GDNF and fast walking self-challenge (Parkinson’s Disease)
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- Опубліковано 5 лют 2025
- While GDNF is a relatively new discovery, it may hold the key to hold back or even reverse Parkinson's Disease symptoms. In this video I invite everyone to take part in their own personal GDNF challenge.
Blog page - www.lifewithpa...
Resources:
John Pepper video - • REVERSING PARKINSONS’ ...
Parkinson's UK Study - www.parkinsons...
www.parkinsons...
GDNF rat study - www.ncbi.nlm.n....
www.nature.com...
healthunlocked...
• A Reversing of Parkins...
• GDNF: Being part of a ...
Check out our website! - lifewithparkin...
Connect with us on Facebook - / davidslifewithparkinsons
I've included some helpful links in the video description.
Link to Rouge Care Canada - rougecare.ca/?...
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Hi, David
From the first minute I saw your video, i saw that you were calmer, with a lot less dyskinrsia.
My mom walks for 5 days now und she already saw improvement in her left leg.
❤❤❤
Hi Elena, thank you for sharing this positive feedback. Your comment made my day😊😁😃
Hi David, great video , thanks. I read somewhere of a study done by pwp getting noticeably better results by 'forced' cycling, ie riding on a tandem bicycle with a non-pwp. The results were very positive. I am not able to find a tandem or a partner to ride with so decided to look for what I thought was the next best thing, a treadmill. I tried it out at a gym first and I enjoyed it. I found a well priced 2nd hand one and I now do fast walking every second day for 30 to 40 minutes. It is stable, I am not dependant on the weather, and I can walk faster on the treadmill for extended periods than I would if I was walking outside. I do between 3 and 4,5km every second day. It definitely helps suppress the PD symptoms, gets the joints moving, gets the heart pumping and lungs working. Cheers Jez
Hi Jez, thanks for the memory prompt. I remember reading about forced cycling as well. I found the treadmill good also, especially in the winter. The only negative was that the surface of the treadmill never changed, so certain muscles rarely got used, like you might use while walking around a lake in a park where there are uneven surfaces. 😊😁😀
I’m sooo glad you saw the John Pepper video. I too have Parkinson’s (since 2013) and was shocked when watching how it made a lot of sense but that I had never heard of GDNF before. I asked my movement disorder doc and she knew of its benefits but said there had not been success at creating a delivery method that effectively crossed the blood brain barrier. In other words a medical delivery method had not been effectively solved but John Peppers point was that the body itself can create its own excess from the walking that properly gets it where it needs to go without having to replicate it a different way. I’m doing the walking too and also liking the results so far. I like my doc but the docs I find mainly discuss meds and not specifics of exercise as you mention. I truly think there’s something good here and try to share with Parkinson’s friends but many only want to listen to a doc and can’t trust a new idea on a video that may be buried in the vastness of You Tube. Wish you continued success here and happy to discuss more.
Hi Stevy, the John Pepper video was amazing, and very welcomes. I have been trying for a while to find that SPECIFIC exercise that benefits PWP's the most. Was excited when I learned fast walking was tied to increased GDNF. At least now there is some proof about a SPECIFIC activity. Thanks for your comment.😊😁😃
A very important presence on UA-cam, excellent content.🌞
Thank you for your very kind and encouraging words and for supporting this channel ❤️😃😄😊
Life with Parkinson’s, nice video keep it up
Thank you very much😊😁😀
Thank you. I appreciate your encouraging and informative video. Best wishes.
Hi Keith, glad it was helpful! Thank you for supporting the channel.😊😁😀
I look forward to your next post!
Thanks Elaine.😊😁😃
Cool! I will check out your blog page and follow along. ;)
Thanks Nancy. Just started the blog page yesterday when I woke up and re-wrote the entire episode lol. This is much better, but I need to stop doing that!😊😁😀
You are notably looking fabulously healthful today!
Moments are notably unique...and everchangingly unchanging. Sometimes we need to rest, sometimes we need to suckerpunch that punchingbag, and sometimes we need to embrace our sassypant side and shove that ol' bootie in the air an' swing it all around!!❤❤😅😂😊❤❤
Thanks Rose, been feeling well lately. There's a time for everything, even feeling good when you have PD. Thanks for the reminder.😁😊😀
Sounds promising!
Thanks Jeremy!😊😁😀
I heard Emory in Atlanta has had a 12-year program using Argentina Tango to help movement
If you see the results please let me know 😃😊😀
It's good to do all sorts of exercise i think. There is something called Interval walking training that is a form of hiit that you can do while you walking. You can look it up, it originated from Japan.
