Molecular Dynamics of the respiratory supercomplex III/IV

🌀 In mitochondria and many bacteria, reduction of the dioxygen electron acceptor is catalyzed by cytochrome c oxidase (complex IV), which receives electrons from cytochrome bc1 (complex III). These enzymes are collectively referred to as the respiratory chain because they are wired to transfer electrons consecutively, driving cellular respiration and energy production.
🔮 This animation illustrates the all-atom molecular dynamics of the bacterial supercomplex III/IV in an explicit membrane environment with a focus on its structural flexibility. Let's explore the structural insights that can facilitate the development of new antibacterial therapies!
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