What doctors don't know about the drugs they prescribe | Ben Goldacre

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  • Опубліковано 26 вер 2012
  • When a new drug gets tested, the results of the trials should be published for the rest of the medical world -- except much of the time, negative or inconclusive findings go unreported, leaving doctors and researchers in the dark. In this impassioned talk, Ben Goldacre explains why these unreported instances of negative data are especially misleading and dangerous.
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  • Наука та технологія

КОМЕНТАРІ • 1 тис.

  • @mattgilbert7347
    @mattgilbert7347 7 років тому +309

    Somewhere along the line we lost sight of what science is and instead have focused on what sells.

    • @ericbartol
      @ericbartol 6 років тому +8

      Matt Gilbert It is the money. When money encounters science, or politics, or religion, or anything else, things get turned away from where they should be headed. Money may be the root of all evil, as the saying goes, but we all know that money is a rampant force in everything these days.

    • @petitio_principii
      @petitio_principii 6 років тому +2

      It's not just money. It will happen in other scientific areas without the evil "big pharma" interests to skew results into false positives. If you find that men are more likely than women to hit the car horn when someone cuts in front of them, you're more likely to be published than if you had found it's about the same.

    • @olaolu10
      @olaolu10 5 років тому

      Damn straight

    • @pagogo84
      @pagogo84 5 років тому

      Couldn't have said it any better!

    • @trafficjon400
      @trafficjon400 4 роки тому

      Only human. stinks and man will out smart him self

  • @RobertDePinto
    @RobertDePinto 2 роки тому +132

    We need him now. More than ever. So many are fooled by what science is, what peer review means, and the publishing system.

    • @Madmarsha
      @Madmarsha 2 роки тому +8

      I'm surprised people are allowed to say this these days with all the suppression going on.

    • @therealdutchidiot
      @therealdutchidiot 2 роки тому +1

      @@Madmarsha True. Antivaxxers have been trying to silence the data. Just like Exxon did back in the day, which is a problem up to this day. The publishing structure is just a sidetrack. Keep in mind this talk is TEN years old. And yes, medicine in the US (FDA is US only) is bonkers, it isn't trusted anywhere near the world stage.

    • @Coneman3
      @Coneman3 Рік тому

      You’re not wrong. I posted a video like this on a WhatsApp group, got ejected from the group, and contacted by police after I texted the person. We are turning into a corrupt police state. It’s like 1984 come true!

    • @billybandyk0720
      @billybandyk0720 Рік тому +1

      ​@@Madmarsha More like "oppression" & "censorship" than "suppression" but I got the gist.

    • @humanresetproject
      @humanresetproject 7 місяців тому

      AMEN

  • @rhondaweber1908
    @rhondaweber1908 6 років тому +282

    It's more than not publishing negative results, it's suppressing results.

    • @naberrrrr5678
      @naberrrrr5678 5 років тому +4

      exactly...

    • @r.b.4611
      @r.b.4611 5 років тому +4

      If there's a culture of publishing negative results it will be harder to suppress results.

    • @conniegomez1321
      @conniegomez1321 4 роки тому +13

      Fife and others had Cancer CURES in the 1930's. They had their research labs destroyed and facts trashed!!!!

    • @s104118
      @s104118 4 роки тому +5

      It's not just negative results that are suppressed.
      But also traditional/natural approaches.
      Approaches used when there was more health. (And very few heart attacks.)
      It all means sickness benefits is crowded.
      But health benefits is a good opportunity.

    • @trafficjon400
      @trafficjon400 3 роки тому

      @Wilson Pablo care about what?

  • @salimzwein
    @salimzwein 10 років тому +232

    this guy is a hero

    • @MultiChrisjb
      @MultiChrisjb 3 роки тому +6

      And amazing hair!

    • @brendansmyth5053
      @brendansmyth5053 5 місяців тому +1

      Sure is mate 👍🏻👍🏻🇦🇺

    • @celiacresswell6909
      @celiacresswell6909 20 днів тому

      @@brendansmyth5053vanished during covid - my working hypothesis: - cowardy custard

  • @SilverShadow02
    @SilverShadow02 11 років тому +37

    The statement that 100,000 people died as a result of the testing of one drug literally had me crying. This is a horrible thing that is happening.

    • @Dragon-Slay3r
      @Dragon-Slay3r 6 місяців тому

      Testing died from cancer and agent 47 had plenty of 💔 covers to cover it 😂

    • @richardsackler7627
      @richardsackler7627 5 місяців тому

      People have no idea how big of a scumbag some doctors are. No clue.

  • @laurawillingham1965
    @laurawillingham1965 4 роки тому +41

    And as of September 2019, it still hasn't been "fixed", sadly.

    • @onewiselady6412
      @onewiselady6412 4 роки тому +5

      Laura Willingham
      No it’s has not
      I’m so bloody mad
      My husband died by suicide 4 years ago and was prescribed ZOLOFT - one of the worst

    • @trafficjon400
      @trafficjon400 3 роки тому +2

      What makes ya think its going too? 2020

    • @julianshepherd2038
      @julianshepherd2038 2 роки тому +3

      Not yet 7/21

    • @laurawillingham1965
      @laurawillingham1965 2 роки тому +3

      @@onewiselady6412 I am so very sorry for your and your family's loss. I can't imagine how difficult it must be for you all. I pray comfort and strength as you continue to walk through this very sad loss.

