How Keto Affects Your Brain
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- Опубліковано 1 гру 2022
- Ketogenic Metabolic Therapy (aka ketogenic diet) has profound effects not only on the body's metabolism but on brain function. Pioneering clinicians are using ketogenic interventions to treat mental disorders like bipolar disorder, schizophrenia, anxiety and depression.
Physicians and Neuroscientists explain how keto (aka ketogenic diet / nutritional ketosis) affects the brain. Learn how ketogenic metabolic therapy works to restore brain function, reducing or eliminating symptoms of mental illness.
“Ketosis changes our metabolic physiology, which changes our brain chemistry. It can balance the neurotransmitter systems in the brain, balance the energy levels in the brain, and reduce systemic inflammation, which reduces neuroinflammation.”
Dominic D’Agostino, PhD, research scientist at IHMC and Associate Professor at University of South Florida.
Scientists and Clinicians featured in this video:
Jong Rho, PhD - UCSD
www.rchsd.org/doctors/jong-rh...
Zoltan Sarnyai, PhD - James Cook University
research.jcu.edu.au/portfolio...
Twitter: @ZSarnyai
Ana Andreazza, PhD - University of Toronto
psychiatry.utoronto.ca/facult...
Twitter: @anacandreazza
Dominic D’Agostino, PhD - University of South Florida
health.usf.edu/medicine/mpp/f...
Twitter: @DominicDAgosti2
Georgia Ede, MD - Harvard-trained psychiatrist, Diagnosis:Diet
www.diagnosisdiet.com/about
Twitter: @GeorgiaEdeMD
Chris Palmer, MD - Harvard and McLean Hospital
www.chrispalmermd.com/
Twitter: @ChrisPalmerMD
This video was recorded at the first ever Metabolic Psychiatry roadmap retreat, hosted by Baszucki Group and the Milken Institute for Strategic Philanthropy in May, 2022 in Santa Barbara. The conference brought together physicians, neuroscientists, dieticians, entrepreneurs, venture capitalists and philanthropists to build community in the emerging field of Metabolic Psychiatry.
Learn more about metabolic psychiatry and meet the visionary Metabolic Mind Award Winners at tinyurl.com/Baszucki-Group
About us:
Metabolic Mind™ is a nonprofit initiative incubated by Baszucki Group. Our mission over time will be to provide resources and build community in metabolic psychiatry.
JOIN OUR MAILING LIST AT metabolicmind.org/
Other resources for Metabolic Psychiatry, metabolic neuroscience and ketogenic metabolic therapy for mental disorders:
Diagnosis Diet - www.diagnosisdiet.com/
New Study: Serious Mental Illness Improves on Ketogenic Diet -
www.psychologytoday.com/us/bl...
The Role of Ketogenic Metabolic Therapy on the Brain in Serious Mental Illness: A Review
www.ncbi.nlm.nih.gov/pmc/arti...
Chris Palmer MD - www.chrispalmermd.com/
Stanford Metabolic Psychiatry- metabolicpsychiatry.com/
What Is Metabolic Psychiatry? 5 Questions Answered by Dr. Shebani Sethi
med.stanford.edu/news/all-new...
Baszucki Group - baszuckigroup.com/our-work/me...
BipolarCast: Keto + Bipolar youtube channel, Hosted by Matt Baszucki and Iain Campbell, PhD
/ @bipolarcast1133
/ iaincampbellphd
Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
#MetabolicMind
#KetoForMentalHealth
#MetabolicPsychiatry
#BipolarTreatment
#MetabolicNeuroscience
#KetogenicMetabolicTherapy
#NutritionalKetosis
#MentalIllnessTreatment
#MentalHealthIsMetabolicHealth
My anxiety is just gone not 2 weeks in to keto. Gone. Just... Gone.
Are you still carrying on with the diet? if so are you still benefiting from it?
@@UsmaanHussain yes still on it and still benefitting. The next thing I did was quit coffee which helped hugely too. I don't really miss anything I gave up. I have zero vices left 🤣😅
@@niamhmckinney4027 That's good to hear 😄 I'm gonna give it a try and see how it goes 👍🏻
It's because you're not getting blood glucose spikes. It's got to be a good thing.
@@user-hp6ls8qy6d yep I love it! Still on it and feeling great. Adding the odd piece of fruit now but I figure if fruit is my "cheat" I'm doing OK!!
