TWiV 971: Another year is viral

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  • Опубліковано 14 гру 2024

КОМЕНТАРІ • 95

  • @lesfaby8997
    @lesfaby8997 Рік тому +6

    UA-cam Timestamps by Les
    07:50 guests were virology stars this year
    immunologists, public health, vaccinologists, ID docs, microbe artists and science writers
    a few others
    12:01 Big 2022 virology events:
    14:13 Current Chinese SARS2 epidemic
    19:09 In memoriam (see ASV for complete list)
    asv.org/about-asv/ bottom of page
    Our favorite 2022 virology stories:
    21:05 Vincent: Paul Offit on bivalent boosters (TWiV 917, 942, Special), Vaccine policy
    27:36 Rich: correlates of protection
    28:31 Dixon: Paul Offit and
    30:32 Dixon: Andy Slavitt
    32:00 Jeffery Taubenberger applied to replace Dr Fauci
    32:26 Rich: TWiV 948: Breathless with David Quammen
    33:21 Katherine Wu (The Atlantic) would be good guest and other writers
    34:42 Kathy: TWiV 915: Mouse mouth to mouse mom 1:00:10
    34:47 Kathy: TWiV 958: Pass the RNA and have some venison pi
    39:29 Brianne: Spillovers (TWiV 923 and 876)
    42:37 Vincent: Giant viruses (TWiV 873, 906, 968)
    49:07 Dixon: TWiV 960 - Getting Funky with Dan Wilson
    57:37 Rich: TWiV 927: Merchlinsky vs monkeypox
    1:00:03 Automat automatmovie.com/
    1:00:5 Trudy Rey blogs at www.virology.ws/author/rey/
    www.virology.ws/2022/08/04/transmission-of-enteric-viruses-through-saliva/
    1:01:09 Kathy: What happens when 2 different viruses infect a cell
    1:07:27 Brianne: TWiV 869: Epstein-Barr virus and MS, a perfect storm
    1:10:03 IL1, IL1a paper
    1:10:54 Favorite episode titles
    Thanks to:
    1:14:30 Website audio timestamps by Jolene. Thanks!
    1:14:57 Twiverse
    1:15:23 Show notes for Daniel's TWiV Hannah Berhay (please correct if I spelled incorrectly)
    1:15:48 Video Editor: David Ramada for Daniel's TWiV
    1:16:00 New Audio Editor: Peter Duff
    1:16:52 Cara Pound publicist
    1:17:35 incubator almost completed
    Thank you to all contributers
    1:21:48 Letters read on TWiV 968
    1:37:29 Weekly Picks
    Dickson - Jazz Project: Tenor saxophone: John Coltrane/Dexter Gordon/Stan Getz: John Coltrane: Signature album: Giant Steps: Signature song: Blue Train; Dexter Gordon: Signature album: The Other Side Of Round Midnight. Signature song: Round Midnight; Stan Getz (with Charlie Byrd on guitar): Signature Album: Jazz Samba; Signature song: Desafinado
    1:41:54 Brianne - A Full Circle Rainbow over Norway
    1:43:30 Kathy - Frozen soap bubbles
    1:44:13 Rich - It’s Turtles All the Way Down in the Fossil Record by Asher Elbein
    1:46:04 Vincent - Vincent’s Top Ten Music
    ua-cam.com/play/PLGhmZX2NKiNmEsrutaQJulBIM2Q84tkp2.html
    1:50:21 Listener Pick
    Charles - Wayne Bergeron and Vince DiMartino MacArthur Park

  • @marklemont3735
    @marklemont3735 Рік тому +13

    I am so grateful for this TWiV group of active and retired scientists, taking the time to be pleasant, civil, and at times humorous with one another. You all do this while discussing the wonders of science and discussing research. And then there is the wonderful enlightenment section of your favorite picks which also broadens my knowledge of the world. It is so wonderful to hear Dickson’s point of view from his years of wisdom and and at the other end of the timeline the bright light and enthusiasm of Brianna who is thinking about current and future research. I found you in early 2022 and and plan to continue to enjoy you all. Stay well and healthy in this new year.