    • @onewiselady6412
      @onewiselady6412 2 роки тому +2

      @@laurawillingham1965 wow
      Thankyou for such a lovely comment ❤️

  • @nathanieldoromal6904
    @nathanieldoromal6904 3 роки тому +28

    Hiding information and research bias has taken on untold heights with COVID-19.

  • @obiektywemlibby3449
    @obiektywemlibby3449 9 років тому +90

    oh well... we all live in the world full of corruption. I'm glad not everyone is blind...

  • @wdtony
    @wdtony 11 років тому +40

    An SSRI adverse reaction almost killed me in 2006. Serotonin Syndrome....but my doctor wanted to blame an "underlying condition" at first. Now I know high numbers of people have died or suffered brain damage from these prescription drugs. Yet, the marketed induced paradigm is that these drugs are safe.

    • @beannamated
      @beannamated 2 роки тому +6

      @wdtony. How are you doing today? I was disabled by an SSRI and know many who have also had horrible experiences, permanent disabilities including brain damage, and many who died. WMD.
      I hope you are doing ok.

    • @wdtony
      @wdtony Рік тому +1

      @@beannamated
      Better than the first 3 years. But still have major damage to my CNS and Blood Brain Barrier.

    • @themanisright12345
      @themanisright12345 Рік тому

      Psychiatry is fucking evil.

    • @Kameron-The-Crafter
      @Kameron-The-Crafter Рік тому +1

      @@beannamated I'm so sorry. I'm thinking of dropping the rest of my meds. I dropped lamprogine. Because I kept forgetting things. I kept losing balance, and getting severe headaches. And that's not including sleep issues.

  • @pavel0900
    @pavel0900 2 роки тому +8

    Even more relevant today than 9 years ago when this video came out

  • @conodeen3588
    @conodeen3588 5 років тому +87

    This is so very important! Replication or REPEATABILITY is one of the cornerstones of science. I’m a PhD student in geoscience/engineering and I find it so frustrating when I read papers and am not able to replicate even elementary results in the lab. Unfortunately, full scale replication is a very technically complex, time consuming, and expensive process. It is going to be to be impossible to do replication without heavy incentives. And currently incentives are basically a BIG ZERO! All of the emphasis is on novelty! We need to fix this across the board. Not just in medicine.
    (And no, this doesn’t excuse people for being anti-science! Plenty of great work out there.)

    • @laurawillingham1965
      @laurawillingham1965 4 роки тому +12

      The problem is the fact that each person is genetically and epigeneticly different. Foods, environmental exposures such as mold/metals/chemicals, birth and infancy factors such as feedings, conditions in the womb, allergens/sensitivities/blood types, and social situations all play a massive role in addition to genetics. Trials never consider those variables, sadly. Microbiome is crucial and is highly individualized. Sadly, the approach of the standard medical community completely disregards the most important aspect of our bodies, the digestive system. It indeed does matter. Even Hippocrates knew that. Functional Medicine has far more of a clue than our standard medical community.

    • @sawtoothiandi
      @sawtoothiandi 4 роки тому +1

      hello, could you please have a look at this study and tell me what you think, thanks
      Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin
      www.ncbi.nlm.nih.gov/pmc/articles/PMC3085190/

    • @Alphacentauri819
      @Alphacentauri819 3 роки тому +2

      Laura Willingham yes, yes, yes!!!! So glad to read this comment... I actually had to recheck (username) that i hadn’t written it at another time 😂
      I’ve written very similar comments.
      I used to work in a hospital... I remember my epidemiology class lit something in me, I had the planting of the idea that “results” could really be anything.
      Everyone is an individual in multifaceted ways. We can’t ever test/study each type with every pharmaceutical, with every potential diet, environment, genetic makeup and the potential billion combos.
      I’ve said for a while, we are all guinea pigs. Always. We really never know.
      Additionally, there ARE people who are epigenetically susceptible to many environmental triggers, INCLUDING vaccines. Not that vaccines will damage all of them. But that they are the canaries in the coal mine...and we aren’t acting as if that’s possible .

    • @trafficjon400
      @trafficjon400 3 роки тому +1

      @@sawtoothiandi 5-6 year old video and your high standards don't mind ?

    • @sawtoothiandi
      @sawtoothiandi 3 роки тому +2

      @@trafficjon400 sorry, i dont understand what you mean?

  • @deejay8ch
    @deejay8ch 2 роки тому +39

    This video is more valid now than ever. Thank you Bret Weinstein for directing me to it

  • @gr8pillock
    @gr8pillock 11 років тому +49

    Still one of my absolute favorite of ALL the TedTalks I've seen. Just a genius. A freakin hero.

    • @trafficjon400
      @trafficjon400 3 роки тому +1

      Hero for what by showing fear is real and he knows he a pee in a pot and people laughing at him like he's crazy. worse 2020 and on. We see Doctor it's our fault these days.

    • @jasonbourne5142
      @jasonbourne5142 2 роки тому

      Youre a left wing nut

    • @beannamated
      @beannamated 2 роки тому +1

      @@trafficjon400 if that's all you got out of it, please rewatch.

    • @trafficjon400
      @trafficjon400 2 роки тому +1

      @@beannamated My Comments below might say a little more. a little of it . he is a sharp cooky .

  • @andy4an
    @andy4an 10 років тому +32

    This guys has another great TED called "Ben Goldacre: Battling Bad Science"

  • @maheshsnair1
    @maheshsnair1 Рік тому +5

    One of the most important videos on youtube.