I'm on week 6 of keto and glad to say that my previous anxiety is almost completely gone. Recently watched the Andrew Huberman podcast with Chris Palmer which pointed me towards Chris's book Brain Energy and I am happy to say that I will be on a Ketogenic diet for the rest of my life now.
@@Mijn3023 You're talking about this video: ua-cam.com/video/VmlC8UYZDlY/v-deo.html. The solution is simple: tailor towards LCT's or MCT's depending on what works for your body...
@@Mijn3023Hope you're doing okay. keto helps stabilise/clean the mind
@@funky8nimation
Hi!
I am epileptic and taking Lamotrigine.
Right now trying to stay in Keto diet.
I have several questions:
-What is the difference between MCT oil and LCT? (I have use MCT oil, but Never heard of LCT)
-Can someone witt Epilepsy take NAC supplements??? I heard is good for the brain, Something with glutamine and "neurotransmisores".
Thanks!
(Sorry for my English l am from Puerto Rico)
I was on keto for 2 months. I broke some other habits started working out and started to study and read more. During studying I thought I was just motivated to learn and thought that was the reason I was able to understand and interpret things in my own definition. It had been so long that I’ve picked a book up so again I thought this was normal for me. One weekend, I decided to drink alcohol beverages and broke my keto. It was a Friday and went back to my routine on a Monday. I went back to where I left off studying. Quickly noticed I was having a hard time focusing on both what I’m reading and trying to understand what I’m reading. The flow on information was not flowing like it was when I was on keto. For me it definitely affects the speed and process to gather information and interpret myself. Had to go back 2-4 times to even grasp the a concept. Crazy how affects other people
Thanks for sharing your story. It is interesting how it can affect different people in different ways. That's one of the fascinating aspects I would like to see more studies on. More to come!
7 months in are you still having the same mental affect?
@@jordanblake8 I'd like an update as well...What do ya say, Pablo the Great?
So a bit of information. Alcohol according to Dr. Palmer, can disrupt the functions of the mitochondria, it may even make it work differently in cells, on another note it also affects how the microbiome uses ethanol as fuel which throws off your neurotransmitters, since the bacteria do affect your neurotransmitters and how much is released.
@@johnmartinsen963 for what reason would the enhanced mentality cease? when you are deep in keto, there's no doubts about it
I didn't know anything about the KETO diet except it was low in Carbos & High in fat! I thought I would give it a try for a month. WOW! What a difference! Especially in my knee joints! I can now move so much better, & I can think more clearly! Oh, by the way, I'm 61 yrs. young. Don't let yourself being older stop you!🎉
I was in keto for like 8 months and I was able to lose weight. Work hard. Sleep better and even make more money. I got back into carbs and my whole life fell apart in 3 months
Can u clarify. I was carnivore for 2 yrs and felt amazing . now eating a bit of carbs. I have extreme anxiety and depression with no self esteem... it's nuts.. and frustrating that I cannot enjoy regular delicious foods...
@@boatdoctors yea idk what it is but my mind off ketosis is slow and weak. I’m back on keto and feel great. Fasting definitely helps too
I started Keto about a week ago. It’s so strange…there were times I felt tired and exhausted but I had unbelievable mental clarity - it felt like I was always ALERT and present. It’s like I wanted to go sleep cause I was tired, but I couldn’t because my mind was so energized!!!!
Clarity....
Thats like coked up
I have started keto with minimal carb like 50g and 0g processed sugar. I can see the difference already esp in my brain. It feels calm and my mood is good and that really surprised me. My whole life i struggled with chronic anxiety and the many opportunities i missed because of that. Approaching 40 now, im so thankful to these docs and experts on youtube. All i ever wanted is to experience life just like everyone else without anxiety. Its so tough living with it.
Thank you for sharing your experience. We are so happy to hear you have found an approach that helps you!
Alcohol doesn’t kick you out of ketosis granted it’s not beer or sugary beverages. You can have rum and Diet Coke or vodka with sugar free lemonade. Only thing you can’t have is carbs which alcohol doesn’t have. Sure your body will use the alcohol instead of fat to burn but it doesn’t kick you out it just slows it down temporarily. Just don’t drink often and you’ll be ok 😃
Don't listen to Alex..you'll grow up and not need crutches like drugs and alcohol. 50g carbs may be too high to actually be in ketosis. Keto is not a diet, it is a metabolic state. People can be in ketosis (keto) eating vegan, omnivore and carnivore diets. Home blood testing for ketones is easy, affordable and very beneficial when you are getting started. It gives you motivation, just like stepping on a scale might motivate eating and exercise habits. Any updates on your progress after 7+ months?