Hi Peter, that sounds like the run/walk run/walk etc.. that I did for a while. I will check it out thanks.😊😁😃
Hey buddy great job ❤ in
My opinion any high intensity exercise is good and slows the progression of pd. Number 1: boxing!! High intensity and volume with moving around the heavy bag, and running on the spot while throwing straight punches. Gets the heart pumping as well lifting weights. Walking and running, sure..baby steps until you can push yourself to the maximum. I recommend while “on” you can see sonw of my boxing workout on my channel ❤❤❤❤
Thanks GoPro, yes any hi intensity exercise is good to do! Love your videos on your channel and recommend them to everyone!😊😁😀
Please consider a carnivore diet. ❤
Thank you for supporting this channel. I have tried to eat more protein but it keeps interfering with my medication but I am trying 😃😄😊
@@LifewithParkinsons Excellent to hear. Eliminating all carbohydrates, sugar and seed oils is a start and introducing natural animal fats. High fat and protein to rebuild. You're in my prayers. 🌸
@@BlackButterFlyTongue that is exactly what I have done I have eliminated almost all carbs except from fruit and vegetables. Thank you for your prayers. 😄😃😊
David , what is the therapy you think worked best for you?
Hi, that's a difficult question to answer. I have a whole playlist dedicated to that. If I had to pick it would be exercise. Here is link to the playlist on my website. www.lifewithparkinsons.ca/post/dave-what-has-changed-in-your-parkinson-s-treatment-plan
how fast is "fast"?
I love this question. "Fast" is your top speed that you can maintain for 1hr straight.😊😁😀
So it took 8years to come off his medication. He makes it seem he was on a whole lot of meds. He was only on selegiline, he stopped l dopa after 3 months as it did nothing for him. He told me no one had been able to reverse their PD as he had. You will find all the people he mentions as having good results are early in the disease process.
Hello, I did not realize that he was not taking very much L-Dopa. Thanks for the info. I'm going to keep going on it. The walking is helping get out of the house daily at least. 😊😁😃
Hallo David, ab welcher Geschwindigkeit und nach welchem Zeitraum fängt der Körper beim Laufen GDNF zu produzieren? Liebe Grüße aus Hamburg
I am not sure, but here is an observation from one of the studies.
"Higher intensity exercise (>30 m/min) can increase glial cell line‐derived neurotrophic factor (GDNF) protein content in fast‐twitch myofibers as well as induce changes in the neuromuscular junction (NMJ) morphology. These findings help to inform exercise prescription to preserve the integrity of the neuromuscular system through aging and disease."
Here are the links to the resources I used:
John Pepper video - ua-cam.com/video/YkCN5COXjbY/v-deo.htmlsi=hBEOOeeAkhhTd3wP
Parkinson's UK Study - www.parkinsons.org.uk/news/gdnf-clinical-trial-offers-hope-restoring-brain-cells-damaged-parkinsons
www.parkinsons.org.uk/research/research-blog/research-explained/gdnf-and-other-growth-factors
GDNF rat study - www.ncbi.nlm.nih.gov/pmc/articles/PMC3966253/#:~:text=Higher%20intensity%20exercise%20(%3E30%20m/min)%20can%20increase%20glial,of%20the%20neuromuscular%20system%20through%20aging%20and%20disease.
www.nature.com/articles/s41582-019-0180-6
healthunlocked.com/cure-parkinsons/posts/138242010/have-you-tried-fast-walking-yet-if-so-has-it-helped-you
ua-cam.com/video/pfMeAxENq8c/v-deo.html
ua-cam.com/video/NGgqr_gu9lc/v-deo.html
Hello, I am not sure. Here is a good observation from one of the studies.
"
Higher intensity exercise (>30 m/min) can increase glial cell line‐derived neurotrophic factor (GDNF) protein content in fast‐twitch myofibers as well as induce changes in the neuromuscular junction (NMJ) morphology. These findings help to inform exercise prescription to preserve the integrity of the neuromuscular system through aging and disease."
Here are links to all of the resources I used.
John Pepper video - ua-cam.com/video/YkCN5COXjbY/v-deo.htmlsi=hBEOOeeAkhhTd3wP
Parkinson's UK Study - www.parkinsons.org.uk/news/gdnf-clinical-trial-offers-hope-restoring-brain-cells-damaged-parkinsons
www.parkinsons.org.uk/research/research-blog/research-explained/gdnf-and-other-growth-factors
GDNF rat study - www.ncbi.nlm.nih.gov/pmc/articles/PMC3966253/#:~:text=Higher%20intensity%20exercise%20(%3E30%20m/min)%20can%20increase%20glial,of%20the%20neuromuscular%20system%20through%20aging%20and%20disease.
www.nature.com/articles/s41582-019-0180-6
healthunlocked.com/cure-parkinsons/posts/138242010/have-you-tried-fast-walking-yet-if-so-has-it-helped-you
ua-cam.com/video/pfMeAxENq8c/v-deo.html
ua-cam.com/video/NGgqr_gu9lc/v-deo.html
I am not sure, but here is a good observation from one of the studies.
"Higher intensity exercise (>30 m/min) can increase glial cell line‐derived neurotrophic factor (GDNF) protein content in fast‐twitch myofibers as well as induce changes in the neuromuscular junction (NMJ) morphology. These findings help to inform exercise prescription to preserve the integrity of the neuromuscular system through aging and disease."
Please check the video description for all the links to the resources I used.😊😁😀