Get Surfshark VPN at surfshark.deals/drhope Enter promo code DRHOPE for 83% off and 3 extra months for FREE! Best episode of the season yet; the ending was a rollercoaster of emotions! Let me know your favourite part of the first season...
Great reaction, however I was quite surprised you didn't comment from a medical POV on the whole cannibalism thing which was one of the major events in this episode.
It's kinda twice funny if you think about how the whole episode built up to Joel coming to save Ellie. (like a fever dream) But in reality she did it herself. Which I mean is the absolute emotional gut punch, but yeah!
Most of the violence up until this point has been people trying to survive, but David is the first truly malicious person that Ellie encounters, and encountering someone who is ACTUALLY enjoying hurting you is one of the express lanes to trauma. And I second the bravo for the acting at the end, you can practically watch the PTSD build up on her face in real time, what a performance. Cheers
The acting was brilliant. Also the the dude who played David was SO good; especially considering he was only introduced in this episode, he felt like a fully fleshed out villain.
@@DrHopeSickNotes fun fact. The Acting is so impeccable that the scene where Pedro catch Bella after the assault scene was shot first BEFORE the assault scene.
Saying he voiced Joel feels like not cutting him enough slack. With all the motion & facial capture involved in the games, I think it's fair to say Troy fully acted the role of Joel
There is a theory that he uses the "ex-teacher" line as a way of making himself seem more upstanding, not just to Ellie but also to his 'flock'. He may well be a fantasist as well as a psychotic narcissist. Either way he's a monster.
Honestly I'd have been perfectly happy with Ellie knowing how to give penicillin from FEDRA school, or Joel being conscious enough to help her (he'd surely know how at this point in his life) and the suspense being whether he was ambulatory. He would be concerned about the people she got it from, which they could fight about, and be mentally trying to get himself functional.
@@DrHopeSickNotes would an adrenaline rush from fighting for your life be able to build enough blood pressure to power through septic shock, or is that just Holly Wood?
The local injection was something I really wanted to hear your response to, with limited knowledge it makes sense to me that Ellie did it, and it's probably what I would do in the same situation, but great to hear about the specifics.
Yeh I wish I knew more; I had a quick browse online after the show and appears we can give some antibiotics subcutaneously (when we can't get IV access) but this is very different to injecting a wound infection! And there was also an article that we can inject antibiotics into abscess when they are difficult to drain. So actually probably would have benefited Joel. The main issue that.I didn't hammer home enough was that two doses isn't a lot. You'd expect him to need at least 3 - 4 doses a day for 3-5 days IV and then step down oral antibiotics for 2 weeks.
@@DrHopeSickNotes Is 1 bottle really just 1 shot? I figured you would use one bottle for like a week's worth of doses. Are there larger bottles like this, or do you usually use up an entire bottle for one injection?
@@holysecret2 I imagine it has to be 1 bottle = 1 shot, because once you break open a large bottle, it's not sterile. But that's just how I imagine things work, I'm not a doctor and don't claim to know for sure.
@@holysecret2 Perhaps, but also remember Ellie is no expert. She doesn't know how much to give or where to inject it. So she just puts as much into the syringe that "looks about right" for a 14 year old girl who has no experience. She has no idea that the bottle is no longer sterile. If it even occurred to her, she would probably think hey this stuff kills germs, right?
@@VadBlackwood not a doctor but I do weekly subcutaneous injections and can safely reuse a vial so long as I rub an alcohol wipe over the rubber stopper every single time - the rubber sorta closes back up around where the needle went in, my needles are all new, and I'm only using it for myself so it's not a big deal.
Bella Ramsey managed to upstage Pedro Pascal in the acting stakes in a lot of episodes in this series, we know Pedro is a great actor but damn does Bella deserve an award for her acting in this
Ed man.... you paused it at the wrong time! When she stops and he says "It's me babygirl, you're safe". That is one of the deepest and most moving of the whole season.
As someone who reads a lot of Medal of Honor or Victoria Cross citations, “went into beast mode” definitely has to be the medical term for that blend of adrenaline & will power to accomplish seemingly impossible feats.
I've never gone into septic shock, but I've had a few surgeries that required I be under a general anaesthetic. I warn the medical staff because when I wake up, my brain only knows that I've been hurt and I don't know where I am. I *will* try to get up and leave, and I am willing to fight anyone who tries to stop me. (This is apparently common enough that when I tell them I'm prone to do this, they just say, it's okay we can handle that.)
Not only am I looking forward to you covering the medical stuff in episode 9, I’m also interested in your evaluation of the ethics of both the fireflies and Joel regarding what happens in that episode
Me, watching this intro again: Oh, I just realized what venison, elk and rabbit is code for Doctor: *explains rabbit poisoning* So they need more than just really lean meat, they need something with fat as well Me: *looks at camera*
THANK YOU for not critisising Ellie when she injected the antibiotics straight into the wound. She's a 14 year old girls who's lived a very sheltered life in a post apocalyptic dystopian society. She would have absolutely no idea what to do and putting it into the wound was a totally understandable guess. I have seen other youtubers critisise her actions in this scene, without taking into account that shes LITERALLY 14 YEARS OLD WITH NO MEDICAL TRAINING. Most people I know wouldn't be able to inject a needle at all!
