I have an exam about this today and I was always confused about certain parts in this pathway. This video clearly and succinctly explains the pathway, thank you so much!
I'm glad you saved the simple explanation for the end because it helped me digest such a detailed explanation of all of the macronutrients it regulates by blocking them... I think 😅 Black seed oil 👍
1. AKT is an inhibitor of TSC1/2 2. TSC1/2 is an inhibitor if Rheb. 3. Rheb is an activator of mTORC1 AKT inhibits the inhibitor of Rheb (TSC1/2). Thereby allowing more Rheb to activate mTORC1 allowing for more activation of TSC1/2 as compared to if AKT was NOT present
Is GSK3 the same as GSK3-ß from Wnt-signaling (Activation of Akt leads to inactivation of beta-Catenin Destruction Complex, leading to a proliferative signal through a accumulation of beta-Catenin in the nucleus)? This would be an additional way how Akt stimulates cell proliferation?
Great Job! Really helpful! But in the part relation to Glycogen synthesis is little bit confusing to me. If possible please clear me! Does by GSK3 phosphorylation, GSK3 become inactive? and GS become phosphorylated or dephosphorylated?
Dear JJ Medicine, I wonder whether there is an email address I am able to contact you regarding your authorisation to use illustration elements of this material for scientific publication please? Any help is greatly appreciated. Kind regards, Olivia
Just started my research masters, this video is sweeter to my eyes and ears than any of my greatest youthful crushes.
I have an exam about this today and I was always confused about certain parts in this pathway. This video clearly and succinctly explains the pathway, thank you so much!
fantastic video on how AKT Kinase works. I learnt a lot. The author has a very lucid style of explanation. Thank you for posting.
I'm glad you saved the simple explanation for the end because it helped me digest such a detailed explanation of all of the macronutrients it regulates by blocking them... I think 😅
Black seed oil 👍
A very clearly and useful lesson, greetings from PERU
Very didactic and summarized explanation. Thank you¹
thank you for spending time and sharing your knowledge with us.
You are amazing! I wish I can be able to explain this clearly to my students just like you did. Thank you!
Super clear! Bravo!
thank you sossss much it was really useful
Thank you sooooo much!!
Thank you so much for this lecture. It was really really helpful ☺️☺️
Great. Thank you so much
Great video!
Thank you, it's pretty clear
Thanks mate, great videos
1. AKT is an inhibitor of TSC1/2
2. TSC1/2 is an inhibitor if Rheb.
3. Rheb is an activator of mTORC1
AKT inhibits the inhibitor of Rheb (TSC1/2). Thereby allowing more Rheb to activate mTORC1 allowing for more activation of TSC1/2 as compared to if AKT was NOT present
Very helpfull!! thank you so much
Very good explanation.
simply perfect. i wish you could do a similar video to the pathways involved in HSP90 alpha.
Amazign work!!!
شكراً جززززيلااااااا
Your videos are awesome
Keep up the good work!
Thank you
thx sir today my biochem exam has actually have akt pathway
Love u so much ...Thank you
Cool 😎 best ever video
Thanks
Very helpful. Thank you
Is GSK3 the same as GSK3-ß from Wnt-signaling (Activation of Akt leads to inactivation of beta-Catenin Destruction Complex, leading to a proliferative signal through a accumulation of beta-Catenin in the nucleus)? This would be an additional way how Akt stimulates cell proliferation?
nice video! What's the source of the image i can refer to?
Great Job! Really helpful! But in the part relation to Glycogen synthesis is little bit confusing to me. If possible please clear me! Does by GSK3 phosphorylation, GSK3 become inactive? and GS become phosphorylated or dephosphorylated?
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Why both Glycogen synthesis and Glycolysis are activated?
thanku
10/10
i’m 16. why am i here lol
Sncak vidio aktifkan dong?
Enjoy the content bruh
Dear JJ Medicine, I wonder whether there is an email address I am able to contact you regarding your authorisation to use illustration elements of this material for scientific publication please? Any help is greatly appreciated. Kind regards, Olivia
In writing