COVID-19 | Coronavirus: Epidemiology, Pathophysiology | APRIL UPDATE
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- Опубліковано 28 тра 2024
- This Video Was Posted April, 2020. As the COVID-19 Pandemic is always evolving, the information presented this is video may no longer reflect current findings and research.
Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
In this lecture Professor Zach Murphy will present on COVID-19- Coronavirus: Epidemiology, Pathophysiology | APRIL UPDATE.
Join us for our lecture on COVID-19 where we will go into detail on the virology, epidemiology, and pathophysiology/pathology of COVID-19. This is our April update on our previous lecture to keep all of our viewers informed on the new research and publications that have been released on COVID-19. Please be aware- This lecture is up to date as of April 17, 2020. We hope you enjoy this lecture and be sure to support us below!
Outline:
00:00 - Intro
00:15 - Virology Overview
04:52 - Zoonotic Theories (Homologous Recombination))
07:57 - SARS COV2 "S" and "L" Variants
10:43 - Epidemiology
13:36 - Rate of Transmission
18:25 - Pathophysiology
23:03 - Infection Methodology
28:27 - Interferon Interactions
42:40 - Multi-System Organ Damage
45:40 - ACE-2 Issues
46:46 - Wrap up
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#COVID #ninjanerd #covid_19
This is brilliant. He makes the terrifyingly incomprehensible completely understandable without patronising anyone. Probably one of the most crucial Channels on the Internet!
I've never waited for a youtube video my entire life. Here I am today.
Me too
Same here
Mee too
same
I guess the coronacrisis also gave you the time to wait for it ;)
At last, somebody who treats non-specialists like they have some intelligence. Fantastic presentation. Thank you!!
ALL of these COVID update videos should be required watching for ANYONE that feels the need to share their opinions or make POLICY DECISIONS for our country.
Zach, you are the best teacher ever!
UA-cam already deleted my vid. They only want you to see what “they” want. This is to let the public know what going on behind the scenes of the #covid19. No murder, no nudity, no foul language, no brutality etc. but they deleted it. Well here’s the video facebook.com/groups/182925502307935/permalink/600504167216731/
This is rubbish if you can't provide a cure. Ginger, garlic, and lemon cooked together, then grounded and drained into a cup and taken orally, would prevent the virus from attack. Pure and simple.
@@dividivoo any proof or you just heard it from your grandmother as I heard about the monsters and the flat earth from flatted brain people???
As a biomedical researcher, I think it's amazing to see how fast research progresses once enough funding is provided. In 2020 alone, clinical phase III trials have already started which test HIV or Ebola drugs (and might be successful to some degree), an antibody against SARS-CoV-2 has been developed and and vaccines are developed by over 80 institutions (I just published a video about recent COVID-19 breakthroughs). Last week, scientists also found out that SARS-CoV-2 is currently not able to infect dogs or lifestock but might unfortunately be able to infect cats. Great video, I'm enjoying it!
Bill gates helped to get this running with dr Fauci, who says 3 years before that a pandemic is coming but yet cant have a vaccine, uhuh Bill Gates loves generic and hates over population
Would the fact that it infects cats provide evidence that the disease pass over to humans via civets?
Life Lab Learner, for the queries re cats, this veterinarian is a world expert on zoonoses: www.wormsandgermsblog.com/2020/04/articles/animals/cats/covid-19-infected-cats-new-york/
Life Lab Learner money talks! Let’s treat poverty the same way. Pool our money together, put the best minds on it, and shit will be solved almost overnight
😿
I am from srilanka my biochemistry teacher asked questions about COVID 19 and test and techniques i only referred your video and she said " well done i think you have done a phd on COVID 19"
Thanks a lot for your service. When Anthony retired, I pray that the government will recognize your knowledge and experience and place you in a position for every American to learn from you... Kudos 👍
39:18, asks a rhetorical question, "I'm glad you asked guys"
huh?
Atanasio Mugambi hahahahahah
I liked that part too! Hahaha!! :D
Thank you...you are an amazing teacher. I studied biology 25 years ago in India and I wish I had a teacher like you....I would have persisted and worked harder. I always loved biology but as a young person, the teachers never engaged or explained. One was expected to rote learn...🙁. But, it’s never too late to learn🙂.
This should be on television! Thanks Zach!
Exactly !! Zach is really a great presenter!!
Good skill into your pen on white board ...fantastic and inspiration to me to teach .....
That Pokemon reference made me happy. The fact that you made this video, with easy to understand illustrations makes me even happier. Thanks for the work you're doing! The media is abhorrent at this point.
Shared with my colleagues who are also professionally into this - they ALL give the thumbs up 👍🏽👍🏽👍🏽👍🏽
It's worth it!!!
This is launched on my birthday, definitely the best gift!
