Small correction: At time point 7:10, I say that "In liver, muscle, and fat tissue, insulin binds to the insulin receptor on the surface of cells, and that causes a specific glucose transporting molecule called GLUT-4 to be transported to the cell membrane". This is not correct, because GLUT-4 doesn't play a major role in glucose transport in the liver (where it's other glucose transporters such as GLUT-2). In muscle and fat tissue it is GLUT-4, however, so that part is correct.
@@ataho2000 hahahahaha, you're joking right? If not, rule #1 of correcting people is to actually be correct. You got us though, I'm still laughing... 'mono' can't mean 'one', hahahahhahahahha.... nice mono, uh, I mean nice one.
@atoms.channel I don't know Greek but they told me that they use "ena" for one and "mono" for single. Care to teach Greek People how to speak Greek? I don't know what to call this, Ignorance, arrogance or .........
@@atoms.channel On second thoughts, my mistake. English people have the tendency to take words from foreign languages ad bastardize them to their harts content so you can use the word "mono" any way you want.
Very clear and understandable information. I am watching videos like this and try to manage my food and activities for better health. In about 8 months I lost 52 lbs and I maintained the new weight for tw years. Now after two years my Hba1c dropped to 5.2 and am really happy because I am no more a pre diabetic person. Eat twice a day and walk about 4 miles a day.
Congrats! That's great to hear. I really do believe in the power of taking responsibility to ones own health, rather than thinking about health care only as something that is done to us. Cheers Mario
I am 71 yrs old, very active, slim 5'10". T2 for 15 yrs. Never knew about IR. Had T2 hubs so very little extra calories like gravy, biscuits etc. He followed ADA diet so had normal carbs with lunch & dinner. Was a pharmacist, checked his blood 8 times a day, and diabetic for 63 yrs. Had limited activities therefore, he had every complication. I can not do this to my family. My a1c always 7.3 & 7.5 and I must get into 6's. CGM last year & I love it. My numbers spike with many meals and trying to fast more. Always eat 1/2 restaurant meal. I am emptying my garage and doing way too much lifting, painting, cleaning, moving fridges and I just lifted 5 drawer tool chest. I just do not expect good numbers anymore. I joined hiking club and never walking on level ground. Loved it. I am desperate to save my organs. On 5 glucose meds & Toujeo insulin. Just sharing as there is something I am missing. I will never give up. Love water & coffee all day. Only eat berries, little carbs and love protein & salads & green veggies. Thx for this training 💪
Best diabetes and insulin resistance explanation on the Internet ever.. I have watched Dr berg and many others, and they explain things well too, but not as clear, simple and effective as this one.. I think lecturing is a skill, this guy with his presentation and also how he goes into details are perfectly balanced.. I didn't have a professor in uni who can tell topics as effective and as simple as this guy, thanks
Thank you for this. This is amazing content. Please keep it up. My GP doesn't even come close to explaining things in this level of detail. Your work is very important for patients. How are we supposed to take care of ourselves if we don't understand our condition?
Looking forward to the content on stress effects on blood sugar regulation, particularly if you could touch upon elevated lvls of cortisol! Thank you for this concise and informative video :)
Excellent presentation. Diagnosed as T2 at age 45. Panicked…ignorant…250 lbs. my endocrinologist is excellent . Now almost 84…185 lbs….A1C between 6.2-6.5. Feel wonderful….no complications. But…a long road of exercise, dietary education and discipline. Lucky guy.
Glucose effectiveness is intriguing. Your channel is one if the credible/trusted source in the area of nutrition. Wish you can do it more often. 🥰 Greeting from Thailand.
I'm looking forward to your videos on dietary interventions! I've had type 2 diabetes for 21 years now, ever since I was 17. I had an A1c result of 13.3 recently, and was finally fed up and switched to very low carb + intermittent fasting (~19+5). In about a month I'm down to an estimated average glucose of ~90 (according to my calculations). I'm always in the 70-110 range. I still take metformin and occasionally a tiny dose of a sulfonylurea, but I'm slowly trying to phase those out and see how I do.
Wonderful, and congratulations. Thank you for sharing. I cannot give any personal dietary or medical advice here, but if this was my situation, now that blood glucose looks like it's mostly under control, I would now work with my primary care doctor to focus on other risk factors for chronic disease (serum lipids, blood pressure, biomarkers of inflammation, micronutrient status) to make sure that my dietary changes have not created unwanted problems elsewhere.
I recently did the same and brought my AIC from 8.2 to 5.9 however I reduced my inflammatory levels from 27.1 to 5.1 in just 6 weeks - I’m still taking 1,000 mg daily Metformin- how much do you take?