I don't know what I've enjoyed more The Last of Us or Dr. Hope's Sick Notes about it! The fact that you're clearly a fan of the show makes the medical critique a fun addition to the story, I'm really looking forward to your review of the finale.
Yeh I was going to put Cells at Work bacteria on screen when I mentioned them, but then it might have been a confusing reference for some people! I want to get back to that show again, loads more episodes to cover
I'm surprised the eating people thing didn't come up because I think that has some medical issues behind it although not sure as I have never done it myself
I once heard about a guy who ate a polar bear or Polar bear liver and died almost immediately because it was like 100% protein. Could've been an urban legend but your explanation of eating just rabbit made me think. This episode was brutal but Bella deserves every acting award imaginable. I love your reactions!
Thanks for the comment! Yeh I think polar bear livers have lots of vitamin A; which is fat soluble so difficult for your kidneys to get rid of toxic levels; so you effectively get an overdose. I learnt that from watching QI
nothing breaks me quite like the moment where ellie leaves the burning building and joel goes to comfort her and she just. struggles. the hurt, this inability to trust, the utter breaking down. it's definitely the most raw scene in the entire show. then she fully realizes that it's him and that she's safe and she just realizes that he's home and that it's all over and it's the most beautiful thing in all of television
I have thought of all the deficiencies in these peoples' diets too. Unless they were grinding up bones, they weren't getting any calcium either. No B vitamins, no carbs, no Vit A or C. If they don't have rabbit poisoning, they have scurvy or nutritional secondary hyperparathyroidism
Good episode. From how fast Joel recovered I wondered if that antibiotic had some adrenaline in it lol. I did find it odd you skipped the part where Joel stabbed the guy in the knee.
Yeh I actually talked about the knee injury, but cut it in the edit as the video was getting so long; likely ruptured the quadriceps tendon and left his patella all flappy.
The season finale’s major plot point is contingent upon a desire to embark on a medical venture that I regarded as highly dubious as a layperson. Since I don’t want to spoil, I won’t say more than is necessary to frame my question to Dr. Hope: what is the likely utility of this plan medically? I grant you that it’s dealing with a unique case in a worldwide pandemic of a fictional fantasy fungal disease. But given all of the context that is available, including what little medical materials and expertise would have survived into the post-apocalypse, what’s your best ballpark estimate that this experiment would have been worth what it cost?
Man I love you’re videos and your medical breakdowns (super interesting!), but honestly I’d also just love to see more of your general reactions to the rest of the episode! I’m sure I speak for other supporters of your channel, but we’re here for you yourself, as well as your medical knowledge! Keep up the good work!
Loved the reaction as always!! I laughed so hard at the delirium and beast-mode parts 🤣🤣🤣🤣 I thought you were going to comment on the cannibalism fact and Kuru disease, the reaction was amazing nevertheless!! 😃😃😃
I've been waiting for this video to get resolution on the injection question. I guess I could have looked it up, but that's what I have Dr. Hope for! Second question: would the instructions for the penicillin typically be printed on the label?
For next episode I expect a lot of psychology analysis on Joel's actions. If you have anyone experts on psychology around you, I would suggest you to watch last episode with her/him.
16:35 Imagine playing the game man bro u had to constantly sneak attack David and it was one of the creepiest parts of the game ..... And by the way Joel actually sneaks up and stops Ellie in the burning restaurant .......
In the videogame (from what i remember) she would actually feed him and make him drink lots of fluids. She traded 2 deer for a box of penicillin, and a surgical first aid kit. She actually was seen studying a medical book in the vido game.
My father is in his 70s. He started have little seizures from time to time. You can’t tell unless you really pay attention. The doctors say a head in jury from when he was younger could now be causing this so many years later. He was thrown from a horse on a gravel road as a child and had a head injury. He got knocked out playing high school football. He was also a passenger in a fatal car accident as a middle schooler and was knocked out. He came to before anyone else and flagged down help. He was more injured than anyone realized until after they got everyone else to the hospital. (His brother was driving and they were hit head on by a drunk driver. The drunk driver was the one that died, but several of my dad’s brothers were injured, though they all recovered.) would these incidents have waited over 50 years to start causing seizures?
@@RogueDemagogue The problem with eating brains is that’s how you get all kinds of fun prion diseases and then we’ve got a WHOLE DIFFERENT kind of zombie problem
People who have been in situations where they've had to eat other people have had the trouble where the people they eat have so little fat by that point the person eating them has got rabbit poisoning.
i dig this, ive seem other medical channels, but your actually watching the show with some investment in the characters and that mate, thats how u get a new subscriber
I am a horse rider and have had a number of falls resulting in injuries - two broken wrists and potentally bruised and/or broken ribs (never saw the Dr. but probably should have considering the pain I was in for months afterwards) The 2nd time I broke my wrist, although not suffering a concussion (that I know of) I still experienced many of those same symptoms Ellie did - I started sweating profusely, ringing in my ears and everything else sounded like I was underwater. My vision went totally black and white and I couldn't see any colour. I was very dizzy nauseous. Still - I got back on the horse and kept riding for another 15 minutes until I dismounted and took my glove off, realising how swollen my wrist had become in that time! The feeling of absolute confusion and dread that comes after being thrown off a horse is one in a million. Nothing else like it.
