Waw one of my favorite UA-cam creator commenting on another incredible UA-cam creator! Awesome! Also thanks for writing down my exact though on that ^^
Admit it or not, it's much harder to make the song stcik to the topic, make sense, sound good, and have exactly the same rhyme scheme everywhere He's a genius
madgrinchhatter madgrinchhatter I came back after listening to the original, damn it was unbearable. Also, is it me or does Dorothy sound more lively than the original singer ?
Syllables lead to difference in intonation which matter to fitting to a particular melody. It is less problematic for less intonation incline languages like English but it's a problem nonetheless. Vietnamese for example, depend heavily on intonation to differentiate the words, and choose a wrong one lead to catastrophe...
Two of my favorite channels interacting. Always smile when I see videos come from these two. As a biology major I love the videos coming from both channels with a passion. I always learn from watching yall's videos. I decided to write my microbiology research paper on CRISPR because of A Capelle Science! And I used info I learned from Tierzoo in a presentation I had!
Seriously. Please do a collab! I freakin' love both of your channels. I've been showing a bunch of my friends your videos, TierZoo and they love em as well. S+ on the UA-cam tier list, both of you gents. Entertaining AND informative! My very favorite type of content.
Nanobots are just synthetic life and pseudo/protolife. Combined with research being performed into reverse engineering enzymatic pathways we'll eventually find ourselves no longer limited by the small pool of naturally available enzymes, nor the need to program complex nanobots from the ground up, as we can just create the code for synthetic enzymes using RNA/DNA and splice it into yeast to create bioreactors for pretty much any chemical structure under the sun (and given 10 years have the ability to do it from your PC and a desktop printer for the cost of a single dose of insulin [which gets very cheap very quick when you can basically create it in a bottle of ~sugar water])
Joonas Mäkinen i was the same originally, but I heard “Shape of You” a few times this summer (mostly in stores). It was a weird and vaguely disappointing experience. “Molecular Shape of You” is much better.
another solid hit, i'm a biologist with zero robotics background and i feel like i learned something! the side by side diagrams and animations of biomolecules was like a lightbulb moment. time to read all those references while i loop this video for 4 hours.
What where your final thoughts on this? I found it quite interesting, I'm only a novice though. Are the diagrams of biomolecules accurate? I'm trying to further understand the plausibility of this
Organic chemistry... Think you'd be willing to do one in the style of Linkin Park? Please? Linkin Carbon (Orgo Chem) (It starts with) Benzene, demystify It's all about matter, check, verify Carbon that binds, atoms aligned to combine Explain the enzymes (All I know) “C” forms a covalent ring Watch it show up in spectrometry See it count up in the usual way We build life this way (It's so unreal) Chemical math will show Mass is conserved and entropy grows Trying to hold on to electric charge flow For covalent bonds to (Molecule grow!) Balance elements each side, reaction codified It's a work of art With this chemistry we'll eventually make 'em cleverly Molecules that we can use Without no harm In the end It's all about matter Make cortisol Or methanol In the end It's all about matter Amines, the alkane chain Nitrogenous molecules in aryl rings Keep that in mind, atoms that bind To fill valances with (Shared electrons) Despite assays, there's poor purity Refine lab processes to maturity Wash solutions, titrate and heat to precisely Create a molecule Things aren't the way they were before Alchemy's dead, there's no magic in it anymore Not that it worked back then But it all comes back to “C” (Orgo Chem!) Know when you acidify an organic sulfide It smells like a fart With this chemistry we'll eventually make 'em cleverly Molecules that we can use Without no harm In the end It's all about matter Make insulin Or epinephrine In the end It's all about matter Linus Pauling It was you Who figured out the code Chemical bonds Organic chemists need to know See the table Read the code Match them up As you go Fill the shells Organic chemists need to know Molecules that we can use In the end, it's all about matter Like building blocks Our molecules In the end, it's all about matter.
@@GamerFromJump It's says in the title...Don't bother looking it up, it's really not that good. Another example of parodies actually being better than the original.
I would learn a lot more about biology and chemistry if you did, because you need some Grad level information to understand all the references in your songs
Ya, his channel is too underrated . He deserves more than a million subs . But a fake video uploader channel got more subs .(You also know the name(s))
You never fail to surprise me with your clever position of words to mimic the original lyrics while also conveying a coherent scientific message. The harmonies are perfect as always!
Honestly, I don't mind the long wait times between your covers! Every time you put out a new cover, I spend days just listening to it on repeat - then I start researching the topic trying understand all of the lines in the song on a deeper level. This basically gaps the entire wait time - until a you put out a new cover I can start researching! Thank you both for your awesome work! You're amazing!
Is there a place that gives a basic explanation of everything in the song? I found an article about his Whole New Worlds song, but couldn't find anything for this song. (www.syfy.com/syfywire/whole-galaxy-new-worlds-capella-science-exoplanets)
Putting the "conceptual" diagrams next to actual proteins used by microorganisms that demonstrate the concepts illustrated so elegantly allows the viewer to naturally connect the ideas in their head. Genuinely an incredible video.
I LOVE when an acapellascience video pop in my notification when i'm not expecting it, a few second in the video and... it's a masterpiece. More video coming, it's a big YES, you deserve so much more views for these. (sorry for aproximate english, french musical scientist here)
Not only is the song phenomenal, the animations make it actually understandable. What is beyond my understanding is not the topic but the awesomeness of this video! EDIT: Holy molecule, there's even a reference list down in the description!
How does this only have a half-million views? This is legitimately a masterpiece. Somehow you keep raising the bar higher with each song and then proceed to crush it with the next. The animations, lyrics, and actual performance is simply remarkable. The best part is, it doesn't matter what order you listen to the songs; All your stuff from day one is phenomenal and sets the bar super high.