  • @cynthialeech2507
    @cynthialeech2507 Рік тому +14

    Best wishes for a healthy and prosperous 2023. Thank you TWIV for your fantastic science content!

  • @priyasingh-po5yr
    @priyasingh-po5yr Рік тому +8

    Wishing everyone at microbe TV a happy , informed & safe new year 🎉

  • @kathleenp3135
    @kathleenp3135 Рік тому +8

    HAPPY NEW YEAR!❤️

  • @derrith1877
    @derrith1877 Рік тому +3

    I have been listening since Ebola in W. Africa in 2014. Most of the time I listen to the audio only podcast, but I discovered you were also on UA-cam this year. Sometimes I listen/watch both version of a given episode. I listen to all the TWIx including Immune ... you feed my generalist interests in biology! Keeps this retired person's mind still alive & kicking!

  • @redhen689
    @redhen689 Рік тому +7

    Happy New Year all. I took a Covid test around the time this video released… tested positive. As a respiratory therapist who has been working around Covid patients, and a participant in the Covid vaccine trials, I have been thinking that this day might be coming. So far I just have a runny nose and sore throat. Hoping that is the extent of it.

    • @denkerdunsmuir3370
      @denkerdunsmuir3370 Рік тому +4

      Praying for an uneventful and swift recovery with no long-tail symptoms! Be well!

  • @peterjf7723
    @peterjf7723 Рік тому +9

    Happy new year from Antalya, Türkiye where it is 12°C, expected to rise to 19°C this afternoon. Unseasonably dry here at present. Air quality is currently "Unhealthy for Sensitive Groups" which includes asthmatics like me. We could do with some rain to clear the dust and improve the air quality.

  • @amyrugala246
    @amyrugala246 Рік тому +7

    I agree with Richard, great interview. I was so impressed, I went out and bought Breathless the same day! Thank you for a great year! ps received my Spike long sleeve t-shirt and just love it. Keep on keeping on Vincent and I will continue to come along for the ride!

  • @susanfleming2123
    @susanfleming2123 Рік тому +4

    I remember the automat. We moved from NYC to Montvale, NJ when I was young, and drove back every month or so to visit grandparents in either Brooklyn or 33rd and third Manhattan, my old apartment bldg where my mother's folks still lived. Sometimes we had to make a stop on Delancy Street to get my father fitted for a new suit. All trips began with a stop at the automat, or Horn and Harnets. What memories.

    • @lismartinez5363
      @lismartinez5363 Рік тому +2

      You might enjoy this.There is a documentary out on the NYC automats. So much fun to watch .

  • @elliecahill5946
    @elliecahill5946 Рік тому +3

    I am so grateful that I found TWiV in...2020, I think. I'll turn 66 this month, & I've learned so much in the past 2 years. (We should never stop learning.) I'm currently reading "Breathless"; I recognize so many of the terms from watching/listening to TWiV. I always pass on what I'm learning to my co-workers, particularly about SARS-COV-2, and they're always grateful. May we all continue to increase our knowledge in 2023, and may more heed it!

  • @kenmfrancis
    @kenmfrancis Рік тому

    Forever grateful and uplifted by this wonderful service … thank you to you all and my bestest wishes for a fantastic year!!!

  • @doreeno3792
    @doreeno3792 Рік тому +3

    Happy New years from patterson, nj where I'm at a sit and wait at hospital...so glad to have my microbe, tv fam. Happy days all!

    • @MicrobeTV
      @MicrobeTV  Рік тому +3

      I was born in Paterson NJ and lived there until I was 8 years old!

    • @doreeno3792
      @doreeno3792 Рік тому +3

      Some day, I hope to drive over to william carlos williams home/office and see his historic artifacts at the Meadowlands museum! Cheers.

