Mechanism of Drug Addiction in the Brain, Animation.
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- Опубліковано 14 жов 2024
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Addiction is a neurological disorder that affects the reward system in the brain. In a healthy person, the reward system reinforces important behaviors that are essential for survival such as eating, drinking, sex, and social interaction. For example, the reward system ensures that you reach for food when you are hungry, because you know that after eating you will feel good. In other words, it makes the activity of eating pleasurable and memorable, so you would want to do it again and again whenever you feel hungry. Drugs of abuse hijack this system, turning the person’s natural needs into drug needs.
The brain consists of billions of neurons, or nerve cells, which communicate via chemical messages, or neurotransmitters. When a neuron is sufficiently stimulated, an electrical impulse called an action potential is generated and travels down the axon to the nerve terminal. Here, it triggers the release of a neurotransmitter into the synaptic cleft - a space between neurons. The neurotransmitter then binds to a receptor on a neighboring neuron, generating a signal in it, thereby transmitting the information to that neuron.
The major reward pathways involve transmission of the neurotransmitter dopamine from the ventral tegmental area - the VTA - of the midbrain to the limbic system and the frontal cortex. Engaging in enjoyable activities generates action potentials in dopamine-producing neurons of the VTA. This causes dopamine release from the neurons into the synaptic space. Dopamine then binds to and stimulates dopamine-receptor on the receiving neuron. This stimulation by dopamine is believed to produce the pleasurable feelings or rewarding effect. Dopamine molecules are then removed from the synaptic space and transported back in to the transmitting neuron by a special protein called dopamine-transporter.
Most drugs of abuse increase the level of dopamine in the reward pathway. Some drugs such as alcohol, heroin, and nicotine indirectly excite the dopamine-producing neurons in the VTA so that they generate more action potentials. Cocaine acts at the nerve terminal. It binds to dopamine-transporter and blocks the re-uptake of dopamine. Methamphetamine - a psychostimulant - acts similarly to cocaine in blocking dopamine removal. In addition, it can enter the neuron, into the dopamine-containing vesicles where it triggers dopamine release even in the absence of action potentials.
Different drugs act different way but the common outcome is that dopamine builds-up in the synapse to a much greater amount than normal. This causes a continuous stimulation, maybe over-stimulation of receiving neurons and is responsible for prolonged and intense euphoria experienced by drug users. Repeated exposure to dopamine surges caused by drugs eventually de-sensitizes the reward system. The system is no longer responsive to everyday stimuli; the only thing that is rewarding is the drug. That is how drugs change the person’s life priority. After some time, even the drug loses its ability to reward and higher doses are required to achieve the rewarding effect. This ultimately leads to drug overdose.
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That's amazing 😢😍. So happy for you now. I'm an addict from the UK. I was so low I took hard drugs for 15 years. I turn 2.5 years abstinent on the 21st of January ❤️🙏.
Plz help me 2012 parkinsas daseses using elaj Lovedopa dally using plz help me
Congratulations! I hope you a good recovery.
Agreed . When you give up on fighting addiction then you give up on life and caring about family. I have friends who have gone years without relapse and it has been due to therapy and a strong relationship with God
You wanted to change.
When I stopped drugs and drinking, I got excitement and pleasure elsewhere. Like helping people. Doesn’t give you a hang over
REAL HAPPINESS POG
Why do we need excitement and pleasure,,,
@@lightbeingpontifex Are you depressed?
@@lightbeingpontifex ?
@@lightbeingpontifex we need to be excited over the normal activities we do in everyday life or else we'd never have the motivation to do them.
I am in full time recovery from cocaine addiction!! I suffered with horrendous cravings regular! understanding how addiction works with the dopamine was a key ingredient to overcoming my addiction, once we understand something like addiction and how our brains reacts, it can help us to move forward. ih hope everybody is well and at peace :)
Hi what are you doing for your recovery?
Every time I get the urge to use, I'm going to try to remember to play this video.. this way I can mentally snap out of it. Thank you
Plus getting into a support group right? I know that helped me tremendously to be around people who understood my brain! Not only that they had Solutions on how to cope with it!
How u been?
So how are you
Overdose (especially lethal) actually occurs most often after a period of sobriety. With heroin, it's the respiratory depression that most often results in death, and tolerance to that effect develops along with a tolerance to the high. It's the decrease in tolerance that occurs during sobriety. An ensuing relapse where the user attempts to use roughly what they were prior to detox has a much more marked response. This can happen in as short a span as week or two as well.