  • @ZER0--
    @ZER0-- 3 роки тому +30

    What I found out recently shocked me. When testing a drug, or other substances, on rats the researchers can use different types of rats which can lead to different results. I was quite surprised as it can be used to give you more favourable results.

    • @adriangodoy4610
      @adriangodoy4610 2 роки тому +5

      you can try multiple animals until you find the best to actually conduct the studies

    • @alexforget
      @alexforget 2 роки тому +6

      Those rat has very high replication of cells, which means that they recover easily from damage done by drugs. The tradeoff is that the rats all die of cancer (lots of cell replication)
      The rats are breaded to have those characteristics, which means that drugs tested on them show way less damage and help the cosmetics and pharma industry push those products to market faster.
      For sure, the lab will keep on buying the ’good’ rats that produce the results they want.

    • @staceystrukel1917
      @staceystrukel1917 2 роки тому +4

      They also remove the test subjects, rat's, if they don't get the result they want it all of them.

    • @Steel9k
      @Steel9k Рік тому

      At vaccine testing, using placebo is not necessary.

  • @frankyduks
    @frankyduks 8 років тому +188

    this guy's got balls

    • @thatleftypapist8008
      @thatleftypapist8008 8 років тому +7

      How so? A lot of people who care about evidence-based medicine have been vocal on this issue.

    • @mattw9011
      @mattw9011 7 років тому +6

      Truth is not about having the balls, it's about having the respect for what you do and what you believe in so that others know the truth. Nothing about having balls.

    • @kassi4837
      @kassi4837 6 років тому +11

      Franky Duks he stands up to dragons , metaphorically speaking and spares no field his arguments. I am thankful for every day he lives.

    • @mrbroderick8581
      @mrbroderick8581 5 років тому

      He doesn’t. He won’t speak out about the PACE trial because his boss was the architect Simon Wessley

    • @cowswirl
      @cowswirl 3 роки тому

      medicine balls

  • @dragonballjiujitsu
    @dragonballjiujitsu 11 років тому +16

    Its nice to see someone with credibility saying what me and others have been saying for 20+ years.

    • @Steel9k
      @Steel9k Рік тому +1

      You and others had kind of the sam credibility, actually.
      Stupid ones didnt understand you. Dont understand life around them...

  • @kissykrissy33
    @kissykrissy33 2 роки тому +3

    Checking in during the middle of 2021, it's fascinating the foreshadowing we have missed

  • @osteopathichomeopathicking6154

    Hard to believe TED published this.

  • @channandlerb4002
    @channandlerb4002 5 років тому +6

    I completely agree with speaker Ben Goldacre and his informational talk on the issue of publication bias. Publication bias can be especially dangerous when viewed through the lens of medical ethics.
    When doctors look at prescribing medications, especially medications that are new to the market, most of them strive to be as informed as possible about the medication’s effectiveness, benefits, and risks. They operate under the premise of non-maleficence - to “do-no-harm” - and yet despite their best efforts, if the information that they need is not published, they will unintentionally have a skewed view of the medication they prescribe. This is worrying considering that the trials with negative results that do not get published are likely to be the most transparent and informational resource about the medication’s negative side effects. Even in the tragic situation that the medication’s risky benefits outweigh all the negative side effects, doctors are ill-equipped to monitor their patients for the appropriate warning signs of any serious complications, all because these journals favor positive results over negative.
    Publication bias also makes it impossible for doctors to protect a patient’s autonomy. Doctors strive to abide by the ethical principle of autonomy, where it is their duty to provide each patient with the best chance of making well-informed decisions about their health care. However, if accurate, transparent information is not available to inform a doctor of a medication’s risks and side effects, they in turn cannot give their patients a clear, well-informed choice either.
    While I understand the excitement of positive test results and the forward momentum of innovation they provide to the scientific community, our progress is meaningless if we ever let our strive for discovery outpace our sense of humanity.

  • @dlpogge
    @dlpogge 4 роки тому +15

    “Every great cause begins as a movement, becomes a business, and eventually degenerates into a racket.”
    ― Eric Hoffer, The Temper of Our Time. So it is with modern medicine.

  • @bluecafe509
    @bluecafe509 11 років тому +9

    This has been going on for years. I had a professor whose work, which was damning to the testing industry (academic testing), could never get his research published in the more popular journals. He was widely regarded as an authority in his field, but journal gatekeepers are free to accept or reject the research they choose.
    We now know that tests do not predict future performance in school and that the best predictor of future academic success is indeed past level of academic attainment.

  • @robbiemc9253
    @robbiemc9253 3 роки тому +19

    Thank you for sharing such an insightful talk, it's intriguing to see professional bodies standing up and sharing the truth with regards to suppressed research findings and more 👏

  • @cardiacmyxoma4073
    @cardiacmyxoma4073 5 років тому +36

    I told my mom (a cardiologist) and she said that she knew this was going on. That’s why she tries to prescribe alternatives to medication.

    • @antuanclamaran1205
      @antuanclamaran1205 4 роки тому +2

      What kind of alternatives to medication ?

    • @GreenLakes1
      @GreenLakes1 4 роки тому +3

      @@antuanclamaran1205 water fasting, eating better/cleaner etc, i'm going to be a nurse practitioner when I get older.

    • @antuanclamaran1205
      @antuanclamaran1205 4 роки тому +2

      @@GreenLakes1 Eating healthier food + Exercising + Eating less (if overweight) are always good, especially if you do all three.

