The Quest to Slow, Stop and Even Reverse Aging | Future You | NPR
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- Опубліковано 24 вер 2019
- Scientists are better understanding why we age - and they're also better explaining the cellular changes that lead our bodies and brains to decline.
This research has led people like David Sinclair, a geneticist at Harvard Medical School, and Peter Attia, a longevity doctor and oncologist, to challenge the conventional wisdom that aging is inevitable.
Sinclair believes the humans of the future will live decades longer than we do now, thanks to biological and technological interventions that are already being discovered.
In short: Better understanding the mechanisms of aging has led to promising treatments to slow, stop and even reverse the symptoms of growing old. And turning back the clock this way isn't just about more lifespan; it's about extending healthy, vital years. Could pills that mimic the positive benefits of exercise, at least in mice, be effective for humans? And what does this portend for the future, if we will all live decades longer?
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We need more people investing in this not in apps
although...were it an app we could get more people to invest. *enter sound of thickening plot here
Yes instead of creating disruptive apps for our devices we should focus on advancing biological sciences.
Well said!
Elon musk is putting loads of money into this
It makes me feel better that when i get older (as i am 15) that i could live longer and pr long my life and keep doing this until i can be "imortal"
@@joshcopeman8298 as a 13 year old I will hopefully live atleast 300 years longer than my parents
"He’s an aging professor at the University of Illinois" sounds very different from what was intended 😂
3:05 - I would really like to see an actual visual age reversal in mice. Like two pictures, how mouse looked when it was old and how (young) it looks now, after treatment.
Great report, loved the fact that you included footnotes and acknowledged that this kind of fountain of youth topic is terribly liable to get hyped by those who desire to live longer and those who, recognizing a promising market, sell substances to serve ppl's hopes and dreams. Apropos, the footnotes pro's admonition that this field nonetheless deserves our enthusiastic interest was also most welcome. Thank you again! Deserves waaaay more views, omg.
I loved everything about this report. Thanks NPR.
Just want to point out that regardless of this, the death rate is still hovering around 100%.
Gator Rican,
Good for you.
When new therapies come out, you can say no thanks!
I so love the light-hearted, but still scientific, way of this feature. Often, controversial research fields like aging are presented too "seriously" always with dramatic tones in sound effects and narration. Science journalists learn from this take! Science is self-correcting because of the rigorous nature of selection and competition in science publishing. We should be highlighting more of the published works in top or prestigious journals with many footnotes as so done here.
Thanks NPR and Elise. Very informative video.
Thank you NPR for covering this! Wow!
I have been watching Dr. Sinclair's interview and this is the best so far. Very informative conversation. His book is also very educative. I love that book. In there, there's no point increasing lifespan without health span. The goal should be to live longer while staying young and healthy. Sinclair believes that in the foreseeable future, it's possible for humans to live beyond 120 or even 150, without the frailty, diseases and disability we now associate with old age. I hate aging and the illnesses it brings over time. This is why I am now taking NMN supplement by Vitruvin constantly.
I love Dr. Sinclair too! I owe him the experience I am enjoying now just by taking NMN. I've seen many popluar NMN brands in the market but only few are proven effective. My parents switched to Vitruvin as well after figuring out that I had the most effective results more than the brand they're using...
Please provide link for purchase.
I bought Dr. Sinclair's book "Why We Age and Why We Don't Have To." It's so educative and phenomenal. Through him, I learned about NMN supplement particularly by Vitruvin Health 500mg, it's been a couple of months now as also recommended by a close friend. All I can say is that it’s cost-effective, overwhelming energy is felt, and promotes your overall health...I am looking forward to feel and see the same result in the following years… 😇
Thank you for the video! I liked that you included your results! It’s great! 👏🏻👏🏻
Hope Dr. David Sinclair followed by his team of scientist can succeeding in reversing aging as fast as they can. The good reasons in eliminating this dangerous disease is because think about our grand parents passing away due to their biological aging not only it destroys our health and well-being assets therefore it also made their grown up or adult children cannot have a both happy and exciting life seeing their parents encountering this unwanted scenario. Likewise, why cannot for example all of the family members each not retire and working together to fight their way for a beautiful and happy life with permanence!?
Divorce rates are going to sky rocket 😂. I can already see it. Marriage contract will need to be changed. Hopefully we can reverse aging youth is an amazing thing that ends so quickly.
So what was the NMN supplement that Dr. Attia suggested you use?
Hey John! A lot of folks are asking, so here is Dr Attia's full, technical write-up on all the NAD boosters and other tactics available. We featured NMN but there is also NR: podcastnotes.org/2019/09/09/attia-9/
Well you still don’t tell us the supplement you took! There’s just a general link to nmn products on amazon the majority of which is simply crap. Dr. Sinclair said he’s not taking sublingual supplement so what was the molecule? Why aren’t you guys being honest?
