Active Surveillance for Gleason 7 Prostate Cancer with Minhaj Siddiqui, MD [EP 70]

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  • Опубліковано 10 січ 2025

КОМЕНТАРІ • 63

  • @RealRocdad
    @RealRocdad Рік тому +22

    Went to doc for possibly low Testosterone, 66 WM good health lean body, doc did PSA along with T, T was 550, PSA was > 600, month later >900, last one >1550 j just had biopsy Gleason 7 in mostly left quad, prior CT suspect for metastatic. Urologist said no surgery or radiation too late, possibly Chemotherapy. Currently creating my own protocol starting with Full Spectrum RSO, Curcumin(w/oil & pepper), high oral vit C (search 4 IV), multiple blends of others, mushrooms etc. Started Fenbendazole 444 mg daily no breaks... Limited dairy, gluten & sugar as possible, threw away Calcium & Iron supplements today. I will beat this.

    • @DrGeoProstatePodcast
      @DrGeoProstatePodcast  Рік тому +6

      Thanks for the comment but sorry to hear about your situation. I think you should consider guidance from an integrative oncology professional. OncAnp (google it) can help you find a good practitioner. All the best.

    • @RealRocdad
      @RealRocdad Рік тому +3

      @@DrGeoProstatePodcast yes I have problems with my urologist already I'll be firing him...

    • @Drnardinov
      @Drnardinov Рік тому +2

      Good job for hitting it with a plan. Just watch out for your kidneys cuz I started doing a ton of supplements and my kidneys took a beating. It may have been the apricot seeds. Don’t eat more than a couple or 3 a day. Good luck and let us know how ur doing.

    • @RealRocdad
      @RealRocdad Рік тому +7

      I took a PSA test 2 months ago and my PSA had dropped 1250 points, took one last week and it was up 180, I blame myself for faltering from my plan and letting myself run out of RSO and not taking my FenBen consistently when I didn't feel good a month ago, currently I feel really good bone pain is gone and also I have confirmed at least for me that Cialis 5 mg a day is much better than Flomax and it fights cancer.

    • @schmingusss
      @schmingusss 15 днів тому

      @@RealRocdad Fenben reduced your psa? What is your psa at now?

  • @bigdaddy5948
    @bigdaddy5948 Рік тому +9

    Anxiety is part of any cancer diagnosis. It seems developing a positive attitude to fight the issue is imperative. Age. Life expectations. Quality of life. It's a very tough place to be in.

  • @Jack-2day
    @Jack-2day Рік тому +15

    Dr Geo, as a Gleason 7 (3+4) I really appreciated this interview. Absorbed some insightful information. A friendly request though, if you could sometimes allow the highly knowledgeable Dr you have brought on board to finish his thoughts. (We tend to find ourselves sitting on the edge of our seats to the great questions you have asked...)🙏 Again thanks!

    • @iconoclast6994
      @iconoclast6994 5 місяців тому +5

      Yes. Dr. Geo, please allow the guests to finish thoughts without interruption.

    • @axcab3437
      @axcab3437 4 місяці тому +3

      Agree.

    • @EBridgeman
      @EBridgeman 25 днів тому

      Agree

  • @RoyFoster-k3i
    @RoyFoster-k3i Рік тому +4

    Enjoyed the exchange between you both. I have been diagnosed with prostate cancer GS 7(3+4) and was recommended radiation. Still prayerfully considering my options. You provided amazing insight & information that was never shared by my Urologist. Thanks!

    • @DrGeoProstatePodcast
      @DrGeoProstatePodcast  Рік тому +1

      so glad you found it useful. All the best.

    • @ericmeshenberg3332
      @ericmeshenberg3332 10 місяців тому +3

      Insist on Genetic Testing ! Only then you will really understand your risks and benefits of treatment.

  • @josephngalamulume1635
    @josephngalamulume1635 11 місяців тому +3

    Very informative conversation! Thank you!

  • @glenquick414
    @glenquick414 Рік тому +3

    I found your channel today. Good stuff! I was recently diagnosed with gleason 3+4. 4 of the 12 cones came back positive. 3 were 3+3 and one was 3+4 with only 10% at 4. My PSA was a 4.3. I Just ordered your Regimen 1. Very expensive but im gonna try it!

    • @pinotwinelover
      @pinotwinelover 11 місяців тому +2

      What is regimen 1 do you have a link

  • @waynefoote3781
    @waynefoote3781 7 місяців тому +2

    Thank you very very much for your informational video.

  • @roger1uk676
    @roger1uk676 Рік тому +4

    Another great podcast/interview!