Thank you so much for sharing this. I was talking to, and went out with someone with whom I felt a genuine connection. We went out on a Friday. I didn't know that the day before was his 1 year anniversary of sobriety. I just found out that the following weekend, he passed due to a fentanyl overdose.
The week leading up to that his communication seemed sporadic and short - completely different. The last thing he said to me was,."I definitely want to see you again soon.... Still thinking about what a great time we had."
That was Wednesday and I never heard from him again. I couldn't understand why. Then I found out he'd passed the following Sunday.
He had a good heart. He was planning for the future. He is in Heaven now. He knew the Lord. There is no more pain or suffering for him. But he was special.
My best friend died 12.5 years ago from injecting heroin and drinking alcohol. The heroin on its own would unlikely of killed him and the alcohol on its own would of killed him. But the both together caused him to die. Very sad 😔. I remember it like it was yesterday. I continued to take drugs for many years after that. I finally stopped in 2020 when I went to treatment. And have stayed clean since 🙏❤️❤️❤️
That was presented and explained so well. Thank you.
Incredible video. All the reading I do I still found it hard to really grasp the process, but this video explained it completely in a nutshell! Wish I found it sooner
Overdose was just another word tossed around in my vocabulary, now knowing what causes it brings on a whole different meaning that makes perfect sense.
An overdose is typically caused by a central nervous system depression or over stimulation. The brain stem, the part of the brain responsible for giving signals to do things we do without thinking (breathing, blinking of eyes, etc) is depressed so much bc of the over saturation of the receptors that the brain cannot overcome it, it cannot monitor the carbon dioxide in the blood stream which would make one take a deep breath... the part of the brain needed for basic functions to sustain life become numb, incapacitated and a person sadly stops breathing bc the part of the brain that tells it to breathe is "unconscious too." So my entire point of responding to your comment specifically is to clarify that it isn't the dopamine receptors that cause the overdose, it is the nervous system depression due to the lack of brain activity/function: what causes a person to stop breathing... if that makes sense, yes its the catalyst of causing the surge of chemicals that depresses the brain, but it is the symptoms that are caused by that oversaturation of chemicals that causes the death, the overdose... the ability to control or be aware of ones utter and absolute lack of oxygen and need to breath without outside intervention. which are the consequences of too much, 99% of the time done accidently I should add. And typically, after a period of sobriety as @RespectThis said, the user thinks they can use the same amount, but it overwhelms the body and the person typically stops breathing due to lack of tolerance and also not being told/being fooled/poisoned some may say by what drug they are taking bc the pills/fentanyl out there is in the form of pharmaceutical pills,... you can look them up on a pill identifier website online and it will tell you it's something else. We are being lied to as to what is in the drugs, thinking it's one thing and being told it is, but its counterfeit, they are not real opiates from a licensed pharmacy, the pills contain solely fentanyl now a days. Fentanyl is 100x time more potent than heroin... People think they're doing heroin, but are given fentanyl unknowingly, and a very small amount will cause an overdose unintentionally... is so sad and so scary. I just wanted to clarify what causes the overdose and am not hating on you or correcting you or judging you. Thanks for trying to understand for real!
@@kristinlasart5153 what a wonderful explanation! Thank you so much in taking the time to write that all out. Know that it helped me tremendously! And just beginning my journey and understanding my brain. I will add that I am sober I don't use alcohol or hard drugs
Pain, abusers, poverty, loneliness…..
So many causes for addiction
I hate that addiction starts as a way to fix a problem…..and then it never let never goes away no matter how hard we try
What a nice simple amazing video explaining the reward system in our brains.
This video just might have saved me on my exam today
bet you didn't pass
xD
You failed
How??
Sure you could’ve just popped some Adderall and that would have worked also 😅
I just want to get this off my chest.
My dad is a homeless drug addict. He smokes crystal meth and fantanyl. He sleeps on my moms patio even though she has a new boyfriend. We all feel bad for my dad but there is nothing we can do for him, he made his choice, its past the point of no return. But its sooo painful. It hurts my heart and makes me cry. It hurts so bad.
❤
Jeez cant you help him???