  • @karenkaren3189
    @karenkaren3189 Рік тому +2

    Happy New Year from Southern California
    It has been a blessedly rainy week.

  • @kazoz3520
    @kazoz3520 Рік тому +5

    15:40 There's actually more people double vaccinated in China than in the US (China 90%), ie they have a very high vaccination rate. But unfortunately it's the elderly that were more hesitant to get vaccinated (vaccination rate lower from 60 yrs up).

    • @minRef
      @minRef Рік тому +4

      All current vaccines on Earth have limited effect on reducing long covid.

    • @denkerdunsmuir3370
      @denkerdunsmuir3370 Рік тому +1

      Long-tail. ... Who's studying this? What are the current, educated hunches about the causes and possible prevention/ameliorative measures, if any, by the TWIV panel members?

    • @kazoz3520
      @kazoz3520 Рік тому +1

      @@minRef With Vincent's recent comments on the fact that severe acute stage COVID patients are at greater risk of Long COVID (particularly organ morbidity subsets), I don't think it has registered with him the fact that due to the continued high prevalence and infection rates of SARS-CoV-2, and that most symptomatic cases are mild to moderate, not severe, it means that the vast majority of Long COVID cases were after mild to moderate acute stage infections.

    • @kazoz3520
      @kazoz3520 Рік тому

      Note too, there has been an inhaled COVID-19 Omicron targeted vaccine, adenovirus based, available in China since Oct 2022, as a single dose booster. Plus there has been R&D in other vaccines, including mRNA. So it is inaccurate to suggest that China had done nothing to improve on the efficacy of their first generation (inactivated SARS-CoV-2) vaccines.
      Mind you, Chinese vaccine company Fosun Pharma did a deal with BioNTech (but not Pfizer) way back in Mar 2020, a collaboration to trial, manufacture and distribute BioNTech's COVID mRNA vaccine in China, etc. This is how BioNTech's mRNA vaccine became available in Hong Kong. But unfortunately it hasn't been the case to date, not released for (most of) mainland China's citizens.

  • @lismartinez5363
    @lismartinez5363 Рік тому +4

    It is a good morning because there is a TWiV episode for me to listen to. Thank you to the TWiV team. You make my day. Happy New Year. Keep up your picks also- they are so much fun, Lis

  • @mylaughinghog
    @mylaughinghog Рік тому +4

    Happy new year!!!

  • @maryrowe506
    @maryrowe506 Рік тому

    Finally got a chance to watch. Happy New Year to the TWIV crew and thank you for letting us hang out with you and learn.

  • @celosiapigeon
    @celosiapigeon Рік тому +3

    I'm listening in 2022! It's Dec 31 2022 at 11:03pm in Alberta Canada as I type and listen hehe

  • @wednesdayschild3627
    @wednesdayschild3627 Рік тому +2

    15:40 sinovac was only 58 percent effective in the original strain. China has no mrna vaccines at this time. They are under development. The WHO said omicron broke the quarantine and they were out of money.

    • @gribbler1695
      @gribbler1695 Рік тому

      The protesters made a big contribution to it, but state media pushed other factors.

    • @christopherrobinson7541
      @christopherrobinson7541 Рік тому

      The tradition vaccines in China have almost no effectiveness against the Omicron variant. One least one the their mRNA vaccines was under trial in Indonesia, but does not appear to be very effective. Recently China has agreed to purchase mRNA vaccines from the US, but I do not think any have been delivered. They were previously offered in 2021 and Summer 2022. To late to have any impact on the current wave.

  • @tatianabeastmode6573
    @tatianabeastmode6573 Рік тому +3

    So glad the epitope pun is still going strong!