@@EliseHu But it doesn't tell us which one is the good one (since he says most are crap and not legit).
pretty sure it's Alive By Nature
Genex Formulas dot com; they work with him directly; been taking it for 2 years now. Love it. Been on the NAD/PQQ program since 2016, now on NMN, resveratrol and berberine from the same company.
i love her interview, seems happy interested and connected
Why are you kissing her ass?
I think she looks younger after.. this just motivates me to work out!!
Where do I find the Footnotes mention at 5:50?
Great interview by this energetic lady
Why are you kissing her ass?
I’d love to contribute to this 😮💨
I don’t know why but I like this lady. 😄
Which brand of nmn does Attia recommend?
To all those who don't want to live longer and to those who just don't understand the science, THANK YOU! Your sacrifice to allow others to live longer without your presence is inspiring and I hope other like minded folks follow your "heroic" example.
How long did she do it for?
If it happens, I think people will really have a lot less children. It's likely going to be used on the eldest people who opted to have their age reversed. It then can take those people out of retirement and back into work. it could reduce the amount of pensioners while also increasing productivity simultaneously.
If one day we get to live much longer and healthier the smarter ones wouldn't rush to have children, but others who don't even practice safe sex now would, and wouldn't that result in lower overall iq?
@@TheHorrorsPersistButSoDoI The lower IQ also would have less job prospects overall. Less resources by which to afford to have kids. It would balance off.
@@ankelaostheweird905 bold of you to assume the low IQ to care about that
@@kingdomofbird8174 A rat doesn't care, it feels. If it can't eat as well as the dog, it either stays where it is by choice or not, or it finds a way to eat as the dog does.
In short. Those with more, make others desires to follow their example. Smart or not.
Any chance we can use this video with subtitles?
Which brand nmn supplement dr attia suggested?
Please someone tell me
Key points be a little hungry and exercise.
Given the packaging it looks like "Alive by Nature" brand.
To me it looked like Thorne, with label removed
@@glacialimpala Nah, it's alive by nature sublingual tablets 100%
9:20 I'm still older than my calendar age, but at least this process is over and I'm gonna go eat some glucose.
(facepalm)
Needs some METFORMIN in her life!!!
too cool ty
I'm 51, as David, Sinclair, I don't have any supplements and look like him. I follow a keto diet, mostly animal based.
Hi, how long did you do the age reversal experiment before your second blood test, thanks.
6 weeks
The foods highest in NMN are:
Broccoli
Cabbage
Cucumber
Avocado
Edemame
So which NMN did he suggest to take?
how much iu test are u talking grand paa
So what NAD supplement brand name was used / recommended to be more trustworthy? An amazon link please
They are lying and this is more like An infomercial. Shame on NPR .I can think of 5 other studies like this that tout a different molecule to do the same. You really want to look younger and age slowly than look at this No Bullshit needed just Honesty. ua-cam.com/video/tDVBUUfsP8k/v-deo.html
@@Gcanno Gardening?
Then farmers would be immortal...
@@Gcanno lol
The Mouse with the biological cells lasted a few months longer than the old one. You can be young but you're time will come. At least pass away young.
I’m freezing my cells it’s like why not just in case i need them to reverse ageing
NMN or NR? 🤔
She looks younger too at the end
Get rid of the heat of the body, and reverse aging
Feel like if we figure out how to stop aging real estate will go up!
How do they accelerate the age of the mice. I cant find that information.
They have done this in many clínical studies. Stress has been shown to biggest factor in aging
@@bottseo I am asking specifically about the mice in this study
If we didn't react the way mice do to therapeutics mice wouldn't be used in labs around the world that test them and a host of other things.
Overpopulation is not going to be a problem. Birthrates are declining.
Well, eventually overpopulation will be a problem (If no one ages), but not for a very long time. The main issue would be overcrowding in major metropolitan areas, because the infrastructure wouldn't be in place to sustain everyone.
@@peterlewis2178 We will be colonizing space by then.
@@amperro Yeah, precisely. Actual overpopulation may very well never be an issue.
@@peterlewis2178 well humans will definetly start colonizing space atleast by 2030-2050
Look for Unity Biotechnology company
Why is 24 considered optimal?
I might just be drunk, but all them leafs that the lady is standing behind look like pot leafs lmao
Believe you me, we can already do this stuff
It's just a matter of when they decide to release it
Or if they decide to
I don't understand how if we can age backwards then how is eternal life not possible? That would only be the case if we don't entirely age backwards. Personally I switch between wanting to live for ever and wanting to die so I don't know what I want
Ok so who's drinking the water 💧!
🥂 water is life !
Aging is cells playing telephone
It appears that it’s universal for information to change overtime from the original
Somehow I look more younger when I’m overweight.