@@gloriasaliba3395 I've been taking 2,000 mg a day. Half in the morning, half in the evening. My babe right now are walnuts. I could eat those until they're gone. So I try not to get too many... Overall, it's going well. Minor setbacks hete and there but the general trend is improving
@@liferidar9554 removed most processed carbs sugar and grains - focussed on good quality protein, good fats, salads and vegetables - ate within a 6-10 hour window - skipped breakfast most days - first meal at 12.30pm-1pm, ate large volumes of salads vegetables - drank 3 litres of water every day, walked 5-10,000 steps and did resistance training twice per week - also started taking supplements - Vit D3, K2, multivitamin, magnesium and collagen - drank back coffee tea occasional Diet Coke - allowed myself 1-2 glasses of wine when dining out and sharing a dessert, certainly not every day
Excelent content. I knew a lot of what you have mentioned, but this video helped me to connect the dots and get a spherical understanding. Please keep up with this series.
Mind boggling. 5.4 grams of sugar in your entire bloodstream at a fasting state of 90 mg/dl. The human body is amazingly efficient and an absolute technical marvel!
An excellent and informative video...thank you. I think part of the reason you were able to impart so much information in a relatively short video is that there was no "bloat"...no excess words or personal asides. Very helpful content!
I've had to go over this a few times but you have explained in detail all the questions that I have had about this subject. Thank you so very very much. It helps me in my quest to reverse my insulin resistance
Thank you for this video. It’s one of the best diabetes videos I’ve seen. Clearly & methodically explained- the summary was excellent. All in all, Very helpful for those of us struggling w/insulin resistance. Appreciate it & Look fwd to your other presentations on this topic.
I can't wait to see your next videos. They are very informative and helpful. I appreciate the effort put into providing professional and in-depth knowledge and at the same time making the information understandable to everyone.
Thank you so much for a very detailed and well explained presentation. A first class example of teaching to me and fascinating new information. I'm looking forward to your other videos.
Very nourishing! Filled with useful information delivered in a conversational style. And not overly long. Thank you! Can wait to digest other videos. We have a health related small group at our church. Your video on How to Avoid Blood Sugar Spikes is already on the docket for a future group discussion.
Thank you for taking time to leave your kind feedback, David. And what a great idea to have a health-related group at church. I am honored to make an appearance there. Best wishes, Mario
Thank you for sharing your knowledge and expertise to the many people that are prediabetic or Diabetic, and more important, bringing to attention the problem of metabolic desease not many people are aware of. I have viewed many of your videos, I turned 70 yrs old last May, I have an A1C3 of "5.7%" last April, I'm skinny, 5' 6" weigh 112 lbs, but Asian, by nature we're small, 80% vegetarian, and exercise and go to the gym 2-3 times a week since young, although I am lacking some exercise outside those days I am sedentary. I would appreciate very much if you can inform me the areas I need to improve so I can be Insulin sensitive, thank you so much!
Can I suggest these videos here to figure out if you are insulin resistant and - if so - what the cause of that may be: ua-cam.com/video/OZtxodqOBbw/v-deo.htmlsi=n33oxruPIh4lz68r ua-cam.com/video/HYtnlRCq83s/v-deo.htmlsi=zstOCLv04NcS6ECF Cheers Mario
Thank you. For the last year, I have been trying to understand and do anything I can to reduce my insulin sensitivity. I am anxiously awaiting your videos on how to improve it. That said, this is the first time I have ever heard of glucose effectiveness even after years of research. I am intrigued to see anything I can do to improve that aspect of sugar metabolism as well. I say all of this to say that the information you provide and the fashion in which you provid it is the most helpful I have ever found including all my conversations with physicians, nutritionists, and personal research. Thank you so much for putting it all out there.
Thanks for a well presented lecture on this issue, as a I am a new Type 2 Diabetic (6 months now). As is my nature to not just follow what my Doctor says alone - but to try to fully understand what the reasons are he is prescribing a particular treatment and why. Unfortunately Doctors only have 6 to 10 minutes per visit for a standard fee and it is insufficient to explain what he knows - So instead I just get told what to do. To counter this I have been exploring everything I can get on UA-cam and I have learnt a lot these past few months. But your presentation was brilliant - in particular the supporting diagrams used - which really helped to explain the process. I have just now subscribed and look forward to learning more ...
You are so very right. It is same scenario in my country 🇳🇬. Doctors are anxious to push you out of the room when they feel they don't have any new developments \ information to gain from a patient to help them pass their exams for higher qualifications, write thesis\journals etc. for their promotion. They don't make effort to research to help patients when they feel they already have the ready made textbook prescriptions & they make the patient feel like a pest.