    • @GreenLakes1
      @GreenLakes1 4 роки тому +6

      Antuan Clamaran Exactly, which is why I don’t get it when people say doctors try to “kill us” when I was younger I got diagnosed with pre diabetes and the doctor told me to eat once a day, exercise and stay away from fruits and try to eat as many vegetables as I can and prescribed 200mg of metformin , following her orders I lost 40lbs and got rid of the pre diabetes, the only doctors who are actually “out to get us” are the ones who prescribe medications every visit.

    • @antuanclamaran1205
      @antuanclamaran1205 4 роки тому +8

      @@GreenLakes1 It varies wildly, from doctor to doctor, from country to country etc. Since governments aren't doing a great job caring for the people's health, it's up to each individual to educate himself and care for his own health.

  • @basskick666
    @basskick666 3 роки тому +12

    To all the people who think this video is in favour of untested herbal medicine here is a quote from Ben Goldacre himself "Just just because there are flaws in aircraft design that doesn't mean flying carpets exist."

  • @Primalxbeast
    @Primalxbeast 11 років тому +15

    I watched some of his other videos, and he does seem like a nice guy, but I've had mental health problem all of my life, and I'm 41 now so I've encountered many psychiatrists, and they tend to be a very nasty lot. If you'd ever been in psych wards, you'd know that shrinks treat patients like criminals. No other doctors treat patients as if they're to blame for their illnesses.

    • @beannamated
      @beannamated 2 роки тому +2

      If you aren't familiar with Mad in America by Robert Whitaker, it's a good place to start regarding this subject and connect with others of like mind and experience.

  • @adamlees1720
    @adamlees1720 10 років тому +38

    I'm a pharmacy student, well aware of the multi-tiered criticism of SSRIs. I was having some trouble with mental health and after practically begging with a psychiatrist, and staff at my uni, i still am being forced by the university to follow his orders and take a course of citalopram. It's been incredibly stressful, i feel completely impotent in my own care and the credibility i've worked hard for has been completely ignored. I'm going to have to lie to the mental health staff and tell them i'm taking my medication, i feel dishonest and feel that my care has been completely compromised by this, my depression and self-esteem has never been worse. I understand there are billions (even trillions) of pounds at stake for the pharmaceutical companies, but I wonder if they have some excuse for their behaviour, or if they simply don't think about it. They deserve to have their noses rubbed in every life they've affected or cost

    • @TeaEmess
      @TeaEmess 9 років тому +6

      The excuse is "there are billions (even trillions) of pounds at stake for the pharmaceutical companies." It justifies everything they do. Truth doesn't matter when money is at stake.

    • @jheijmans9282
      @jheijmans9282 9 років тому +1

      www.ssristories.net

    • @GerardGibney3
      @GerardGibney3 7 років тому +4

      they dont care at all.

    • @JB-lj4dm
      @JB-lj4dm 6 років тому +4

      I was forced antipsychotic drug and caused breast enlargements and weight gain

    • @JB-lj4dm
      @JB-lj4dm 6 років тому +2

      I was forced antipsychotic drug and caused breast enlargements and weight gain

  • @KanyeT1306
    @KanyeT1306 2 роки тому +6

    More relevant over the past two years than any time previously.
    This entire pandemic has been a complete failure of the medical establishment. They have burnt all credibility that they will never recover with their negligence.

    • @beannamated
      @beannamated 2 роки тому

      🎯🎯🎯. And many people STILL buy into it.

    • @aqilshamil9633
      @aqilshamil9633 Рік тому

      @@beannamated stupid sheeple can't be taught

  • @FunkyMonkeyJunkie302
    @FunkyMonkeyJunkie302 11 років тому +4

    I love this man so much. For so many reasons. I could listen to him speak for days on end.

  • @davidcrawford9026
    @davidcrawford9026 2 роки тому +4

    it's all so clear and plain as day. there is no reason left for all doctors to not know this. They must want to hurt people

  • @prasad_d099
    @prasad_d099 3 роки тому +2

    I searched about this topic because i came across the book death by prescription....people don’t think this is subject of concern unless they affect by this

  • @eloycavazos2816
    @eloycavazos2816 9 років тому +9

    Ben you have the coolness of Marty McFly from Back to the Future and Doctor Who. Keep up the nerdy science!

  • @diableri
    @diableri 11 років тому +4

    Thank you. Keep up the good work. 13 years in Cardiac Research.

  • @consuetabrevis
    @consuetabrevis 6 років тому +2

    thanks man!

  • @BullCricket75
    @BullCricket75 5 років тому +1

    Thank you!

  • @Genesislights
    @Genesislights 3 роки тому +14

    I love science, just can’t trust the scientists sometimes

  • @happyd9733
    @happyd9733 3 роки тому +8

    Bret Weinstein sent me here

  • @MistaTwitch
    @MistaTwitch 2 роки тому

    Great work!

  • @eddiediesel9035
    @eddiediesel9035 4 роки тому +1

    Great speaker.Awesome video.

  • @tapary
    @tapary 11 років тому +4

    Thank you Mr. Goldacre for providing this information. Many people are willing to trust certain institutions/organizations, forgetting that all institutions are susceptible to corruption, whether public or private. I hope that this wakes up millions!

  • @santoshshedge4436
    @santoshshedge4436 4 роки тому +11

    Very true Dr. Ben. This is all due to the 'greed' the pharma industry thrives on. As of today, with the race to develop the COVID-19 vaccine, I'm not sure whether really there would be a 'vaccine' or the immunity wonder within all works the real wonders. Does vaccine really works on viruses?