Great Song: Check Original, informative and entertaining lyrics: Check Interesting topic: Check People who sing really, REALLY well: Check Yup. Thats officiall the best video on youtube
I'm so glad you're back! Also, I wanted you to know that I picked up that book Endless Forms Most Beautiful because you recommend it in your Evo-Devo video. What an amazing read! I dont know much about biology so a lot of it went clear over my head, but even the small percentage that I was able to pick up on was incredibly eye opening. Thank you for doing what you do! I learn something new from each one of the songs you put out.
Scientist being given the status and craz like Pop stars is a sign of humanity being going in right path. Cheers to the community of shared future for mankind.
A year and a half ago I tried to explain to people what use could molecular machines be. Now I can add another application to that list -- a very catchy cover of an overplayed song. I love this, thanks, Tim!
Thank you for this!! I’ve shared your videos a few times in the classroom, as often as applicable really. People have gotten better at making science fun but fun fades- you make it catchy and THAT’S the game changer. It allows info to transcend the moment into part of the thought process, part of the dialogue. We need more catchy science!
nah, he rhymed fuuuuuuuuuuuuuuuuueeeeeeeeel with throoooooooooooooooouuuuuuuuuuugh, energetic with let it and he just changed the tone to not have to rhyme setup with anything, otherwise its rhyme partner would have been load.
@@robinlindgren6429 the way I read it the rhyme structure is A B B A B C, with A being fuel and through, B being energetic, setup, and let it and C is load. I would reject the argument that the first 2 B's aren't a rhyming couple as the BC pair are not a rhyming couple. This is because the "let it" line rhymes with the other 2 and you can't treat the last line the same since it breaks the B structure in both length and tone. But that's just my analysis and your is valid too☺
Yup. Very nicely done half-rhyme/internal rhyme chain. By using the right intonation, he created a partial alliteration and "rhyme" in the syllables "ener" and "se" and "get" and "set" then builds on it with "let it", "ener" --> "se" --> "le", and "get" --> "set" --> "let"--> "it" You see stuff like this all the time in good rap, but there they take it even further, they keep it going and even revisit a chain after a few lines etc.
A whole semester of bio science in a single song, simply over the top amazing work. There should be a grammy/science type award for this. And as to add "the right fuel", the way she says: "break me down", infuses the entire song with sensuality, just brilliant.
As a student in Nanotechnology i can say I've actually learned a lot from the animations and explinations in this video, as well as your ed Sheeran chemistry video. Keep up the good work!
I actually am an organic material chemist. I work with another research academic chemist that has worked with the study of nanobots under her post doc. Her work dealt with the area hit at 1.26 minutes into the song.
Strangely the video it's not on your channel in UA-cam. I only knew that you release a song by bandcamp and acess the video from there. Great work as always.
I wasn't sure about this one at first, but after listening all the way several times I'm completely on board. Absolutely one of your best, it's remarkable that you can make these amazing parodies with such a consistently high standard.
To plan a nanobot, you need to carefully map out the molecules that will make up the nanobot. Just like in living organisms, the choice of molecules and their arrangement will determine the nanobot's structure and function. Additionally, you must include motors for movement, similar to how motor proteins like kinesin and dynein operate in cells. These motors will enable controlled motion and navigation at the nanoscale. Establishing communication signals is essential for the nanobot to interact with a central command or other components. This can be achieved by designing specific signals or chemical cues that allow the nanobot to receive instructions and transmit information. The software and logic programming of the nanobot are crucial for its operation. Similar to how DNA encodes genetic information, the nanobot's programming determines its behavior and functionality. By programming specific instructions and logical operations into the nanobot's software, you can control its actions and responses to stimuli. Controlling the movement of the nanobot is crucial because thermal energy constantly causes motion at the nanoscale. By carefully selecting the components and links within the nanobot's structure, you can limit the states it can assume and ensure controlled movement. To make the nanobot effective, it is important to overcome barriers and minimize energy expenditure. By planning its design to navigate obstacles and conserve energy, you can optimize its performance. This can be achieved by incorporating mechanisms similar to ATP synthase, which efficiently convert energy for the nanobot's tasks. In terms of information processing, you can design the nanobot to handle nano-informatics tasks. This involves creating structures for storing and retrieving data, incorporating switches and flip-flops that can be controlled chemically, photochemically, or electrically. By incorporating logic gates and decision-making capabilities, inspired by DNA and RNA polymerase, the nanobot can process information and perform calculations. By considering all these aspects, you can create a nanobot that acts as an information scanner, capable of reading and writing coded data. This gives you the flexibility to program the nanobot for various tasks, making it a versatile and powerful tool. With its ability to perform complex operations, the nanobot can be seen as a synthetic counterpart to biological processes like DNA replication, intracellular transport, and mitosis, albeit on a smaller scale. In summary, planning a nanobot involves careful consideration of its molecular composition, movement mechanisms, communication signals, and software programming. By drawing inspiration from biological systems and incorporating efficient design principles, you can create a functional and efficient nanobot for specific purposes.
Bohemian Gravity introduced me to the channel years ago, but it was finding Bring Me A Gene a couple weeks ago that reminded me I'd never subed... I fixed that. And now this song is stuck in my head. You're welcome for the 1 year + reminder that it's STILL REALLY GOOD.
I knew that nanobots are incredibly small,but I didn't know that they were the level of molecules! If they're making them so they function at the molecular level,then that's even more amazing!
Thank you Acapellascience. It's an outstanding video, one of best. I love the molecular tinker toys. The female vocals were a great addition. Thanks Dorothy Andrusiak!
