of disease she died last December, unfortunately after she. Had called covid recovered.. bug one day felt not good with vomiting.. after going to hospital the hospital killed her
Too long to wait for this😢
I got damaged by psychiatry in late 2006 as a comedy of errors. 30 grams of Lithium and Risperdal M-Tab cause Drug Induced Parkinson's. I got a social worker to pass me a note about the medication I was put on.
How!
Think I would like to participate in testing something for this neuropathic mess I'm encountering..t9t10 spinal mess from defective hf10 Nevro device. Or surgery moving it. Sting is unreal yet I'm trying to beat it..walk..and be normal..was paralyzed right leg n side..its a living hell each day..
Have you tried Alpha Lipoic Acid? Hyperbaric Oxygen Therapy?
@@theancientsancients1769 EXERCISE IS GOOD CENTRU VITAMINS
When can we began to get to this
What about Atypical Depression, thought by some to be caused by down-regulated dopamine in the HPA axis?
Hello
@@stivemichel8021 < uh.. well hello to you too …
Can Parkinson's is curable naw in India
Mom had Parkinson's, and I wonder if I am at risk to develop it myself???
This therapy can use for hemmorage
WHATS THE NAME OF THE DRUG I KEEP MISSING IT??
Alert us when you're seeking human trials. Our group contains 6000+ Parkinson's persons.
I hope it works
I think it's surprising that not much has changed regarding Parkinsons medication over the last 20 years.
Once you get used to taking them they become less effective.
I am watching my friend disappear as the months go by. Its frustrating that there dosent seem to be much progress.
We have 6,000 worldwide members. No fee.
"Parkinson's disease relief”
@@abasicservice1com WTF does this mean?
@@abasicservice1com how do I find this organization?
If you follow the conventional treatment, don’t expect any positive results other than going downhill. I refuse to believe in the medical establishment , you are better off if you are seeking a cure from people with success stories.
Sir what is PTB fulform
I got parkinson now ill be 65 april.1 my syptons are getting harder to deal with quickly i have 3 children and devorced question what do you know about turning glieal cells of the brain into neurons human trials i was into cbs in my 4yr honorably dis charged duty at a young age 17 yrs Are glial cells. To nerons more common and easier to convert into nerons because of recent discovery
A 72 veteran was diagnosed with PD. He had blacked out many times over the past 5 years. He had the tremors and slow muscle movement. He is taking the 2 prescribed medications. But then he started taking alpha gpc and lipasomal vitamin C daily. After a week or so he is moving like he did when he was 40!! I l know this could just be a miracle but I think these supplements made the biggest difference. His mind is on point. Razor sharp focus and recall. He is a preacher. He had to stop preaching because he had the bad tremors and couldn't recite the scripture he had inside his mind. But now he's back in the pulpit running around like a young preacher. It's been 3 months and he's still saying the PD is over!
I'm thinking the alpha gpc fixed a choline deficiency..who knows??
I am 54 with Parkinsons disease I was diagnosed at 46 and its getting so hard that I don't know how much longer I can go on 😢
curious have you tried photobiomodulation ?
We have 6,000 worldwide members. No fee.
"Parkinson's disease relief”
Watch Dr Berg Parkinson’s disease you tube
My partner just got a diagnosis: Morbus Parkinson. We live in Berlin. Is there a possibility to contact your institut and get help?
Warp Speed it! Or is it not as important as covid?
$&&&&&$$$&&&$$
What? Do you even state what the treatment is?
We have 6,000 worldwide members. No fee.
"Parkinson's disease relief”
I want to be apart of this I was diagnose and need help
curious have you tried photobiomodulation?
We have 6,000 worldwide members. No fee.
"Parkinson's disease relief”
I feel young from all the exercise that I did when I didn't have before 65yrs old is there hope for me not Richmond o poor side
Wait a minute - how do we know the new neurons will not be the evil neurons? I don't want to become my own evil clone.
I am a 64 year old female with Parkinson’s. Would love any help you could give me
curious have you tried photobiomodulation? Respect.
@@theweekendmurders4958 wr
We have 6,000 worldwide members. No fee.
"Parkinson's disease relief”
@@theweekendmurders4958 yes no change .....
2 yil gecti bunun yüzerinden, hala ilaç yokmu parkinson hastalıgı çok götü ne olur insanlar çok acı çekiyor, Allah rızası için hızlı olun.
Hi. Please, let us pray together. Dear God who art in heaven hallow be thy name thy kingdom come thy will be done on earth as it is in heaven, give us this day our daily bread and forgive us our trespasses as we forgive those who trespass against us and lead us not into temptation but deliver us from evil for thine is the kingdom and the power and the glory forever in Jesus Christ's name we pray amen.
You are going to the right place for sure DESTROY PARKINSON
HURRY UP.GUYS GOOD LUCK
You are going to make it for.sure god bless you
Pablo from argentina!
Hello sir,,,my mother is suffering from Parkinson,,,her condition deteriorating day by day,,,,she is now 56,,,,i don't know what to do,,,,,i need your help sir,,,pls suggest me🙏🙏🙏🙏🙏🙏
Deep brain stimulation. Not a cure, but will help tremendously with quality of life.
Me from India. Same problem to my mother .she is suffering from 9 years. Can u suggest Gd hospital in India
@@koteshkumar7018 find a hospital that does deep brain stimulation. It is likely to help with her tremor.
@@dakotastwits sir.. Deep brain stimulation work for 5to 10 years as per my knowledge and that too we are disturbing patient with surgery
@@koteshkumar7018 it helps with tremor and gait issues. Consult a neurologist/surgeon that performs it in your country.
People need help now! Start trials now! My mother is fading away because of this stupid disease!
Ill recommend you get psychedelic treatment from this mate online..
Mycodree
Hes on telegram,
@@queenalberth2164 I don't know what that is?
Get telegram it's an app,then you search on the above name
Kooch nahi hu
No viruses please! Too risky..do better please by using DNA designer drug..ty
What happened to your hair? I thought you said your a doctor?
Unfortunately spell-check can't teach you English, laddie. Looking at pictures in Guns and Ammo can't either. It's a shame.
You are truly a pathetic bot to make that comment
What you sow is what you reap. You are going to go bald.
Health care sucks
Still very surprises how all my symptoms of Parkinson’s disease just went aware after undergoing *MADIDAHERBALCENTER* treatment, but I am very much happy because I don’t longer have them anymore for like 9 months now.
Pleaser send me something on it please 🙏
This in my opinion is fluff. Follow the money! If Fox Foundation can raise hundreds of millions and have nothing to show for it, something is wrong.
Help me please 🙏
Please let us know address of this center and share us more details of treatment you received during your stay starting to end so others can benefit from your experience.