You can take him to a rehabilitation centre incase you have them in your country. He is suffering from substance use disorder. In fact you can take him to a mental health unit because it's what we do here in my country Uganda 🇺🇬
Lock him a room and beat his ass.. instead of seeing him dye on your watch
🥺🥺🥺
Yup addiction is a family destroyer 🥺🥺
I watch these video to learn how drug abuse effected my body and to start clean. 5 years clean from heroine
Fuhhhh good
Congratulations
Outing addiction is more happiness than being lust deep in addiction
Yes
Most addicts know that as well but they still continue which shows how important mental health is.
How do I quit need help
@@moneymaccc its all about who u surround urself with and willpower
Well by the help of almighty Allah I have stopped taking it and got happiness
Holy shit this video was a lifesaver when it came to my assessment on the chemical effects of addiction. Keep up the amazing, well thought out concise videos.
Very easy to understand. Good video!!!
I experience this video real life... so I can understand this video everything
THIS! IS! INCREDIBLE! Thank you so much
Thank you for providing the narrative text of the video in the notes.
tall explain things so well, this makes sooooo much sense wow!
In Hong Kong there is a Christian rehabilitation centre, ppl go there and live there under some strict rules, need to read, pray and discuss bible from 5.5 hours a day, sleep early and wake up early, when newcomers feel sick of wanting drugs, ppl there would pray for them and read bible to them and give them hot water bath, this center is a successful center for helping folks to quit addiction of drugs.
The rehabilitation center is on an island so folks cannot leave easily. It did help ppl to quit drug addiction. America should have center like this.
It won't get you straight away. but it will get you.It's a one way ticket to Nowhereville.
Now THAT is a sobering yet simple way of advising us to stay away from drugs..
HEY Oiii you will defeat this!!!! When we have a relapse it seems impossible to change but it doesn't really change our fight, the brain often creates things that seem very real but they are not and WE WILL WIN It seems impossible and we will never win but we will and I just KNOW that you are such an INCREDIBLE AND GOOD AND KIND person this world needs people like you, it seems that this fight is endless and frustrating but you WILL WIN, dragging yourself on the ground if you have to but you will win and that's a fact ❤️❤️💗 💗 even if it always seems to remember that you will never be alone in this battle and you are SO AMAZING men and women, even when we seem to be at rock bottom we climbed everything, I didn't believe that but I went through it AND YOU ALL HERE WILL WIN, AND NOW I'M SO MUCH PROUD ❤️❤️❤️ LET'S WIN, I went through it and it seemed like it would never pass and it was a sea of darkness but there is always light in this environment and with time we see that we are capable and we are always fighting❤❤ LET'S GO ACHIEVE EVEN WHEN IT SEEMS IMPOSSIBLE LET'S GO
❤
Pain is as regular as addiction. Taking pain mediation reduces (but not removes entirely) pain. When the pain subsides, like when one is sitting quietly, there is no urge to take pain medication because one is not prompted to do so, by the "usual" pain. Only when pain starts up again (from moving the body or being mobile (of joints) ) does the desire to take pain medication restart. It is not prompted by anything other than the "pain returning". - in a way, pain is an addictive event, always starting-up when activity happens again. - Have A Nice Day.
I have severe chronic pain anf I do take medication for pain. I only take a very small dose per day so that I am not bedridden and can take care of my son and do a bit of work around my home and have some quality of life. I wait till pain is extremely bad before I need to collapse to take it. I am prescribed more but don't use it. I wish I didn't need it but the pain is so bad I always think of taking my life due to such poor quality of life. It's been 41 years and after a while any Human would have thrown in the towel with 24/7 pain and no sleep. I have the feeling but I'm alive and I stayed to take care
of my boys when their mother ran off with her boyfriend. I am lucky I'm alive and I am grateful to all the pain specialist who try to help me.
Pain medicine was created and intended to help people manage pain. Creating more laws and regulations that prevent doctors from legitimately prescribing necessary medication is doing nothing but creating a chronic pain crisis. Ppl who do this illegally manufacture it themselves. They sell it themselves They do not obey laws - obviously. Putting doctors in prison (YES, this is happening) and limiting the amount of pills a pharmacy can carry (which results in patients being unable to fill legitimate prescriptions), enabling pharmacists to undermine doctors, has resulted in ppl committing suicide because they can't deal with the pain day after day. They have little to no quality of life. THAT is the result of the "opioid crisis."
