Drugs that slow ageing in mice | Prof Richard A. Miller
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- Опубліковано 7 лип 2024
- In this #webinar, Professor Richard A. Miller, a Professor of Pathology in University of Michigan, shared a summary of the progress made by Interventions Testing Programme and some new data and ideas on Ageing Rate Indicators.
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References:
Closing video source: • UK's oldest person Gra...
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Thank you NUS, please have this researcher back soon - he has much more to share with us!
This is an A1. Must watch again video. Thanks to all. Happy New Year too.
Great to see the discussion on rapamycin and the other longevity drugs. Many people are using and seeing success with these drugs (by their measures).
Really interesting presentation, definitely worth viewing and would like to have him back!
Awesome “ do a lot of push ups and eat broccoli etc “ Appreciate his honesty 👌 thanks again for posting this video.
Brilliant to hear the results. See you in Dublin Brian
At the end a reason to disagree. With the discovery of Bio-electricity and "Morphogenetics" a different approach to controlling DNA/RNA codes. Well worth looking up and revolutionary. Yes we can, for real. Reverse and control the ageing process and with that address the root causes of most if not all disease. Intended to be helpful not argumentative in the non scientific sense. Happy New Year again.
Nice talk Rich. Water contaminants : you should do RO filtering and add back defined electrolytes
So, regarding the differences in male and female mice responses, if the activation of retrotransposon and concomitant loss of epigenetic programming is true, could the female chromosomes be more protected because of Xist silencing? Maybe protecting both the silent and nonsilent? By comparison, males would have more loss of silencing of their 1 X and on top of it the Y? Drugs that target pathways more disrupted in males because important genes residing on the X in those pathways would have more effect. Anyone tested that? Or even, tested XYYY males. Or XO females?
Great and informative content. On somewhat unrelated note, I find an introductory jingle and the footage showing damaged, wrinkled, aged barely moving people confusing. Aren't this what we are supposed to fight? Isn't the idea to make them biologically young again so that they can contribute to society with the wisdom and knowledge they acquired?
It seems nothing can truly measure the inescapable nature of chaos
As for "Amazing Grace" I hope she lives for at least 10 thousand years.🙂
Looking forward to further research in this field. What about drugs that slow aging in rats ?
Enjoyed this researcher's input. I would also like to see use of AI in research as well. Is there current pairing of AI in the area of longevity research?
Rapamycin plus acarbose is not the first intervention that produced a better effect than either drug alone. Rapamycin plus Metformin is the first. It seems odd not to mention that.
curious if gene editing can be use on mice some time in the future?
Glycine + NAC
Glycine + NAC + selenium + glutamine
OK, I'll head onto the website to propose a drug named Oridonin.
We probably can get some 5 or ten years more of life. Though with an special diet also get near the same
Researchers should employ AI artificial intelligence in scanning possible chemicals to be tested using all past chemicals as reference, I believe AI would not only help to find promising hits, but also should be used to screen future recommendations, to help prioritize most promising tests to target as priority. Of course continuous results fed back into the AI programs, will help fine tune, improve selection process hopefully.
They do this already.
@@juliahello6673 Ok so is the Biblical tree of life a literal possibility, as in if they do this already, what chances are there of combining Organic and chemistry so that it grows on fruiting trees, so humans can eat in nature ? Then their life will be extended. Example, if Taurine, Glycine and NAC extend lifespans, what else and combine it all into a fruit tree. Are they working on that ?
Mouse in trap with crash helmet. lol. Now that's stretching adaptation and evolution a bit far.
11:40 He says quercetin but Its fitesin I guess.
I think this professor is too skeptical about certain possibility , conceptually excluding them as he does, certainly dosen't give you the way to activate them and limits you to new frontiers yet to be discovered and conquered . This professor maybe he's good in his field , but maybe he's also a bit too limited . If Einstein was skeptcal in finding new solutions to the problems of gravity and beyond he would never have discovered the theory of relativity and we would still have Newton's laws valid up to a certain point but not complete.
lol "dinitrophenol"? are you serious lol
The intro is annoying...... I am not here for pop music.... Or put a time stamp...