How much adrenaline do you think his body would pump if he thought of her as his daughter and then felt she was in danger? would enough course to get him to his feet? I am also wondering once the adrenaline wears off if he would not just collapse unconscious
That was interesting information about re-opening the wound in cases of bad infection like that. It's not something that seems intuitive, so I will definitely have to file that away in case I ever have need of that type of treatment in an apocalyptic scenario.
this had to be the best review of this series yet, oof, you do know your stuff lol in an apocalypse a doctor could be your best hope or your worst enemy, with their knowledge of the human body! LOL one thing for sure if this does happen in real life, I'm head to the UK to meet up with him!
Is human IV penicillin cloudy? I was taught in vet tech/nurse school that the only non-clear solution that should go IV is propofol. And while not all clear things can go IV either, cloudy solutions should be IM.
I wondered what your opinion would be about their cannibalism. What type of diseases might be transmitted. Their leader was truly the real villain of the story so far, I'm happy he got his karma served. You are doing a fantastic job, I love the array of human emotions on your face as much as the medical info. It's a human bonding experience.
I’m a doctor as well. I don’t think cannibalism would be a problem health-wise, you would probably want to avoid eating the nervous system like the brain and spinal cord to minimize the risk of getting a prion disease (like kuru or other transmissible spongiform encephalopathies like (variant) Creutzfeld Jakob disease, Gerstmann Sträussler Scheinker syndrome and fatal insomnia, although all of these are extremely rare but you wouldn’t want to eat the body of somebody who has them, since they are transmitted through misfolded proteins (prions) which in turn cause other proteins to misfold and can’t be destroyed by cooking. Also, I know eating some organs like a polar bear’s liver causes deadly vitamin A poisoning, but I’m not sure if it would be safe to eat a human liver. Ritualistic cannibalism has been a part of various human cultures over the course of history, and has also been used as a last resort in periods of extreme famine (for an interesting, if not horrifying, event which features cannibalism, google Donner party)
I also was curious about cannibalism. My husband works at the medical book store at the campus and each year after the students had their first human dissection a lot of them talks about how creepy it was that they got super hungry during the dissection...
I've really enjoyed these reactions and reviews a lot. I hope you do season 2 when it comes out and maybe even check out Hannibal at some point to analyze.
As always Doc, a stellar review of the injuries to help educate the rest of us non-medical people :D The show by this point is having to skip over MASSIVE amounts of story contained in the game to shoehorn a TV show in. TLOU1 in the game while the show did it a credit in so many ways, the show also cut incredible amounts of story. The cannibalism aspect here you didnt even go in to as well. The game expands a lot on this section of the story. But the character that played David the preacher did a 15/10 job. He came off as perfect according to the game and the director stuck HARD in many places right to the game. The acting all around for what they did allow was BRILLIANT. I am freaking a bit about show 9. What else will the show change but also have to cut?
09:15 So regarding the whole "Stay awake, stay with me!" thing in movies (not losing consciousness when near death), is that actually a thing (medically) or not? I know for the PATIENT they may want to stay conscious as they may not know if they'll ever wake up again. But medically is this the best thing for them? Considering you're probably losing consciousness for a reason (to go into low power mode). Therefore, is there any medical benefit to forcing the patient to remain conscious when near death, or are you more focused on just keeping their vitals going? (Pulse etc)
I'm not a doctor so I dont' know about all situations in emergency medicine. I do know that there are some situations where telling the person to relax can be unhelpful, specifically rescuing people who are suffering from hypothermia. When emergency rescuers are airlifting people out of cold water (like if they have been floating in lifejackets after a ship sank), rescuers used to reassure the person when they got to the helicopter "it's okay, we've got you, you're safe now". The person would relax, their blood pressure would drop, and they would die. Now that is known, the best practice when rescuing people is to say "we're going to help you but we need you to keep fighting". Adrenaline raises blood pressure and makes you breathe more deeply. When you sleep, your blood pressure drops and your breathing is suppressed. In some cases being afraid and knowing that you could die if you relax can help keep you alive, but it depends on the type of emergency. For a lot of illnesses rest and sleep is what you need so you can heal, and stress is unhelpful. I'm not sure whether just "try to stay concious" is ever helpful, but it might be in some cases.
Yes, don’t fall asleep Joel. By all means, don’t fall asleep while lying down in a dimly lit quiet place.... Skipped right over the cannibalism eh... now I’m no doctor, but it seems to me, that cannibalism, if you set aside the prion related dangers and socially stigmatizing ethical issues, it seems to me, that cannibalism is a great way to avoid rabbit poisoning... 🐇
I’m allergic to amoxicillin and so my doctors don’t use penicillin for me. What should I try to look for if I’m in the apocalypse, besides giving penicillin the old college try?! 😂
Also wouldn't the antibiotic formulation in this case be most effectively administered via IM injection, especially considering the nature of Joel's condition? In cases such as these involving severe secondary infection and systemic symptoms, isn't it not uncommon to administer doses of certain antibiotics via IM injection before following up with a course of oral and/or IV antibiotics? Essentially this delivers a large dose that can be rapidly absorbed and metabolized to kickstart the fight before the following consistent treatment with more reasonable therapeutic doses. Sorry if my phrasing is a little screwy right now, I'm running on very little sleep with chronic insomnia so I'm a kinda "bleh" and perhaps a little slap-happy right now...
