The Story of the Rabies Vaccine
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- Опубліковано 31 тра 2024
- The history of the rabies vaccine is really the story of scientific vaccines at large. In this video, Patrick Kelly tells the story of the history of rabies in society, the origin of the first rabies vaccine, explains the biology of rabies, and tells the story of the four boys from Newark New Jersey that survived rabies.
☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️
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A line-by-line fact checked script can be found here. You don't need to be a Patron to see it. / story-of-rabies-85521605
Rabid by Bill Wasik and Monica Murphy (2012)
www.amazon.com/Rabid-Cultural...
Miracle Cure, the Creation of Antibiotics
www.amazon.com/Miracle-Cure-C...
Rabies Up to Date (UTD access required): www.uptodate.com/contents/ima...
Timeline of Vaccines
historyofvaccines.org/history...
Rhabdoviruses www.ncbi.nlm.nih.gov/books/NB...
Acetylcholine www.ncbi.nlm.nih.gov/books/NB...
Rabies textbook (2003) www.sciencedirect.com/science...
Rabies: a possible explanation for the vampire legend (1998)
pubmed.ncbi.nlm.nih.gov/9748039/
Medical inquiries and observations by Bejamin Rush (1805)
collections.nlm.nih.gov/catal...
America’s first medical breakthrough (1998)
www.jstor.org/stable/2649773
The first live attenuated vaccines (2020)
www.nature.com/articles/d4285...
History of Pasteur Institute
pasteurfoundation.org/about/h...
Lecture 14 - The Germ Theory of Disease
oyc.yale.edu/history/hist-234...
Louis Pasteur, the father of immunology (2012)
www.frontiersin.org/articles/...
CDC’s History of Anthrax
www.cdc.gov/anthrax/basics/an...
Rabid Response (2017)
digitalcommons.macalester.edu...
Inoculation Against Hydrophobia in Popular Science Monthly (1886)
archive.org/details/popularsc...
Louis Pasteur: Between Myth and Reality (2022) pubmed.ncbi.nlm.nih.gov/35454...
Developments in Rabies Vaccines: The Path Traversed from Pasteur to the Modern Era of Immunization (2023)
www.mdpi.com/2076-393X/11/4/756
Four Thousand Years of Concepts Relating to Rabies (2017)
www.mdpi.com/2414-6366/2/2/5
Up to date rabies cases
www.uptodate.com/contents/ima...
Child survivor of rabies in India case repor (2020)
pubmed.ncbi.nlm.nih.gov/32744...
Recovery from Rabies in Man (1976)
www.acpjournals.org/doi/10.73...
Pasteur and rabies: the British connection (1989)
journals.sagepub.com/doi/pdf/...
IMAGES
Pasteur with rabbits: wellcomecollection.org/works/...
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⌛T I M E S T A M P S ⌛
0:00 Intro
0:39 Biology of Rabies
2:58 Hair of the Dog (Antiquity)
8:32 Vaccines al Pasteur (Vaccine Development)
17:27 Out of La Rage (Public Health)
#historyofmedicine #medicalhistory
I am a nurse. Back around year 2000 I was working in an urgent care clinic A patient came in requesting that someone give her the rabies post-bite treatment as she had been bitten by a strange dog. She acquired from the state all needed vaccine supplies but found out that no one locally would administer it to her. Not even the ER. Not wanting to make a long distance trip to our state public health dept., eventually she ended up in our clinic. No one, including myself had ever given it in our entire careers. No other nurse would do it (it was complicated and legal liability was questionable), so I said I would do it after reviewing her materials. The treatment required my study of her materials, doing a little bit of math, and injecting immune globulin around her wound and a calculated dose IM. She also got a rabies vaccine. I forgot all the details but it required a few more visits. I will say it was nothing like the horror stories we have heard about in the past with the injections into the abdomen. It simply wasn't really anything to fear, except finding a person willing to give it which was ridiculous. I found the experience educational and fulfilling and am so glad that I agree to do it.
You're awesome
Good for you for being willing to do it. You may have saved her from a horrifying death, plus you got to learn from a unique experience.
@fredbrandon1645 If one follows the average/typical post-exposure protocol, you need a total of 5 shots. The immune globulin may be given in more than one spot.
Rabies virus vaccine, 4 doses over days 0, 3, 7, and 14, at $510 each, for a total of $2040.
Rabies immune globulin, given by weight and for a person of "average weight" at 70kg/154lb, $4080.
Typical America.
Damn Louis Pasteur. Jabs are experiments. Mengele was number one.
I was bitten by a feral kitten. The ER doctor recommended the rabies vaccines. He said, "Do I think you will get rabies? No. Do I want to take that chance? No." So I did it. It's not so bad. Better than a painful death.
similar thing happened to me when an unfindable cat hissed spit into my eyes.
@@thedacardea416 🙀 did they rinse your eye or anything? I had a puncture wound so they cut it open and cleaned it good so I wouldn't get cat scratch fever. I assume everything went well since you are here. 😹
I met once a friendly fox. It was most likely fed by people so he moved close to me seeking food. I was terrified when it nombled my finger. There was no blood (thankfully) and I think it just mistaken my fingers with sausages or something. Still scary af
@@angelikaskoroszyn8495 did you try feeding it or did you just send it on it's way. Experts say don't feed them but I can't let any person or animal starve. I probably would have fed it unless it looked healthy and well fed. I don't know much about foxes. Are they mean?
that’s so sad. feral kitten. and i had to get it too but because of a raccoon. not rabid but the ER doctor advised it the best idea. what’s important to know is mine was $5k with insurance. i’ve heard of people paying $20k without insurance. and it had to be transported to my facility, not everyone is stocked with rabies vax
I’m rabies vaccinated due to my work (vet med). It is a horrifying disease. I can’t tell you how many people have asked if we can test their animal for rabies…while they’re alive. Yes, ma’am we can test, but it involves removing their head, so you probably want to hold off on that for now.
that's good you are vaccinated, but if you are bitten you still need to get the course of vaccinations.