You don’t understand how excited every single video makes me. I would watch these and listen to these all day forever !
GOD BLESS YOU NINJA DOCTOR.....you just gave me the best knowledge so far available with details and in coordination on youtube than any institute can teach me in a whole day........those were golden 47 minutes ....thank you
One word: EXCELLENT!! Two: Standing ovation! :D
I Really understand the anatomy of how Covid-19 enter the systems of the human body and how it affects each system. Great Instructor!!!
I am mesmerized by your knowledge. As a nurse, I studied biology, chemistry, microbiology, epidemiology, pharmacology, etc, but never in this detail. I love your teaching style. Thank you so much. You make it much easier to understand.
This man deserves wayyyyy more subscribers. Big props to him!!!
Love you,,, all the way from AFRICA, (Namibia )
Keep up the good work..
Love how you convert medical words into visual pictures teachings
Last time i studied anything about biology was 7 years ago, but you can break things down so good that I'm able to follow. 10/10
You are just ridiculously amazing! Thank you so much Zach :) This new video was well worth the wait. You are one of the few people I know I can trust with the info you put out-always well researched and evidenced-based. Excellent job synthesizing SO MUCH info ...my mind is blown at how you always pull it off!
Thank you for keeping us updated with the latest news
God bless you and your team.
Hope to see your channel grow to tremendous heights!
You're a G man. Thanks for doing what you do. Believe me, you're appreciated.
Me: *sees a Ninja Nerd video video
*Slams the reminder button 😌
I believe covid-19 may increase inflamation in the brain. Ive had all symptoms: no smell, diarehea, trouble breathing, headaches...etc
@ΛCΞ A doctorate pathway so it seems. He is lecturing an audience who will be tomorrow's doctors. Notice how many times he uses "patient presents to you" symptom A, symptom B. All in all, given what's been discovered since it was a good lecture.
@ΛCΞ could be, but I learned this these principles in a 200 level undergraduate class at a community college. It's the application of those principles that you find in graduate level classes
@ΛCΞ We use it at the Community College level to study for anatomy and physiology courses, also many medical students use their work to study, etc. And regular people can learn from them. I believe Zach is, in fact, in medical school. He's pretty amazing. He should teach and doctor if he can do both at the same time.
@@cristiep7377 he kind makes it fun, doesn't he?
Zach I have to tell you even though my last science class was over 40 years ago in high school your explanations are outstanding! Do I comprehend everything?...no lol but I feel more educated because of you. Thanks
Be safe
Shawn
Zach you guys are national treasures. Absolute national treasures. You do so much good with your information you share and without any agenda behind you other than to explain things so people can understand many different health issues, physiological issues, etc. There isn't enough good I can say for you guys. You spread absolute GOOD with every video you make. You help so many people I know to understand more about many things, and of course, COVID-19 that many are not getting good reliable information because of a variety of issues (chosen sources, etc.). I love you guys. LOVE LOVE LOVE.
I follow you from Bolivia.
I'm preparing for the usmle, keep it up you're great
Setting a reminder for this, can't wait! Woooooo 😎
First time ever i'm waiting for a video on youtube. So excited to learn again.
I am going through the recent COVID 19 resources , and I think this is the perfect starting point to understand the solid papers.
Yes!
Remarkable. Thank you!
The immediate host could a virologist in the Wuhan virology lab.
Zach, could you possibly do a video on how viruses return in different seasons? I cannot wrap my head around how they return
This is the first time I have watched a Ninja Nerd Science video. This is awesome! I am an ICU nurse. This Covid lecture was amazing! Thank you!
Love, love, love your videos on COVID-19. You are an amazing teacher breaking down this complicated system into easy to understand terminology and graphics. Being an ICU nurse front liner, I need to clearly understand what I'm dealing with and your lectures have provided that for me without being boring. Great job!!
"Who's that pokemmoonn" rewatched that bit multiple times. very cute very endearing.
I am so excited about this video. I wish I could teach like you in my own videos, I am still practicing.
Thank you for this AMAZING content.
Your videos are great too!! Dear have a look at mine!!
You guys are the best.
Thanks for everything you all do for the medical community.
I pass most of my exams because of your videos so from the depth of the chambers of my heart, thank you.
Watching these videos of Ninja Nerd Lectures about the coronavirus helps me out to understand much more easier. I'm disabled with seizures so it helps me out a whole lot more. You are a great teacher. Stay safe
My first time to ever wait for a UA-cam video considering how busy I can be, and by the way it’s gonna be midnight here but I don’t mind.. for I expect this to go down with some of the best information we seek out there.. let’s do this Zack Rob Kris
Hey ninja nerd. Great video as usual. I have to correct some of the molecular bio here though. When the spike protein binds to the ace 2, and TMPRSS2 cleaves the spike protein to expose the fusion peptide which inserts into the membrane, the virus doesn’t enter the cell vis endocytosis. It enters via fusion of the host cell membrane and it’s vial envelope and dumps it’s RNA into the cytoplasm. The second thing is the gene expression portion. You are correct when you said that the RNA will be initially translated into polyproteins first. But this is to create the replicate transcriptase complex which will include the rna dependent RNA polymerase. This replicas transcriptase complex then proceeds to transcribe the genes encoding for the structural proteins via a process called discontinuous transcription to produce the sub-genomic mRNAs which will then be translated into the structural proteins.