Hey Dr Hope! Could you make a video explaining Toxic Shock Syndrome? So many videos on Tiktok are demonising tampon use and claiming it’s a really common condition, and I am very confused.
Wonder if you can do Code Black next. It would be really interesting how it is handled in UK if it happens that you have more patients than doctors/nurses.
Get Surfshark VPN at surfshark.deals/drhope Enter promo code DRHOPE for 83% off and 3 extra months for FREE!
Best episode of the season yet; the ending was a rollercoaster of emotions! Let me know your favourite part of the first season...
Great reaction, however I was quite surprised you didn't comment from a medical POV on the whole cannibalism thing which was one of the major events in this episode.
"this guy might be in a bit of trouble, but TBH, I DONT GIVE A CRAP!"
I laughed so hard at the delirium bit about joel slowly dying while imagining himself torturing people in the livingroom haha
I'm absolutely dying right now because of that part.
😂 loved the edit, chef's kiss 😘 perfect
It's kinda twice funny if you think about how the whole episode built up to Joel coming to save Ellie. (like a fever dream) But in reality she did it herself. Which I mean is the absolute emotional gut punch, but yeah!
Joel’s fantasy lollll
Super great editing, loved it
"He's into beast mode!!!" is my favorite medical diagnosis in this episode. Thank you Daisy for the emotional support! 😻
Daddy bear is on a mission
Joel has a condition known as Chronic Beast Mode. You'll see it again in sufferers of this condition where they wreck fools who cause a ruckus.
Most of the violence up until this point has been people trying to survive, but David is the first truly malicious person that Ellie encounters, and encountering someone who is ACTUALLY enjoying hurting you is one of the express lanes to trauma. And I second the bravo for the acting at the end, you can practically watch the PTSD build up on her face in real time, what a performance. Cheers
The acting was brilliant. Also the the dude who played David was SO good; especially considering he was only introduced in this episode, he felt like a fully fleshed out villain.
Bella obviously. Also Pedro, the combination of relief, heartbreak at finding Ellie in that condition, and pushing it aside to be what she needs.
The fact he was a teacher before the Outbreak is extra vile.
@@DrHopeSickNotes fun fact. The Acting is so impeccable that the scene where Pedro catch Bella after the assault scene was shot first BEFORE the assault scene.
@@DrHopeSickNotes Not sure if anyone else has told you that the actor playing David is Troy Baker who plays Joel in the games :)
Fun Fact: Troy Baker - the actor who plays James in this episode - voiced Joel in the video game.
Aww cool!
@@DrHopeSickNotes a bit poetic that the Ellie in the show kills the person that plays Joel in the game
@@Chris_W. at least she didn't use a golf club
@@Ads_SnapsLOL
Saying he voiced Joel feels like not cutting him enough slack. With all the motion & facial capture involved in the games, I think it's fair to say Troy fully acted the role of Joel
When you talked about how they couldn't be healthy with just rabbit and venison meat, I just started laughing out loud for the irony
@@RogueDemagogue The irony being that they were mostly eating humans, and not rabbits.
@@RogueDemagogue 7 billion people are dead\infected at this point.
Dr Ed: "oh man these people really need another source of fats and carbohydrates."
Me: Oh man he's gonna learn they ain't too worried about that.
The fact that David was a schoolteacher too 🤮 god what a villain
There is a theory that he uses the "ex-teacher" line as a way of making himself seem more upstanding, not just to Ellie but also to his 'flock'. He may well be a fantasist as well as a psychotic narcissist. Either way he's a monster.
"He's entered beast mode." is probably the best explanation I've seen as to what Joel is going through this episode.
Those are the hot medical takes you come to this channel for!
Honestly I'd have been perfectly happy with Ellie knowing how to give penicillin from FEDRA school, or Joel being conscious enough to help her (he'd surely know how at this point in his life) and the suspense being whether he was ambulatory. He would be concerned about the people she got it from, which they could fight about, and be mentally trying to get himself functional.
@@DrHopeSickNotes would an adrenaline rush from fighting for your life be able to build enough blood pressure to power through septic shock, or is that just Holly Wood?
That Surfshark transition was genius, I am not even mad. 🤣
Thank you, I'm a natural at this
I had no choice but to listen to it as a reward for the smoothness of that transition.
"Nice one Joel". That made me LOL!
Yeah that clip out of context of me celebrating a stabbing might get me struck off :)
The local injection was something I really wanted to hear your response to, with limited knowledge it makes sense to me that Ellie did it, and it's probably what I would do in the same situation, but great to hear about the specifics.
