He described my exact situation where my dad is a carrier but my mom isn’t, so I need to get tested to see if I’m a carrier before I have kids with anyone
Its a gene which effects movement of salt and water in the body, which causes mucus to be thicker. This can block alveoil as an example and cause infections as a result.
OtterFan48 Mhmm!! Above is correct! It causes many different things in a patient; people with CF are susceptible to coughs and colds turning ‘nasty’ quickly, and have to take lots of tablets to maintain our bodies at a good, regulated level. It’s so very complicated and i’d happily write a whole essay on it but i’m sure you won’t want to be bored with the details.
Both of the above are correct answers but if u want smth simple it basically results in the body product if thick sticky mucus in the air passages and in the pancreas
Two lower case c means that the person is neither a carrier nor has the condition (as cystic fibrosis is recessive). A carrier has one copy of the CF allele (ie c) and one copy of the non-CF allele (ie C).
If you have one lower case c you are a carrier. If you have 2 lower case c you have cystic fibrosis. If you have 2 capital C you are completely unaffected. (he meant two capital C in the comment above)
Do you lose marks if you plot both of the homozygous alleles if asked fora genetic cross diagram (so at 3:00 instead of two boxes you would have 4)? I’ve always been taught to plot both
2:20 How do you know that half of his gametes have the normal allele and half of his gametes have the cystic fibrosis allele? Why can’t it be 1:3 or something like that as gametes are made through meiosis
Each gamete receives one of each chromosome pair so half will receive the chromosome with the CF allele and half will receive the chromosome with the non-CF allele.
Cystic Fibrosis is caused by a recessive allele not a dominant allele, So the person will need two copies of the recessive alleles to inherit cystic fibrosis (cc).
You'll get the marks if you just explain what it is correctly and understandable by the marker you don't really need to make it as complicated or long . He's saying to keep the definitions as short as possible and correct.
To be completely unaffected, you need to be homozygous dominant, hence the CC. To be a carrier, you'd need to be heterozygous (I'll get back to the idea). To be a sufferer, you'd be homozygous recessive. Because both parents are carriers - that means heterozygous - the square is arranged in a way where you'd get 1 part dominant, 2 parts heterozygous and 1 part recessive. That's 4 parts, and 1 part is 25% as a result.
This guy is an absolute champion.
It's true
No I am
got a bio test tomorrow only just found out about it missed this topic and had no clue what it was not i am fully aware thank you Shaun you legend
I hope both sides of your pillows are always cold babe ❤️
??
😘
Wtf 😂
Cheers babe
When I make it in life , You are one of the people I will give credit to for my success
i really struggled with this in lockdown , you explained it in 5 minutes. This man is generally gonna make me pass science
genuinely*
you're actually out here saving lives
Protect this guy as much as possible.
2024 anyone?
yeah
Me! lol
Me
Yep
He described my exact situation where my dad is a carrier but my mom isn’t, so I need to get tested to see if I’m a carrier before I have kids with anyone
Poor lad.. what were the results? Hope you’re okay nevertheless
But you’d need to see if future kid partner is carrier or has it
2023 gang where you at ?
Have my exam today😭
This man is a warrior
Great video, I have a questions, when will the full playlist for Biology Paper 2 be released?
@Fendi -ω- it's done...
His GCSE has probably finished Nate
@@ilyanh7269 nah bro he got there in time dw 💀
What do you think of cheeky AQA putting this paper 2 topic in paper 1?
Cameron Myers I didn’t know how to answer the question because I knew nothing on cystic fibrosis. How can they do that???
Not cheeky at all really, it didn't require any knowledge from this video, rather relating to gas exchange and the digestive system
yh they're just trying to use previous topics with practical examples, but this can lead to confusion which is quite annoying tho.
they just used this as an example. You needed knowledge of digestive system and amino acids to answer it. it was 5 marks
i Did it as a mock and got full marks before doing this topic. you just had to apply your knowledge with the information given.
Great video! Please make more videos about Biology.
Just in time a week before my test!
how about 12 hours
I'm watching less than 2 hours before my mocks 😭
Free Science Lessons Man is a proper chad well done
This helped alot thanks I was absent so I couldn't do the lesson with my teacher
For the Punnet Square at the end, what would be the ratio of people affected to unaffected? 3:1? 1:3?