I really like how you listed your patrons alphabetically by first name. It makes it so easy to find people I know who support you. And who still needs a little nudge. Thanks, Tim.
Great topic, images, music, and all skillfully put together with rich content. Dorothy's singing and delivery is fantastic. Love watching and re-watching this video.
How much time do you spend learning before starting to plan the songs? I would think you need to plan your songs a lot more than one would normally. Are other people part of that process? How about making the videos? Anyways, you are part of the top layer of what Internet has to offer and I'm truly grateful for the work you do.
I kind of see this as capping off a trilogy that began with "The Molecular Shape of You" and continued with "Evo Devo". The first two are what life is made of, and how it got to be as complex as it is. And this would continue it by showing the genesis of artificial life.
I love the parodies here. Normally your own facial expressions jive with the tone of the song, but what made this really fun to watch were the facial expressions of your guest artist. She seemed like thoroughly enjoying the singing, unconcerned that she is being recorded. Priceless expressions. :D
I found this video in my sub box 2 h ago and have watched it a total of 10 times so far, only interrupted by some of your older videos. Amazing work as always, and Dorothy was awesome too!
Greetings from Brazil! For sure it is pretty much better than the original one. You're amazing Tim! Me and my friends from college just love your channel. Thanks for being awesome.
Im on the programming side of things if you want to understand this more I reccommend learning what a turing machine. Any system in which you can create logic gates and wire thier outputs into the inputs of other logic gates you can create a computer. Sebastian Lague had a great series in which he creates and explores the purposes of rudimentary computer componets and it comes together quite nicely how you could create a computer with theese simple tools.
n°2 (Isaac) : «do not worry, we can understand you» n°3 (Timothee) : It is very Reblochon by here tell me > Local expression to say that there is a lot of French in the area ;) (Reblochon is a French cheese)
I don't know what is incredible, the song, the singer, the concept (I mean it is literally randomness + a lot of times to evolve) or the people find out the concept. Probably all of them
I absolutely love the work on molecular machines, it really excites me as a chemist. Especially Fraser Foster's work, as a fellow Scotsman I am really a fan of his work and it's nice to see this area of science explored. Fantastic work as usual!
Lol, I just did a short thermodynamic unit in my first year Uni Biology class. I’m not an expert, I just understand the basic theory. Mainly the thing that I’ve come to understand is the basic concepts of entropy and barrier free energy.
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Foy, Michael Ekker, Michael Gundlach, Michael Gutperle, Michael Hubbard, Michael Walsh, Michael Wright, Michelle Ho, Michelle Wu, Mickey Blake, Migael Strydom, Mik Scheper, Mikael, Mikael Niku, Mike Brixius, Mike Clark, Mike Clarke, Mike Kalmbach, mike lucido, Mike Makmur, Mike Matessa, Mike Mollman, Mike Oster, Mikkel Drogemuller Lund, Miles McGee, Mimi Rosen, Miranda, Miriam Golomb, Miriam Lylac, MirosÅ‚aw ArczyÅ„ski, Miruna Antonia, MK, ML, mm, Molly McGuire, Monica, Monica Barsever, Monica Barsever, Monica Nevins, Monica Pielage, morphtavist, Morris Stevens, Moshe Gelberman, Moz in Oz, msnjjguy, Mujtaba Morshed, Murrey87, Mylyrics, N T, N3XT, Naama Avramzon, Nada, Nan Zingrone, Naomi thomson, Natalia Luisa Hiller, Natasha Morales Drissi, Nate Tompkins, Nathalie Aubrun, Nathan Stitt, Neal McBurnett, Nebesu, Nellie Konijnendijk, Nicholas Currault, Nicholas Kroft, Nicholas Ting, Nicholi Gold, NICK PRITZKER, Nicole Mann, Nicole Sharpe, Nicole Sidebottom, Nidhi Krishnamurthy, Nils Deimann, Nils Fischer, nils mccarthy, Nimrod Muhumuza, Nina Wikman, Nisharg Shashtri, Noah Morris, Noel Arnold, Noel Yap, Noressa, Norman Jaffe, Norman Margolus, Nuri Banister, nvdhaar, Nègre Paulin, Núria Aguilar Góngora, Ocean & Dylan McIntyre, Oliver Andryszewski, Oliver Foulkes, Olivia Auferkorte, Olivia Waring, Olivier Gingras, omer shakked, OndÅ™ej Surý, Oquist Family, Orestes Kyriakos Poulakis, Osvaldo Pinali Doederlein, Pablo Soares, Pang Wei Koh, Pastafarian Woman, pat s, Patrick Dennis, Patrick Walling-Laperriere, Patrik Schmidt, Paul Adams, (continued)