Yeh I wish I knew more; I had a quick browse online after the show and appears we can give some antibiotics subcutaneously (when we can't get IV access) but this is very different to injecting a wound infection! And there was also an article that we can inject antibiotics into abscess when they are difficult to drain. So actually probably would have benefited Joel.
The main issue that.I didn't hammer home enough was that two doses isn't a lot. You'd expect him to need at least 3 - 4 doses a day for 3-5 days IV and then step down oral antibiotics for 2 weeks.
@@DrHopeSickNotes Is 1 bottle really just 1 shot? I figured you would use one bottle for like a week's worth of doses. Are there larger bottles like this, or do you usually use up an entire bottle for one injection?
@@holysecret2 I imagine it has to be 1 bottle = 1 shot, because once you break open a large bottle, it's not sterile.
But that's just how I imagine things work, I'm not a doctor and don't claim to know for sure.
@@holysecret2 Perhaps, but also remember Ellie is no expert. She doesn't know how much to give or where to inject it. So she just puts as much into the syringe that "looks about right" for a 14 year old girl who has no experience. She has no idea that the bottle is no longer sterile. If it even occurred to her, she would probably think hey this stuff kills germs, right?
@@VadBlackwood not a doctor but I do weekly subcutaneous injections and can safely reuse a vial so long as I rub an alcohol wipe over the rubber stopper every single time - the rubber sorta closes back up around where the needle went in, my needles are all new, and I'm only using it for myself so it's not a big deal.
Bella Ramsey managed to upstage Pedro Pascal in the acting stakes in a lot of episodes in this series, we know Pedro is a great actor but damn does Bella deserve an award for her acting in this
Ed man.... you paused it at the wrong time! When she stops and he says "It's me babygirl, you're safe". That is one of the deepest and most moving of the whole season.
Yeh that whole last scene was 😭
Yeah, I wanted to watch a commentary to see if someone else was as wrecked as I was over the "baby girl" moment. 😢
@@rebekahkoretoff6480 I think I mostly kept it together until the 'baby girl' line and then cried. Wow.
@@DrHopeSickNotes I really wanted to see your reaction to "babygirl I got you"
Cat break definitely needed after watching this episode
I agree! Twas a crucial cat break
@Dr Hope's Sick Notes we live for that cat content 🐈
As someone who reads a lot of Medal of Honor or Victoria Cross citations, “went into beast mode” definitely has to be the medical term for that blend of adrenaline & will power to accomplish seemingly impossible feats.
I've never gone into septic shock, but I've had a few surgeries that required I be under a general anaesthetic. I warn the medical staff because when I wake up, my brain only knows that I've been hurt and I don't know where I am. I *will* try to get up and leave, and I am willing to fight anyone who tries to stop me. (This is apparently common enough that when I tell them I'm prone to do this, they just say, it's okay we can handle that.)
Not only am I looking forward to you covering the medical stuff in episode 9, I’m also interested in your evaluation of the ethics of both the fireflies and Joel regarding what happens in that episode
Me, watching this intro again: Oh, I just realized what venison, elk and rabbit is code for
Doctor: *explains rabbit poisoning* So they need more than just really lean meat, they need something with fat as well
Me: *looks at camera*
THANK YOU for not critisising Ellie when she injected the antibiotics straight into the wound. She's a 14 year old girls who's lived a very sheltered life in a post apocalyptic dystopian society. She would have absolutely no idea what to do and putting it into the wound was a totally understandable guess. I have seen other youtubers critisise her actions in this scene, without taking into account that shes LITERALLY 14 YEARS OLD WITH NO MEDICAL TRAINING. Most people I know wouldn't be able to inject a needle at all!
The part where Joel nearly pops off the guy's kneecap turned my stomach. This whole episode is trauma upon trauma. Emotional and physical.
NGL, Joel calling Ellie "baby girl" absolutely broke me in this episode. Pedro and Bella absolutely fuckin killed it.
The idea that Joel was hallucinating the whe time is hysterical 🤣 Thank you so much for covering this medical scene!
Actual comment on the video: Can't wait for the rapid shot trauma diagnosis on the last episode.
Oooo is there one worth doing?! Nice!
I don't know what I've enjoyed more The Last of Us or Dr. Hope's Sick Notes about it! The fact that you're clearly a fan of the show makes the medical critique a fun addition to the story, I'm really looking forward to your review of the finale.
Oh and don't worry about making the last episode review to long, I think everyone will agree, we would like to see all your reactions
Hearing you talk about S. Aureus and Pseudomonas gave me flashbacks to Cells at Work.
Yeh I was going to put Cells at Work bacteria on screen when I mentioned them, but then it might have been a confusing reference for some people! I want to get back to that show again, loads more episodes to cover
@@DrHopeSickNotes Ooh, please do! We love your 'Cells at Work' coverage! 🎉
I'm surprised the eating people thing didn't come up because I think that has some medical issues behind it although not sure as I have never done it myself
Maybe he’s doing a cannibalism special with that and Yellowjackets?
Got a lump in my throat when he called her "baby girl". What a show.