Your facial fat plunks out your wrinkles. Buy you're aging a lot internally.
@𝒦𝒽𝒾 𝒲ℴ𝓇𝓁𝒹 ☥
The facial fat plumps out the wrinkles making people over 40 look younger.
But obesity makes people under 40 years of age look 40.
You didn’t tell us which NMN supplement was the good one tho. ☹️
If you slow down video you can see that it's alive by nature sublingual tablets. If you check it out on their website you can see labels on sides and it matches the one in the video
Iam happy the time and the place i was born for multiple reasons iam happy to be in USA for the science advance the technology everything that’s happening Iam happy
Don't be too happy this tech might not ever come out in our lifetimes.
Nad+ hasn't been fully tested in humans which is extremely expensive,
But it has been tested across species and
Mice are mammals....we are mammals
So she took the Nad and altered diet. If it works we wouldn't know which caused positive effect . Great
FDA now banned NMN
lets make the worlD young !!!!
As a side effect of cancer treatments I am going through reverse aging. I was bald and gray and wrinkled, now my hair is dark and thick and I have a full head of hair. My skin is smooth now. My pulse and BP are perfect, as are my numbers for everything, like an 18 year old athlete. I just have stage 4 cancer. No one is interested in anything that is real, only what is nonsense.
What was the anti vancer treatment you have been taking?
Jdlc surgery, radiation and chemo. But more important than that even is the issue of imaging, finding the cancer to zap, rather than just zapping where you think and hope it is. In my case a PMSA PET scan found a couple of hotspots in unexpected places which we zapped hard along with the the usual areas. It looks like that did the trick. To deal with side effects of radiation I use lots of CBD infused into coconut oil, both seem to work well. I stayed sane through the 2 year adventure by drinking kava. My latest results last week showed no signs of any of my cancers. It can always come back but it looks pretty good. I’m still stage IV but Stage IVa, which means I can live a lot longer maybe. I’m BRCA2. For the metastatic prostate cancer I am on the Stampede protocol, radiation plus zytiga (abiraterone acetate) plus prednisone. I take that chemo every day, for the past year and for the next two or three, possibly forever. Costs $10k/month tho. My insurance covers the generic, which only became available a month before I started it. J&J lost their court battle. Otherwise I would be dead. The 12 month survival rate for this cancer is 5%. I have had it for two years. Got lucky.
Last time i checked many cancers were a function of aging, as are many diseases.
Once you get one chronic disease others tend to follow.
Metformin is for diabetes, but some use it off label for aging.
Research has shown many people taking Metformin for diabetes also seem to be protected from some cancers.
NONSENSE?
I don't understand why some people protect aging so much when it is the cause of so many diseases. Is aging your friend? I really will never understand some people.
@@krnewman rip
I am still alive and thriving. NED. The new protocols for mCRPC are remarkably effective.
Oh god, why'd I read the comments of so many cynics? If you felt inspired by the video above, do NOT read that lays below.
It might help to realize that a majority of people are not mentally equipped to deal with the past, present, or future. Don't let that hold you back from exploring important information.
People are cynical because there is no Magic Pill. Although living Substantially longer is possible through discipline and Care .There are Important issues these people don't mention Like Gene's, Environment, access to nutritious food, Discipline to carry out Fasting, managing stress,Wear on the body through lifestyle or work,And the Fact that each and everybody is made of Trillions of Microbial cells that outnumber Human Cells 10-1 yes sounds crazy but it's TRUE and people's Biomes react different. To think pills or magic potions are going to come and interact with all these variables to make you live longer, now that is crazy . People are already living longer there are always outliers Who can be learned from And these researchers would be the last people I would Be taking any advice from.
Right now there is nothing to make you retain your young age, nothing on the massive scale. Hence why its a "quest" I.E. the work isn't done yet. Nobody sensible here is believing reverse aging videos is available right now.
Its not about stopping the ageing process .... it's about stopping ...sickness ... disease ... ageing and dieing ! ... check out Facebook group ... IMMORTALITY ... the mechanical way ...
More like both actually.
Why not separate groups of rats and try these? One group bathe every day, another one eats sugary food, etc to see which lives longer and how it affects their hair.
I listen to Eminem, it has stopped my brain aging in its tracks!
HA!
me2!
Sign me up for an exercise pill when they are fda approved. Hopefully before I'm 80
Pet the kitty😻
Lol. I can help you now.
Which molecule do they give the mice to make them look older?
No molecule. If I'm correct, they'd put them through radiation blasts which would break up their DNA, promoting cellular senescence, and aging as a result
Nmn
More npr more
reverse aging？ wow, don't turn me back to a baby.
i love your energy, that made you beautiful.
If reverse aging is possible I am gonna attend American highschool as a jock
It most likely is possible as far as reported.