    • @brunildealbanese9419
      @brunildealbanese9419 2 роки тому

      Vaccines are safe. Covid kills. Depends on the drug

    • @kbit22
      @kbit22 Рік тому

      I recommend the book Good-Bye Germ Theory, it will answer that question.
      Spoiler: No it doesn’t help at all!

  • @sandraslastan8407
    @sandraslastan8407 8 років тому

    Great video!

  • @babsskett2757
    @babsskett2757 2 роки тому

    Wow!! This was very, very interesting. Very infornative. Thank you so much for this video. God bless you.

  • @jazzytunesmusic
    @jazzytunesmusic 9 років тому +38

    After watching this video, it's clear to me that integrity and wisdom are rare values particularly in the field of medicine and corporate world..

    • @jazzytunesmusic
      @jazzytunesmusic 9 років тому +1

      Henry Ibbs and to commit crimes is human, too. Nice logic.

    • @myreddays
      @myreddays 9 років тому +1

      Henry Ibbs Can you be more cynical?

    • @myreddays
      @myreddays 9 років тому +3

      Henry Ibbs These are not errors, Pharmaceutical companies are driven by profit not honesty. And even if we were talking about errors, this is serious stuff. It is at least inappropriate, cynical at the most, to state that 'humans err'.

    • @myreddays
      @myreddays 9 років тому

      Henry Ibbs I took your expression as an exoneration, as if you were downplaying the seriousness of this. It is stills sounds mild to me to call this an 'error', no matter what the dictionary says. Fraud implies an awareness, a deliberateness that is not present in the word 'error' or 'mistake'. In any case, if you agree on the gravity of these crimes, then definitions are secondary.
      And it sounded 'cynical' not naive. Cynicism implies awareness, again, as in fraud. Calling yourself naive really would imply that you are not aware of the main elementary forces the govern society and human behavior. That would be very, very naive. That's why it sounded cynical to me, just because of a matter of probability and common sense.

    • @eggheadeinstein
      @eggheadeinstein 9 років тому +1

      Jazzy, take it from a guy with a family of not just physicians, but surgeons and field specialists. They do not have integrity for their profession. Whereas most professionals know something about everything, and where it came from and why.. I've found the medical field is a lot more about dry procedure. In fact, I developed tinnitus and saw three specialists who said it was not curable. It took me two years but i narrowed it down to certain preservatives, mainly nitrates and phosphates. After a certain amount, my ears act up big time in the form of bad ringing that will last for days. When i first got it i was devouring souvlakis daily, and these are heavily nitrated for restaurant storage. Tell me, why did i figure it out for myself, whereas the word preservative was not even mentioned once as a possibility? Most questions to people in the field are answered with "I don't know." In the case of eye floaters, most opto doctors will tell you the laser doesn't work. And yet, there they are, right on youtube. A guy getting his floaters laser treated before our very eyes. Perhaps the procedure has its risks, perhaps the results vary, but the answer from 90% of their community of professionals is a flat out "Can't be done." The next time a doctor tells you something, don't thank him for his advice, ask him why he feels that way.

  • @54jb3r7
    @54jb3r7 11 років тому +5

    studying medicine, this provided a useful insight. thanks for sharing.

  • @nico5167
    @nico5167 Рік тому +1

    This Ted Talk was both frightening and eye opening to me as a physician in training. When prescribing medicine, we have a duty to patient autonomy and beneficence in each patient encounter. This would mean we present all the information in an unbiased way to allow patients to make informed decisions about their own medical care, as well as illustrate and work with them to weigh the risks and benefits of each procedural avenue. Medical research is the cornerstone that allows us to provide this information for safety and efficacy, but in this lecture we learn that scientific and medical journals, as well as the researchers themselves, may be engaging in unethical scientific practices that unravel this trust between lab and clinic. Ben shares many instances about negative results being suppressed or completely ignored in order to construct a positive outcome for the research team and journal. A positive outcome for a clinical trial can lead to exorbitant financial gain, or status and recognition in the scientific community for the lab and investigators. There is certainly a pressure to find positive results, but here we see that this pressure has overridden the ethical duty of honesty and transparency we so desperately need as physicians. We can only operate with the information we are given, and if negative side effects are suppressed as discussed here, we are by proxy not upholding beneficence ourselves. But what else can we do? How are we supposed to know if the information we trust has been construed for selfish benefit? The COVID-19 vaccination campaign and pandemic policy has unfortunately hindered the community’s trust in both research and medical institutions. This Ted Talk provides reasonable ground for those hesitancies. I myself as a physician in training was skeptical of propaganda and confusing encouragement for vaccine recommendations for young and pregnant individuals when there was not enough data to support efficacy or safety profile. It was easy to see that there may be financial pressures by pharma companies placed upon laboratories or government personnel. I think we may discover that a similar offense as discussed in this talk has occurred in the COVID-19 vaccine story. I think serious penalties need to be in place for labs and journals who are dishonest in their publications and the fault for adverse side effects from prescriptions if not published should not fall at the feet of the physicians.

    • @MK-ih6wp
      @MK-ih6wp Місяць тому

      Please look up Dr. David Healy. He will tell you the truth about how pharma conducts clinical trials.
      Hint: fraud, deception, manipulated statistics, straight up lies dressed up in marketing-speak

  • @WhiteRussianBC
    @WhiteRussianBC 11 років тому +1

    Great speech!