  • @richardreed6216
    @richardreed6216 11 місяців тому +3

    Dr. Geo
    Really liked interview with Dr. Siddiqui. One question I have is that in my second MRI guided biopsy it was a 7(4+3) with three cores being grade group 2, and two cores grade group 3, from my local urology group in Dallas, Texas. Through the PCRI UA-cam I learned that it might not be a bad idea to have a second opinion so I had my urology group send my slides to John Hopkins Pathology. To my surprise, it can back with much lower ratings which I have read is rare on a second opinion. The John Hopkins opinion was 7(3+4) with one core of 50% being 10% Gleason pattern 4, Grade group 2. The four other cores found were all (3+3) grade group 1 involving (20%), (10%), (90%) and (70%) respectively. Could you please comment.
    Last question, how much does 3 years of Finesteride affect PSA numbers. My latest PSA was 9.8 before my latest biopsy referred to here.
    Kind regards,
    Richard

    • @ericmeshenberg3332
      @ericmeshenberg3332 10 місяців тому

      Get on a testosterone suppressant as soon as possible !

    • @richardreed6216
      @richardreed6216 10 місяців тому

      Due to getting off anastrozole, which I had taken for years, my PSA has dropped to 5.93, since then, will get off Finesteride to check my actual PSA levels without it, (50% reduction with Finesteride). Is your opinion still the same?

  • @jeffschillermd364
    @jeffschillermd364 9 місяців тому +2

    quick question I have never heard spoken to. quick history active physician and active sexually, 74 yo
    new Dx 5x6 mm MRI lesion in a 110 gm prostate, PSA 9, PSA density .075,
    ONE positive core targeted plus systematic (12 cores) 5% Gleason 4. Sounds good right?
    BUT GPS score 61.
    I guess not a candidate for AS, but focal RX? Maybe TULSA? or whole gland? (I don't want it, as you already know. )
    Do you do consults Dr. Espinosa? I am in Manhattan.

    • @TERRY-cb2ku
      @TERRY-cb2ku 9 місяців тому +3

      @ jeffschillermd364 I understand quality of life is very important to all of us. I'm almost 73 and can still function sexually. I'm divorced but want to find a good mate eventually that I can spend the rest of my life with, and having sex is still important to me. I'm not going to be pressured or rushed into anything radical. Having said all of that, I also have to look at the odds of long term survival for my own sake, the sake of my children and grandchildren. PSA was never higher than 5.56 and last test was 4.3. I have an 8 mm lesion on the left anterior portion of my prostate. Pirads 4 shown on MRI scan. Getting biopsy done in the next month or two. If it's a 3+3 or favorable 3+4, I will opt for AS. If it's not favorable, I will consider external beam radiation. But again, I will not be rushed.

  • @ericmeshenberg3332
    @ericmeshenberg3332 Рік тому +4

    I did poorly on Orgovyx having severe side effects so had to stop. My prostate is way too big to be amenable to irradiation, so now shrinkage is not likely. I am 3+4=7. Waiting on my Genetic testing result. Active surveillance for me !

    • @ericmeshenberg3332
      @ericmeshenberg3332 10 місяців тому +2

      Follow up to my post. My Radiation Oncologist convinced me to go back on Orgovyx and try it every other day. Also my Urologist prescribed Estrogen for my hot flashes . Three months ago my Prostate was 146 gms. Now it has shrunk to 91.7, a manageable size for radiation. BTW, you don't want surgery ! Ive had the markers and the barrier placed and will soon have a CAT scan and consult to begin five sessions of radiation. Situation, hopeful.

  • @unapologetic7900
    @unapologetic7900 4 місяці тому +3

    Active surveillance for G7, yet most urologists go straight to RP for G8. Someone needs to finally get this figured out.

  • @gaudimaharaj709
    @gaudimaharaj709 Рік тому +1

    Dear Good Doctor, Totally confused . Hope you will simplify todays chat on your next broadcast. Specially regarding protocols , should we stop Keto now?

    • @pinotwinelover
      @pinotwinelover 11 місяців тому +1

      Yes he needs to answer since the guest specializes in metabolism is more toward fats feed prostate cells not glucose!!!

  • @alanrobinson2229
    @alanrobinson2229 7 місяців тому +2

    I went keto,my MRI scan suggested my cancer was " less prominent". So it reduced.
    But Dr Minaj just said prostate cancer feeds on fat more than suger,this is news to me and makes it very confusing.

  • @COLETHORN10
    @COLETHORN10 6 місяців тому

    I fought prostate cancer for pretty much all of 2017. What I learned was Gleason 7 (4+3) was much worse than Gleason 7 (3+4). I had the former but endured 45 straight days of radiation that has been successful to date of keeping the cancer at bay.

  • @anthonynwanokwale6324
    @anthonynwanokwale6324 Рік тому

    Hi Dr Geo, Thanks for what you do. I was diagnosed with Prostrate cancer in 2020 and had my first biopsy in 2021 after MRI and had Gleason 6 (3+3). I have been on surveillance and another MRI was done 10/10/23 and the size of the tumor have reduced almost by half from 1.1x0.8x0.6. to 0.6x0.6x 0.4. My doctor wants to do another biopsy, my PSA is reducing, last PSA 7.9 max is 8.9. and tumor is still within the prostrate and no abnormal symptoms so far. I was questioning why another biopsy if everything is improving. what is your advice?