Are you sure they weren't asking about the FAVN test? I had to have it done for my dog in order to move to Hawaii.
@mother-aiya Nope, you're giving them too much credit lol. When discussing the vaccine, clients opposed to vaccines always ask "well if they get bit, can't we just test for it?"
@@NettiieB yes this is what I actually replied to someone else :)
@@mother-aiya a rabies titer is different. That is testing the antibodies (given through vaccinations) against rabies. An actual rabies test, one that tests for infection, involves removing the head of an animal which can’t be done on alive - or at least leave the animal alive.
I'm a retired physician. I really wish these vids were around while I was in med school. Very few of my professors were such good story tellers.
I heard one historian say that he choose that profession because he was good at telling stories but not clever enough at coming up with them himself, lol.
Historians tend to be good storytellers. It's not a very common skill.
I had a 10 year old feline 2010. One day, he came in. He started to wash the top of his head. He kept washing it. Then next day, the green in his eyes turned brown. He started to do weird things like going on the kitchen counter which he never did. Eating dry food instead of wild smelt. I did a web search and found he had rabbis. I started to think. I figured if I took him to the vet the vet would kill him. Then I remember a Master Herbalist writing about Rabbis being a blood disease. I had the 9 herb combination for blood purifiers. I gave my cat 1 "O" cap a day for 7 days. The second day of treatment he went into recurring fever. On the 8th day he fully recovered. I never heard him purr so loud before. He knew he was ill and he knew I cured him. The blood purifier also cured him from glycol poisoning. He licked up some bate. He started to vomit foam, which is a sign of liver attack. The glycol would then move to the kidneys then death. This only took 2 "O" caps for 2 days. De-worming is 1 "O" cap of: wormwood, cloves and black walnut hulls. 1 cap then 1 cap 3 days later to get at the eggs. Non-calculable price for the de-worming. The blood purifier to kill Rabbis was a few cents.
You have a good point. Sadly, we have all the knowledge of humanity in our hands with our smartphones and portable computers yet we prefer to look at "influencers" and cat/dog videos on the internet. The internet I grew up with is not the internet anymore and governments, corporations and lobbies are trying to control, commercialize and kill any flow of information as we speak.
Humanity might just not deserve it yet I suppose :)
dr sam bailey did a good video about this topic on odysee the website. but everytime I put a link to it here it gets instantly deleted.
@@andrefruth41 sadly YT is very strict about links, especially to outside sites (which is understandable, or the spam bots would be even more annoying). I'm not sure if the "put other symbols instead of dots" workaround method is still viable, but I'd say it is worth a shot!
I genuinely think this was less about ease and more about the pure horror of the disease. It’s turned people mad and frenzied. And it turned our best friends into our worst enemies against their will. And because kids love dogs, it attacked more children. It is possibly the most dreaded disease in all of history.
It's also one of the very few diseases that's virtually 100% fatal, the only effective pre-vaccine treatment was the prompt amputation of the bitten limb, which itself was very dangerous in an era where germ theory was still an open debate. If the bite was to the head or torso you'd just die horribly. I would probably devote a whole bunch of resources to changing that too
Not to mention the best way, or WORSE only way to save a late-stage victim is to mercy them as the silent-pain receptor in the brain are NOT being activated which adds to the fact that this person is AWARE but have no willpower to fight it!!! Whatever rabies came from it is not Terrestrial and WANTS planetary extinction!
@@XSilver_WaterXlol no it's terrestrial
yeah, in pre-Cambrian times, but not times where mammals started to learn to forage?!@@maxwellbarnhart1375
@dianelipson5420 India can send a spaceship to the moon but still has about 20,000 people dying of rabies EACH YEAR! All they need to do is vaccinate all the dogs and there would be far fewer fatalities. But we should not worry too much since they have already outstripped China as the world's most populated country.
My dad was a Marine in the Korean War. Being a dog lover he tried sharing his food with a dog and then got bt by it and they realized it was probably rabid. They had a plane fly to the nearest country that had the vaccine, thankfully making it back in time to save my dad.
Early 50s so does that mean the Marine Corps had to ask around in Japan or India? If the Philippines already had it by then it won't be in a military hospital since most of the best hospitals in Manila had been damaged during WW2. I keep thinking that there were some advanced thinking Navy doc in Japan at the time made sure they had vaccines for everything.
@@miguelladinodevera614 Japan is the nearest country and served as a base for US operations in Korea. Japan probably had the Rabies vaccine even before WW2.
Dayum!!
Can we just appreciate the fact that back then, you can get people together for a demonstration of a vaccine as a public spectacle.
If you want a really wild health discovery/public spectacle look up the Coney Island baby incubators.
now we have the anti covid jab folks making spectacles of themselves on the internet
the difference being that back then vaccines were intensively tested and first demonstrated on animals, then tested on humans, with short and long term effects bing observed and *then* distributed to wider populations.
now they're rolling out vaccines to the masses, within months, with absolutely zero chance of the long term effects having been studied within that short a time frame, with the governments not only allowing this, but also strong arming people (even ones who could easily just get covid and live) into it because i guess preying on fear didn't bring in the desired revenue as quickly as expected.
@@peacenow42 Human Rights are not a spectacle.
it is their right to refuse a vaccine,,,not their right (free of consequences) for trying to recruit folks to join your cause against vaccines. Babies died after that idiot doc said they cause autism. Children here in the USA are behind on their vaccines and pediatricians are afraid it's due to these folks. What about the babies rights? @@edwardsedwards796
My great-grandfather 4 generations back caught this disease in the 1890s. He was a blacksmith that worked close to a school and was bitten by a rabid dog he killed with his hammer (the dog was trying to attack two small school children). After developing symptoms (which happened a little over a month later), the only thing that could be done for him was to tie him to a bed and wait for him to die (he ended up having the furious version). Truly a terrifying disease.