@@youknowcrimedontpay9257 You are so brave! You are so incredibly strong even though you feel weak :) No one who has never known how much strength and mental resilience it takes to stay day after day and fight the baffling disorientation, noise and obsession that wanting to die causes...and how isolated and weak one feels as they fight the voices and tsunamis of lies alone , to fight mental illness alone but instead of buying into others fears and hateful opinions, the greatest gift we can give ourselves is trying to start recognizing the strength it takes to stay solely for the well-being of someone else. How much guts, balls, gall it takes, the amount of strength it takes a person who wants to die every day to instead stay solely out of concern for how someone else will be affected by their absence... That is courage my dear. That is unconditional, selfless love actually :) I see you!
Brave heart, in my humble opinion and experience, I think you should bless those that know and love you and commit to sticking around a little while longer honey. It gets better (Cliche I know), it really does. Life is so overwhelming and suffocating until one day it's just not... and life and kids and animals; anything that you fought through the unbearable pain for: everything that you stayed for truly becomes the natural high of life and the obsession that you once were a slave too and which required you to seek the necessary relief for... abated pain if only for one-minute would be ecstasy, yes? ... It's going to happen for you, just dont give up. The world needs your courage and love and light. Please stay awhile and remind yourself what an incredibly brave and bad ass person you are for still showing up in life despite it all :) I see you and I think you're pretty amazing. the kids you spoke about are SO damn lucky to have you and will benefit from your triumphant wins that you're destined for.
@@youknowcrimedontpay9257 how are you doing now maam?
This was explained so well!
Quite a few years ago there was a BBC lunchtime news feature on a trial to cure chemical addiction. It was reported to be +90% effective in the trials so far.
It worked by measuring the frequency of the drug and then passing electrical current of the same frequency through 2 electrodes the patient held in their hands.
This caused the body to quickly start to excrete the substance out through the skins pores.
The clinic room even had an en-suite shower to wash it all off.
I forgot all about it for years and now can find no mention of it on the net.
I wish I had recorded it but I had missed the very start of the feature and thought I’ll just record the evening news and get the whole thing. It wasn’t on the evening news however.
🤔 How can we serch then?
the body would excrete the substance out through skin?? that's crazy intresting, would love to watch this . if u are somehow able to find it please comment
Lol that sounds more like a fictional movie. Curing addiction isnt as simple as just removing the drug from the system. Also, that sounds like fiction, the mention of the "drugs just seeping out of their pores" part.
@@sakomardirosian3439 this does not exist
It's called a bridge device
It's crazy the effects drugs have on a person. I injected amphetamine/meth for 11 years and 5 years before I took a lot of cocaine. Also the last 2 years a lot of crack cocaine as well as amphetamine. I've been abstinent from all drugs for 2.5 years. But I still have strange twitches and tics that I think are from my drug use. But it doesn't bother me that much I'm the happiest I've ever been. The only times when I really struggle is when the paranoia and anxiety hit me. But its not as often anymore. If your struggling with addiction. There is hope. Trust me if I can stop so can you 💯 🙏❤️
You're awesome currently im Dealing with addiction to tobacco and bipolar meds
@Nancy thank you nancy ❤️. Hope you can kick your addiction. You can do it 💪 ✨️ ❤️
@@chrisbee487 thank you Chris❤
@@Nancy-ow9wy ❤️
Hell yeah guys! Fuck that shit!
I am an addict and I literally feel like I can't stop, it's making me feel suicidal, as an addict this really is a disease which I feel is no cure for, NA and AA does not work, I've tried everything and nothing can get rid of my addiction
Salina Sappora weeds da best
You need a dopamine detox
Wellbutrin maybe
u should consult a better doctor seriously not joking
You need a burning desire to change your habit and sleep for 3 weeks and eat drink (water)
As an addict I can watch this, is still does not register in my brain that this is bad, addiction overalls everything, this is why the government need to do more or use me as a guinea pig to come up with some results to help addicts like me and others out there.
True...Most of times understand and feel its bad but at the end or few minutes later totally forget.. and one day again like first thing i h ad mentioned up there... We understand , we know but ,not registering on brain by anychance..
What is bad,,,? Something that everyone else says,,?
Try getting clean for 6 months.
@@larrytate1657 one day at a time. Next thing u know. Ots one month at a time
"Think about how stopping this will benefit you in the future. If it isn’t enough to convince you everyday, you’re doomed."
This is drug addiction!!!!!! So accurate and so true the reason why we end up using is irrelevant
5 years off of heroin and i have np emotions at all nothing is worth doing. I feel like a robot for 5 years with no enjoyment in eating or achieving or in socializing and no sex drive or interest in anything at all. I believe it permanently altered my brain by using IV heroin for 10 years. Nothing could compare to the high it did give me
So ur thinking of trying again?