  • @r0mulyni2
    @r0mulyni2 3 роки тому +5

    Amazing was listening to DarkHorse Podcast that brought me here.

  • @chriscoffee9070
    @chriscoffee9070 2 роки тому +21

    This is one of the reasons I avoid doctors and any prescribed drugs and other 'medicine' wherever possible. Unless you're seriously ill there is always a way to treat it with something that comes from nature, by eating more of something, or less of something, or applying something that comes direct from something that grows naturally, or just by ignoring it as best as possible and letting your body fix it, and so being better suited to resist it next time.

    • @bipedalbob
      @bipedalbob 2 роки тому

      That's a very flawed theory, every other animal on the planet suffer from and die from the same illnesses that humans do.
      And the only ones that ever see a doctor are the ones being cared for by humans.

    • @ravindrajogdand3786
      @ravindrajogdand3786 2 роки тому +1

      That's true.

  • @rainbowlifeme
    @rainbowlifeme 3 роки тому +1

    People need to see this

  • @brendanoreilly6917
    @brendanoreilly6917 4 роки тому +1

    Brilliant - thanks.

  • @Plur307
    @Plur307 11 років тому +3

    As a graduate student I must admit my fellow students and I always joke how we wish there was a journal of negative results. We could all have multiple publications already!!!

  • @HappyLife-wv5ms
    @HappyLife-wv5ms 2 роки тому +3

    I wish he had not been silent the past 2 years 😞

    • @celiacresswell6909
      @celiacresswell6909 20 днів тому +1

      He works with Carl hennigan and would know sunetra gupta I think: how could he have stayed silent?

  • @Friemelkubus
    @Friemelkubus 11 років тому

    Thanks for the tip! I'll check it out later.

  • @A1shreyasb
    @A1shreyasb 10 років тому

    great talk! wholeheartedly agree.

  • @jasonmarkson3773
    @jasonmarkson3773 5 років тому +28

    2019 and it has STILL NOT been fixed

    • @trafficjon400
      @trafficjon400 4 роки тому +2

      just get worse more people in agony droping dead and commiting suicide. God love us,

    • @onewiselady6412
      @onewiselady6412 4 роки тому

      Jason Markson - correct
      Took my husband’s life 4 years ago

    • @lt7587
      @lt7587 3 роки тому +1

      @@onewiselady6412 I am so very sorry to hear such tragic news about your husband. This should never have had to happen to him - or to you his wife... We will keep fighting this, it has to stop. Justice must prevail! In the UK since yesterday there has been a small but key change, really a slight improvement: there is now more advice available to GPs about psych drug withdrawal, which means their inability to react to that advice will no longer be based on their ignorance..What they do with that extra long-needed info though is for now down to them, some will do good with it and some perhaps not. It feels like a step in the right direction hopefully..Baby steps.. The fight will not stop however, I want to reassure you of that. Sending you warm thoughts and solidarity ❤

    • @onewiselady6412
      @onewiselady6412 3 роки тому +2

      Louisa Tamburro wow... had forgotten i even wrote that comment here. 11 months feels like a lifetime ago. Thankyou for being so kind ❤️

    • @lt7587
      @lt7587 3 роки тому +1

      @@onewiselady6412 you're so welcome and it's the least that any of us can do to - we're in this together ❤ . Best wishes to you and your family.

  • @fgfanta
    @fgfanta 2 роки тому +3

    Still actual. More actual than ever.

  • @macoxupo
    @macoxupo 11 років тому

    Wery usefull info!!! Thank you very-very much!!!

  • @dannyc8875
    @dannyc8875 5 років тому +1

    Plz, plz, plz never stop. How in the world can u not want this practice to end IMMEDIATELY. And a million thx for exposing this. We need more like u.

  • @john12152
    @john12152 3 роки тому +3

    Weird, they knew things 8 years ago...why are we morons today?

  • @MrInformatician
    @MrInformatician 11 років тому +3

    Rankings of trial sponsors by 'silent trial rate'
    For example, AstraZeneca had 132 trials, of which 26 were silent - their silent trial rate is thus 19.7%.
    On the other hand, Astellas Pharma Inc had 77 trials (of which 58 were silent) making their silent trial rate 75.3%.
    STUDY:
    Huser V, Cimino JJ (2013) Linking ClinicalTrials.gov and PubMed to Track Results of Interventional Human Clinical Trials. PLoS ONE 2013 doi:10.1371/journal.pone.0068409
    (or search for 'trialome' on wikipedia or web)

  • @aishwarya_ganapathy
    @aishwarya_ganapathy 5 років тому

    his voice and the way of speaking ♡....
    and he made wonderful points.
    this is why I want to do medical writing.

  • @ZackaryMusgrove
    @ZackaryMusgrove 11 років тому +1

    This was quite interesting, explains a few things I've seen as well.

  • @Wils0n951
    @Wils0n951 11 років тому +23

    "Everybody Lies" Dr. Gregory House

    • @holdenrobbins852
      @holdenrobbins852 3 роки тому +1

      Especially the pharma companies/researchers.

  • @PacoRV
    @PacoRV 2 роки тому +10

    August 2021 and we are pushing non FDA approved vaccines to the entire population.

  • @Gasp7000
    @Gasp7000 4 роки тому

    Excellent!

