Cystic Fibrosis | Molecular Mechanism & Genetics

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  • Опубліковано 16 січ 2018
  • Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.
    CF is inherited in an autosomal recessive manner.It is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein.
    Source : Wikipedia

КОМЕНТАРІ • 101

  • @willastralian7141
    @willastralian7141 3 роки тому +43

    Indians (I'm assuming sorry) on youtube never cease to amaze me...extremely well explained, better than any university teacher I've had, keep it up

    • @hussainbiology
      @hussainbiology  3 роки тому +9

      Thanks buddy for appreciation...Glad to know that ( Ur assumption is right )

  • @roseb7399
    @roseb7399 5 років тому +11

    The best and most concise description- excellent, thank you.

    • @hussainbiology
      @hussainbiology  5 років тому

      Thanks Rose for appreciation.....Glad to know that it helps...

  • @rokeyaduarte8011
    @rokeyaduarte8011 2 роки тому +3

    wonderful video! very well explained, and answered my exact question down to the "T"! thank you for your help!

  • @veronicaveeroni
    @veronicaveeroni 2 роки тому +2

    I have Cystic Fibrosis! Thank you so much for talking about this

  • @JD-ol7sh
    @JD-ol7sh 2 роки тому

    fantastic explanation! Thank you!

  • @user-ft2lr7pj2k
    @user-ft2lr7pj2k 2 місяці тому +1

    I have my A Level bio exam tmrw and this really helped me understand this since i kept getting every question about cystic fibrosis wrong

    • @hussainbiology
      @hussainbiology  2 місяці тому

      thanks for appreciation..Glad it helps

  • @Sveccha93
    @Sveccha93 5 років тому +2

    Beautiful video. Thank you!

    • @hussainbiology
      @hussainbiology  5 років тому +1

      thanks dear for appreciation....Glad to know that it helps

  • @DREAMMED
    @DREAMMED Рік тому +1

    ❤jazakallahu khairan

  • @ImranMalik78
    @ImranMalik78 6 років тому +4

    shabir Bai U r Doing Great Job keep Doing God Bless BudY

    • @hussainbiology
      @hussainbiology  6 років тому +1

      Thanks bro.......I really appreciate ur words....

  • @user-bd4hk3cp7b
    @user-bd4hk3cp7b 4 роки тому +2

    Thank you 🙏

  • @floydcaoagdan6796
    @floydcaoagdan6796 4 роки тому +1

    Thank you!

  • @preetipawar1732
    @preetipawar1732 Рік тому

    Thank you so much for helping us 🙏❤🎉

  • @shanegrele
    @shanegrele 10 місяців тому

    THANK YOU

  • @nawrcool
    @nawrcool 5 років тому +6

    Thanks a lot for your videos! Really helpful ☺️💛

    • @hussainbiology
      @hussainbiology  5 років тому +1

      Thanks for appreciation..... Really glad to know that it helps......

  • @lrissunflower
    @lrissunflower 4 роки тому +3

    Nice writing, nice voice, nice pace, and easy to follow lesson. Very good; thanks.

    • @hussainbiology
      @hussainbiology  4 роки тому +1

      thanks for appreciation.. Glad to know that it helps ✌️

  • @nooriman7964
    @nooriman7964 Рік тому

    amazing video! thanks so much

  • @cengiz2645
    @cengiz2645 4 роки тому

    thank you so much!

  • @gaedas3447
    @gaedas3447 2 роки тому

    thank you!!! Nice and concise.

  • @akshaykumar-hd1mx
    @akshaykumar-hd1mx 3 роки тому +1

    Very awesome video .....highly appreciated for your hard work....
    keep making such ...again.

  • @tariqhassan7306
    @tariqhassan7306 3 роки тому

    Excellent..

  • @tinaishemachida9798
    @tinaishemachida9798 11 місяців тому +1

    Well explained

  • @Lily108y
    @Lily108y 3 роки тому +1

    Thankyou so much this was the best explanation I found in this topic

  • @Youdonknowme12
    @Youdonknowme12 2 роки тому

    Amazing

  • @makenziel4534
    @makenziel4534 Рік тому +1

    Thank you for this video. It will definitely help me with my bio presentation!

  • @guilmesq6
    @guilmesq6 4 роки тому +7

    Amazing video! Your hard work is helpful and very appreciated. Thank you.

    • @hussainbiology
      @hussainbiology  4 роки тому

      Thanks for appreciation...Glad to know that it helps.

  • @Zetsuke4
    @Zetsuke4 4 роки тому +1

    perfect i want more details

  • @edwardwilson8595
    @edwardwilson8595 5 років тому +1

    Awesome video, really helps out

    • @hussainbiology
      @hussainbiology  5 років тому

      thanks Edward for appreciation...Glad to know that it helps

  • @bleekwater6176
    @bleekwater6176 3 роки тому +2

    Big thanks from Belgium I'm student from Ghent University, very well explained!

    • @hussainbiology
      @hussainbiology  3 роки тому

      thanks for appreciation...glad it helps ✌️

  • @adrishalijutt1263
    @adrishalijutt1263 Рік тому

    Zabardast

  • @abuzarnaqvi2053
    @abuzarnaqvi2053 3 роки тому

    Thankyou soo much 👍

  • @shehhantee906
    @shehhantee906 4 роки тому +1

    Its very informative and helpful THANKSS!!