Nobody had the merciful strength to end his suffering quickly??? What a shame. Well that's history. Yikes!
Rabies is not uncommon though today in less developed areas of the world.
at least he died a hero. what a horrible way to go.
@@Starry_Night_Sky7455You're not a very intelligent person, are you...
He was a Hero!!!
@@SludgeManComethyou wouldn’t want to be put out of your misery? shit i would
I actually recently got a bat bite last month (may). Went through the whole round of vaccines. Along with a tetanus shot my arms are still aching with phantom pains.
How did you get bit by a Bat?
@johnnylego807 I poked it. He or she was hanging out and I poked them to see if they will fly off. He squeaked and bit my thumb. I remembered that moment he bit me of: "Oh shit rabies"
@@mariawhite7337 Wow!! That’s scary as heck, where did you poke it? Was it in a tree or cave or house? Hope your feeling better 💪
@johnnylego807 I'm mostly better and it was where I work. 😆 the phantom pains at least only seem to trigger when I'm anxious.
You tormented a tiny animal. Kind of had it coming, @@mariawhite7337
I wanted to find out if rabid people bit others so I started researching it.
That sent me down a crazy rabbit hole. Rabies is a horrible, horrible illness.
The answer- rabid people dont generally bite people. They can get aggressive and hit people though. Rabid very young kids might bite though.
Makes sense, many animals bite as a defense but humans don't really.
Or in this case
A crazy rabid hole
clearly you never seen a baby who bites...mine did from age 8 months to about 2 whenever any child got near him.@@Flippityfloop44
It's a crazy rabbit hole, but not crazy to wonder about it. Makes me think about anxiety over people spreading rabies to other people and possible connection to legends about vampirism and lycanthropy.
makes me think of the grown adults not only refusing the covid jab but publicly declaring so, while children are the ones who did take the risks of the rabies vaccine first. And chemo...and gene therapy@@douglassun8456
People love to imagine a "zombie virus", and although reanimated corpses that can spread their undeath through bites may not be realistic, rabies is pretty similar to what we would expect a "zombie virus" to be. Its both horrifying and fascinating to learn about, and im glad i live in an age with an available vaccine. A big thanks to everyone who put any effort into getting us that far, especially pasteur.
I find it really funny that vampires, werewolves, and zombies all likely were inspired by rabies.
Covid was a world wide event literally stopped the entire planet during this great awakening and barely anyone is waking up meaning the zombie virus hot them. When you eat rotting animal carcass aka meat infested with maggots and worms and rabies it tends to eat your brain which is why very few are waking up. There's the awakened and the woke. The fact they're dead and don't know they're dead is not something to wish on anyone. When something like this happens God sends plagues, famine, war, death. The four angels and horseman are for when everything gets out of control God sends a contagion to stop the virus. They're cannibals now you can't come back from brain dead they're eating their own children killing themselves off (abortions and HEK293) MK ultra mind control technology is to keep them under control until the four angels and horseman show up. 5G keeps them asleep eating flesh keeps them asleep. This is what everyones wars have created a bunch of dead people that don't know they're dead. Fascinating until it's happening to your family.
@blackosprey2219 well zombies were originally a cultural tradition thing and were probably just people who didn't actually die but wound up with severe brain damage after the "ritual".
@@minacapella8319 Which ritual? There's so many. Everything was settled up so if anyone cursed another they would be cursed. If they put a spell on someone it would happen to them. If they cheated they would be cheated. If they stole they would be stolen from. If they invaded they would be invaded. Occams razor. For instance if someone does witchcraft hoodoo voodoo dark magic necromancy on someone they need their verbal consent handshake looking into their eyes conscious subconscious interdimensional and unconscious consent otherwise it only effects them if they don't have consent. Rules of magic don't do anything that could come back and backfire upon them. If someone cursed someones land and bloodline it ends up cursing their land and bloodline. Making it a moot point if they don't have consent in every realm timeline and dimension. Someone can vast the darkest magic on someone but if they didn't give them permission it's doing nothing but backfiring on them. Universal law karmic law. Smoke in mirrors. Someone could think it's someone else they're attacking with the hall of mirrors but it could actually be them on the other side they're putting spells on. Keeps one humble truthful and obedient to the ten commandments knowing everything could backfire.
@@minacapella8319I heard it was from the voodoo culture. The witch doctors have a poison made from puffer fish which at the right dosage can induce a dead like state. It's well known that there have been cases of puffer fish poisoning where people came back to life after their hearts stopped.
When I was a kid I was going outside to play when my mother snatched me back in the house and slammed the door. She said, that dog has rabies!
I looked out and there was a poor old dog standing in the street tossing his head side to side and thick strands of salvia was flying through the air. He was growling and shaking and it looked terrifying to me.
My mom called the police and soon a cop came and parked near the dog, he got out and carefully got close enough to shoot the dog in the head. I was about 6 years old and the experience never left my mind.
I had the rabies vaccines back in the 50’s. 14 shots in the belly. I was about 6 years old. Our dog scratched or buy a neighborhood kid. His/her mom asked my dad to lock the dog up. It died over night and had a foamy substance coming out of its mouth. Everyone that had came in contact with us or the dog had to get the shot. It was an event for sure as the line stretched around the block where the local Dr’s office was. The nurses would use tattoos of Popeye, Olive Oil and Brutus on our stomach so that ‘ they’ would get the shot.
being the 50's those tattoos were probably made out of asbestos and uranium :D
@@metralla no. They came with bubble gum. Wet, place on arm and pull off
@@davidvines6498 and glowed in the dark :)
dr sam bailey did a good video about this topic on odysee the website. but everytime I put a link to it here it gets instantly deleted.