@@johnmartinsen963 I'm no longer on keto, not because it's bad but my personal preference. I made some changes from what i learned from it though. When i was on Keto my BP was shooting up. This happens because as your body losses glycogen, it also loses H20, Potassium and electrolytes. So its important to do Keto the right way. I didnt know this initially. Then i started to go generous on greens for potassium, kept myself hydrated and added himalayan salt to my food. My BP came to ideal levels since then and stayed almost consistently. On keto, my focus, eyesight, energy levels improved. Not perfect but significant results. I can attest it's not placebo. Anxiety episodes still happened here and there but not as frequent. For the past 2 months I've been eating more complex carbs. I'm no longer on ketosis, but i feel im still enjoying the benefits that i achieved from keto diet. Important thing is, I have completely shut off processed sugar/meat and fast food. They are the real culprit. I do very minimal home workout and still lost 15kgs in the past 7months. Thanks to Keto and minimal carb diet.
@@johnmartinsen963 there are a few zero-carb beers out there. keep in mind when you are deep in keto, 2 beers would already have you flying ;)
One of the controversies of the agriculture revolution is we’d become less dependent on our symbiosis with nature. Hunting and gathering days were long gone. We controlled the situation with the upper hand and now had the luxury of 3 square meals. No surprise our brains are naturally able to handle energy efficiently in only increments spread out by large gaps of time.
You should study what happens to our voice on keto. I've never felt better and everything is perfect on keto, except my voice, which is very, very weak. I'm a singer and I can't sing anymore. I also noticed that almost everybody who's promoting keto has a raspy voice. I don't want to go back to my previous diet but I also need my voice. The thing is, I can't find any help at all with this issue. I see people complaining about the same thing I'm complaining, but they also couldn't find help. I see no other way but to go back to eating carbs and feeling like sh*t because my voice is my job. I feel so frustrated it's hard to put it into words. When I finally found something great in my life, it came with a horrible side effect that turns it into a nightmare. Story of my life.
Can’t wait for more science to come out on this. Current psychiatric drugs aren’t a great long term solution for a lot of people, not to mention some prescriptions that are over $1,000/month.
Powerful, thank you.
My mother is 75 and my father is 80. They both have joint pain and are tired a lot. I'm 42 years old. I told my parents I have so much energy since doing keto. My mom says to me, wait until you get our age and then tell me how you feel. I told them that age has nothing to do with it. I said it's all the carbs you're eating that are making you tired and causing inflammation. They don't want to believe it. I told my parents that I see people older than them exercising. My parents don't even eat any salt. They think salt is evil. They think red meat is bad for you, and eggs are bad, and full fat dairy is bad. My parents eat pasta, cereal, pizza, bread, potatoes, they think those are healthier than red meat and eggs. Well I can only take care of myself.
I'm 78 and 95% carnivore. I have no arthritis in spite of being a lifelong jogger (still). I ride a horse and trim her hooves. I train and exercise a young Labrador. I mowed lawn with a push mower and use small power tools for other yardwork. I am painting the inside of my house, including ceilings. Its not age - its diet and exercise!!.
@@judymiller5154 exactly. After my mom eats cereal and toast for breakfast, 2 hours later she's exhausted. Barley has energy to wash dishes.
@Seawave669 its really hard to break through the brainwashing! Maybe they will meet an older, vibrant person who can tell them it doesn't have to be like that. At church potlucks, I just wait till somebody asks about my life then says they wish they had half my energy. I reply nobody wants to do what I do to have it. If they are serious, they track me down later. I feel for you in your situation. God bless ❤️ 🙏 ❤️
شكرا
Amazing !!
Keto may be good for those who already experience stress and anxiety. But Keto can and often does give people bad anxiety and panic attacks, esp those who aren’t normally anxious.
Thanks for your comment. Here's a video we did wit Dr. Lori Calabrese documenting 3 case studies of resolving anxiety with a ketogenic intervention. It may be worth watching for a different perspective. ua-cam.com/video/EuFhJeOf2Jc/v-deo.html
Prolonged fasting achieves a significant amount of ketones to be produced from fat storage.
The only problem with this is that it demonises carbohydrates. Zero refined carbohydrates and a small amount of complex carbs are fine, as long as you work them off. I don't thin being in keto all the time is necessary or even desirable. Low carb is probably enough and all of us have a different tolerance for carbohydrates depending on age, genetics, etc.