1:3. For unaffected to carriers to affected it will be-> 1:2:1
amazing explanation and thank you for your time sir
Do we not need to know the symptoms of cystic fibrosis?
no. I think only that it's a disorder of cell membranes
Faith Forever Look at the spec for your paper it will tell you what you need to know.
What does Cystic Fibrosis actually do??
Its a gene which effects movement of salt and water in the body, which causes mucus to be thicker. This can block alveoil as an example and cause infections as a result.
OtterFan48 Mhmm!! Above is correct! It causes many different things in a patient; people with CF are susceptible to coughs and colds turning ‘nasty’ quickly, and have to take lots of tablets to maintain our bodies at a good, regulated level. It’s so very complicated and i’d happily write a whole essay on it but i’m sure you won’t want to be bored with the details.
Both of the above are correct answers but if u want smth simple it basically results in the body product if thick sticky mucus in the air passages and in the pancreas
doing my gcse bio assessment in the house rn 😳
Love this lad appreciate it
I mostly understand this, but when you were doing the punnet squares for both parents being carriers, why did you use Cc instead of 2 lower case c's?
Two lower case c means that the person is neither a carrier nor has the condition (as cystic fibrosis is recessive). A carrier has one copy of the CF allele (ie c) and one copy of the non-CF allele (ie C).
@@Freesciencelessons but if it is two lower case c then the person has cystic fibrosis because it is recessive
If you have one lower case c you are a carrier.
If you have 2 lower case c you have cystic fibrosis.
If you have 2 capital C you are completely unaffected.
(he meant two capital C in the comment above)
Do you lose marks if you plot both of the homozygous alleles if asked fora genetic cross diagram (so at 3:00 instead of two boxes you would have 4)? I’ve always been taught to plot both
No i was taught to put 4 boxes aswell , you still get the same answer it just wors better for you
2:20 How do you know that half of his gametes have the normal allele and half of his gametes have the cystic fibrosis allele? Why can’t it be 1:3 or something like that as gametes are made through meiosis
Each gamete receives one of each chromosome pair so half will receive the chromosome with the CF allele and half will receive the chromosome with the non-CF allele.
Why does CC mean that the person doesnt have cystic fibrosis. Shouldnt they have it because there is a dominant allele
Cystic Fibrosis is caused by a recessive allele not a dominant allele, So the person will need two copies of the recessive alleles to inherit cystic fibrosis (cc).
Lyrical Goddess Thanks for helping out.
Hi Mr Donnelly,
Do we need to know about cystic fibrosis as a disorder?
You do ,
Hi Shaun I have a question. Will I still get the marks in the higher papers if I write the simple definitions just like you say in your videos
You'll get the marks if you just explain what it is correctly and understandable by the marker you don't really need to make it as complicated or long .
He's saying to keep the definitions as short as possible and correct.
nice lesson man thx 😄
3:43 why is it 25% and not 50%?
To be completely unaffected, you need to be homozygous dominant, hence the CC.
To be a carrier, you'd need to be heterozygous (I'll get back to the idea).
To be a sufferer, you'd be homozygous recessive.
Because both parents are carriers - that means heterozygous - the square is arranged in a way where you'd get 1 part dominant, 2 parts heterozygous and 1 part recessive. That's 4 parts, and 1 part is 25% as a result.
what a champ
but if you have cystic fibrosis do you count as a carrier?
no
Carriers never actually have the condition
Will we be told which allele is dominant/recessive in an exam question?
Yes
You'll be told about the parents but I dont think they will tell you which type its caused by
where is the workbook for biology. He keeps mentioning it but it's not even there.
If you've turned off annotations you don't get the card. You'll find them on freesciencelessons.co.uk
aren't we supposed to also know what is actually does to your body and how its treated?
No, everything that is required is included in the videos.
@@Freesciencelessons okay thanks a lot
Ya cant treat it
Sonia Siddiqi
@@sukhjinderdeol7701 you can treat it you just can't currently cure it
I'm revising a month before my ppe exams 😅
Yo here from a science lesson, anyone else?
Anyone here in 2023??
Mocks are gonna be the end of me
aint the cystic fibrosis alleles F and f ?
You can use
any letter
177000th view!