@@andrefruth41 well, what was the video about
I’m a health inspector in Ontario Canada and we investigate animal exposures due to the risk of rabies. The cost for rabies treatment is covered by the government and public health keeps the vaccine and dispenses it when needed. Saw some comments where people need to pay 10k+ out of pocket in the States, which is insane!
Please don’t come here. Terrible healthcare, corrupt politicians, tyrannical cops, abusive incarceration system. Please, for your sake please don’t come
Yeah, no. $400 is about what a dose of human rabies vaccine costs. That isn’t even in the ballpark of $10,000 even in worth less Canadian dollars.
@@ViperPain141 US healthcare is great.
if you can afford it.
@@Reverend_Salemjust costs an arm and a leg to save your arm and leg 🙄
Untreated rabies having a 100% mortality rate is insane to think about. Ebola is like a 50/50 chance. Although Ebola does sound like a more painful death.
Diseases suck.
Rabies is found nearly everywhere, ebola requires more of its environment I guess.
Nah, having your brain slowly swell while you die of thirst, knowing that there's nothing you can do while you choke on your own saliva has to be worse than ebola. Bleeding out is bad but at least you have some amount of hope. You have no hope with rabies.
rabies is a hoax, never been isolated.
@@Will_Parkerunless you take the vaccine
Creutzfeldt-Jakob Disease is practically worse. No treatment, no cure.
There was a toddler patient in northern california around 15 years ago who also survived and it was the region's first successful treatment of rabies, they worked really hard because she was a child. It left a big impression on the community.
Is this true? I thought it was incurable post symptoms. I’d be curious to learn about the case
But at what cost? Don't usually survivors of rabies have permanent brain damage?
@@Belenus3080there are several cases of survival. One of the best documented cases led to development of the Milwaukee Protocol. There are multiple videos available about the treatment and the patient.
@@Belenus3080there are several cases of survival. One of the best documented cases led to development of the Milwaukee Protocol. There are multiple videos available about the treatment and the patient.
Oh yeah, also she never received the rabies vaccine, so is also the first documented case of someone surviving without it.
It does actually somewhat cause a fear of water because even just seeing the water while that dehydrated causes an involuntary swallow, which then results in incredibly painful spasms.
So you show them a cup of water and they'll react like they're being strangled. At least in some cases.
I'm so happy birth control is a popular choice.
@@Starry_Night_Sky7455 which is kinda ironic given that someone let you survive
@@TacticalTerry😂😂. no bc what was the reason for saying that? what was the relevance?!
@@waner17 Starry's comment was kinda off topic, but the more I thought about it the more I was interested in that line of thought.
"I am glad that there is something that prevents people from being alive by limiting the population" seems to exclude the thought that this was a process that was not applied to them. It takes life for granted on a very simple and limited level. Not a judgement on Starry, just an open-ended observation.
Has nothing to do with rabies at all :0
@@TacticalTerry why not limit the 0.00000001% that use 99% the resources? what good reducing population of 99% that own 1%?!?!?
In middle school we were taught that Pasteur discovered pasteurization by boiling milk to kill bacteria, and then used a similar process to create the rabies virus vaccine. My teacher skipped over all the rabbit brain and, you know, all of the actual experimentation stuff, and went straight to the treating of the first boy being an immediate and mostly private success as opposed to the highly publicized and high-stakes case that it was. The real story was in the curriculum, but she deliberately skipped over all of it because she didn’t feel like actually teaching us about how vaccination works
And that is one of the reasons we deal with people who think vaccines are a "scam" or any number of other baseless theories. If more people understood how vaccines worked we'd be better off.
@@strayiggytv the covid shot is not a true vaccine its gene therapy so yes it is a scam.
@strayiggytv welll then you have those who do take a vaccine and still dont understand how they work... you should take a vaccine if you need one and only if you need it.. natural immunity is the best way to fight off viruses but sometimes our immune system isnt strong enough and would benefit from a shot. But once you take the shot youll have to keep getting it bec if you dont youll be so sick youll regret not getting one. Your body now depends on the shot to protect itsself.I havnt had any sort of vaccine in 20 years and still get sick less then everyone around me. Could even be around sick people without getting sick! And the only way to get sick is from an immune system overload.. feels pointless to even type this but just wanted to educate those who will tell people to take a vaccine.. some or even most of us plain out dont need any kind of shot and can fight most viruses off by our own immune system.. so take a shot if your prone to getting sick or have a weak immune system but dont belittle people who refuse to take one,when knowing damn well they dont need one!!
Which is why people think vaccines cause autism. Not enough education.
Ikr, but thinking about it my dumb 13 years old self won't understand it anyway
people in 1800: give me the experimental vaccine
people in 2020: vaccines are bad
People in 1800: lets experiment
People in 2020: with the number of steps in modern medicine that were skipped in order to get this vaccine out, I’d prefer not to be the experiment of this vaccine specifically
@@ItzzzBeamoSeems to me the rabies vaccine skipped a whole lot more steps than the covid vax.
@@ItzzzBeamoyou’re forgetting that antivaxxers also won’t get *any* vaccine, not just the covid vaccine
@@ItzzzBeamo vaccine bad. Take horse medicine and bleach
@@ItzzzBeamo hardly, these vaccines are based in evidence which you ignore, so remove yourself
Back in 1991, only about 100 years after Pasteur's vaccine, my brother was a state health inspector in south Florida. He told me how he personally was the one who had to take the rabid dog's head to the lab to be confirmed after a dog bite.
That's bad ass imo
@@AdaptiveApeHybrid He saw a lot as a Miami health inspector.