  • @afivahdewianggraeni821
    @afivahdewianggraeni821 4 роки тому +1

    I'm just an undergraduate student who amaze to what he talk about, and this absolutely true,
    In the place i'm study at, you can't even pass your final essay if your research result negative

  • @ligable
    @ligable 11 років тому +5

    It takes far more courage to be able to change one's view than stay the same regardless of damning evidence against it. Good on him for bringing it to our attention.

  • @JunoSolarWinds
    @JunoSolarWinds 2 роки тому +3

    Wouldn't it be amazing if the pharmaceutical industry could enslave the whole planet sometime in the near future

  • @reesebrits9381
    @reesebrits9381 4 роки тому +1

    Why do we live in a world where so many people have become greedy and have their own interests at heart; instead of caring for the effects this has on communities worldwide? Pharmaceutical companies should be wanting to help people and make a difference in people's lives, not exploiting them. I chose to study Medicine as I truly care for and want to help others live a better life.

  • @monavocat
    @monavocat 6 років тому

    Thanks

  • @ricardoafonso7884
    @ricardoafonso7884 6 років тому +8

    Ben pointed out what some may say the obvious. Its all down to incentives. If we live in a capitalist system where profit is the ultimate goal, how can anyone expect a different outcome (in medicine or any other field)? Let's be honest and admit we'd all do the same if we were chairing the FDA, SEC, CDC, FED or any other supervising institution. Not saying communism or socialism is the answer .. but this is the other side of capitalism we have to live with

    • @mo-om
      @mo-om 5 років тому +2

      I think things like health and education, among others, should be left to governments. They are just too important to be left to greedy corporates who prioritize profit over the general good.

    • @yingyang1008
      @yingyang1008 5 років тому

      Nonsense - I wouldn't vaccinate a child with something dangerous like Gardasil no matter who much money they threw at me

    • @mattbalfe2983
      @mattbalfe2983 3 роки тому +2

      A vita role of government should be to correct bad incentive structures. Unfortunately, politics usually makes that seemingly impossible to do consistently well.

  • @nightterror4214
    @nightterror4214 3 роки тому +3

    any updates to this issue?

  • @mydearheidi
    @mydearheidi 11 років тому

    awesome!

  • @mathewtroup7934
    @mathewtroup7934 2 роки тому +2

    Relevant today

  • @ketofitforlife2917
    @ketofitforlife2917 3 роки тому +3

    Oh, hm... similar sentiments on current events as well. Fear can make people nearly do anything. That's what government and big pharma work in.

  • @shuttereff3ct593
    @shuttereff3ct593 6 років тому +7

    WTH? people are dying because of these evil companies !

    • @jimmydane34
      @jimmydane34 6 років тому

      Shutter Eff3ct
      Its.ok..the CEO got a 20 million $ yearly bonus for successful profits for year to.uear growth.
      I'm sure they can manage.

    • @BroccoliBeefed
      @BroccoliBeefed 5 років тому

      And if they don't come up with "magic" pills, people like you complain and organize whiny public marches

    • @jazzlynnicole1906
      @jazzlynnicole1906 2 роки тому

      there's no money in healthy people. sick people keep coming back. that's why we need to stop putting our wellness in the hands of THEM, and heal ourselves✨

  • @mattdre201
    @mattdre201 2 роки тому +1

    I wonder if the problem has been fixed. 8 years later.

  • @shoutenry
    @shoutenry 11 років тому

    That is absolutely horrifying.

  • @smalltownboi86
    @smalltownboi86 2 роки тому +5

    Hello covid vaccines... lol

  • @Roedygr
    @Roedygr 6 років тому +4

    Governments should do the testing. Drug companies should pay for it. They might farm out the work. If a testing company is caught cheating it gets a fine and no more contracts. putting it out of business.

  • @kimberlybransford3590
    @kimberlybransford3590 2 роки тому +1

    Wow! How timely is this video?

  • @user-cc5od3zk4p
    @user-cc5od3zk4p 8 місяців тому +1

    I have chronic insomnia. The doctor prescribed an anti psychotic for sleep. I researched the drug and it could be prescribed, off label to patients with a history of serious psychiatric issues. I took it to a pharmacist friend who, was very alarmed. He asked for the script, called the doctor, and, proceeded to blast her. He said she could have caused serious to me and commended me for researching first and, informing him. I’m done with doctors unless absolutely necessary.

  • @cassieoz1702
    @cassieoz1702 5 років тому +3

    The academic journals get a large part of their money from either pharmaceutical research or selling article reprints (to drug reps).

    • @malakeet
      @malakeet 5 років тому

      May I ask how you know this? I'm not disputing it, just really interested in finding proof of it.

    • @cassieoz1702
      @cassieoz1702 5 років тому +1

      @@malakeet it was in an article written by a previous editor of BMJ, cant remember when i read it. Apparently something like (dont quote me) 1/3 of their income was drug companies buying reprints of (favourable) articles for distribution to doctors and was cited as contributing to why they are reluctant to publish unfavourable papers (ie no orders for copies of those)

  • @ShindyK2
    @ShindyK2 11 років тому +6

    Worth favoriting since I'm a PharmD student :D

  • @DaliaDawn
    @DaliaDawn 11 років тому +1

    I massively applaud!

  • @terryrobinson7891
    @terryrobinson7891 4 роки тому

    Bravo!

  • @latanezimbardo7129
    @latanezimbardo7129 5 років тому +10

    when ted used to be good

  • @trishayamada807
    @trishayamada807 6 років тому +7

    These biases in medicines is even worse if you happen to be female. Most human test trials are done on males because female bodies are more complicated with their hormones and the risks of pregnancy.