I once heard about a guy who ate a polar bear or Polar bear liver and died almost immediately because it was like 100% protein. Could've been an urban legend but your explanation of eating just rabbit made me think. This episode was brutal but Bella deserves every acting award imaginable. I love your reactions!
Thanks for the comment! Yeh I think polar bear livers have lots of vitamin A; which is fat soluble so difficult for your kidneys to get rid of toxic levels; so you effectively get an overdose. I learnt that from watching QI
When you're in for medical notes, but surrender to the feels. Good job, doctor!
nothing breaks me quite like the moment where ellie leaves the burning building and joel goes to comfort her and she just. struggles. the hurt, this inability to trust, the utter breaking down. it's definitely the most raw scene in the entire show. then she fully realizes that it's him and that she's safe and she just realizes that he's home and that it's all over and it's the most beautiful thing in all of television
I have thought of all the deficiencies in these peoples' diets too. Unless they were grinding up bones, they weren't getting any calcium either. No B vitamins, no carbs, no Vit A or C. If they don't have rabbit poisoning, they have scurvy or nutritional secondary hyperparathyroidism
@@RogueDemagogue I take it you aren't a registered dietitian from this comment.
Tha ad segue was top tier audacity. *chef's kiss*
Great vid as always Doc!
For pseudomonis my hospital will still just prescribe vinegar washes, which may have been easier for ellie to find
Good episode. From how fast Joel recovered I wondered if that antibiotic had some adrenaline in it lol. I did find it odd you skipped the part where Joel stabbed the guy in the knee.
Yeh I actually talked about the knee injury, but cut it in the edit as the video was getting so long; likely ruptured the quadriceps tendon and left his patella all flappy.
@@DrHopeSickNotes In all fairness, that guy wasn't so much worried about his knee injury after Joel stabbed him in the chest.
Yeah, I also always feel like I could use some peaceful time with a kitty after watching this scene
“These people need some other form of food” well good news: they weren’t just eating venison
The season finale’s major plot point is contingent upon a desire to embark on a medical venture that I regarded as highly dubious as a layperson. Since I don’t want to spoil, I won’t say more than is necessary to frame my question to Dr. Hope: what is the likely utility of this plan medically? I grant you that it’s dealing with a unique case in a worldwide pandemic of a fictional fantasy fungal disease. But given all of the context that is available, including what little medical materials and expertise would have survived into the post-apocalypse, what’s your best ballpark estimate that this experiment would have been worth what it cost?
Man I love you’re videos and your medical breakdowns (super interesting!), but honestly I’d also just love to see more of your general reactions to the rest of the episode! I’m sure I speak for other supporters of your channel, but we’re here for you yourself, as well as your medical knowledge! Keep up the good work!
This is the only way I can watch the last episode. Through Dr. Hope. Just too emotional, but I'll do it when I feel I can.
Dr. Hope's advice every time: you're going to need a hospital and a doctor for this injury...
and he's right!
Realizing that the outdoor scene was filmed before the indoor scene makes tha acting even more impressive.
I'm a little surprised that you didn't mention Ellie's risk of smoke inhalation dangers from being in the fire.
Loved the reaction as always!! I laughed so hard at the delirium and beast-mode parts 🤣🤣🤣🤣
I thought you were going to comment on the cannibalism fact and Kuru disease, the reaction was amazing nevertheless!! 😃😃😃
Thanks for watching! I've never heard of Kuru disease, so I'll check it out
@@DrHopeSickNotes always on the watch for new Sick Notes!! 👍
Kuru disease is similar to "🤪🐄".
@@laylai.3087 Love your use of emojis to describe Mad Cow Disease/BSE! 😂😂😂
@@tamarinmangold1414 It must be the memories of old 00's videos/memes of mad cows all over the Internet 🤣🤣🤣
I've been waiting for this video to get resolution on the injection question. I guess I could have looked it up, but that's what I have Dr. Hope for!
Second question: would the instructions for the penicillin typically be printed on the label?
For next episode I expect a lot of psychology analysis on Joel's actions. If you have anyone experts on psychology around you, I would suggest you to watch last episode with her/him.
Thanks for the tip!
@@DrHopeSickNotes ur welcome 🤗
@@kyihsin2917 Thank you, I will have a look at his channel!
@@kyihsin2917Georgia Dow is also excellent.
16:35 Imagine playing the game man bro u had to constantly sneak attack David and it was one of the creepiest parts of the game .....
And by the way Joel actually sneaks up and stops Ellie in the burning restaurant .......
In the videogame (from what i remember) she would actually feed him and make him drink lots of fluids. She traded 2 deer for a box of penicillin, and a surgical first aid kit. She actually was seen studying a medical book in the vido game.
I believe it was Craig Mazin (the showrunner) who said this is Joel at 10%... imagine how utterly brutal he was when he was younger and healthy!
We see that in episode 9 in the hospital
My father is in his 70s. He started have little seizures from time to time. You can’t tell unless you really pay attention. The doctors say a head in jury from when he was younger could now be causing this so many years later. He was thrown from a horse on a gravel road as a child and had a head injury. He got knocked out playing high school football. He was also a passenger in a fatal car accident as a middle schooler and was knocked out. He came to before anyone else and flagged down help. He was more injured than anyone realized until after they got everyone else to the hospital. (His brother was driving and they were hit head on by a drunk driver. The drunk driver was the one that died, but several of my dad’s brothers were injured, though they all recovered.) would these incidents have waited over 50 years to start causing seizures?