Thanks so much.👍 Please continue the technicalities, it helps to understand more. Also include full names of acronyms used to demystify them & help to understand their functions & activities. Apart from the fact that I'm a Pharm. by training, the current trend as you know is patients' involvement in their own health management & many patients conduct researches on their health issues even without medical training. So it's good to get comprehensive information from honest forthright experts like you whose primary motive is health, wellness & correct understanding, treatment & management. When a presentation is accurate /factual, the length will not matter to a patient who needs the knowledge to understand their situation & help in their own health management. In conducting researches, many patients have fallen victims to wrong information from people who just want to be heard & make money from the little & inaccurate knowledge they have. This is your 3rd presentation I have seen recently. Very well appreciated ❤
Thank you for your feedback. Just looking at my own comment section and e-mail inbox I can certainly tell that many people have fallen prey to almost cult-like diet tribes that perpetuate dangerous misinformation. Cheers Mario
Yes, I will for sure, and also the other way around (fat effects on insulin metabolism), because it seems to me that most people mistakenly think that only carbs have a negative impact on insulin secretion and action. Cheers Mario
Thank you for this video! I would give it 10 thumbs up if I could. This is one of the most straight forward informative videos I've found on this subject. Your hard work on this video is greatly appreciated!
I ve learnt lots on this topic from Dr. Ben Birkman, but I still enjoy your very educative video. I am looking forward to seeing more videos from your channel. Thank you!
Sorry ... I admit, the body is complex. However, the information is IMO critical to really understanding diabetes, and what can be done about it. So, I think it's worth the effort, but then ... I am biased ...;-) Cheers Mario
Thank you very much for this video! My husband is pre-diabetic and we walk for 35 minutes after a meal. Is there an optimal time after eating to start our walk? You said you start with in 30 minutes of finishing a meal and I just wanted to check if there was an optimal time to start. Thank you so very much for your help!
Thank you very much for your video - with a plethora of videos on the subject and a lot confusion and lack clarity on what sugar is ?? in simple term that a layman like me can understand and came across your video by accident! looking for a video on Hebrew language and yours pop up !! why?? don't know! and I am not complaining either but I was very happy to listen and it was refreshing and clear!! Thank you looking forward to the next one.
Thank you for explaining insulin sensitivity and the regulation of blood sugar levels in such a way that is easy to understand. One thing I have been wanting to know is did I do anything in my earlier years to cause my diabetes such as drinking too many sugary drinks. Hopefully you can answer that question in a future video or reply to my comment. Thank you again. Your videos are very informative. 34:34
Yes.. eating/drinking too much sugary foods in a long term make insulin resistance. It takes around 10-15 years to a diabetic condition from pre-diabetic condition. So if you got diabetic condition at 40 yr old, then perhaps you have pre diabetic condition at 25 - 30 yrs old. Change your diet and intermittent fasting will improve your diabetic condition. I hope that help.
Thank you very much. After watching numerous videos, this was one of the most informative I seen on the subject and touched on completely new areas which I was not aware of.👍
I would love to see the video that says --- you have a body that is glucose intolerant - these are the daily habits one must do to move the body back to insulin sensitivity and glucose tolerance.
I was diagnose for type 2 diabetis and the effect for me was i,m lossing weight. Before I was diagnose my weight was 65kg but now its only 51 to 52 .I wish if you could explain whats happening in this case I have.Ty you Doc.
There are a number of things that happen with untreated diabetes that can lead to weight loss. For one, in type 2 diabetes, people are insulin resistant, and their pancreatic beta-cells are unable to produce enough insulin. This creates an insufficient insulin signal in all target cells, including in fat cells. And because insulin is needed to store fat effectively, the body's ability to store fat long term declines. Also, people with diabetes by definition have elevated blood sugar levels. And once the blood sugar levels increase to over 180 mg/dL (10 mmol/L), the kidneys start to secrete sugar in the urine. That is why people with diabetes tend to urinate (and drink) so much. If someone has untreated diabetes, with very high glucose levels excesseding 180 mg/dL all day, they will lose a lot of energy/calories by excreting sugar through the urine, so that could also explain weight loss. So, whatever the reason, it is important to seek care and be treated apropriately so that blood sugar levels can be below 180 mg/dL all of most of the time. Best, Mario
Excellent presentation. We'll done. Taught me something new i. e. ; Glucose Effectivness, which I m going to investigate further because based on my own experience I have always felt that glucose regulation could not solely depend on Insulin secretion but never been able to confirm it. Once more thanks for sharing this knowledge with us.
I am interested in learning how insulin resistance is affected by hypothyroidism after a total thyroidectomy (the treatment for thyroid cancer). I sense glucose tolerance and insulin sensitivity are getting worse, year by year, during the 11 years since thyroidectomy. Does taking thyroid hormone therapy affect insulin resistance?
Best explanation of diabetes I have seen. excellent addition to info from my doctor(s). Very clear and easy to understand. Am forwarding a link friends with diabetes. Thank you.