  • @elizabethhoward7186
    @elizabethhoward7186 Рік тому +1

    You should interview Ed Yong -- he did fabulous viral reporting for the Atlantic during COVID

  • @PifflePrattle
    @PifflePrattle Рік тому +3

    We need a collective noun for a group of Richard Condits.
    I suggest conduit.
    A conduit of Condits.

  • @EnvironmentalCoffeehouse
    @EnvironmentalCoffeehouse Рік тому

    Happy New Year to all of you who keep me sane! 🎉

  • @2listening1
    @2listening1 Рік тому +4

    Did anyone pick Tom Monath as a favorite interview? I thought it was legendary. 😊👍🙏

    • @lesfaby8997
      @lesfaby8997 Рік тому

      ua-cam.com/video/RvWZ4wx7cVU/v-deo.html

  • @BigGuy8059
    @BigGuy8059 Рік тому +4

    10 PM New Years Eve in San Diego. 56 F with 16 MPH gusts. No rain now, but it's coming later tonight. 2023 will come right around your picks. The policy in China almost seems like some people in leadership positions did this purposely to eliminate a lot of elderly people who are no longer productive. But of course that is unthinkably non-Confucian.

    • @denkerdunsmuir3370
      @denkerdunsmuir3370 Рік тому +1

      Yipes! I wondered that in 2020 about Trump's and Republicans pandemic response, too. Thankfully, this was not a majority approach that I am aware of yet.

  • @tomsteinberg8106
    @tomsteinberg8106 Рік тому +1

    paraphrasing Dickson ~ 54 min. 50 sec. -- the privilege and pleasure of having the TWiV panel come into our lives.

  • @joannabassi2408
    @joannabassi2408 Рік тому +1

    Happy New Year to all ...!

  • @aswang7890
    @aswang7890 Рік тому +1

    1:01:09 Kathy: What happens when 2 different viruses infect a cell | Thanks for Kathy mentioning the paper on chimeric viruses following co-infection of cells plus microscopy work. Very interesting. This phenomenon is near and dear to my heart because at the start of Covid, there was an ID doc doing a seminar online and I asked if this phenomenon would happen in humans. What if someone is coinfected with HIV and SARS-CoV-2, can you get chimeric virions by mixing proteins from the two viruses. Or Ebola and the coronavirus? The ID doc totally shut me down saying viruses are so different and there is no chance they would mix proteins and genomes like that. But I was dubious. But I couldn't really challenge him since I had no data. Now I do! I will be tracking that ID doc now.

  • @rachcor1333
    @rachcor1333 Рік тому

    Happy New Year to all of you from The Isle of Man. I am so pleased I found TWiV. So that's at least one thing, I can be thankful for the pandemic for!!!

  • @ralfsigmund3491
    @ralfsigmund3491 Рік тому +3

    新年快乐🍾️🎉

    • @lesfaby8997
      @lesfaby8997 Рік тому

      Translation: Happy New Year.

    • @denkerdunsmuir3370
      @denkerdunsmuir3370 Рік тому +1

      Happy New Year! If you are celebrating, Happy New Year of the rabbit!

  • @chayashida
    @chayashida Рік тому

    1:42:50 Kathy remarks about Brianne's pick of the week (the full circle double rainbows and how it has a full diameter is 84 degrees). Could they mean that the diameter is 84 degrees longitude or latitude possibly?

  • @FewFishManyWorms
    @FewFishManyWorms Рік тому

    Of course Rich would give a Calvin and Hobbes shout out! Awesome

  • @PLERF
    @PLERF Рік тому +1

    Tenor sax? Hank Mobley. Michael Brecker. Pharoah Sanders. An album to check out. Mulligan Plays Getz. They swap horns. When you do Bari sax, Serge Chaloff better be there, Buster!.

    • @denkerdunsmuir3370
      @denkerdunsmuir3370 Рік тому +1

      Another sax fanatic! Love, 💕💕💕💕💕 it! I'm more Cannonball Adderley, Kirk Whalen, Stanley Tarrintine, Eddie Harris, fan, but Dexter Gordon, Coltrane I admire and enjoy their sounds, too.

