What Are: Knockout Mice?

[@Cyagen]

More information about our knockout mice could be found at:
www.cyagen.com/us/en/service/crispr-based-genome-editing-knockout-mice.html

[@rhyslormand703]

Explained 100x better than my professor! Awesome video.

[@Cyagen]

Thanks, we are happy it helped better explain knockout mice for you!☺

[@zhansayabauyrzhanova2492]

Perfect explanation

[@mjh5437]

I saw something earlier about fat-prone mice and thin-prone mice and hairy-prone mice and bald-prone mice being created.

[@izzyp1162]

quick and easy explanation, thanks.

[@jagannath6280]

you are so good brother. thank you

[@timeaboroczky3364]

Thank you ! very helpful and informative

[@Senara_99]

Thank you very much! ❤️

[@KevinT]

Hi Cyagen I have a quick question: how are we putting an antibiotic resistance gene into a eukaryotic cell? The stem cells from the blastocyst are from a eukaryotic organism.. so I'd assume that antibiotics wouldn't be able to kill these cells anyways? Please let me know if I'm misunderstanding something. Thanks!!

[@jumanajamal8945]

I was actually wondering the same thing, why do we add neomycin, if eukaryotic cells don’t get affected by antibiotics.

[@yonetmen]

Is there anyone here who can explain to me why do we always obtain heterozygous cells after homologous recombination?

[@ashwinimurthy8733]

Bcos AA *aa =Aa crossing over

[@richashrivastava3981]

If we do PCR of all ESC, how are we left with cells to be implanted in the new mice blastocyst?

[@Cyagen]

Typically, one or more subcultures of cells can be made for analysis and selection of the correctly modified cells.

[@richashrivastava3981]

Thanks@@Cyagen

[@michael2539]

Very helpful. Thanks

[@shri_harshabhat4069]

Pls send notes of this

[@Cyagen]

Thanks for your interest in our knockout mice. More information could be found at: www.cyagen.com/us/en/service/crispr-based-genome-editing-knockout-mice.html

[@zhansayabauyrzhanova2492]

Thank you!

[@divinaryf3703]

thank you!

[@sanchitapaul1223]

Thats helpful.

[@ive1111]

Just wondering, are there technologies or drugs that can knock out Genes by simply giving oral drugs while being pregnant?

[@Name-zd5fq]

Nobody:
Pfizer: "Let's knock out humanity!" :D

[@lucasjones3338]

Yeah, after I got the vaccine I stopped existing.

[@Name-zd5fq]

@@lucasjones3338 You will never have children.

[@KlearChristal]

@@Name-zd5fq pretty sure thousands of vaccinated people have already had children lol

[@Name-zd5fq]

@@KlearChristal LOL...let's see how long you'll laugh. :D