Ras Raf MAPK Pathway and Cancer | Mutations, Cancer Pathogenesis, and Chemotherapy

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  • Опубліковано 11 лис 2024

КОМЕНТАРІ • 36

  • @nicktokar2459
    @nicktokar2459 4 роки тому +19

    14-91% that range is absolutely massive

  • @tasbirmiah5247
    @tasbirmiah5247 6 місяців тому +1

    YOU'RE A LEGEND I FINALLY FOUND WHAT I NEEDED. THANK YOU. I WAS TRYING TO FIND A MECHANISM OF ACTION AS TO HOW BRAF GENE MUTATION CAN AFFECT MELANIN PRODUCTION AND I FINALLY FIGURED IT OUT.

  • @caramelizedonion6199
    @caramelizedonion6199 2 роки тому +5

    very informative and well made video. Thank you!
    Just one thing that might not be completely right: -mab is the suffix/ending for any kind of therapeutic antibody (Monoclonal Anti-Body) and not exclusively for those that target the EGFR.

  • @AymaraAnahi
    @AymaraAnahi 3 роки тому +9

    very clear and concise! made understanding a difficult topic much more achievable!

  • @suyasimatele
    @suyasimatele 6 місяців тому

    Great video. Very simplified, easy to understand

  • @divyanshikarmani
    @divyanshikarmani 5 років тому +5

    Thank you for the helpful prep for my finals! :)

  • @vicktorshushackov3074
    @vicktorshushackov3074 2 роки тому

    Guy you're cool. Thank you so mutch, it's very needful job that you do

  • @vinceblob4978
    @vinceblob4978 Рік тому

    Thanks it is very clear ! What are your sources to give these percentage of cancers ?

  • @TheBluebloop
    @TheBluebloop 2 роки тому

    this and the video before helped so much. thank you!! great work!

  • @abdullahnafea4736
    @abdullahnafea4736 2 роки тому

    Very clear and informative. Thanx

  • @internalmedicine9982
    @internalmedicine9982 3 роки тому

    This is a fantastic video

  • @poecilia1329
    @poecilia1329 2 роки тому

    Thank you so much for uploading this video!

  • @cristinepontes9348
    @cristinepontes9348 3 роки тому

    thanks for the great class

  • @olalalin5566
    @olalalin5566 3 роки тому +1

    Could you share the literature of H-Ras mutated in bladder cancer. Thank you.

  • @shbangash437
    @shbangash437 3 роки тому +1

    Hello sir . Can you please recommend a book from which you prepare all the pathways .

  • @Flaschenente
    @Flaschenente 3 роки тому +1

    Thank you for sharing this excellent lecture

  • @je6874
    @je6874 6 років тому +4

    What about the other EGFR-related proteins like HER2? Great video regardless!

  • @maydupnem9994
    @maydupnem9994 3 роки тому

    interesting, but which source did you use?

  • @mishalchaudary004
    @mishalchaudary004 3 роки тому

    Excellent explanation💞💯

  • @tahaagajani1755
    @tahaagajani1755 3 роки тому

    That was such a incredeble video thakns!❤

  • @helendodwell800
    @helendodwell800 3 роки тому

    could there also be mutations in RAS proteins to stop the activation?

  • @ikbaliremalkan4315
    @ikbaliremalkan4315 4 роки тому

    very well explanation ! thanks

  • @MuhammadJunaidAshraf
    @MuhammadJunaidAshraf 4 роки тому +2

    what about breast cancer from EGFR over expression? am I missing something or you didn't mention it?

  • @erdelyiinnovaciosmuhely2008
    @erdelyiinnovaciosmuhely2008 3 роки тому

    Great!
    May I underline a small mistake?
    Hematopoietic, not Hematopoetic.

  • @silviamoraleslopez9617
    @silviamoraleslopez9617 2 роки тому

    could you tell me the bibliography?

  • @felixromer4335
    @felixromer4335 2 роки тому

    there are 4 not 3 ras proteins. KRAS is devided into KRAS4A and KRAS4B because of different spleißing

  • @sylvesterhomsy1127
    @sylvesterhomsy1127 5 років тому

    Hairy Cell Leukemia has the most BRAF mutation

  • @evamathebula4448
    @evamathebula4448 6 років тому +1

    how can RAS be used to treat cancer cells

    • @mariahfoley2499
      @mariahfoley2499 4 роки тому +1

      If you block or inhibit RAS then it will stop the pathway and the transduction signal in nucleus will not be made. Thus decreasing cell proliferation and metastasis aka DEAD CANCER CELL

    • @medicojingle8416
      @medicojingle8416 4 роки тому

      ua-cam.com/video/kWHgDLYaj_4/v-deo.html

  • @fernsader9261
    @fernsader9261 4 роки тому

    Where are you pulling all this info from? What studies lol

  • @paulawad9585
    @paulawad9585 7 років тому

    are u canadian?? ur accent sounds super canadian lol