Holy shi that's bad
how u doing
I love how this was sampled in a dubstep song
The webs we create around ourselves need to be unwound. If you have ever untangled a ball of string, you know that yanking & pulling only makes it worse. You need to very gently & patiently unravel the knots. Be gentle & patient with yourself as you untangle your own mental knots. Get help if you need it. Above all, love yourself in the process. The willingness to let go of the old is the key.
That is the secret.
Yesss
Proteins made from micro organisms , such as bacteria and yeast, which are called single - cell proteins . Yeast has been used in making single cell proteins as food, such food is also rich in vitamins.
Very nicely explained. Thankyou❤
Been clean of heroin for 2 months now I’m glad I’m happy I still smoke weed but stopped smoking and now I’m smoking cbd cigs to stop smoking weed, it’s just the drinking rn is kinda tough
Very clear explanation
Very useful
Thank you
You are welcome!
@@Alilamedicalmediathanks very much
Do the chemicals in the cigarette also play a role in how nicotine affects the brain?
What about vaping e-liquid that has 3mg nicotine in it?
It's not as bad as smoke in the lungs, but does it have the same effects as cigarettes with nicotine even though it doesn't have all of the other chemicals?
Not sure if there are conclusive studies about other chemicals in the cigarettes. However, as long as you consume nicotine, it has the same effect on dependence. The dose may be lower and no smoke is better than smoke, but long-term studies would be needed to access the effect of e-cigarettes.
Cigarette nicotine is free base due to tobacco being treated with some gnarly additives to make it a better buzz, vape liquid I've seen usually uses nicotine salts.
Scientists need to make a drug for addicts to help stop their addiction and those impulses that make them want to use, I've literally tried everything and need help so badly.
To forget a drug you use another drug .. by the end of day maybe the new drug will be addicted
@@mr_nobodyyy_ no ,that does not work, the whole point of addiction is wanting to stop so badly but it's an everyday struggle, , the cycle of addiction, the struggle and the impact it has on a human being
When you feel a craving or are finding just recognize the feeling and look at the thoughts but don't act on them,,, and think / do something else,,,
I hope you're doing good and are sober now❤❤❤
great video!
I am a maladaptive daydreamer and I am tryna get over my addiction to daydreaming 🌹🌹🌹🌹🌹🌹
Me too
Very nice information.
yeah, very good explanation
It was really awesome presentation of drug addiction treatment. Rapid opiate detox is a relatively new method of treating opiate addiction. Because it can be accomplished quickly and privately, opiate rapid detox is an attractive option for people who want to avoid the fallout of having their drug dependence publicly known.
Do those prone to addiction have lower natural levels of dopamine or dopamine receptors? I struggled off and on with addiction. Since I was a child I've had a flat mood and seldom smile or feel contentment. It was always noticeable to others long before my addiction. Try as I might I have never felt the reward the video talks about. People would even get angry with me for not feeling happy. When I was a toddler my older brother used to humiliate me and hit me whenever I looked happy. He would snuff out my happy feeling. It went on from age 3 until I was 10. The psychologist told me I missed the developmental phase needed and that what my brother did was psychological torture common in psychopaths.
YES!! I was put on psychotropic medication at age 5: Ritalin. So my brain chemistry, my brain function, my tiny brain that doesn't mature until age 21 per research, was inundated with stimulants... I was essentially destined to be a drug addict, conditioned... add in the childhood and adolescent trauma and unfit, neglectful parents... Viola! An addict! I was failed... I didn't have a chance sadly. But I won't be anyone's victim or a statistic.
I understand how you feel, and we just have to fight that much harder... it's awful... it's hard... I feel so alone too... i constantly struggle with "why can't I be happy like everyone else?" "What's wrong with me?" "I don't understand, what am I missing, what does everyone else have that i don't?" but I'm here to say that it's not your fault. Look into childhood PTSD and think you might find the answers you seek there my friend. Keep on keeping on friend.
P.S. "People who don't believe in magic will never find it"... look around you and I promise you will find what you seek if you truly let go and be present and stop judging/expecting/comparing yourself to others... find yourself and love yourself... ask someone else how to... participate in life and stop expecting something out of life; stop waiting for happiness to clock you in the head... it won't, but there is magic everywhere, just not where we expect to find it.