If fasting blood sugar doesn't drop below 89 for 12 weeks of severely restricted sugar/carbs intake, but then drops to 69 suddenly, what could be reason?
Normal fasting blood glucose level = 80-100 mg/dl. Maintained by glucagon and gluconeogenis from protein. Normal postmeal blood glucose level = Normal ( OGTT) Oral glucose tolerance test Fasting level = less than 100 mg/dl After glucose ingestion level = less than 140 mg/dl ( at the 2 hour mark of OGTT) Prediabetes level in OGTT = less than 126 to less than 200 mg/dl Diabetes levels in OGTT : Fasting level : Equal or more than 126 mg/dl Post-ingestion level : equal or more than 200 mg/dl.
Technically you are correct that glucose can be excreted through the urine, but this doesn't occur in meaningful amounts at glucose concentrations below the renal threshold of glucose, which is at about 180 mg/dL (10 mmol/L). And blood glucose does not exceed 180 mg/dL under physiological conditions, i.e., in people who are fully glucose tolerant. But, you are correct, it is an insulin-independent mechanism of removing glucose from the blood in people with diabetes. Cheers Mario
Keep up the good work. One of the most informative videos that we ever had. Though some of your talks are a little hard for the layman to fully digest, they are incredibly eye opening. Perhaps, we just need to go thru the videos several times to digest the messages.
Small correction: At time point 7:10, I say that "In liver, muscle, and fat tissue, insulin binds to the insulin receptor on the surface of cells, and that causes a specific glucose transporting molecule called GLUT-4 to be transported to the cell membrane". This is not correct, because GLUT-4 doesn't play a major role in glucose transport in the liver (where it's other glucose transporters such as GLUT-2). In muscle and fat tissue it is GLUT-4, however, so that part is correct.
❤❤❤❤❤❤😊😊😊😊❤❤❤
Another correction would be:
Mono - a prefix that means "unique" or "single."
Not "One."
@@ataho2000 hahahahaha, you're joking right? If not, rule #1 of correcting people is to actually be correct. You got us though, I'm still laughing... 'mono' can't mean 'one', hahahahhahahahha.... nice mono, uh, I mean nice one.
@atoms.channel I don't know Greek but they told me that they use "ena" for one and "mono" for single.
Care to teach Greek People how to speak Greek?
I don't know what to call this, Ignorance, arrogance or .........
@@atoms.channel On second thoughts, my mistake. English people have the tendency to take words from foreign languages ad bastardize them to their harts content so you can use the word "mono" any way you want.
I am 72yrs. Old and 20yrs. T2 diabetic. This channel is the best for diabetics. Excellent presentation. A big thank you.
Thank you, Jacob!
Truly Best
Very clear and understandable information. I am watching videos like this and try to manage my food and activities for better health. In about 8 months I lost 52 lbs and I maintained the new weight for tw years. Now after two years my Hba1c dropped to 5.2 and am really happy because I am no more a pre diabetic person. Eat twice a day and walk about 4 miles a day.
Congrats! That's great to hear. I really do believe in the power of taking responsibility to ones own health, rather than thinking about health care only as something that is done to us.
Cheers
Mario
That's fab it's great to here positive out comes
Would you mind sharing what you eat?
wow. excellent
I am 71 yrs old, very active, slim 5'10". T2 for 15 yrs. Never knew about IR. Had T2 hubs so very little extra calories like gravy, biscuits etc. He followed ADA diet so had normal carbs with lunch & dinner. Was a pharmacist, checked his blood 8 times a day, and diabetic for 63 yrs. Had limited activities therefore, he had every complication. I can not do this to my family. My a1c always 7.3 & 7.5 and I must get into 6's. CGM last year & I love it. My numbers spike with many meals and trying to fast more. Always eat 1/2 restaurant meal. I am emptying my garage and doing way too much lifting, painting, cleaning, moving fridges and I just lifted 5 drawer tool chest. I just do not expect good numbers anymore. I joined hiking club and never walking on level ground. Loved it. I am desperate to save my organs. On 5 glucose meds & Toujeo insulin. Just sharing as there is something I am missing. I will never give up. Love water & coffee all day. Only eat berries, little carbs and love protein & salads & green veggies. Thx for this training 💪
@@Franklin-pc3xd She said she is a slim 5'10"
Anxiety may be the issue, just meditate and do yoga, SUN SALUTE aka SURYA NAMASKAR , if u want to 😊
@@okundola9388 TOFI ?
@@yangtse55 What is TOFI please ?