I can’t believe it’s the the discussion of eating RABBITS that we focus on for this episode 😂
@@RogueDemagogue The problem with eating brains is that’s how you get all kinds of fun prion diseases and then we’ve got a WHOLE DIFFERENT kind of zombie problem
Cant wait for the next episode especially the morality aspect!
People who have been in situations where they've had to eat other people have had the trouble where the people they eat have so little fat by that point the person eating them has got rabbit poisoning.
Fun factoid: The guy that's beside the dude ready to chop up Ellie is the voice actor of Joel in the game!
That delirium bit was so funny🤣 I’ve been crying for a few hours about my chronic illness and it made me laugh so thank you
i dig this, ive seem other medical channels, but your actually watching the show with some investment in the characters and that mate, thats how u get a new subscriber
1:12 "These people need another source of fat or carbohydrates."
Oh, I think they have that covered
Omg, now i have a second thought about that scene of Joel killing those 2 guys🤣 You're right, he may be hallucinating🤣
I am a horse rider and have had a number of falls resulting in injuries - two broken wrists and potentally bruised and/or broken ribs (never saw the Dr. but probably should have considering the pain I was in for months afterwards)
The 2nd time I broke my wrist, although not suffering a concussion (that I know of) I still experienced many of those same symptoms Ellie did - I started sweating profusely, ringing in my ears and everything else sounded like I was underwater. My vision went totally black and white and I couldn't see any colour. I was very dizzy nauseous. Still - I got back on the horse and kept riding for another 15 minutes until I dismounted and took my glove off, realising how swollen my wrist had become in that time! The feeling of absolute confusion and dread that comes after being thrown off a horse is one in a million. Nothing else like it.
David's right have man is Troy Baker who played Joel in the game
It is crazy how yesterday I was wondering when we will see you go again Doc 😁
How much adrenaline do you think his body would pump if he thought of her as his daughter and then felt she was in danger? would enough course to get him to his feet? I am also wondering once the adrenaline wears off if he would not just collapse unconscious
That was interesting information about re-opening the wound in cases of bad infection like that. It's not something that seems intuitive, so I will definitely have to file that away in case I ever have need of that type of treatment in an apocalyptic scenario.
This channel is flawless!
My first ever compliment off a potato!
15:57 There is the reaction I was waiting for 😂 David is the most messed up enemy in the The Last of Us ....
"These people need some other diet than rabbits" - oh they are getting it alright...
With that moustache you sort of look like Pedro as Joel
I recognize staphylococcus aureus from our favourite: CELLS AT WORK! (Also from a recent bout of osteomyelitis--long story.)
Oh god. Hope you are okay mate
Thank you for doing these. I always enjoy your videos.
Aww. Daisy :)
'stache is mad classy, doc
Still not a fan of the moustache, but can never complain about new episodes from Dr. Hope, as they're always excellent!!!
Thanks mate! Don't worry the tach has left the building!
this had to be the best review of this series yet, oof, you do know your stuff lol
in an apocalypse a doctor could be your best hope or your worst enemy, with their knowledge of the human body! LOL one thing for sure if this does happen in real life, I'm head to the UK to meet up with him!
Was waitting for this 8th ep reaction!
Thank you! I can see why, best episode of the season.... so far
Is human IV penicillin cloudy? I was taught in vet tech/nurse school that the only non-clear solution that should go IV is propofol. And while not all clear things can go IV either, cloudy solutions should be IM.
No comment about the knee stab? Probably not a life-threatening injury, but I always wondered just how badly that would mess a person up.
I'm gonna go to emt school this fall, and your explanation of medical terms is really helping me out. I'm taking notes!
That was a long needle. I wonder if it would have gone into the peritoneum and been absorbed that way.
I wondered what your opinion would be about their cannibalism. What type of diseases might be transmitted. Their leader was truly the real villain of the story so far, I'm happy he got his karma served. You are doing a fantastic job, I love the array of human emotions on your face as much as the medical info. It's a human bonding experience.
I’m a doctor as well. I don’t think cannibalism would be a problem health-wise, you would probably want to avoid eating the nervous system like the brain and spinal cord to minimize the risk of getting a prion disease (like kuru or other transmissible spongiform encephalopathies like (variant) Creutzfeld Jakob disease, Gerstmann Sträussler Scheinker syndrome and fatal insomnia, although all of these are extremely rare but you wouldn’t want to eat the body of somebody who has them, since they are transmitted through misfolded proteins (prions) which in turn cause other proteins to misfold and can’t be destroyed by cooking. Also, I know eating some organs like a polar bear’s liver causes deadly vitamin A poisoning, but I’m not sure if it would be safe to eat a human liver. Ritualistic cannibalism has been a part of various human cultures over the course of history, and has also been used as a last resort in periods of extreme famine (for an interesting, if not horrifying, event which features cannibalism, google Donner party)
I also was curious about cannibalism. My husband works at the medical book store at the campus and each year after the students had their first human dissection a lot of them talks about how creepy it was that they got super hungry during the dissection...