Paul Christian Sommerhoff, Paul Coddington, Paul Foster, Paul Friz, Paul Laker, Paul Mac Eoin, Paul Nicholls, Paul Stansifer, Paul Wagner, Paulo Carvalho, Pchelovek1205, PDP11, Pedro Paiva, Per-Olof Björkman, Perry James, Pete R, Peter, Peter, Peter Christman, Peter Gray, Peter Hollens, Peter J. Mello, Peter Jon Kinsley, Peter Lawler, Peter Solfest, Peter van Gemert, Petra Mohr, Phabius, Philip Freeman, Philip Grove, Phillip Broussard, Phoebe Grigg, Phoebe Grigg, Phuong Tran, PhyzixGirl, Pietro Saccardi, PlayTheMind, Plotine Jardat, Porter, Preston Kemeny, Prof, ProfLover, pszNicx, Puymoyen Emmanuel, Quantum Cat, Quinn Norton, Rachael Haensly, Raj Movva, Raluca Pantilie, Rami E, Random Rail Fanner, Raphael Dos Santos Maia, ravenigma, Ravmatis Weinberg, Raymond Arnold, Reasoned Traveler, Rebecca Galvin, Rebecca Junell, Rebecca Livsey, Rebecca Moesta, Rebecca Rickly, Reed Hodge, Renaud Janson, Renee Conley, Renna Wolfe, Reto Stamm, Ric Flores, Ricardo Alvarado, Rich Holmes, Richard Bernier, Richard Boyd, Richard Haven, Richard Hoyer, Richard Martin, Richard Otter, Richard W Evert, Rick Groszkiewicz, Rick Levine, Rick Mann, Ricki Jay, rickyli99, RitheGuardian, RJ Merck, RK, Rob Baldwin, Rob Mattox, Rob Peters, Robert Becker, Robert Bermond, Robert Carpick, Robert Diamond, robert harrington, Robert Homer, Robert Keefer, Robert Mcbrayer, Robert Runyon, Robert Simms, Roberta D'Incà Levis, Robin Jost, Robinder, Robyn Gilliom, Robyn Ivey, Robyne, rodney elin, Rodolfo Maximiano, Rodrigo Caro, Rokaia, Rolf Timp, Ronald Knight, RoofPig, Rose Grumbine, Roshan, Ross, Ross Martin, Ruggero Cortini, Runa, Ruth Perry, Ruth Singleton, Ryan King, Ryan Smith, S, S. Faes, Sacha, Sacredvolt, Saffron, Sally Basile, Sam Burton, Sam Dick, Sam Elder, Sam Yates, Samantha Feldman, Sandra Magai, Sandy Ressler, Sara F, Sara Klips, Sarah, Sarah, Sarah Coe, Sarah Elder, Sarah Heile, Sarah K, Sarah Kingham, sarah latimer, Sarah Schultz, Schef Wright, Scott Cartwright, Scott Kallgren, Scott Key, Scott Moen, Scott Stevens, Sean Pendlebury, Sebastian Perez, Sebastian Roy, Sebastien Dutrisac, Sebi, Seleana Marie, Sensainikku, Seth Anthony, Seungeun Oh, sevtap nazime thurston, sg, Shahin, Shane Guthrie, Shane Jordan, Sharon Hilchie, Shawna Vacca, Shintaro Sasaki, Simon Waldherr, Simone Chiesi, Sinastri, Skyler Leigh, SlavicaK, Sleep Deprived, Snics, Sobakaisti, SoikerNahmu, soma jansen, sombra, Somesh Mukherjee, Sonya Sukalski, Soonish, Sophia Vandrey, Sophie Smith, Soren Walther, stacey falls, StarTalk Radio, Stefanie Hirt, Stephanie Guertin, Stephen Giandomenico, Stephen Hedrick, Stephen Johnson, Stephen Tihor, Stephen Tulip, Stephen Ward, Stephen Wyka, Steve Bryson, Steve Condas, Steve DiNardo, Steve Harding, Steve Hicks, Steve Messina, Steve Ruis, Steve Wall, Steven LaValle, Steven Veeneman, Stuart Hawkes, Sub Comediante, Summer C, Summit Sarkar, Sunny Walker, Susan Hersey, Susan Livingston, Susan R Lin, Susan Ray, Susan Speicher, Susan Wilson, Susan Witton, Susana Ramalhete, Suzanne Wakim, Suzy Dintzis, Sven Maihöfer, Sven Wijtmans, swiftyuki, Syd Hackworth, Sydney Gillman Wissel, Sébastien Auget, Tacos & Museums, Taekiro, taktoa, Tal Roitberg, Tanawat Tangsinmunkong, Tapio Rasa, Tara Morrigan, Taylor Sublett, teadrinker, Ted Pettus, Tegan, Teresa, Tero Keski-Valkama, Tero Suoniemi, Terrilee Perry, Thamar E. Gindin تامار گیندین, The Falbru Experiment, The Office Troll, The Schalick Family, Theo Cooper, Theresa van der Vlugt, Theresia, TheTallestJew, Thibaud Colas, Thomas, Thomas Baxter, Thomas Berli, Thomas Niebojewski, Thomas R Jackson, Thomas Risgaard, Thomas Roets, Thomas Stets, Thomas wasyluka, Thomas Wiecki, Thomas Willkan, Ti Eriksson, Tianxia Xiao, Tiela Black-Law, TierZoo, Tiffany M., Tillian Teske, Tim, Tim Marshall, Tim McElroy, Timothy Goh, Tina Johnston, Tobychev, Todd Furler, Tom Rawdanowicz, Tomohiko Tanabe, Tomáš Jurka, Tony Sheh, Tornado Tammy, Torsten Hvidt, TPen, Tracey Auerbach, Tracy Friedman, Trae Reinart, Travel Medicine Podcast, Travis Gerhardt, Travis Knowles, Trevor Diamond, Trey Beard, Trey Lathe, Trina Schroer, Trish Louise, Tristan Logue, truelove, Turadg Aleahmad, Tuyo Isaza, Tybie Fitzhugh, Tyler Anderson, Tyler Shaw, Ulys, Val Delane, Vampyricon, Vanity Nutrition, Vasiliki, Vasilios M Frankos, Venkatesh Murthy, Veritasium, Veronika Avtomonova, Vicky Loebel, Victor M, Victoria Huyer, Victoria Orevkova, Vik, Vikram S. Adve, Vincent Pelletier, Viren Ramchandani, Vlad D., Vlad Shulman, Vladimir Ivanov, VLENEN Qin, Wade Colborne, Walter F Smith, Walter Tross, Weeda Hamdan, weeedy, Wei Wei, Wendy Banner, Wendy Christopher, Wes Poteet, Wesley Unke, Whitney Sternberg, Will, Will Handy, Will Whitlow, Willi Galloway, William Buchman, William Gentry, William Penrose, William Pietri, William Sikkema, Willy Douglas, wls@rainfarm.com, Wolfgang Mehl, Xande Zublin, Xiaohu Hu, Xin Ye, Xinru Cheng, Y. Lee, yayayayay, Yigal Dozier, Yoann Rodriguez, Yonatan Bisk, Yonatan Shapira, Yonatan Zunger, Yu Matsuzawa, yuejingling, Yuh Saito, Yvonne Kwok-Lin, Zacary Thomas Dailey, Zacharyah Christian, Zhiqi Qiu, Zoe Ford, Zoe Stock, Zoltán Peczöli, Ãlvaro Arias, Éric Lvsk, Åukasz Stafiniak
So not only do you teach science but also rhyme it I salute you
What? 3blue1brown? The real one?