Thin on the outside fat on the inside……TOFI
Best diabetes and insulin resistance explanation on the Internet ever.. I have watched Dr berg and many others, and they explain things well too, but not as clear, simple and effective as this one.. I think lecturing is a skill, this guy with his presentation and also how he goes into details are perfectly balanced.. I didn't have a professor in uni who can tell topics as effective and as simple as this guy, thanks
What a great video by a responsible clinician. What clarity!
I’ve had Type 1.5 diabetes for 20+ years and I’ve learned something new. I’m now a subscriber and can’t wait to binge watch your channel.
The best explanation of this subject I have ever watched. Many thanks and keep up the great work!
I agree. He is very clear
This is absolutely the BEST content on this topic!
Thank you for this. This is amazing content. Please keep it up. My GP doesn't even come close to explaining things in this level of detail. Your work is very important for patients. How are we supposed to take care of ourselves if we don't understand our condition?
Thank you for the kind comment, Luiz. Appreciate you taking the time.
um, let the pharmaceuticals make money from it.
Sure
@@yoya4766❤
This is hands down the best explanation of what causes diabetes I have seen so far in my quest to understand the disorder.
I really appreciate your "recaps" toward the end of the videos. And they are easy to understand
Thank you very much. This is by far the most understandable explanation I have ever seen on the topic.
Thank you so much. It's always challenging to know how detailed these videos should be, so I appreciate the feedback.
Looking forward to the content on stress effects on blood sugar regulation, particularly if you could touch upon elevated lvls of cortisol! Thank you for this concise and informative video :)
Ditto!
Excellent presentation. Diagnosed as T2 at age 45. Panicked…ignorant…250 lbs. my endocrinologist is excellent . Now almost 84…185 lbs….A1C between 6.2-6.5. Feel wonderful….no complications. But…a long road of exercise, dietary education and discipline. Lucky guy.
Congrats for controlling your T2DM so well. And thank you for the kind feedback.
Best wishes,
Mario
The glucose effectiveness section at the end was really interesting.
Glucose effectiveness is intriguing. Your channel is one if the credible/trusted source in the area of nutrition. Wish you can do it more often. 🥰 Greeting from Thailand.
Thank you. I took an (unplanned) pause this summer due to some personal reasons. I am planning to post more regularly going forward.
I'm looking forward to your videos on dietary interventions! I've had type 2 diabetes for 21 years now, ever since I was 17. I had an A1c result of 13.3 recently, and was finally fed up and switched to very low carb + intermittent fasting (~19+5). In about a month I'm down to an estimated average glucose of ~90 (according to my calculations). I'm always in the 70-110 range. I still take metformin and occasionally a tiny dose of a sulfonylurea, but I'm slowly trying to phase those out and see how I do.
Wonderful, and congratulations. Thank you for sharing.
I cannot give any personal dietary or medical advice here, but if this was my situation, now that blood glucose looks like it's mostly under control, I would now work with my primary care doctor to focus on other risk factors for chronic disease (serum lipids, blood pressure, biomarkers of inflammation, micronutrient status) to make sure that my dietary changes have not created unwanted problems elsewhere.
I recently did the same and brought my AIC from 8.2 to 5.9 however I reduced my inflammatory levels from 27.1 to 5.1 in just 6 weeks - I’m still taking 1,000 mg daily Metformin- how much do you take?
@@gloriasaliba3395 I've been taking 2,000 mg a day. Half in the morning, half in the evening. My babe right now are walnuts. I could eat those until they're gone. So I try not to get too many... Overall, it's going well. Minor setbacks hete and there but the general trend is improving
@@gloriasaliba3395 how did u manage your A1C and Inflammatory levels? can u please share ?
@@liferidar9554 removed most processed carbs sugar and grains - focussed on good quality protein, good fats, salads and vegetables - ate within a 6-10 hour window - skipped breakfast most days - first meal at 12.30pm-1pm, ate large volumes of salads vegetables - drank 3 litres of water every day, walked 5-10,000 steps and did resistance training twice per week - also started taking supplements - Vit D3, K2, multivitamin, magnesium and collagen - drank back coffee tea occasional Diet Coke - allowed myself 1-2 glasses of wine when dining out and sharing a dessert, certainly not every day
LOVED THIS and I've been a very studied Type 1 Diabetic for 23 yrs!! Thank you!! (Wish I could find an educated Endo like you!!)
This is mind blowing content! The simplicity and effectiveness of this video is really beyond words!
Hats off Sir.
Appreciate your feedback. Glad you found it helpful.
Cheers
Mario
Amazing illustrations, breaking this complex topic down so well, to the lay person! Thank you, Dr. Kratz!
Your videos are so well explained and extremely helpful.
And btw - your English is perfect.
Greetings from Austria.
This was by far the best video I watched in this topic. I watched it twice back to back! Thank you so much for your effort ❤
Thank you for the feedback! It's always hard to know how deep to go without boring everyone, so it's good to get this kind of feedback.