    • @marielubin8830
      @marielubin8830 5 років тому

      you know because women don't volunteer to get tested,

    • @ishrendon6435
      @ishrendon6435 2 роки тому

      Its unfortunate but male and female bodies are more similar than different not to say theres no difference at all but it isnt as big of a deal. Id argue men because many drugs dont work on male bodies to be exact amd males have higher illness and death rates its logicsl to want to test on males and see how effective drugs are not saying women dont matter but its about the overall picture of treatment. Males have a more delicate biology that requires more treatment overall and thus are better for knowing whether a drug works or not

    • @trishayamada807
      @trishayamada807 2 роки тому

      @@ishrendon6435 LoL

    • @trishayamada807
      @trishayamada807 2 роки тому

      @@marielubin8830 not at all true.

    • @ishrendon6435
      @ishrendon6435 2 роки тому

      @@trishayamada807 that is true ....

  • @RandyBrush1
    @RandyBrush1 11 років тому

    Great vid, thank you for posting...LLP :o)

  • @reddirtwalker8041
    @reddirtwalker8041 2 роки тому +1

    Everyone needs to watch this today.

  • @cartoonhead9222
    @cartoonhead9222 2 роки тому +7

    Jesus, this guy would be executed if he gave this talk today.

  • @AbdulazizUgas
    @AbdulazizUgas 4 роки тому +4

    I'm miserable because i'm forced to take "antipsychotic injections" called abilify. Ive gained 60lbs in two months. I now have anxiety, depression and sm always sleepy and tired.
    Im not accountable to my actions because this isnt the actual me, im being stifled and suffocated

    • @GreenLakes1
      @GreenLakes1 4 роки тому

      Try water fasting!

    • @AbdulazizUgas
      @AbdulazizUgas 4 роки тому +2

      Enibokun Ero I’ve just got off the meds a month ago. Officially a free man :)

  • @tinolino58
    @tinolino58 11 років тому

    very interesting

  • @dreaminginnoother
    @dreaminginnoother 11 років тому +1

    you know, I'm no doctor, but I have dealt with many of them, and I have observed this to be a huge problem. Hopefully on this platform, we can get it fixed and his suggestion to fix is practical and doable in this information age.

  • @safardebon9720
    @safardebon9720 7 років тому +5

    Goldacre makes very valid points - which are to do with the consequences of conflicts of interests, and the negative consequences for patients. However, there is a much more serious problem at the moment. The bulk of the medical profession (along with the public) still believes that you can treat chronic diseases by changing the bio chemisrty of the body. I think drugs & surgery have an amazing influence on positive outcomes in many accute situations, but not in chronic illnesses that are a result of poor nutrition and lifestyle - the bulk of sickness today is due to this. Eating a varied whole plant based diet, low fat, low salt - along with strength/cardio/flexibility training and meditation along with a healthy social life will eliminate much of the chronic disease that we have today. Trying to fix these diseases by changing the bio chemistry using drugs is quackery at its worst.

    • @schlondpoofa
      @schlondpoofa 5 років тому +2

      yeah man let's start managing diseases like diabetes and lupus solely with meditation and cardio!!! that won't kill people at all

    • @mo-om
      @mo-om 5 років тому

      @@schlondpoofa I suppose your chemicals cure diabetes then

    • @amoriicovers
      @amoriicovers 5 років тому +1

      @@mo-om they can't cure type 1 diabetes but they can help manage the chronic condition. They can aid in the weight loss and reversal of insulin sensitivity that can cure type 2 diabetes if caught early enough.

    • @amoriicovers
      @amoriicovers 5 років тому

      @@mo-om without these "chemicals" (read: naturally derived and then refined substances that act on pre-existing structures within the body in the same way as endogenous structures) many people would die or have their quality of life drastically reduced. Many people DO die because of lack of access to medical care. Please learn about how medicines work before coming for them lmao

    • @mo-om
      @mo-om 5 років тому +1

      ​@@amoriicovers I am all for what works be it herb or "chemicals". There is no point mocking people (as was done by the previous commenter) because they prefer certain types of medications. People have lived for thousands of years and used those treatments that have now been relegated to "alternative forms of medication". There is a wealth of knowledge on this type of medication and people are probably better off looking into these again rather relying on profit-hungry corporates who lie, cheat and conceal in order to get a drug to market without worrying about how people are affected.
      I know this would be termed as "anecdotal" but I haven't been to hospital or taken any drug for the last five years. All I had to do was be more conscious of what went into my body and tried to stay fit. The few times I got a little sick, I just used some local herbs and I got well.
      What I have seen people do is just bash alternative medicine and call people names. That is totally unnecessary. So much for your "evidence based medicine". We can see right through the bad science now. I have no problem taking any medicine as long as it would work. Am just not sure I can trust corporates with my health or the health of my family. Not after watching this anyway.

  • @Xaviergonzalez85
    @Xaviergonzalez85 2 роки тому +4

    Someone plz show this to Bill Gates!!!

  • @Wolfwolveswolf
    @Wolfwolveswolf 11 років тому +1

    It is good to see wisdom, where abounding knowledge is at work.

  • @how.disability.justice
    @how.disability.justice Рік тому

    11:02 do you have a link to the article in PLOS Medicine? I'm looking for it within Sept 2012 (within "...this week's edition..." from talk date, which TED says is Sept 27, 2012)