  • @lorayejones4777
    @lorayejones4777 Рік тому

    HappyNew Year🎉🎉🎉🎉

  • @tomsteinberg8106
    @tomsteinberg8106 Рік тому

    Rich Condit ~1:29:57 -- thanks for speaking clearly and plainly about lies spread by Epoch Times. This is no time to mince words.
    Too bad that Brianne's later comments ~1 hr 36 min can't be heard on the recording.
    Re Dickson: "listen to the bass" Just so -- I think of Jack Casady.

  • @johndoe09876
    @johndoe09876 Рік тому

    Audio issue at 1:35:52

  • @HotelPapa100
    @HotelPapa100 Рік тому +3

    Apparently virologists don't need basic arithmethic. ;-)
    Happy New Year all!

  • @richardseymour3399
    @richardseymour3399 Рік тому

    No sound from Brianne around 1:35:00 makes me wonder what y'all were laughing about.

  • @denkerdunsmuir3370
    @denkerdunsmuir3370 Рік тому +2

    Miles Davis, Time After Time, and Mrs. Morisine; Jamie Hendrix, All Along the Watchtower; Oscar Brown, Jr. Album -- Sin & Soul; Neal Young, Heart of Gold; Dire Straights , Sultans of Swing; anything/all Queen, especially Another One Bites the Dust, and Ed Sheeran especially Beautiful People/Bad Habits; all Motown especially The Marvelletes', The Hunter Gets Captured by the Game, and any Smokey Robinson and The Miracles especially What's So Good About Good-bye and I'll Try Something New; and any Doo Wop; and last but not least, Try Me by James Brown, and Big Mama Thornton's original, Ain't Nothin' But a Hound Dog, and Charlie Christian first electric jazz guitarist, Swing to Bop- You Tube, died 1942, and any songs/albums by Hiroshima, & Third Force.
    I could go on and on about my favorite music as my roots and tastes in music were formed by scientists such as yourselves and go from classical to Hip Hop disco/dance hall and any music from & for dance, clubs, parties!
    Happy New Year to you all! And, heartfelt appreciation for your reminder in this era of " alternative facts" that the evidence, what you refer to as the data, drives fact and truth; not a bullying blowviator who has never paid his fair share. (Sorry for slip into politics, but it's the truth, and the documents to prove it are in the public record, and we're entered into the Congressional record.

  • @tonaruch8623
    @tonaruch8623 Рік тому

    Didn’t you have the guest scientist Quazmiki or was that 2021? How do you spell her name anyway?

  • @gottagowork
    @gottagowork Рік тому +2

    "Low vaccination rate" is what I've been hearing constantly too, until I recently looked it up and found China to be at 89% fully vaccinated - that's better than most of us. That's only from ourworldindata though, and let's just say I'm reluctant to blindly trust anything from China (ref flood event a while back). As for "lower vaccine efficacy", what is that based on? Our vaccines *used* to be great, like 90+%, but that was based on earlier variants and we only heard about antibodies. Nowadays with quickly waning antibodies and high evasiveness, that portion of the protection doesn't seem that great anymore. Now it's pretty much only memory based, so what do we know about their vaccines wrt memory protection?

    • @aq9415
      @aq9415 Рік тому +1

      It's the vaccination rate in the elderly which is low. It was 65.8% of over-80s having had two doses as of November 2022, 40.4% having had booster. I think it was data out of Hong Kong that showed 3 doses of Chinese vaccines was equivalent to 2 doses of the mRNA vaccines.

    • @gottagowork
      @gottagowork Рік тому +2

      ​@@aq9415 Ourworldindata currently states 57% on boosters for China as a whole - again assuming they have provided accurate data. Belgium at insane 99% (with no mandates?), followed by Sweden (92%), Finland (77%), Norway (69%), Denmark (62%), Vietnam (58% - lower than I expected) all above China, and US slugging behind at around 40%. Was the ones I had up at the time.
      Where do you find takeup per age group, especially for China?