Cheers
Mario
Excelent content. I knew a lot of what you have mentioned, but this video helped me to connect the dots and get a spherical understanding. Please keep up with this series.
Mind boggling. 5.4 grams of sugar in your entire bloodstream at a fasting state of 90 mg/dl. The human body is amazingly efficient and an absolute technical marvel!
The work of God ❤🙏🏻
Such clarity, comprehensiveness in the video. Can't wait for other videos in the series
Thank you!
An excellent and informative video...thank you. I think part of the reason you were able to impart so much information in a relatively short video is that there was no "bloat"...no excess words or personal asides. Very helpful content!
Well done
Clearly explained
Amazing
Thank you
Awesome explanation. I am now watching this channel frequently. Thank you!
Such valuable information all in one place that I've been trying to piece together for years. Thank you!
Blows my mind many of you have been T2D for 10s of years. I'm barely preD for 1.5 years and already lost and arm and leg.
😢
I've had to go over this a few times but you have explained in detail all the questions that I have had about this subject. Thank you so very very much. It helps me in my quest to reverse my insulin resistance
awesome to see you posting again. always gems from this channel. :D
Thank you. And sorry for the extended pause.
@@nourishedbyscience you're welcome and that's understandable!
Wow! Fascinating information and well presented . Thank you!
Thank you for this video. It’s one of the best diabetes videos I’ve seen. Clearly & methodically explained- the summary was excellent. All in all, Very helpful for those of us struggling w/insulin resistance. Appreciate it & Look fwd to your other presentations on this topic.
Very happy to see you're back!
Very clear and informative presentations thank you so much
I can't wait to see your next videos. They are very informative and helpful. I appreciate the effort put into providing professional and in-depth knowledge and at the same time making the information understandable to everyone.
Excellent video thank you
This is so important to understand as diabetes is becoming so common
Thank you so much for a very detailed and well explained presentation. A first class example of teaching to me and fascinating new information. I'm looking forward to your other videos.
Extremely clear and concise! Can’t wait your next post!
This is by far the most informative channel that i have come across in this domain. Thank you so much and looking forward to more videis!
Very nourishing! Filled with useful information delivered in a conversational style. And not overly long. Thank you! Can wait to digest other videos. We have a health related small group at our church. Your video on How to Avoid Blood Sugar Spikes is already on the docket for a future group discussion.
Thank you for taking time to leave your kind feedback, David. And what a great idea to have a health-related group at church. I am honored to make an appearance there.
Best wishes,
Mario
Is this a group online?
Great content. Clearly explained. Thank you.
Thank you for sharing your knowledge and expertise to the many people that are prediabetic or Diabetic, and more important, bringing to attention the problem of metabolic desease not many people are aware of. I have viewed many of your videos, I turned 70 yrs old last May, I have an A1C3 of "5.7%" last April, I'm skinny, 5' 6" weigh 112 lbs, but Asian, by nature we're small, 80% vegetarian, and exercise and go to the gym 2-3 times a week since young, although I am lacking some exercise outside those days I am sedentary. I would appreciate very much if you can inform me the areas I need to improve so I can be Insulin sensitive, thank you so much!
Can I suggest these videos here to figure out if you are insulin resistant and - if so - what the cause of that may be:
ua-cam.com/video/OZtxodqOBbw/v-deo.htmlsi=n33oxruPIh4lz68r
ua-cam.com/video/HYtnlRCq83s/v-deo.htmlsi=zstOCLv04NcS6ECF
Cheers
Mario
You are a very good teacher. Your explanation is very clear. How you speak is soft and it helps to hear well.
GOD BLESS YOU
Thank you. For the last year, I have been trying to understand and do anything I can to reduce my insulin sensitivity. I am anxiously awaiting your videos on how to improve it.
That said, this is the first time I have ever heard of glucose effectiveness even after years of research. I am intrigued to see anything I can do to improve that aspect of sugar metabolism as well.
I say all of this to say that the information you provide and the fashion in which you provid it is the most helpful I have ever found including all my conversations with physicians, nutritionists, and personal research. Thank you so much for putting it all out there.
Thank you for the kind feedback!
Best wishes,
Mario
Excellent! Can’t wait to see more from your channel on this topic!!
Thank you, Yoshiko!
These explanations are the best I have seen.
Very informative. Which we understand the basic information regarding insulin for non medical people. Thank you.
Thanks for a well presented lecture on this issue, as a I am a new Type 2 Diabetic (6 months now). As is my nature to not just follow what my Doctor says alone - but to try to fully understand what the reasons are he is prescribing a particular treatment and why. Unfortunately Doctors only have 6 to 10 minutes per visit for a standard fee and it is insufficient to explain what he knows - So instead I just get told what to do. To counter this I have been exploring everything I can get on UA-cam and I have learnt a lot these past few months. But your presentation was brilliant - in particular the supporting diagrams used - which really helped to explain the process. I have just now subscribed and look forward to learning more ...