This was more of a sales pitch than an article. It seems that it's meant to boost the sales of NMN manufacturers. In essence, this is a testimonial ad that is thin on facts. You briefly touched on what steps you took to lower your age by 5 years. Can you expand on or provide an actual log and the details of what you did? I don't think you even mention a timeframe. What regiment did you follow? How much sleep did you get daily? How did you change your routine? What restricted diet did you follow? How come you couldn't eat before noon? How frequently did you exercise and what was your actual exercise? It seems you glossed over these facts, provided very little information, and pitched the dietary supplement.
if it was true she would show brand of NMN so no its just simple video for simple people
I am more concerned with the test. What is the internal age test looking at? How is it deriving at the answer? What is the age based on, the adverage population? Was there a study completed? The test seems unscientific. If the test asked you lifestyle questions and you stated you were exercising more and so forth...would the test give you a better age score.....she said it was blood based but no other info was given...
@@dc9631 That part is legit, they take your blood glucose trend, measure inflammation, oxidative stress, blood lipids and immune cells etc. You can do it on your own if you're not from USA (where I'm from such blood panel is under 300eur)
We must consider aging as a disease..😠
Hmmmmmmmmmmm sounds more like disease/ alignment manipulation. Essentially deleting or reconverting dna to serve a purpose. My only question is how long does the modification last and if begins to breakdown will breakdown at a higher rate.
Is it just me or is there a lisp when she speaks?
Lol, like plastic surgery, can you stop the internal clock?
Leave mice alone
Or consume 30% less calories
I never quite got how it works in practice. If I eat 30% less than BMR x activity coefficient, I will lose weight slowly and so my BMR further drops. What prevents anorexia?
I really thought she was in her 40’s.
She can pass for a 45 year old Mom.
2050-2059
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2050
• Humanity is at a crossroads
• Nearly half of the Amazon rainforest has been deforested
• Wildfires have tripled in some regions
• Traditional wine industries have been severely altered by climate change
• Fish body size has declined by nearly a quarter
• Hi-tech, intelligent buildings are revolutionising the urban landscape
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• China completes the largest water diversion project in history
2051
• The U.S. population reaches 400 million
• An interstellar radio message arrives at Gliese 777
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2052
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2053
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2054
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2055
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• Global population is reaching a plateau
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2056
• Global average temperatures have risen by 3°C
2057
• Handheld MRI scanners
2058
• A billion human brains can be simulated in real time
• The Beatles' music catalogue enters the public domain
• A radio telescope is built on the Moon
2059
• The end of the oil age
• Mars has a permanent human presence by now
2060-2069 »
INDIA already have thousands of books written on it from past more than 5000 years it's by YOGA. Please visit India and meet yoga expert.
Looooooooooooooool
No thanks
@@cwstars yoga is for braindead zombies
Hiii 😊🥰👌😋😋😋👌👍
Terrifying! Lol
IKR!!! Imagine not getting Alzheimer's, Arthritis, Heart Disease, Cancer etc.
BUT THE GREAT NEWS IS YOU HAVE THE RIGHT TO SAY NO TO NEW TECHNOLOGIES!!!. You will be able to feel all the pain that comes with these diseases!
Many even many years in bed with bed sores. Cool!
why scientists did not do himself.. he is still old, do you think I believe this No!
I want to find out if the kitty got better
Only ten years more by 2050?
This Jay Oshansky - your NPR " Footnote" aging guy looks like he's 100 yrs old
So, whatever he's knows is ...
Animal cruelty! 😢
Why worry about getting younger when u hit the wall as a woman 🤷. It won't increase chance for a better guy/husband and more babies so it's a waste of time really....but u can work a job longer single...
r u suggesting a nuclear holocaust ?
Trust me, folks: it doesn't work in humans. I swear it's true. Haha
Agree, i hope they just kidnapped human to use it as experiment object
When she was NPR' s Asian correspondent she covered garbage news ( celebrities and other meaningless useless knowledge) which also translates into her new role. She's also a member of CFR ( Council on Foreign Relations) which points to her as careerist and useless generalist. For people who find this pseudo-science informative ,the only people they are fooling are themselves.
Tf, she has nothing to do with the research
This old lady is lost. she thinks meditation means putting on headphone and listening to some tiben singing bowl!!! Western population has no clue what meditation means or how to do it.
Meditation is to be "hear and now". Meaning don't put anything in your ear and just close your eyes and listen to everything coming in and ignore. don't hold onto any of the thoughts or external noise. the point is to bring you to the current(hear and now) moment, because you're constantly either thinking about future or in past and rarely IN THE MOMENT. That's where meditation comes in.
So she's going back to the bad diet?
Mko ye dawa de do...mko kisi ko dena hai...😭😭😭😭
dont make babies lets be came gods
Animal cruelty! 😢