    • @hussainbiology
      @hussainbiology  4 роки тому +1

      thanks for appreciation..Glad to know that it helps ✌️

  • @raghuveernalla2800
    @raghuveernalla2800 Рік тому +1

    Excellent

    • @hussainbiology
      @hussainbiology  Рік тому

      thanks for appreciation...Glad it helps ✌️

  • @kademarshall4201
    @kademarshall4201 5 років тому +5

    great video just want to say that you left out that sodium ions follow the chloride and form sodium chloride (salt) within the mucus lowering the water potential drawing water in and thinning it
    but again great video

    • @hussainbiology
      @hussainbiology  5 років тому +2

      thanks Kade for appreciation... I might have skipped that part ...Thanks for taking it into notice.... Keep sharing and supporting

  • @user-zs4cf7qz4o
    @user-zs4cf7qz4o 6 місяців тому +1

    very helpful video thank you

  • @kaushik6122
    @kaushik6122 Рік тому

    Good work

  • @sakeenabajwa2473
    @sakeenabajwa2473 3 роки тому +1

    thank you for this useful video I got help in my assignment :)

    • @hussainbiology
      @hussainbiology  3 роки тому

      thanks Sakeena for appreciation.. Glad to know that it helps ✌️

  • @CFlifestyleFoundation
    @CFlifestyleFoundation Рік тому +4

    Thank you for making this video, and for helping spread awareness of this rare disease and the people who are affected by it.

    • @hussainbiology
      @hussainbiology  Рік тому

      thanks for appreciation..Glad it helps....✌️

  • @kayla-kr5dx
    @kayla-kr5dx 3 роки тому +1

    Very helpful! Thank you! :)

  • @reindeerchai1286
    @reindeerchai1286 5 місяців тому +1

    I love you thank you so much for this amazing explanation❤️❤️

    • @hussainbiology
      @hussainbiology  5 місяців тому +1

      thanks for appreciation..Glad it helps ✌️

  • @cosmosheep4306
    @cosmosheep4306 4 роки тому +2

    Can you make a video about gene therapy and the other treatments of cystic fibrosis.

  • @gabriellataylor637
    @gabriellataylor637 Рік тому +1

    he explains it better than my bio professor

  • @dr.subhasisroy4746
    @dr.subhasisroy4746 Рік тому +1

    Excellent vedio. I learned a lot.

  • @RohitRaj-kj1me
    @RohitRaj-kj1me 3 роки тому +1

    Much Appreciated

  • @alaratravels1318
    @alaratravels1318 3 роки тому

    helped a lot for my genetics research paper, got the basics down, now time to design some gene therapy :) haha...wish me luck lol.

    • @hussainbiology
      @hussainbiology  3 роки тому

      thanks Alara for appreciation.... Glad to know that it helps ✌️
      All the best ahead and best of luck 👍

  • @anjalikashyap7142
    @anjalikashyap7142 2 роки тому

    Thanks 👍 sir

  • @learneverythingowaisbhat2348
    @learneverythingowaisbhat2348 6 років тому +1

    Cool

  • @annasitu6643
    @annasitu6643 4 роки тому +2

    Normally, is water draw from inside the cell (intracellularly/ICF) or from the extracellular fluid? Because if water is being drawn from the ICF wouldn't that cause the intestinal cell to shrink?

    • @MariosPOS
      @MariosPOS 2 роки тому

      i would assume it depends on the concentration of different ions etc on the interior and exterior of the membrane at the given time.. since that's the point of osmosis

  • @AH-Sir
    @AH-Sir 3 роки тому +1

    Sooper Dooper

  • @bhagyavijay8856
    @bhagyavijay8856 4 роки тому +1

    Can you please make a vedio on thalassaemia disease

  • @Arif05150
    @Arif05150 3 роки тому

    Sir how water moves out of the cell by osmosis. Lipid layer is hydrophobic

  • @MQMQ-go8nf
    @MQMQ-go8nf 2 роки тому +1

    ❤❤❤😘😘😘😘😘😘

  • @sunidhim.ghatikar3625
    @sunidhim.ghatikar3625 5 років тому +2

    I was searching for your explanation over this concept sir..
    Got it!!
    And we can also think of the anamoly in case of pancreatic endocrine secretion getting thickened due to the effect right sir..

    • @hussainbiology
      @hussainbiology  5 років тому +1

      First of all thanks for appreciation....
      The pancreatic secretions become thick when CFTR gene has any kind of mutation.
      Most of the exocrine functions are halted but there are disruptions in endocrine functions too in pancreas.

  • @iqrasheikh7648
    @iqrasheikh7648 5 років тому +1

    Great video👍🏻

    • @hussainbiology
      @hussainbiology  5 років тому +1

      thanks Iqra for appreciation... Glad to know that it helps

  • @gedenirfiorese3523
    @gedenirfiorese3523 2 роки тому +1

    Pantastic exflanation

  • @yjyoti757
    @yjyoti757 4 роки тому +1

    Sir ap bhut acha explain krte ho...but thodi speed km kro...plz

    • @hussainbiology
      @hussainbiology  4 роки тому

      thanks for appreciation..Glad to know that it helps
      and surely i will lower the speed

  • @rammohanrao603
    @rammohanrao603 4 місяці тому

    My son Kalyan also suffered from cystic fibrosis by chaild hood and after that at the age of 27 years old Lungs transplantation operation at yashoda hospital secunderabad in 06/02/2024 operation success but complications of cardiac arrest in yashoda hospital secunderabad 26/02/2024 first 21 days is very critical my son Kalyan is no more may he rest in peace and Love ❤️🙏 my brain no brain my only son Kalyan operation fail ayyindhi

  • @AWayOfLiving84
    @AWayOfLiving84 6 місяців тому

    Struggling to breathe a lot.

  • @manishkhanna3828
    @manishkhanna3828 6 років тому +1

    😍😘😙

  • @RandomAfrican-qh6vk
    @RandomAfrican-qh6vk 17 днів тому

    oh no please no