@@betsybarnicle8016 sounds kinda exciting to me. Potentially fulfilling as well
Risky work from an infection point of view. It's good that your brother didnt contract rabies while handling the dogs' remains, was he vaccinated? I assume it was mandatory for your brother to shoot the dog, whether or not it appeared to have rabies symptoms? I wonder if automatic euthanasia would also be carried out if a human got bitten by an individual of certain wild animal species in North America which harbour rabies. I know that in my country Australia, rabies is current only in some of our bat populations. Wildlife rescuers and vet staff who are vaccinated against rabies are the only people permitted to handle bats in Australia. If an unvaccinated person is bitten by a bat, (usually while trying to handle a bat that is injured) the bat has to be euthanased at once, and its brain dissected to check for the presence of Lyssavirus. Luckily for the person bitten, I believe there is an course of injections which is very effective if started early enough.
I’ve been there myself plenty of times; one time I had to help dig up a recently dead dog!
If you think about it, a lot of the various humans-to-monsters myths involve being bitten by the monster. Rabies is probably an inspiration for many of them all around the world.
Totally. The book I recommended, Rabid, goes into depth on the cultural impact of rabies. It's a great book!
Fun linguistic fact: In Slovenia, we call rabies "steklina"
Sort of a derivative from the word "steklo" or in english "glass". That's because when a dog/person gets rabies their eyes get "glassy". It's interesting how two language groups focused on different aspects of a disease, resulting in a different naming.
Not everywhere. We in Croatia call it "Bjesnoća" which literally translates to something like "rage disease".
@@Marijanus thanks for making me actually look up what Slavic means. I thought Slavic and Slovenian are the same thing, but apparantly not. 😅 I corrected my mistake.
@@MarijanusSame in Bulgaria, we call it "Byas", which just means "rage".
This certainly allayed a lot of my rabies anxiety. Thanks a bunch!
We've come full circle! Thanks for watching
@@PatKellyTeaches, have you done a video about tetanus? If you aren't vaccinated and contract it, it's life-threatening. My wife, a nurse, once had a patient who contracted tetanus from digging in her garden and spent months in a medically induced cima; tge woman lived but suffered permanent neurological deficits.
This convinced me to watch the rest of the video. Thanks!
I'd love to know what was used on the ones who survived
dr sam bailey did a good video about this topic on odysee the website. but everytime I put a link to it here it gets instantly deleted.
Rabies is not 100% mortality rate. It is 99.9%. There was a small group in Peru who had rabies antibodies but were never vaccinated (meaning they survived rabies). There were also a handful who survived it outside of that group.
Yes, I mention that towards the end of the video
I wonder what kind of long term effects occur if you naturally resolve rabies, if any.
@@FreejackVesa Outside of the group in central/south America, I have only heard of a couple survivors, and they had serious affects because the only way they beat the virus was changing the body temp, as the rabies virus needs warmer temperatures of most mammals. Which is why opossum are all but immune. They are cooler than most other mammals.
@@williamstandish2926 interesting, thanks.
@@williamstandish2926how did they change their body temp?
As a fun fact, Alexander Yersin, the man who helped discover the plague virus, lived in Vietnam, in the coastal city of Nha Trang where I currently am . His house and laboratory is now a museum you can visit.
Yersinia pestis is a bacteria
Pasteur seems to be underrated. That man really brought humans ahead incredibly in the medical field. A pure genius. I wonder how long humans would've needed to gain all the knowledge we got from his work.
Put his name on a car license plate. I mean why not? PASTEUR is 7 characters and maybe its free to use.
Hes one of the only scientists I remember by name from elementary school lol
Pasteur is a criminal. He killed many people.
Pasteur noticed that fewer women were dying after childbirth, but this applied only only to midwives (females) *who washed their hands, while male doctors didn't.* He only gets credit for noticing.
Maybe. But you do find his name in the dairy case of every market. That's something.
I’m a horse and dog trainer in Alaska. I had gotten a mostly feral dog from one of the Western villages. I quarantined him, which I was not required to do. After three months of good progress, and no suspicious symptoms, one afternoon he mauled me inside his kennel. It was pretty horrifying. He was so fast and SO strong. 12 minutes felt like a decade. I won. I got out, and he didn’t. I had 51 punctures (14 into the bone or joint) in my arms and hands. The most heartbreaking part was that there would be calm moments, and that sweet dog was inside, and scared to death. Yes, the scars burn from time to time
Interesting video, I do have to say it is possible to get rabies without being bitten. Any bodily fluid can transmit it, by rubbing eyes, contact with the mouth or a cut however small. It might be rare but since rabies is fatal once symptomatic people should be aware and careful about touching face etc when handling unvaccinated animals or their bowls.
Absolutely spot on! Thanks for your comment.
There "bowls"? sure people will be holding the internal organs of the animals. no definitely not
@DankNoodles420 you're thinking of bowels not bowls.
@@ThemanlymanStan the person I replied to had put bowls lmao
I saw a documentary some years ago in which they put a rabbit in a cave with rabid bats. The rabbit was protected by a metal screen and the rabbit contracted rabies without bitten or scratched.
The fear of dogs I have observed in some immigrants makes so much more sense after watching this video, and I have never felt like a bigger asshole for being amused by the response.
Also, a lot of European/Asian cities have a massive problem with stray animals and very few resources dedicated to controlling it in many places. Vietnam and India come to mind immediately, as do many middle eastern countries. All it takes is one rabid animal...factor in also that a lot of places don't have the vaccine readily available or only in limited supply (ie India with its massive population and also its feral dog problem is some areas...)
Oh wow that's why my Iraqi colleague is scared of dogs... I always wondered but never actually asked!
Had a lot of Pakistanis here in england and when I took my dog for a walk they were litrally terrified
@@davehoward22 my Pakistani in-laws are who I was thinking about when I made that comment, though I have observed the fear in other South Asians and Muslim immigrants. Now I try to carry my dog's or give plenty of space if I am passing anyone who looks like they might be made anxious by them.
@@Kitsune1989as an italian this is facts lmao you dont ever feed them strays either unless you wanna see the whole animal population the next morning 🤣🤣
Thks, &;
I had it , got the shots, barely survived, took a decade to recovery my health, & got verry lucky.
