Pharmacology of ADHD Medications: Amphetamine & Methylphenidate
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- Опубліковано 10 гру 2021
- Attention deficit hyperactivity disorder (ADHD) is commonly treated with psychostimulant drugs like amphetamine and methylphenidate. In this video, I will take a brief look at the basic pharmacology behind these stimulants.
I'd be happy to hear your thoughts and continue the discussion down below in the comments section.
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References:
Amphetamines, new psychoactive drugs and the monoamine transporter cycle
Harald H Sitte, Michael Freissmuth
PMID: 25542076 DOI: 10.1016/j.tips.2014.11.006
Attention deficit hyperactivity disorder
Anita Thapar, Miriam Cooper
DOI:doi.org/10.1016/S0140-6736(15...
The pharmacology of amphetamine and methylphenidate: Relevance to the neurobiology of attention-deficit/hyperactivity disorder and other psychiatric comorbidities
Stephen V Faraone
PMID: 29428394 DOI: 10.1016/j.neubiorev.2018.02.001
Cardiovascular effects of medications for the treatment of attention-deficit hyperactivity disorder: what is known and how should it influence prescribing in children?
Josephine Elia, Victoria L Vetter
PMID: 20481646 DOI: 10.2165/11532570-000000000-00000
Time-release mechanism original video, courtesy of Sebastian Vergara:
• Concerta time-release ...
#ADHD #pharmacology
As someone who is both in neuropharm and has ADHD (for which I take dexamphetamine), I was very impressed by this overview! It was unbiased and you didn't skip over anything crucial.
I’ve tried both methylphenidate (concerta) and amphetamine (lisdexamphetamine). I found amphetamine definitely gave me more focus and made me feel like I had to be doing something. I also got very anxious, dry mouth, sweaty, all the things mentioned in the video. However, I found methylphenidate is amazing for me. I would say definitely a slight euphoric sense but no anxiety or crazy crazy amount of focus. For me it more so helps with motivation. I can task switch in work without forgetting what I was working on initially. Even when it comes to criticism or arguments I am a lot better at staying calm and dealing with them logically or taking advice on board.
It took me two separate prison sentences to get help, I just couldn't get the help I needed and I ended up in a ward were I was diagnosed if you think you have adhd save your self the heart Ache and get it sorted asap before you burn your bridges
Alternative medication can be voxra( wellbutrin) Strattera, and also buspiron actavis which can be either added or as a sole therapy.
I've developed ADHD as an adult. I believe a lot of the reason is because of chronic pain from two cervical fusions and taking different prescriptions of several opiates over the last 11 years. Just wondering if you can explore this. Because I still take tramadol daily and hydromorphone rarely when the pain is extreme, my doctor will not prescribe amphetamines. I've always been confused by my opiate use because I've never felt a high of any kind. They've also never given me a sedating effect. Alcohol had always been best at pain relief, but I can't function, so I've been nursing the same bottle of Jim Beam for the last year. Tramadol really just makes me care less about the pain, but never actually gets rid of it. Any thoughts you have about this would be insightful.
Could you talk about other study drugs such as the racetams? I've seen that drugs like pramiracetam, etc. are particularly popular for cognitive boosting in the nootropic community, but don't really understand the mechanisms why.
What is the generic of concerta
why would you give kids speed
anyone that is smarter, can see, a system others are trying to limit them into criminal?
phendimetrazine god tier lol
Love the video!
Thank you so much for your amazing content!
I liked a lot your videos! I just discover your channel and I'm happy to see this content about ADHD medication. I was recently diagnosed with this disorder (at 44 and one month taking medication). I'm taking lisdexamfetamine, kinda regulating dosage, and trying methylphenidate for specific days when I need to regulate my rhythm, all under medical supervision.
Great content, I'll be watching all your videos asap!
You nailed the exact effects and history of my ADHD meds. The psychosis after I kept upping my dose, the anhedonia, hyper tension etc. I wish there were other options because I function so well on them but can't take the side effects. I do not take them anymore unless I really, really need them (couple times a year). I hate this condition. You're probably going to think it's a bad idea, but I have been using redbull (zero no sugar version) and Kratom. It's not as good as my meds but is a hell of a lot better than nothing. And I don't get the horrible hangover and anhedonia.
As always great content - 👁️
you need to make a part 2!
Great video. Very informative.
Good stuff
I use kratom and lisdexamphetamine. Kratom reduces the stress I can get from the amphetamine. It works ok. Don't know if it's safe long term though. Sometimes I get aggressive migraine and puke my guts out for 12-24 hours.