    • @aq9415
      @aq9415 Рік тому +1

      ​@@gottagowork BBC article: "China Covid: How is it tackling the latest surge in cases?" - I've corrected the numbers in my original comment as I misquoted. The UK has quite a good chart on an ONS page titled "Coronavirus (COVID-19) latest insights: Vaccines".

    • @marklemont3735
      @marklemont3735 Рік тому +1

      The rate of hospitalization has decreased, so far, in the elderly who have been vaccinated and boosted. I like less of a chance of being hospitalized, from a vaccine, and less symptoms or long COVID from an infection.

    • @deborahfreedman333
      @deborahfreedman333 Рік тому

      If you'd been listening to TWiV, you'd know not only are the elderly considered too fragile to be vaccinated, in China, but also that Ag titers are not an accurate correlate of protection. Stop ignoring cellular immunity. The poor efficacy of the Chinese vaccines have been proven by numerous studies, from Argentina, Brazil, and other parts of the world, that compared the protection against severe disease of numerous vaccines. The mRNA vaccines were the best, followed by the chimp adenovirus vectored vaccines, and in last place were the attenuated virus vaccines China employed.

  • @tonaruch8623
    @tonaruch8623 Рік тому +1

    If you were looking for a female author how about science writer Mary Roach? I love her books Gulp and Fuzz

  • @vvanderer
    @vvanderer Рік тому +2

    Is Ladybird Lakenamed after Mrs LBJ? He was the most colorful non criminal in the White House in the post war years, maybe reaching back further. And despite his hokey manner he was a political and humanitarian giant

  • @gbensen8069
    @gbensen8069 Рік тому +3

    Your panel says go with the data, apparently the panels choice is to ignore the research , by people who have the same level of expertise and education that put them at the same level in their fields as the panel, who are gathering data on the harmful side effects of the panels favorite medication.
    These same qualified researchers who are recommending that everyone take a step back and let's do better follow up before we push something with an unknown outcome in the future.
    No I am not an anti vaccine person.
    If you are at a high risk and you make the choice, along with your medical advisor, then take the medication.
    Yes it is a medication, at this point it provides no long term prevention, which seems to be something your panel agrees. ( The long term prevention)

    • @aq9415
      @aq9415 Рік тому +4

      "ignore the research , by people who have the same level of expertise".. such as?

    • @aq9415
      @aq9415 Рік тому +3

      "at this point it provides no long term prevention, which seems to be something your panel agrees".. I get the impression that their general consensus is that vaccine derived immunity will provide long lasting protection against severe disease.

    • @marklemont3735
      @marklemont3735 Рік тому

      So is the Tdap vaccine also a “medication” in your mind because it needs a boost every ten years and can’t just be given once in a lifetime?

    • @gbensen8069
      @gbensen8069 Рік тому +2

      @@marklemont3735 your comparison , in my mind, is a poor one, and estimated 30 days compared to 10 years.
      Tdap as you probably know treat 3 issues and has long been recommended at 10 year intervals.
      I believe that the panel, all agreed the original shot should provide protection from severe disease from the emerging types of covid provided they are of the same origin/ family ( my words not theirs). So repeated boosters are medication, treating the symptoms if you should get the infection.
      All just my opinion.

    • @deborahfreedman333
      @deborahfreedman333 Рік тому +1

      @@gbensen8069 It sounds like yours is an uneducated opinion, and thus worthless. Vaccination is a preventative, not a medicine. I suggest you take some relevant science classes, since you don't understand the field, or who is actually an expert.

  • @aswang7890
    @aswang7890 Рік тому

    Didn't you talk to Shane Crotty in 2022? Maybe that was in 2021? The Covid pandemic is such a blur.