Aldehydes and ketones undergo a variety of reactions that lead to many different products. The most common reactions are nucleophilic addition reactions, which lead to the formation of alcohols, alkenes, diols, cyanohydrins (RCH(OH)C&tbond;N), and imines R 2C&dbond;NR), to mention a few representative examples.
thank you ... sorry but i have a quick question : in the last example you reacted ketone with ( CH3Li ) not with (CH3MgLi ) my question is does it the same i mean it doesn't matter if i react ketone with grignard or with alkyl-Li ? :)
There is no carbocation formation thus there won't be rearrangement. -in any case it would remove the aromaticity of the benzene making it less stable -hypothetically speaking
Karri Nagesu the only grignard to get a primary alkohol is with formaldehyd, if you use another aldehyd youll get a secondary alk. and if you use a keton youll get a tertriary alk.
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Aldehydes and ketones undergo a variety of reactions that lead to many different products. The most common reactions are nucleophilic addition reactions, which lead to the formation of alcohols, alkenes, diols, cyanohydrins (RCH(OH)C&tbond;N), and imines R 2C&dbond;NR), to mention a few representative examples.
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what happened to the hydrogen in example 3 ?
at 5:52
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In the minute 9:56 you obtain OH? Or is H2O
Thank you for explain
Good
thank you ... sorry but i have a quick question :
in the last example you reacted ketone with ( CH3Li ) not with (CH3MgLi ) my question is does it the same i mean it doesn't matter if i react ketone with grignard or with alkyl-Li ?
:)
Acyl chlorides do react with NaBH4! They undergo 2 succesive reactions with NaBH4.
(Source: Organic Chemistry P.Y Bruice 7th edition)
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Is CH3Li (last example) considered as a hydride reagent. Does it work like LiAlH4? Thank you by the way! Very clear
Samuel Swanzy no. it works just like grignard's reagent. the oh- obtained from hydroysis will combine with lithium.
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Will not there be rearrangement in the second example and the hydroxide will attach to the benzene ring?
There is no carbocation formation thus there won't be rearrangement.
-in any case it would remove the aromaticity of the benzene making it less stable -hypothetically speaking
Thank you but aldehydes react with griganard to get primary alcohols .ketones react with griganard to get
Karri Nagesu the only grignard to get a primary alkohol is with formaldehyd, if you use another aldehyd youll get a secondary alk. and if you use a keton youll get a tertriary alk.
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What will happen if I react 1 degree alkyl halide with LiAlH4 and NaBH4 separately?
Apoorv Tyagi if u treat that then reaction padkinxa
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