Types of Receptors: Ligand-Gated, GPCRs, Kinase-Linked & Nuclear Receptors | Pharmacology

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In this lecture, EKG is going to cover the four main types of receptor proteins: Ligand-gated ion channels, G-protein-coupled receptors, Kinase-linked and related receptors, and nuclear receptors. We’ll describe each receptor’s structure and function and identify key examples of drugs that interact with these receptors.
In the previous lecture, we introduced the concept of pharmacodynamics, which is the study of how drugs interact with the body and produce their effects, or simply what the drug does to the body. Receptors are one of the four main types of drug targets.
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Lecture Overview:
0:00 Intro
0:35 Importance Of Receptors
3:01 Ligand-Gated Ion Channels: Structure & Function
6:50 Example - Nicotinic Acetylcholine Receptors
11:31 G-Protein Coupled Receptors: Structure & Function
17:59 Example - B1 Adrenergic Receptors
20:41 Kinase-Linked Receptors: Structure & Function
25:18 Example - Epidermal Growth Factor Receptor (EGFR)
28:28 Nuclear Receptors: Structure & Function
32:43 Example - Mineralocorticoid Receptors (Aldosterone)
35:00 SUMMARY
✏️ All diagrams were made by EKG.
For educational purposes only; NOT medical or other advice.
Lecture Source:
Ritter, J., Flower, R.J., Henderson, G., Yoon Kong Loke and Rang, H.P. (2018). Rang and Dale’s Pharmacology. 9th ed. Endinburgh: Elsevier.
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Thank you so much for this

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u have helped me so much honestly thank u!!!!!!

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