"It enters via fusion of the host cell membrane and its vial envelope..."
I think from one professional / scholar (you) and a professional colleague (him), you should send him an email directly (and delete your comments) to share your disagreements. This is like contradicting your professor in the middle of his lecture.
He (Ninja Nerd) did great explaining his findings and analysis. It is up to us to take notes (believe him) or decide on leaving his classroom.
@@cadwerks3277 shut up girl
Dear Sir, I don't have words to express about your contribution towards educating us in such a way that person like me who is having non-medical background can also easily understand.
500K Congratulations!!!!!!!! Wish I could celebrate with you and the team!!
Man this guy is smart how old is he?he looks 20 imagine how much he will know by 50 lol....I thank god for making people this smart
Yes. God made him smart.
He's at least 30. He's been doing this for almost a decade, if you watch his oldest videos he looks like he's in his early 20s in them
I also think he has a super brain and practices, I just partied and surfed... but now we're all gonna be poor... jokes aside I only watched 2 v of this guy
He is at least 30 and went to med school & this is the level of detail you study in medical school & graduate school in biology and biomedical science.
@@kasa9884 No, you're wrong. God made him smart.
NNS: *asks a rhetorical question*
NNS: "im glad you asked guys"
That's what makes him a nice teacher.
This video is amazing, it is accessible for everyone. You're an outstanding teacher!
I am looking forward to this video especially since I majoring in Public Health and find it important to keep myself updated on the current status and statistics of the pandemic. I will definitely share this video with my Epidemiology class.
You had me at explaining in layman's terms.
I am really excited for this video!! you are one of the 2 best medical teachers. The other is DR.NAJEEB. We are trying hard to fall in the list. you have exceptional teaching skills and have inspired me alot .
We love you sir your lectures are great too!!Indeed Zach is among 2 best medical teachers.
You are doing great stuff Medicoma!!!
Great video, as always!
Would you be able to provide any insight on the current available knowledge regarding antibodies and potential second infections, especially considering that there are assumed to be the S/ and L/Type?
Thanks in advance!
Zach, you're a truly gifted individual, I love all your videos!!
Squirtle.
Squirtle is the answer to the question.
Final answer.
I loved the pokemon reference in the video! Hilarious!
All in all, this is an excellent video. I've learned so much :)
Wow, this video makes me feel like the part of the movie Wanes World when he meets Alice Cooper, “we are not worthy, we are not worthy”
Best channel ever ! I really spend hours watching your amazing explanations and I was on pins and needles waiting for a new video ! Thanks so much !
Wow, I have never so far, since December heard a decent understandable lecture like this. Brilliant work - you are truly helping those members of society that have some background on physiology and biology, although my higher education is more specific to Natural sciences as I majored in Botany and Zoology. And went on to an Honors degree in environmental science.but this was some time back, and you really help us understand SPECIFICALLY what makes this virus so dangerous, as well as updating us based on the latest research. You are damn brilliant and intelligent, thank you for sharing that knowledge with us in such a down to earth manner. You have a gift in teaching. keep going!!!! Because you made a difference to me way down here in South Africa, and I hope the rest of the world gets to see this. Thank you.
A wild Squirtle has appeared!
takecareofyourshoess 😂😂😂
Would love to watch live but as a respiratory therapist I'll be busy!
Not a problem! The video will be on our channel permanently after the premiere 😄 Thanks for your hard work!
Thank you for your hard work! I am much grateful!
Thanks for this update, very well done.
What a great presentation. On a scale of 1-10, this is a 10.
Informative, Educational, fast paced, intellectually enriching.
A sweeping survey - filled with great technical depth - but explained in a manner that it can be consumed by the average person - with no medical background.
As an Information Technology Architect - I really appreciated the usage of the diagrams (and color-coding) to communicate this information.
There are no words to appreciate you. You are doing a great job by providing us this knowledge . I'll try to share the knowledge I gained through this video to my near&dear ones. Thanks a lot.
WHO'S THAT POKEMON? :DDDDDDDDD
My laughing must have woken up my sleeping parents xD
Zach, you are amazing! I love when you do this! I am waiting during every single video for you doing some fun. And you almost always do! It makes me sooo happy :)
Thank you for making hard stuff easier
Riddle me this and riddle me that-It doesn’t surprise me SARS CoV 2 comes from a bat.