You are so very right. It is same scenario in my country 🇳🇬. Doctors are anxious to push you out of the room when they feel they don't have any new developments \ information to gain from a patient to help them pass their exams for higher qualifications, write thesis\journals etc. for their promotion. They don't make effort to research to help patients when they feel they already have the ready made textbook prescriptions & they make the patient feel like a pest.
This is gold. Amazing job!
So well explained , so helpful
Thanks so much.👍
Please continue the technicalities, it helps to understand more. Also include full names of acronyms used to demystify them & help to understand their functions & activities.
Apart from the fact that I'm a Pharm. by training, the current trend as you know is patients' involvement in their own health management & many patients conduct researches on their health issues even without medical training.
So it's good to get comprehensive information from honest forthright experts like you whose primary motive is health, wellness & correct understanding, treatment & management.
When a presentation is accurate /factual, the length will not matter to a patient who needs the knowledge to understand their situation & help in their own health management.
In conducting researches, many patients have fallen victims to wrong information from people who just want to be heard & make money from the little & inaccurate knowledge they have.
This is your 3rd presentation I have seen recently.
Very well appreciated ❤
Thank you for your feedback.
Just looking at my own comment section and e-mail inbox I can certainly tell that many people have fallen prey to almost cult-like diet tribes that perpetuate dangerous misinformation.
Cheers
Mario
Great video as always. Could you talk about the effect insulin and insulin resistance on fat metabolism?
Yes, I will for sure, and also the other way around (fat effects on insulin metabolism), because it seems to me that most people mistakenly think that only carbs have a negative impact on insulin secretion and action.
Cheers
Mario
The human body has some amazing abilities and this video illustrates a few of them. This is clearly evidence of a higher power, a Creator of us all.
So helpful. Thank you!
Thank you for this video! I would give it 10 thumbs up if I could. This is one of the most straight forward informative videos I've found on this subject. Your hard work on this video is greatly appreciated!
thank you for making these videos. very well explained.
Absolutely best reporting of body function from glucose intake
I ve learnt lots on this topic from Dr. Ben Birkman, but I still enjoy your very educative video. I am looking forward to seeing more videos from your channel. Thank you!
Thank you, Mary. Appreciate your feedback.
Cheers
Mario
It’s Ben Bikman he’s awesome
Best discussion on the internet! Thank you
I love this.
I've been very much informed by your video nd hope to get more.
Thank you
make a video on how to avoid insulin resistance
I wish i was smart enough to follow this in depth lesson, information overload. I'll have to rewatch.
Sorry ... I admit, the body is complex. However, the information is IMO critical to really understanding diabetes, and what can be done about it. So, I think it's worth the effort, but then ... I am biased ...;-)
Cheers
Mario
Just love these videos. So useful for the patient.
Amazing presentation! Very informative and clearly explained.
Thank you very much for this video! My husband is pre-diabetic and we walk for 35 minutes after a meal. Is there an optimal time after eating to start our walk? You said you start with in 30 minutes of finishing a meal and I just wanted to check if there was an optimal time to start. Thank you so very much for your help!
I just found your channel an I will be a constant follower. You explain things well enough for me understand somewhat. Thank you.
Sir you have shared very valuable information with us we are thankful and God bless you for your hard work and dedication.
Love from India
Thank you for clearly explaining how IR works. Looking forward to more videos and learning how to manage effectively.
Thanks so much for the best information on blood sugar regulation I have found 🙏
Excellent presentation. Love your straightforward approach. Binge watching your videos.
Thanks for this information, kindly do a video on how to reverse prediabetic with low BMI... Any dietary suggestions?
Excellent presentation of the material! Thank you so much for doing this!
Thank you very much for your video - with a plethora of videos on the subject and a lot confusion and lack clarity on what sugar is ?? in simple term that a layman like me can understand and came across your video by accident! looking for a video on Hebrew language and yours pop up !! why?? don't know!
and I am not complaining either but I was very happy to listen and it was refreshing and clear!! Thank you looking forward to the next one.
Brilliant, the clearest explanation I have seen on this subject. looking forward to learning more.
Thank you for explaining insulin sensitivity and the regulation of blood sugar levels in such a way that is easy to understand. One thing I have been wanting to know is did I do anything in my earlier years to cause my diabetes such as drinking too many sugary drinks. Hopefully you can answer that question in a future video or reply to my comment. Thank you again. Your videos are very informative. 34:34
Yes.. eating/drinking too much sugary foods in a long term make insulin resistance. It takes around 10-15 years to a diabetic condition from pre-diabetic condition. So if you got diabetic condition at 40 yr old, then perhaps you have pre diabetic condition at 25 - 30 yrs old.