    • @MM-sf3rl
      @MM-sf3rl Рік тому

      Thanks for sharing. I had no idea a lesion/tumor could reduce size. I’m surprised you had a biopsy with 3+3. Are have you changed your diet?

    • @anthonynwanokwale6324
      @anthonynwanokwale6324 Рік тому

      I have been on Keto diet for about 3 years. Doing intermittent Fasting 20 hours everyday. using supplements like D3 high dose.@@MM-sf3rl

    • @nickstrapko7549
      @nickstrapko7549 Рік тому

      @@MM-sf3rl You wont know without out a biopsy

  • @meridklt
    @meridklt Рік тому +5

    I'm not in the medical profession and at 80 years of age just a Joe Average male member of the public. The title 'Active Surveilance' and 'Prostate Cancer' caught my attention and so sat through the whole discussion. I found the continuous laughing really annoying and was most dissapointed that not once did age get mentioned relating to AS. Surely AS in 50 year olds and 80 year olds must be treated differently?

    • @MM-sf3rl
      @MM-sf3rl Рік тому

      Active Surveillance with a 50 year old or 80 years old is the same. But since the 50 year old has a longer expected live, is the cancer progresses, 3+3 then 3+4, then 4+3, etc., the under man would treat while the older may would probably not treat. As always, it depends of life expectancy, risk tolerance, and quality of life considerations.

  • @canyl
    @canyl 11 місяців тому +1

    Sorry i could not realize that, is it 4+3=7 gleasonscore grade 3

  • @F8Tributo
    @F8Tributo 11 місяців тому +1

    19:30- "Completely mundane to this topic?"
    Or maybe completely "germane"?

  • @pinotwinelover
    @pinotwinelover 7 місяців тому

    As or focal therapy is the only way to go with 3+4 if eligible

  • @ricknowak4582
    @ricknowak4582 5 місяців тому

    I recently had a third opinion for my prostate biopsy cancer. I'm trying to figure out the... "volume" of my "4" in my "3+4=7 Gleason. Can ANYONE help me. Here it is: " It involves approximately 90% of the sample the grade 4 is 4 mm". Another core reads..... " It involves approximately 40% of the sample. The great four present is in aggregate 2 mm". And the third one reads... " It involves approximately 8% of the sample. The grade four is 5 mm". I don't know what that... "MM" MEANS. Could it be just another word for.. " percent"??? Please anyone help me. And what does the.. "percent of the sample" mean.

    • @ricknowak4582
      @ricknowak4582 5 місяців тому

      I'm sorry the one said... "It involves approximately 80% of the sample"! NOT 8 %!!!

  • @canyl
    @canyl Рік тому +1

    Gleason 4+3=7 intermediate or not..

    • @MrGalo2012
      @MrGalo2012 11 місяців тому +1

      Top of the intermediate range. 3 on the new scale (1-5).of measuring

    • @spyderhead7160
      @spyderhead7160 10 місяців тому +1

      Intermediate.

  • @harrymaier2292
    @harrymaier2292 Рік тому

    Case A)
    1 Biopsy-Core 20 mm
    Cancerous tissue 15 %
    Pattern 3 (80%)
    Pattern 4 (20%)
    Case B)
    1 Biopsy-Core 20 mm
    Cancerous tissue 40%
    Pattern 3 (90%)
    Pattern 4 (10%)
    Which case is more favorable for the patient ?

  • @MikeMcKenna-b1c
    @MikeMcKenna-b1c 5 місяців тому +3

    Stop interrupting your guests so much. Otherwise, an insightful session.

  • @geoffmccoll4640
    @geoffmccoll4640 22 дні тому

    Shit I had my male tubes tied in 1992, it is not a wonder that my kids do not show up for Christmas Day?

  • @geoffmccoll4640
    @geoffmccoll4640 22 дні тому

    Just because you have a 7 Gleeson score, what should you say to a female radiation oncologist?

  • @geoffmccoll4640
    @geoffmccoll4640 22 дні тому

    If you did not want to watch the next non-nuclear war in the Middle East, You could use the words Prostrate Anomaly

  • @deemika
    @deemika Рік тому +4

    These two have a hard time staying on-topic. They'll start a sentence, and then say, "oh, by the way.." or "I'm pulling my hair out... even through I don'y have any...".

  • @budoconnor6126
    @budoconnor6126 23 дні тому

    With all due respect, please let him finish his answer.

  • @ricknowak4582
    @ricknowak4582 9 місяців тому

    I like like Dr. G but I do not like him making those... Agreeing, Very.
    Distracting and annoying sounds. Like...."uh hu". "Ys" " okay"!! very ANNOYING. don't they TEACH you THAT in Journalism School?!?! After EVERY sentence you make those um... "SOUNDS" !!! WTF !