@@acapellascience now that's alot of thank you
I can't get over how good this is. I know I should just expect that from this channel by now, but I'm still somehow surprised.
3Blue1Brown Love your channel!
Waw one of my favorite UA-cam creator commenting on another incredible UA-cam creator! Awesome!
Also thanks for writing down my exact though on that ^^
You two are definitely the musical and visual overlords of science youtube :)
3Blue1Brown love your videos
3Blue1Brown your videos are amazing.
Admit it or not, it's much harder to make the song stcik to the topic, make sense, sound good, and have exactly the same rhyme scheme everywhere
He's a genius
It's a shame that someone so smart can't understand that such an advanced creature as a human can't happen without a maker.
@@johntaraba6713 Smart enough to realize you are a bullshitter
Don't forget that he has to animate too!
John Taraba if u listened to the shape of u parody by this guy maybe u’d realize
@@johntaraba6713 its a shame to realize that someone who has the potential to be really smart but doesn't know what the scienticfic method is.
“Program a nanobot” fits the rhythm of the song better than the actual lyrics lol
This is the glorious thing about parodies, often the new lyrics are more interesting and work better with the music!
madgrinchhatter madgrinchhatter I came back after listening to the original, damn it was unbearable. Also, is it me or does Dorothy sound more lively than the original singer ?
@Jackie Bruhn But these syllables make more sense.
Syllables lead to difference in intonation which matter to fitting to a particular melody. It is less problematic for less intonation incline languages like English but it's a problem nonetheless. Vietnamese for example, depend heavily on intonation to differentiate the words, and choose a wrong one lead to catastrophe...
@Jackie Bruhn they mean the words make more sensr
This is seriously incredible, amazing work Tim!
Two of my favorite channels interacting. Always smile when I see videos come from these two. As a biology major I love the videos coming from both channels with a passion. I always learn from watching yall's videos. I decided to write my microbiology research paper on CRISPR because of A Capelle Science! And I used info I learned from Tierzoo in a presentation I had!
OMG you watch him too!
I wonder how Nanobots and other microbes in general match up on the tier list.
Collab!!!!!!!!!!!!
Seriously. Please do a collab! I freakin' love both of your channels. I've been showing a bunch of my friends your videos, TierZoo and they love em as well. S+ on the UA-cam tier list, both of you gents. Entertaining AND informative! My very favorite type of content.
THE FACT THAT PROTEINS ARE ESSENTIALLY NANOBOTS JUST BLEW MY MIND!!!!
So is transcription and translation so its just nanobots making nanobots !! XD
And then we have prions...
so we have out there a set of nanobot caused diseases.
When u realize how easy it is to code organic matter and that they work in really life
Biology + coding + kinetics + statistics in real life
😱😳
Nanobots are just synthetic life and pseudo/protolife.
Combined with research being performed into reverse engineering enzymatic pathways we'll eventually find ourselves no longer limited by the small pool of naturally available enzymes, nor the need to program complex nanobots from the ground up, as we can just create the code for synthetic enzymes using RNA/DNA and splice it into yeast to create bioreactors for pretty much any chemical structure under the sun (and given 10 years have the ability to do it from your PC and a desktop printer for the cost of a single dose of insulin [which gets very cheap very quick when you can basically create it in a bottle of ~sugar water])
I love your nerdy versions of songs better than the originals. ❤️
Getting nerdgasms...
I know, right? I still haven't heard Despacito or Shape of You in their original form since these ones give both a musicgasm and a sciencegasm.
Honestly...
Joonas Mäkinen i was the same originally, but I heard “Shape of You” a few times this summer (mostly in stores). It was a weird and vaguely disappointing experience. “Molecular Shape of You” is much better.
Precisely.
She's got a great voice!
But she awkwardly smiles too much 😂😂
@@rohanghoshdastidar1047 i actually liked her grace... a lot
@@rohanghoshdastidar1047 doesn't matter. She looks so cute :)
@@rohanghoshdastidar1047 I dunno....if I was singing about molecular machines, I'd be smiling a bunch too! :3
@@rohanghoshdastidar1047 It didn't feel awkward to me at all. She just seemed like she really had fun doing this!
another solid hit, i'm a biologist with zero robotics background and i feel like i learned something! the side by side diagrams and animations of biomolecules was like a lightbulb moment. time to read all those references while i loop this video for 4 hours.
What where your final thoughts on this? I found it quite interesting, I'm only a novice though. Are the diagrams of biomolecules accurate? I'm trying to further understand the plausibility of this
Organic chemistry... Think you'd be willing to do one in the style of Linkin Park? Please?
Linkin Carbon
(Orgo Chem)
(It starts with)
Benzene, demystify
It's all about matter, check, verify
Carbon that binds, atoms aligned to combine
Explain the enzymes
(All I know)
“C” forms a covalent ring
Watch it show up in spectrometry
See it count up in the usual way
We build life this way
(It's so unreal)
Chemical math will show
Mass is conserved and entropy grows
Trying to hold on to electric charge flow
For covalent bonds to
(Molecule grow!)