Change your diet and intermittent fasting will improve your diabetic condition. I hope that help.
Great work! We need more content regarding Insulin-Independent Glucose Regulation!!!
Thank you very much. After watching numerous videos, this was one of the most informative I seen on the subject and touched on completely new areas which I was not aware of.👍
Best explanation and context around!
I would love to see the video that says --- you have a body that is glucose intolerant - these are the daily habits one must do to move the body back to insulin sensitivity and glucose tolerance.
I was diagnose for type 2 diabetis and the effect for me was i,m lossing weight. Before I was diagnose my weight was 65kg but now its only 51 to 52 .I wish if you could explain whats happening in this case I have.Ty you Doc.
There are a number of things that happen with untreated diabetes that can lead to weight loss. For one, in type 2 diabetes, people are insulin resistant, and their pancreatic beta-cells are unable to produce enough insulin. This creates an insufficient insulin signal in all target cells, including in fat cells. And because insulin is needed to store fat effectively, the body's ability to store fat long term declines. Also, people with diabetes by definition have elevated blood sugar levels. And once the blood sugar levels increase to over 180 mg/dL (10 mmol/L), the kidneys start to secrete sugar in the urine. That is why people with diabetes tend to urinate (and drink) so much. If someone has untreated diabetes, with very high glucose levels excesseding 180 mg/dL all day, they will lose a lot of energy/calories by excreting sugar through the urine, so that could also explain weight loss.
So, whatever the reason, it is important to seek care and be treated apropriately so that blood sugar levels can be below 180 mg/dL all of most of the time.
Best,
Mario
@@nourishedbyscience ty doc. God bless.
Excellent explanation & thank you. Well done 👏
Thank you for the new info on Glucose Effectiveness. This could help to explain how the hunger signal is mediated in a long fasted state.
Thanks Dr. a new approach to understanding glucose and how to keep it lower.
Thank you Dr Kratz for your clear explanation.
Excellent presentation. We'll done. Taught me something new i. e. ; Glucose Effectivness, which I m going to investigate further because based on my own experience I have always felt that glucose regulation could not solely depend on Insulin secretion but never been able to confirm it. Once more thanks for sharing this knowledge with us.
You are a great scientist and communicator.
I am interested in learning how insulin resistance is affected by hypothyroidism after a total thyroidectomy (the treatment for thyroid cancer). I sense glucose tolerance and insulin sensitivity are getting worse, year by year, during the 11 years since thyroidectomy. Does taking thyroid hormone therapy affect insulin resistance?
Thank you for an eye-opening presentation of glucose and the manifold ways the body uses to keep it at a tolerable level.
Best explanation of diabetes I have seen. excellent addition to info from my doctor(s). Very clear and easy to understand. Am forwarding a link friends with diabetes. Thank you.
Thank you for your kind feedback, Ed.
Best,
Mario
If fasting blood sugar doesn't drop below 89 for 12 weeks of severely restricted sugar/carbs intake, but then drops to 69 suddenly, what could be reason?
Will it help taking pancreatic enzymes supplement to improve sensitivity
Greatly appreciated; thank you. I have been watch binging on your videos. Knowledge is power. God bless all of you at "Nourished by Science"!
Normal fasting blood glucose level = 80-100 mg/dl. Maintained by glucagon and gluconeogenis from protein.
Normal postmeal blood glucose level =
Normal ( OGTT) Oral glucose tolerance test
Fasting level = less than 100 mg/dl
After glucose ingestion level = less than 140 mg/dl ( at the 2 hour mark of OGTT)
Prediabetes level in OGTT = less than 126 to less than 200 mg/dl
Diabetes levels in OGTT :
Fasting level : Equal or more than 126 mg/dl
Post-ingestion level : equal or more than 200 mg/dl.
Good information. I am surprised you didn't mention urination as an insulin independent removal mechanism.
Technically you are correct that glucose can be excreted through the urine, but this doesn't occur in meaningful amounts at glucose concentrations below the renal threshold of glucose, which is at about 180 mg/dL (10 mmol/L). And blood glucose does not exceed 180 mg/dL under physiological conditions, i.e., in people who are fully glucose tolerant. But, you are correct, it is an insulin-independent mechanism of removing glucose from the blood in people with diabetes.
Cheers
Mario
Keep up the good work. One of the most informative videos that we ever had. Though some of your talks are a little hard for the layman to fully digest, they are incredibly eye opening. Perhaps, we just need to go thru the videos several times to digest the messages.
Yes
Very clear and helpful.
Well explained but it is too lengthy.
Very easy to understand and follow along. Thank you!
Wow! Incredible information! Thank you!