@@Nightraven26 Thank you so much for your valuable insights!
@@RogueDemagogue Alive was such a good movie based on that story.
@@Telamond I've never heard that before, that is really interesting. There is so much we don't know yet about how the human mind works.
yea so many shows give out head wounds like candy lol
I've really enjoyed these reactions and reviews a lot. I hope you do season 2 when it comes out and maybe even check out Hannibal at some point to analyze.
As always Doc, a stellar review of the injuries to help educate the rest of us non-medical people :D
The show by this point is having to skip over MASSIVE amounts of story contained in the game to shoehorn a TV show in. TLOU1 in the game while the show did it a credit in so many ways, the show also cut incredible amounts of story. The cannibalism aspect here you didnt even go in to as well. The game expands a lot on this section of the story. But the character that played David the preacher did a 15/10 job. He came off as perfect according to the game and the director stuck HARD in many places right to the game. The acting all around for what they did allow was BRILLIANT.
I am freaking a bit about show 9. What else will the show change but also have to cut?
09:15 So regarding the whole "Stay awake, stay with me!" thing in movies (not losing consciousness when near death), is that actually a thing (medically) or not?
I know for the PATIENT they may want to stay conscious as they may not know if they'll ever wake up again. But medically is this the best thing for them? Considering you're probably losing consciousness for a reason (to go into low power mode).
Therefore, is there any medical benefit to forcing the patient to remain conscious when near death, or are you more focused on just keeping their vitals going? (Pulse etc)
I'm not a doctor so I dont' know about all situations in emergency medicine. I do know that there are some situations where telling the person to relax can be unhelpful, specifically rescuing people who are suffering from hypothermia.
When emergency rescuers are airlifting people out of cold water (like if they have been floating in lifejackets after a ship sank), rescuers used to reassure the person when they got to the helicopter "it's okay, we've got you, you're safe now". The person would relax, their blood pressure would drop, and they would die.
Now that is known, the best practice when rescuing people is to say "we're going to help you but we need you to keep fighting".
Adrenaline raises blood pressure and makes you breathe more deeply. When you sleep, your blood pressure drops and your breathing is suppressed. In some cases being afraid and knowing that you could die if you relax can help keep you alive, but it depends on the type of emergency. For a lot of illnesses rest and sleep is what you need so you can heal, and stress is unhelpful. I'm not sure whether just "try to stay concious" is ever helpful, but it might be in some cases.
Loving the stache
You skipped over the part where Joel drives a knife into the guy’s tied to the chair leg.
From a doctor's POV since we know they aren't eating deer&rabbit - can humans get a form of mad cow disease?
Bella Ramsey deserves an Emmy for her performance!
I was waiting if he will tackle about Joel stabbing that guy's kneecap, if it's that easy to pop it off
I think he ruptured the quadriceps and left the patella a-dangling.
Was waiting for the dietary rundown on only eating human meat hahaha
Yes, don’t fall asleep Joel. By all means, don’t fall asleep while lying down in a dimly lit quiet place....
Skipped right over the cannibalism eh... now I’m no doctor, but it seems to me, that cannibalism, if you set aside the prion related dangers and socially stigmatizing ethical issues, it seems to me, that cannibalism is a great way to avoid rabbit poisoning... 🐇
I’m allergic to amoxicillin and so my doctors don’t use penicillin for me. What should I try to look for if I’m in the apocalypse, besides giving penicillin the old college try?! 😂
that penicillin really did the trick, lmao
Whoa if Jack Quaid and Neil Patrick Harris baby here ya go 😂👀
Also wouldn't the antibiotic formulation in this case be most effectively administered via IM injection, especially considering the nature of Joel's condition? In cases such as these involving severe secondary infection and systemic symptoms, isn't it not uncommon to administer doses of certain antibiotics via IM injection before following up with a course of oral and/or IV antibiotics? Essentially this delivers a large dose that can be rapidly absorbed and metabolized to kickstart the fight before the following consistent treatment with more reasonable therapeutic doses.
Sorry if my phrasing is a little screwy right now, I'm running on very little sleep with chronic insomnia so I'm a kinda "bleh" and perhaps a little slap-happy right now...
Now I just need to see your reaction to the game's original version of Joel's big injury and how he went off in town hahaha
Hey Dr Hope! Could you make a video explaining Toxic Shock Syndrome? So many videos on Tiktok are demonising tampon use and claiming it’s a really common condition, and I am very confused.
Billions of women around the world use tampons every month. No, it's not actually a really common condition.
@@Nse204 it is common.
This was amazing I had so many questions about all of this. Thank you so much lol
I'm only 2 years into med school, at what semester do we learn about this condition of "going beast mode"?
Wonder if you can do Code Black next. It would be really interesting how it is handled in UK if it happens that you have more patients than doctors/nurses.
Given that this is in the US, isn't there a more than decent chance that this is Penicillin G benzathine which really should not go in a vein?
It's a bit funny that TV show Ellie kills video game Joel with the cleaver.