How did you get it?
As a baby boomer, I am amazed at how much progress has been made in medicine not only in my lifetime but the few decades prior.
I would also like to know more about the anthrax vaccine! One of my cousins works in a laboratory with it and had to be vaccinated for it, and it was a GNARLY process (very painful and relatively short lasting).
I've got a draft of that script ready! Hopefully I'll get it out early next year. The antibiotics series is taking all my attention right now 😵💫
RIP all the poor animals who have contributed to a healthier human society.
yeah that part was really tough to listen to, poor bunnies 😔
Time to do better
And healthier animals, too.
@@Fido-vm9zi We can't.
I agree that testing cosmetics and other crap on animals is stupid, but when it comes to drugs, we have no choice, they have to be tested, unless people volunteer.
The procedures for avoiding animal testing are already very advanced, with months of waiting to judge whether it's justifiable to use animals or not. We already do our utmost to avoid using animals whenever possible.
@@Petitmoi74 figure it out on an ai system
My Dad's brother died from Rabies when he 3 years old, around 1916. No one had any idea where the little guy was buried. His body was spirited away and disposed of. Live with that Grandma. So sad.
I feel like Ive earned one biology credit from paying attention to this!! 🏆👩🎓
It's more of a history piece
@@Starry_Night_Sky7455 TWO CREDITS IT IS, THEN! 😂 We all get 2 credits
I'm surprised this channel doesn't have at least 1M subs, the quality of the editing and research of this video are so good.
I appreciate that! More videos coming soon
@@PatKellyTeaches It was apparent how little many people understand vaccines from the reaction to the COVID Virus vaccines. Are you willing to tackle this very unnecessarily controversial topic?
He isn't a big boob Kardashian.
I just discovered this video, now big fan of the channel
@@vernonfrance2974 These new mRNA vaccines aren't based on the same technology as traditional vaccines. It's effectively a gene therapy, and we're right to be cautious.
I recently completed my rabies series after coming into contact with an infected bat. The shots were no big deal at all, no worse than a tetanus shot. Amazing stuff, theres only been one death in my state since the 50s and it was an individual who was unknowingly exposed and was symptomatic before getting to a doctor.
Absolutely top notch! Subbed.
I recently saw a video of a boy in India in the late stages of hydrophobia and it was heartbreaking.
Thank you for mentioning the oral vaccine, which most people - including most vets to whom I have spoken - are unaware. I think that this vaccine does provide a possibility of eradication of rabies; we just have to figure out how to bait it properly.
It is a travesty and a heinous offense that your channel is underrated. The fact that your videos are this well produced, narrated, and researched and for you to just have a couple thousand subs?? A crime. Really. Easily one of my favorite channels now.
It takes time. I found this video by accident. It's hard to market on UA-cam, I think. It's a shame. Maybe if he added a cute cat. 🤷🏻♀️
UA-cam algorithms apparently recommend and select videos based partly on the video creators' friendliness to advertising. If the creator allows ads before, after and especially during the middle of the video, it's more likely to be promoted by the algorithm.
Relax dude, it just takes time. Like your happy pills take time to kick in, apparently.
@@Joy-TheLazyCatLadyMainecoon or Bombay? Those are my favorite cat breeds.
@@princesspikachu3915 oh yes. Both beautiful breeds. Norwegian Forest Cat is also beautiful. I just have domestic rescues. One black and one tortie.
This was an awesome video man. I was just studying Rabies in Microbiology and you uploaded this video today, great coincidence. Learned a lot about the history of this disease. Keep up the good work🤘
I appreciate it! And that sounds like a fascinating microbio class
The "Rabid" book referenced here is an especially good read. I also recommend "The American Plague", about Yellow Fever, and "Black Death at the Golden Gate", about bubonic plague in America (accidentally imported from China in the late 1800s but now endemic to rodents in the Southwest).
The one that really worries me is Hantavirus, also endemic to rodents in the Southwest but likely to spread along with climate change. There was a case in Long Island NY a while ago. Tickborne illnesses are also spreading....
Very cool but it didn't answer the big question. Why is the rabies vaccine so cheap that every dog gets it but so expensive that humans only get it when the really need it and then at enormous cost?
American healthcare???
@@TheAmazingEevee🎯
Because humans are at a much lower risk *because* the dogs are vaccinated. It's like why they don't vaccinate agaist smallpox anymore and if you need it it's near impossible to find in the US and expensive. Humans and dogs obviously have different vaccines, so fewer human vaccines are produced, making it more expensive and in higher demand.
India is the producer of vaccines for the world.
There was recently a case in my city - the boy was bit by a dog - he out of fear did not tell his parents.
looks like the parents were too strict .
That boy died in his fathers arm & the whole thing was captured on camera.-whoever saw it cried a bit .
This whole incident sheds a fresh light into what awareness is needed from an early age in all countries alike.
Your video was great - .
With that many people in the country alone, is there an efficient and effective vaccination program for all Indian citizens? That story btw is quite similar to something that had happened in the Philippines years ago but the teen victim was already far gone and his family had to ask dispensation from the local Catholic priest for mercy killing. Ofc the Church said no and the family were so grief-stricken to the point they actually asked the asylum where the boy had been admitted in to just end the boy. When the young man died, his body had to be cremated. Rabies is quite uncommon in the Philippines over the years and thankfully most adults r always careful when it comes to stray animals.
Fleshlight?
We need a lot more health education. The COVID showed all the defficiencies and corruption didn't help either.