I have PMDD so 3 weeks out of the month I feel much better. My generalised anxiety has gone. I'm more active and productive but the week I ovulate I'm still a mess and nothings changed. I had hoped it would cure it, like it has helped with my period pain but keto hasn't helped my PMDD. Yet. Still hoping it will. It's a vicious cycle and I'm so tired of it.
Started keto 3 weeks ago and saw a difference in my mood, menstrual cycle came on and knocked everything back to square one, while still eating a keto diet. Like you stated this process of trial and error is so frustrating…
@@allthingsjanee7192 being woman is so hard sometimes. I know some women who have never even had period pain let alone turned into a completely different person because of their hormones. It's so unfair on us. Hope you're ok. I'm losing weight that's the only positive whilst I feel like this. X
@@Themis33 SO HARD, the only thing that keep me going is my faith and hope. I’ve tried multiple supplements and vitamins and nothing helps me. I really thought keto was going to be the saving grace but oh well. I see a difference in my weight and stomach area so that’s a plus and I’m doing alright at this moment you know it take a few days to get back to your normal self after your cycle. I hope you’re doing okay as well🤍
Give the carnivore or lion diet a try.
I wish I had known about progesterone cream in my younger years. You are estrogen dominant.
Not according to Paul Saladino and Georgi Dinkov who think we should be eating sugar and fruit which wouldn’t have been available throughout much of human evolution. Wish we could all get on the same page and figure this out.
It can be confusing, can't it! I think a big part is understanding, what is the goal? Is it weight loss and body composition? Or is it treating a specific condition like bipolar, or type 2 diabetes? In my opinion, the diet which gives the best chance at improvement should be more "strict" keto when treating a specific condition and can be less "strict" for weight loss and body composition. I hope that concept helps.
Would it work for everyone though?
Ketosis doesn't have the same effect on everyone. For some, it is mild, and for some, it is incredibly dramatic. Hopefully, further research and clinical experience will help us better determine ahead of time who will experience the greatest benefit.
❤
The keto diet results in ketones in the brain because of consumption of large amounts of saturated fat and no sugar spikes. You can do the same thing on a vegan diet by eating large amounts of cocoanut oil and avoiding sugar and refined carbs. What's the difference?
Great point. There likely is no difference. We like to be very clear that ketosis is a physiologic state, not one diet. People can achieve ketosis with a vegan, vegetarian, Mediterranean, omnivore, or carnivore diet. As Metabolic Mind team member Hannah Warren demonstrates, vegetarian keto can be very effective for mental health!
I know keto affects my brain. I've tried it as a diet method, but it almost immediately triggered a manic episode. The episode stopped when I started eating carbs normally again because of hospitalization.
I believe ketogenic diets might help some people with certain mental disorders, just not mine.
Thanks for sharing your experience. That can be a concern when people start on a keto diet. That's why we emphasize doing this in conjunction with your treating physician so you can monitor for concerning changes. It's important to know what works or doesn't for you as an individual. Thanks again for sharing!
That's withdrawal symptom, ketosis won't happen in one day. It needs two or more weeks for the whole body to adapt. Suggest you study it further.
My son had increased energy and decreased sleep both times he went quickly into ketosis. We treated this with extra anti-psychotic for two days. Without that intervention, it might have continued into mania or hypomania. But he got through it in just a couple of days. He is now tapering off meds and has zero symptoms of bipolar illness, not a single one. We really need to study this in bipolar so that we can figure out whether a more gradual decrease of carbohydrates is advisable, as well as making sure people have meds on hand to treat insomnia/hypomania during the initial few weeks transitioning into ketosis. I'm sorry this happened to you!
An elevation in stress hormones are a response to carb restriction. If thyroid function is not optimal, keto can worsen the symptoms you're trying to improve.
@@erickminor that was not the case for our son. I think there’s something different going on here.
you have mental clarity but you have also high cortisol and your brain works slower cause atp.
We are very curious about "your brain works slower." Would you mind adding more? Also, is this personal experience or research findings? Thanks!
@@metabolicmind One possible reason for high cortisol can be low sodium. On keto you tend to excrete more electrolytes. Most people have the mindset that too much salt is bad for blood pressure whereas it is more likely due to low potassium. The standard & cheaper serum blood test is not a good indicator for potassium deficiency. Intracellular test a better indicator.
@@metabolicmindhi, does cortisol go up?
brain fog?