@@kristinlasart5153 beautiful words
"every addiction is unhealthy"
me addicted to not getting addicted
They should do sit-ups where the upper part of the abdomen is worked, with the legs raised and trying to touch the feet with the hands and its variants that work the upper part of the abdomen, they will see improvements quickly. That upper abdominal exercise will take away your depression and anxiety, it will also heal your mind...
how´?
Brilliant video! Thank you!
Quite clear mechanism
Very good work
insightful and easy to understand
fan of your videos man. can you tell me what program you use for the audio?
We use Audacity.
Wonderfully explained👍
Super explanation
Thanks for the upload, it was quite informative.
It seems like dopamine resistance because of the redundancy in the synapsis, similarly as insulin resistance in diabetes.
so helpful, please make more to cover GABA inhibition, glutamate on learning, & cannabinoid inhibition, it would be the best if you could!
Good information
What a great video.
does this also apply to sugar addiction or beverage addiction like coke?
Thanks BUAP to bring me here
In the therapy for cocaine addiction, how does an inhibitor for the dopamine trnasporter works? Is there such a means of dissolving cocaine molecules in the cells? If there is... How does it work?
Thannks for helping me for my Scouts zoom talk about drugs for the next day.
Please make detailed video to quit drug addiction like antidepressant to help those who are suffering every second
@Eric which supplement ?
@Eric what's shrooms ?
@Eric i am from india and i don't think I'll find any fungi therapist here but ill search more about it if it can help you to quit antidepressants
This video is a life-saver
Awesome video. This video will be a perfect to use to explain drug addiction for my school project.
Excellent
Ive been clean for a month and a half... Ive been a meth user for years. I really lost almost all. Of the pleasurable feelings... Like eating, i can taste the food but the pleasure of eating food is not there so i eat less. Im Praying that everyrhing will be back to normal soon.
Thanks for this very interesting video
Excellent explain ، thanks a lot
Very helpful. Thank you.
awesome clarification
Only give a little bit
Take it all, take it all
Only give a little bit
Take it all, take it all
Only give a little bit
Take it all, take it
Thanks for sharing🥰🥰🥰
You are so welcome
Oversimplification of an extremely complex mechanism
Brian Griffin
Brian Griffin yes it is because dopamine is definitely not the same thing as endorphin or serotonin. So there you go, just with those three neurotransmitters you already contradict yourself.
I don't have all day dude, this was as much as I needed to know.
J
B.C. Griffin
True. Good very simple explanation that is useful to whom? Why?
Very beautiful sweet video ❤
What about doing drugs in the last moments of life. An old person who is about to die can feel that pleasure before death. It won't matter what effects the drug would have, the person is already dying. Couldn't it help them die happier?
Yes that’s fine. One of the best reasons to use drugs. He’s talking more about people abusing drugs when they didn’t need it to get high.
Thats best used of opioids, it makes you not care about dying
Good one! Educational!
Thanks
If you use drugs and the reward system desensitizes, but if you stop doing drugs will the reward system be permanently desensitized or can it be like normal again?
Excellent explantion
Very easy video
I’m guessing Masturbation has the same application here too.
Thank you very much
Uzależnienia
Na forum było pytanie o uzależnienie. Wszelkie uzależnienia można zastąpić troską o system, czyli pomocą dla zwierząt i roślin, przy których występują niezwykłe doznania, uczucia i euforia, które z niczym nie można porównać. Ludzi, którzy w systemie czynią destrukcje, uświadamiać, aby w trosce o system pomagali zwierzętom i roślinom. I w systemie negatywnymi myślami, słowami i uczynkami, nie czynili destrukcji, za którą na pewno poniesie się konsekwencje.
great piece of information.
Can you do a video on meth overdoses that cause death IM curious about the number of deaths by overdose
Very helpful thankyou
fabulous video
I think my brother has a drug problem. He acts so weird now.
Good
Same thing for cell phone addiction! Social media addiction 🤮🤮
Right.
I cant leave my phone I can’t believe how much I need it I sleep with it beside me !! Ahhhhhh
I started fearing smoking weed when I saw my neighbour's son dancing to the sound of my generator (in nigeria) when I switched it off he asked me who sang that song because I was afraid he would beat me, I answered "Yamaha feat. Petrol"
JUSTICE.
NOW.
Thanks sir this is helpful
Well. At least they're not trying to claim addiction is a DISEASE.
Sir if the caption blocking the video how people will benefit from your video ???