Tbh I think we need more researchers they are the real people who cure people not doctors
I’ve had the rabies series twice. Once in 1960 (my dog acquired rabies from a second vaccination within 7 months - travel requirement) and once in 1995. I asked the second doc why there was so much pr in the 50’s about “the horrible rabies shots when they weren’t that awful. He said they didn’t want lots of people getting the shots because of the serious side effects from growing the vaccine in eggs - not because of painful injections.. that may explain why the nurses didn’t want to give them. A little truth would have helped…
Jeez! How utterly ridiculous. When I was a kid in the ‘50’s, I saw a tv show about how it hurt so much. I really do not understand or trust the medical field about some things. Always search for a knowledgeable medical person, people. They are out there. :) 🌷
I had to get 4 rounds of rabies shots over 3 weeks, about a month ago...it was brutal! I got sooo sick! The first round with the IGG shots was definitely the worst. But better safe than sorry of course...as bad as it was.. rabies is far worse.
I was bitten by a bat that got into my house and I didn't know I was supposed to keep the bat for testing and just wanted to get it outside as fast as possible. 😖
I live in a small town and was the first person to get the rabies shots in the ER since it was built 10 years prior. 😬. I also had our public health office visit and called to make sure I made all my follow up appts. It was surreal.
Vaccines “al pasteur” is funny. Well done 😂 now I’m craving tacos 🍍
I had to get rabies shots around 2015-2016 when i was 11 because I held a rabid bat that fell in our pool lmao super surreal looking back on it
After a dog bite my father received a shot just to be safe
A friend of mine did the same after a recent suspected bat bite. It's still out there!
@@PatKellyTeachesA former neighbor used to feed the raccoons. After I narrowly escaped a frothing-at-the-mouth raccoon, I called the DEC (Department of Environmental Conservation). The guy there told me that the mother raccoon could incubate the kits she was carrying for nine months, who would then be born with full-blown rabies.
It is a very clever disease.
SCENE: it is the year 1880 and LOUIS PASTEUR walks into a RABID DOG STORE.
I recently learned that there are cases of rabies laying dormant for 7-25 yrs before killing it’s host
This is so engaging, well made and informed! I'm an immunology student in the middle of my last virology unit for my undergrad degree and it's all been so humbling to learn. In countries where the largest disease burden is primarily genetics and lifestyle-mediated illness (and increasingly drug resistant microbes), we've become complacent about our very recent horrific histories with infectious diseases. People in developped countries don't often see or know of the burden of such infections, although the pandemic has provided some awareness (for better or worse).
You're just a complicated meat sack! Don't take your innate and adaptive defenses for granted, they do so much. Vaccines are vital.
Complicated meat sacks! Unite!
If one of these "anti-vaxxer" folks gets bit by a rabid animal, do you think they'd stick to their anti-science ideology or do you think they'd get the rabies vaccine ?
By definition they would stick to it and face death
Covid shot is not a vaccine it's gene therapy. It was marketed as a vaccine so the Pro vaxxers would line up like sheep.
Sushruta is considered the "Father of Plastic Surgery." He lived in India sometime between 1000 and 800 BC, and is responsible for the advancement of medicine in ancient India.❤❤
As a Customs Officer in the UK we were given rabies vaccines as well as Hep B for years.
Brothels for dogs? Guess that might explain where they were playing poker.
I named my golden retriever Lyssa. Funny that pretty much only the vets office gets the joke.
That's morbid and I love it
My neighbor still feeds racoons like they are house pets. Really pisses me off to see someone doing stupid stuff like that.
I do it for possums they’re chill
There this UA-cam that has hundreds of racoon
S😊
What I find really interesting about this period of medicine is how scientists were able to develop actually effective cures despite lacking many of the theories that underpin modern medicine solely through rigorous and consistent application of the scientific method. Like this is before the modern atomic model and quantum physics which underpins modern chemistry and is what explains almost all chemical, and thereby biological, interactions. Like we didn't know that cell membranes were made out of phospholipids or that cells control what passes through it with proteins that fold based on polarized molecules, and we didn't know that viruses will try to hijack some of that protein machinery to get inside a cell and infect it. We also didn't know that the way the immune system identifies disease is with messenger proteins on the surface of every single human cell, and that a large part of it's defenses are based solely around proteins. But the beauty of the scientific method is that it is able to solve problems even if you don't fully understand the underlying issue and often in doing so you gain a greater understanding of the problem. It's a great illustration of why science has been so successful, because it's a method that will always incrementally lead you close to the solution no matter what so long as you stick to it.
Well said.
Glad I'm not the only one who finds this fascinating. It's amazing how with such little information on disease and how it functions and spreads we were able to determine a functional method to solving the problem
It's criminal to call this process, 'anecdotal', and further criminalize doctors who used this process for cvd19. Pure evil is the only explanation.
You will be surprised how much u can get down with alot of missing information if u have the drive you can do it this is the reason why alot of cures are not being made today because now of days people want to be doctors or other things and not the main thing that help make cures doctors don't make cures they just diagnose people and based on that find the correct steps but I think now of days we lack good researchers and also goof researches that aren't afraid to try and try over again until they find a curw
Quantum physics, lol. This man is a freshman biology student at Dunning/Kruger University.
I just discovered this amazing channel yesterday. I just don't understand why it's not so much more popular!
Interestingly, rabies in horses results in the classic "furious" disease less often in other animals. Horses get vaccinated usually, but if they do get rabies it'll present (often) as "weird neurological symptoms" that are easy to mistake for something else.
Anyway, this is a really cool story and I'm grateful to Pasteur et al, because I've had a course of rabies shots myself! Thank y'all for making sure I wouldn't die of a dog bite.
i teared up from this one :,))) as a scientist i think its so beautiful how far weve come through bold and faithful strides towards discovery!
5.200…in 2019. Wow! Thanks for the video, good stuff as always.
My 4yo's favorite book, to be read every night, was this wonderful story of a little boy who was saved by penicillin.
So well written AND he shows the primary sources! You sir deserve at least 500K subscribers. I have subscribed and am now going to binge watch and upvote the rest of your videos. Please support creator's that know the scientific method.
