ACE inhibitors SAR, SAR of antihypertensive drugs, Medicinal chemistry made easy

sar of ace inhibitors, structure activity relationship of ace inhibitors, sar of ace inhibitors medicinal chemistry, sar of antihypertensive drugs
📍 Angiotensin-converting enzyme inhibitors (ACEIs) are the most commonly indicated medications in the treatment of cardiovascular and renal diseases, including heart failure, acute coronary syndrome, nephrotic syndrome, diabetes, and hypertension.
📍 The structure-activity relationship (SAR) of angiotensin-converting enzyme (ACE) inhibitors refers to the relationship between the chemical structure of these drugs and their pharmacological activity, particularly their ability to inhibit ACE and lower blood pressure.
📍 Overall, understanding the SAR of ACE inhibitors is crucial for rational drug design and optimization of pharmacological properties, such as potency, selectivity, and bioavailability. By exploring structural modifications and elucidating their effects on ACE inhibition, researchers can develop more potent and efficacious ACE inhibitors for the treatment of hypertension and other cardiovascular conditions.
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Chapters:
0:00 - ACE inhibitors pharmacology
0:22 - ACE inhibitors mechanism of action
0:47 - Examples of ACE inhibitors
1:00 - Side effects of ACE inhibitors
1:09 - SAR (structure activity relationship) of ACE inhibitors
1:46 - SAR (structure activity relationship) of Captopril
2:05 - SAR (structure activity relationship) of Enalapril
2:26 - SAR (structure activity relationship) of Fisinopril
2:50 - ACE inhibitors patient counselling
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Disclaimer:
"Content is For Informational & Education Purpose Only, Creamed From Various Authentic Books of Pharmacy & Medicine. The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition."

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