Balance elements each side, reaction codified
It's a work of art
With this chemistry we'll eventually make 'em cleverly
Molecules that we can use
Without no harm
In the end
It's all about matter
Make cortisol
Or methanol
In the end
It's all about matter
Amines, the alkane chain
Nitrogenous molecules in aryl rings
Keep that in mind, atoms that bind
To fill valances with
(Shared electrons)
Despite assays, there's poor purity
Refine lab processes to maturity
Wash solutions, titrate and heat to precisely
Create a molecule
Things aren't the way they were before
Alchemy's dead, there's no magic in it anymore
Not that it worked back then
But it all comes back to “C”
(Orgo Chem!)
Know when you acidify an organic sulfide
It smells like a fart
With this chemistry we'll eventually make 'em cleverly
Molecules that we can use
Without no harm
In the end
It's all about matter
Make insulin
Or epinephrine
In the end
It's all about matter
Linus Pauling
It was you
Who figured out the code
Chemical bonds Organic chemists need to know
See the table
Read the code
Match them up
As you go
Fill the shells
Organic chemists need to know
Molecules that we can use
In the end, it's all about matter
Like building blocks
Our molecules
In the end, it's all about matter.
You need to make your own channel my friend. Cheers from a Biochemist.
They really need to see this
Which song is this parodying?
@@GamerFromJump It's says in the title...Don't bother looking it up, it's really not that good. Another example of parodies actually being better than the original.
Wow, this is really Fluorine Uranium Carbon Potassium-ing good.
This is amazing!
From Russia with love!
SciOne выпускайте видео уже
acapellascience and Scione are my favorite channels, you are awesome! :)
in soviet russia, a nanobot is meta-you
Here... you control the nano bot
In Soviet Russia... the nano bot controls you
@i6685No es que cosa es NUESTRA cosa
You are underrated, it would be kinda cool if you taught classes on UA-cam explaining parts of your songs and their meaning/history
I would learn a lot more about biology and chemistry if you did, because you need some Grad level information to understand all the references in your songs
Check out the references in the header of this video (click "SHOW MORE").
Seriously though, why is this channel not more famous?
Man, it's so fascinating, he should really do this.
Ya, his channel is too underrated . He deserves more than a million subs . But a fake video uploader channel got more subs .(You also know the name(s))
You never fail to surprise me with your clever position of words to mimic the original lyrics while also conveying a coherent scientific message. The harmonies are perfect as always!
Honestly, I don't mind the long wait times between your covers! Every time you put out a new cover, I spend days just listening to it on repeat - then I start researching the topic trying understand all of the lines in the song on a deeper level. This basically gaps the entire wait time - until a you put out a new cover I can start researching!
Thank you both for your awesome work! You're amazing!
These songs just got me rethinking the potential that are complex meta nano bot selves have
Is there a place that gives a basic explanation of everything in the song? I found an article about his Whole New Worlds song, but couldn't find anything for this song. (www.syfy.com/syfywire/whole-galaxy-new-worlds-capella-science-exoplanets)
Dorothy was utterly incredible, hope to see her again in some of these videos. Can even describe how excited I am to see you back!
She was perfect for this song. A good singer with a voice matching the original
Dorothy just has the brightest smile ever and I love her voice! The two of them go so well together with this song!
Quality over quantity! Totally worth it!
Putting the "conceptual" diagrams next to actual proteins used by microorganisms that demonstrate the concepts illustrated so elegantly allows the viewer to naturally connect the ideas in their head. Genuinely an incredible video.
You have no idea how long I have waited for this! Really amazing stuff, Tim.
same
idem
I dont even understand how you come up with this stuff, let alone create this masterpiece!! Keep up the awesome work!! You’re amazing!
he probably ate his greens and did homework on time...tats the reason
way better than real havana seriously lol
Exactly!! Havana oh na na?? I am a nanobot 10/10
ACE Gold oh you did not just say that
In this, the lyrics make way more sense
I really love the lady's expressions. So adorable
55 seconds and already one of my fave songs! My family is going to have this stuck in their heads for weeks!
This is FIRE!
I LOVE when an acapellascience video pop in my notification when i'm not expecting it, a few second in the video and... it's a masterpiece.
More video coming, it's a big YES, you deserve so much more views for these.
(sorry for aproximate english, french musical scientist here)
Not only is the song phenomenal, the animations make it actually understandable. What is beyond my understanding is not the topic but the awesomeness of this video!
EDIT: Holy molecule, there's even a reference list down in the description!
Am I the only one who has wished for more duets from these two? just wondering. Their voices blend so well.
the reference to closed and open circuits is crazy amazing
I love this! And I love how Dorothy looks like she's just having so much fun doing this!
How have I not found this channel before??
How does this only have a half-million views? This is legitimately a masterpiece. Somehow you keep raising the bar higher with each song and then proceed to crush it with the next.
The animations, lyrics, and actual performance is simply remarkable.
The best part is, it doesn't matter what order you listen to the songs; All your stuff from day one is phenomenal and sets the bar super high.
Forget the original this song just replaced the original one nice work man
This was incredible. Definitely worth waiting months for these songs.
Guess whos back
Scientist on track
No longer knowledge lack
Dope as crack
Won't break my neck
Rhyme.. check!✅
Great Song: Check
Original, informative and entertaining lyrics: Check
Interesting topic: Check
People who sing really, REALLY well: Check
Yup. Thats officiall the best video on youtube
I'm so glad you're back! Also, I wanted you to know that I picked up that book Endless Forms Most Beautiful because you recommend it in your Evo-Devo video. What an amazing read! I dont know much about biology so a lot of it went clear over my head, but even the small percentage that I was able to pick up on was incredibly eye opening. Thank you for doing what you do! I learn something new from each one of the songs you put out.