"I'll take 2 packs of smokes, 1 bottle of wine, and some rabid dogs, please."
Incredible video as always, Patrick! Can't believe how comprehensive and well-researched this was (not to mention the production quality!).
The Thai word for rabies is "Gua Nam", which translates as fear of water....one of the symptoms. I saw 2 rabid dogs try to attack kids and then a crocodile. The crocodile ended their misery. Its a scary illness indeed.
😮
Excellent, I found it most interesting where it was described so well in Mesopotamia.
I've gotta double down on my recommendation for Rabid then! Great book that goes into even more depth on ancient history
@@PatKellyTeachesComfortable entertainment when you're reading 📚 this, not experiencing it.
Thank the algorithm God’s for smiling upon me! I LOVE THIS CHANNEL! SUBSCRIBED
This certainly allayed a lot of my rabies anxiety. Thanks a bunch!. This certainly allayed a lot of my rabies anxiety. Thanks a bunch!.
I am a virology student from India. Loved your video. So concise
Brilliant video. Just brilliant. Interesting, informative, engaging. Bravo.
This is so cool and fascinating. Pasteur was a brilliant thinker
I just read Wasik and Murphy’s book, “Rabid”. 👍🏻👍🏻
Excellent description of the disease process in humans, and how it’s one of the few viruses that travel along the nervous system.
They go into great detail also about Pasteur’s experiences with vaccines. as well. Very readable!!
I used to work in a facility that produces many different vaccines, including rabies and anthrax. It also produces factor VIII. It was very interesting to learn how those things are produced
One of the craziest things I’m this video is the casual mention of serial passaging rabies in the rabbits and creating a super rabies that had a faster incubation and a higher infection rate in the 1800s 😂😂 good thing that didn’t get out of control.
Literally was about to say that
This was an incredibly entertaining way to learn about Rabies and Vaccines in general. Thank you for your work!
I appreciate the kind words. I'd love to do the diphtheria antitoxin next. Such a unique story
fascinating video, will definitely check out the rest of your channel! really appreciate the captions too! have a great day :)
Those ancient remedies and theories are so crazy and...creative!
I'm a simple person. I see someone talking about infectious diseases, I subscribe.
You are gonna love the rest of my channel then 😜
@@PatKellyTeaches I /might/ have already binge watched about 1/3 of your videos already.... and by /might/ I mean I totally did.
And then spent an hour rambling to my husband about infectious diseases again....
I remember watching a documentary on the Milwaukee Protocol- a teenage girl who had already began showing neurological symptoms of rabies weeks after a bat bite. This was about 15 years ago but they shut down her brain by inducing a coma to give her immune system time to catch up. I don't know if the timing was just right or if it "confused" the virus since it didn't have a functional nervous system or brain to replicate in.
They brought her out of it a couple weeks later since her body fought off the infection but she had to relearn everything. Talking, walking, eating, etc. And to my knowledge that protocol hasn't been successful since.
You did a great job telling this story. The pace and organization was perfect for such a large amount of info. Seems like you did a lot of research as well. Ty!
Thank you for the kind words, I appreciate that!
I had 50 rabies shots around 1961. I survived. I remember the entire ordeal.
@@buffys3477 I learned what a vaccination was at the ripe old age of three years old and it was my own pet dog that bit me.
Incredible video as always very well done
Thank you so much for that warning about animals! Very appreciated.
Thanks Bro. You are amazing for providing such a detailed report. 🙏
Great video !
I got bitten by a bat while sleeping back in January, didn't realize it was a bat bite until March (that's a whole other story). So I went to my doctor thinking I'm probably just over reacting, there's no way it was a bat bite, but he actually took pictures of the bite on my arm to consult a colleague. An hour later he calls me and tells me to go to the ER next door as soon as possible and get the vaccine. Craziest emotional rollercoaster I'd ever been on, but getting treated settled my nerves. Rabies is a huge fear of mine so this experience was like living my nightmare.
I got 4 shots on day 0, then one on day 3, day 7, and lastly on day 14.
Oh also it costs $12,000 to get vaccinated for rabies through an emergency department in case anyone was curious.
Same happened to me last month, but I don't actually know if I was bitten since I was asleep and had no visible bite (which they say you cant always see with bats). Insurance paid for my shots 100%, man that sucks if someone goes into medical debt over those shots 😕
@@oprin10 luckily I have a FHA card to pay it little by little each month but yeah seeing that bill made my heart drop through my butt. It is what it is though, at least I don't have rabies 🤷
Very cool and interesting presentation! Really enjoyed it. Thank you!
Thank you for what is an absolutely brilliant video… very, very interesting, really well-presented and researched and so fascinating. Can’t wait to see more of your work, so will subscribe immediately and tell all my friends!
the problem with countries like india is that people are very poorly educated about rabies, they know what's up when a dog "goes crazy" but they handle it way too nonchalantly.
india has a problem w misinfo about rabies, a person bitten by a rabid dog will be told its "puppy pregnancy syndrome" and to avoid getting rabies treatment bc it will make the witchdoctors "treatment" not work. its not just a matter of not caring its ppl being lied to by scammers
What an amazing video. Well done !
Subbed.
👍🏻🇨🇦
This is my first video for your channel and I absolutely love it. I already subscribed. I absolutely love medical history. I did not even know that the plug vaccine came out that long ago I would be totally up for seeing a video about it
So happy to have found this channel. Your videos are so interesting!
Thank you for the sensitivity warning! 👍
I whole heartedly appreciate the TW/skip ahead recommendation for people sensitive to animal mistreatment ❤
Underrated channel, very good content and presentation
Put Rabid on hold at my library, thanks for the rec!
It's so good. One of my go-to popular science books to recommend
Great video, you deserve way more subscribers and views! Keep up the good work, I know you're going to blow up one day, subscribed! 👍