A very interesting well thought out, laid out and coherently delivered presentation. Excellent!!
I've been watching your lectures since last year. It really helped me during my review for my certification exam! Thank you ❤️
'S'-type is 'L'ess severe, 'L'-type is 'S'evere - lol who came up with this
see "On the origin and continuing evolution of SARS-CoV-2" published in the journal National Science Review
when I saw the 30%...i was hoping for that is the severe one...one more thing to make this scarier
The putative 'L' strain has not been shown to be more 'aggressive' - the finding had nothing to do with disease severity, rather potential fitness. Even this is massively complicated (undermined) by epidemiological effects. The authors retracted the term 'aggressive' soon after publication to prevent just the sort of dissemination of misinformation seen here.
MadMike Foetwenny, thanks for the source material. I’ve been working with an outbreak of 120 confirmed by PCR cases, in a closed community in Texas. All my observations indicate that this virus is not nearly as bad as what I was told to expect. I looked at this data as a possible explanation, but apparently not, as I read through responses to the article to put it in context. It is an ongoing pandemic and I don’t know what the future holds.
God!! Everyone seems to want to out smart the other one....Can Someone just answer his damn question without pretending to be an M.D!!
Mate, it is the most complete video about SARS COVID 2 and COVID 19 I have seen so far. congrats!!
Zach is an amazing teacher. Thank you so much.
You are awesome!!! I am a hospice nurse and you are great at connecting all the dots! Thank you .
Waited for this one... It feels more acceptable when listen and learn from this guy. Thanks
Brilliant man, all this information in his head, no need for note or teleprompte, this is the guy to listen to people! Great presentation!
My 10th time watching this COVID presentation! SO fascinating thank you Zach for being the most engaging teacher ever!
Ninja nerd is my savior. 🙇 thank you
I don't know how you manage to know all the things you do, but please keep up the good work. You're an amazing teacher, and I've learnt so much from your very informative lectures. When we cover new topics, Ninza Nerd is where I go to first. Keep going Champ.
Excellent video dude! Your thoroughness is indisputable and undefeated! I can learn from you for my channel! So glad I promoted your channel in one of my videos!
You guys are awesome, thank you so much for everything you do!
I want to get a shirt! You helped me pass all my science classes and now I am watching to help me pass the TEAS. Thank you so much for sharing all the information you know. You're so smart!
I never finished my undergrad degree, but this video helps put the principles I've learned to use in understanding the virus. Thank you.
Zach is the kind of teacher everyone needs. Waiting eagerly for the vid
Proudly a #NinjaNerd 😊✌
I just want to say you have saved my grade for my finals tests. I’m just sad I discovered your channel so late
Have been following your videos since a year, and I am so grateful for the effort you put on these videos. Thank you so much Zach. Lots of love from Nepal ❤️
Almost 6 months later and this material is spot on.
Thank you very much for your incredible videos, greetings from Germany!
I just discovered your channel. You do such a good job! Thank you. You have gained a loyal fan.
Thank you for sharing your vast knowledge Doctor
Again this is quite an amazing and pure simple compilation of information about Covid-19. I don't think you find it anywhere else. You're a great teacher, you chose and present the content in a super pleasant way.
Thanks for your videos they are as inspiring as informative!
Thank you for making this and presenting the information concisely !
I admire your work.
Can't wait to watch it !!
Zach is very good and clear. All lecturer should be like him.
couldnt find best explanation. Thank you so much
Honestly I would love to see the topics covered in the video as a full transcript marking the references at each point. You cite 111 references in your pages, it's hard to keep up with what comes from which source! It's such a good video, thanks!
Happy to report that I was doing research today and began thinking to myself that I needed a Ninja Nerd Update and surely enough i scrolled down and saw this and nearly choked.
Thank you so much for your hard work!
I’m so excited about this video, you are The best ❤️
!!!!! MAN, YOU ARE TOO GOOD TO BE REAL. YOUR CLASSES ARE TRUE SCIENCE COMUNICATION !!!!!
You are a brilliant illutrators and an excellent teacher, with a flair for simplifying things and explaining medical things clearly, coherently and concisely.
What a teacher , what a channel , you are the best dude truly
Complete chain of information, no bullshit, no conspiracy, pure science. Great Work. Thanks.
Simply the best!!! Thank you!!!!
Excellent. All doctors should have a quick look.
i wish i would live to be a thousand so i could learn all the things you teach. i have a doctorate and certifications and have ceu's all the time (in fact, i'm in the middle of a course right now, so i can't check in as often as i would like.) i know a great teacher when i see one. you are one of a handful of truly gifted teachers that i have ever seen. your command of the subject is , well, let's just say i'm dying. thanks for doing these :)
Zack you are such a great teacher, thanks a lot from Brazil