This channel is the most underrated science channel I ever came across! Hats off for the hard work guys!
Scientist being given the status and craz like Pop stars is a sign of humanity being going in right path.
Cheers to the community of shared future for mankind.
Humanity hasn't gone to any right path, only a portion of it did however.
The slow burn that it’s a song about cellular biology is still one of the top twists of all time
This sounds better than the original
There's lots of attention to details, which makes this so much more enjoyable
You are both so creative, smart and good singers💕😍 Awesome work as always👍 Good to have you back!
A year and a half ago I tried to explain to people what use could molecular machines be. Now I can add another application to that list -- a very catchy cover of an overplayed song. I love this, thanks, Tim!
Dorothy Andrusiak is amazing!! 😍
Thank you for this!! I’ve shared your videos a few times in the classroom, as often as applicable really. People have gotten better at making science fun but fun fades- you make it catchy and THAT’S the game changer. It allows info to transcend the moment into part of the thought process, part of the dialogue. We need more catchy science!
"NANOMACHINES, SON"
how grateful I am that you created this is hard to say
just know that I am beyond grateful
I am nanobot andy
i love the animated dancing robot so much. his expression always gets me :D at 1:01
Did you just rhyme energetic and setup....and get away with it!?! Genius! Can't wait for more content :)
nah, he rhymed
fuuuuuuuuuuuuuuuuueeeeeeeeel with throoooooooooooooooouuuuuuuuuuugh,
energetic with let it
and he just changed the tone to not have to rhyme setup with anything, otherwise its rhyme partner would have been load.
@@robinlindgren6429 the way I read it the rhyme structure is A B B A B C, with A being fuel and through, B being energetic, setup, and let it and C is load.
I would reject the argument that the first 2 B's aren't a rhyming couple as the BC pair are not a rhyming couple. This is because the "let it" line rhymes with the other 2 and you can't treat the last line the same since it breaks the B structure in both length and tone.
But that's just my analysis and your is valid too☺
Yup. Very nicely done half-rhyme/internal rhyme chain.
By using the right intonation, he created a partial alliteration and "rhyme" in the syllables "ener" and "se" and "get" and "set"
then builds on it with "let it", "ener" --> "se" --> "le", and "get" --> "set" --> "let"--> "it"
You see stuff like this all the time in good rap, but there they take it even further, they keep it going and even revisit a chain after a few lines etc.
This girl definitely brings something so special to that video, love her !
A whole semester of bio science in a single song, simply over the top amazing work. There should be a grammy/science type award for this. And as to add "the right fuel", the way she says: "break me down", infuses the entire song with sensuality, just brilliant.
My science teacher shows us these all the times, I'm addicted now..
As a student in Nanotechnology i can say I've actually learned a lot from the animations and explinations in this video, as well as your ed Sheeran chemistry video. Keep up the good work!
Cool science
ps: I fell in love with that woman
I actually am an organic material chemist. I work with another research academic chemist that has worked with the study of nanobots under her post doc. Her work dealt with the area hit at 1.26 minutes into the song.
Strangely the video it's not on your channel in UA-cam. I only knew that you release a song by bandcamp and acess the video from there. Great work as always.
Haha you caught it while still unlisted!
Wow, I didn't realize that was a thing. Thanks for teaching me that, speed demon!
Watching Dorothy looking like she was struggling to keep from busting out laughing was part of the fun of this video.
It's been exactly two months since this video came out. And I seriously expected more views for such a masterpiece.
This is my all time favourite of Acapella Science. And please let Dorothy Andrusiak sing more songs. She is great!
This is, indeed, so incredibly good! (and I did check each frame :p)
I wasn't sure about this one at first, but after listening all the way several times I'm completely on board. Absolutely one of your best, it's remarkable that you can make these amazing parodies with such a consistently high standard.
To plan a nanobot, you need to carefully map out the molecules that will make up the nanobot. Just like in living organisms, the choice of molecules and their arrangement will determine the nanobot's structure and function. Additionally, you must include motors for movement, similar to how motor proteins like kinesin and dynein operate in cells. These motors will enable controlled motion and navigation at the nanoscale.
Establishing communication signals is essential for the nanobot to interact with a central command or other components. This can be achieved by designing specific signals or chemical cues that allow the nanobot to receive instructions and transmit information.
The software and logic programming of the nanobot are crucial for its operation. Similar to how DNA encodes genetic information, the nanobot's programming determines its behavior and functionality. By programming specific instructions and logical operations into the nanobot's software, you can control its actions and responses to stimuli.
Controlling the movement of the nanobot is crucial because thermal energy constantly causes motion at the nanoscale. By carefully selecting the components and links within the nanobot's structure, you can limit the states it can assume and ensure controlled movement.
To make the nanobot effective, it is important to overcome barriers and minimize energy expenditure. By planning its design to navigate obstacles and conserve energy, you can optimize its performance. This can be achieved by incorporating mechanisms similar to ATP synthase, which efficiently convert energy for the nanobot's tasks.
In terms of information processing, you can design the nanobot to handle nano-informatics tasks. This involves creating structures for storing and retrieving data, incorporating switches and flip-flops that can be controlled chemically, photochemically, or electrically. By incorporating logic gates and decision-making capabilities, inspired by DNA and RNA polymerase, the nanobot can process information and perform calculations.
By considering all these aspects, you can create a nanobot that acts as an information scanner, capable of reading and writing coded data. This gives you the flexibility to program the nanobot for various tasks, making it a versatile and powerful tool. With its ability to perform complex operations, the nanobot can be seen as a synthetic counterpart to biological processes like DNA replication, intracellular transport, and mitosis, albeit on a smaller scale.
In summary, planning a nanobot involves careful consideration of its molecular composition, movement mechanisms, communication signals, and software programming. By drawing inspiration from biological systems and incorporating efficient design principles, you can create a functional and efficient nanobot for specific purposes.
Which program to use and how/where bwtter to join the process online/offline?
@tianyuema4797 thank you for that very helpful summary.
I will always remember Nanobot as the song that convinced me I needed to become an ACapellaScience Patron. So glad I did.
Bohemian Gravity introduced me to the channel years ago, but it was finding Bring Me A Gene a couple weeks ago that reminded me I'd never subed... I fixed that. And now this song is stuck in my head. You're welcome for the 1 year + reminder that it's STILL REALLY GOOD.
I knew that nanobots are incredibly small,but I didn't know that they were the level of molecules!
If they're making them so they function at the molecular level,then that's even more amazing!
Paras Yadav research organic chemistry! It’s amazing
Thank you Acapellascience. It's an outstanding video, one of best. I love the molecular tinker toys. The female vocals were a great addition. Thanks Dorothy Andrusiak!
This is spectacular! Catchy melody, interesting science content, eye-catching visuals, and clearly-inspired singers! Thanks!
I really like how you listed your patrons alphabetically by first name. It makes it so easy to find people I know who support you. And who still needs a little nudge.
Thanks, Tim.
Not sure why I was recommended this but it's amazing 😍
Great topic, images, music, and all skillfully put together with rich content. Dorothy's singing and delivery is fantastic. Love watching and re-watching this video.
How much time do you spend learning before starting to plan the songs? I would think you need to plan your songs a lot more than one would normally. Are other people part of that process? How about making the videos?
Anyways, you are part of the top layer of what Internet has to offer and I'm truly grateful for the work you do.
One of the best creations I have ever seen on internet so far. Keep up the good work
I kind of see this as capping off a trilogy that began with "The Molecular Shape of You" and continued with "Evo Devo". The first two are what life is made of, and how it got to be as complex as it is. And this would continue it by showing the genesis of artificial life.
I love the parodies here. Normally your own facial expressions jive with the tone of the song, but what made this really fun to watch were the facial expressions of your guest artist. She seemed like thoroughly enjoying the singing, unconcerned that she is being recorded. Priceless expressions. :D
Things I learnt from this video:
How to plan a nanobot
How not to plan a nanobot
Dorothy Andrusiak is actually a nanobot
This is probably the most amazing song on the internet. I really liked your old songs, but this is by far the best
I actually listened to these songs from Capella before I actually heard the original ones. Somehow, these songs are better than their originals
I didn't find any word to explain this song...I hear it many times but every time I got the same feeling.. love it..
Tim Blais is alive! :D
I found this video in my sub box 2 h ago and have watched it a total of 10 times so far, only interrupted by some of your older videos.
Amazing work as always, and Dorothy was awesome too!
A Capella Science videos? I'll Havana-ther!
i'm in 2nd semester biotechnology and this video just blew my mind, great job!
This channel is going to become the next ERB in popularity
After mercilessly devouring the competition... this is now my favorite channel... Keep it coming!
Greetings from Brazil! For sure it is pretty much better than the original one. You're amazing Tim! Me and my friends from college just love your channel. Thanks for being awesome.
Im on the programming side of things if you want to understand this more I reccommend learning what a turing machine. Any system in which you can create logic gates and wire thier outputs into the inputs of other logic gates you can create a computer. Sebastian Lague had a great series in which he creates and explores the purposes of rudimentary computer componets and it comes together quite nicely how you could create a computer with theese simple tools.
J'adore, c'est génial !
English please
L3 G33K Ne t'en fais pas de lui. On peut te comprendre.
Translation: “I like it, it’s awesome!”
The first one. The second and third French comments are beyond me.
n°2 (Isaac) : «do not worry, we can understand you»
n°3 (Timothee) : It is very Reblochon by here tell me > Local expression to say that there is a lot of French in the area ;) (Reblochon is a French cheese)
La chanteuse est Québecoise, je crois.
I don't know what is incredible, the song, the singer, the concept (I mean it is literally randomness + a lot of times to evolve) or the people find out the concept. Probably all of them
A year and a half later... This is still stuck in my head.
I absolutely loved this!
I previously commented on a flaw I believed to see at 2:07, but the way "allot" is used here is actually correct.
This is amazing! No wonder this video was recommended to me.
Aaaaaaahhh congratulations!
Dorothy looks so happy to do this °_°
I am so happy you are back!!!
Glad you had a great summer, sounds fun.
Dude you are AWESOME
I'm not at all a biologist - I'm a software engineer. But this has made me rethink how I write software
every time you do a video about something i dont know, as this one, i go mad to find more about the subject of the video. keep the great job man
We need to give him a nobel prize in education and science motivation!
I absolutely love the work on molecular machines, it really excites me as a chemist. Especially Fraser Foster's work, as a fellow Scotsman I am really a fan of his work and it's nice to see this area of science explored. Fantastic work as usual!
3:10 *I am a nanobot* , I got goose bumps. didn't you?
When you are good at rhyming, music, and advanced science topics all at the same time.
I know enough to understand the science now!
Lol, I just did a short thermodynamic unit in my first year Uni Biology class. I’m not an expert, I just understand the basic theory. Mainly the thing that I’ve come to understand is the basic concepts of entropy and barrier free energy.
The acapela in 0:01 is just so satisfying to see them sync