Always Express Meibomian Glands after Intense Pulse Light IPL Toyos Protocol = FDA Protocol

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  • Опубліковано 3 бер 2024
  • There has been some controversy about the value of expressing the meibomian glands after IPL treatment. And for that matter, expressing the glands after any treatment, such as Lipiflow or IPL, that heats up the glands enough to cause liquefaction of abnormal meibum secretions.
    I have heard various ideas on handling MGD with expression. The ideas are getting further from the true physics of MGD.
    The anatomy of the meibomian gland is a tube containing a fluid with a certain viscosity. Water has low viscosity, and honey has a higher viscosity. These are considered Newtonian fluids because they follow the basic principle that the viscosity at a given temperature would remain constant. But we know that abnormal meibum is more like toothpaste, therefore non-Newtonian. That is why the normal stress of blinking does not cause enough stress to release this abnormal meibum. This toothpaste-type meibum needs heat to lower the viscosity.
    With non-Newtonian fluids, as you apply pressure, the viscosity will decrease with shear stress. When we express the meibomian glands, we take advantage of the non-Newtonian properties of abnormal meibum. Our FDA study on IPL demonstrated even eyes that were in the control group and just experienced expression without IPL felt some symptomatic relief.
    What is the best way to express the gland? Newtonian physics tells us that fluid will go from an area of high pressure to low pressure. The meibomian gland is a tube with outpouchings, so when you squeeze from the center, some of the abnormal meibum will come up through the opening, but some will go down into the outpouchings. If you use a mechanical expressor, you will always be squeezing on some portion of the tube - middle, upper middle, lower middle but never from the very bottom leading to incomplete expression. If you squeeze again at the same plane every time, as does pulsation system in Lipiflow, you will not get any more meibum because you are not squeezing from the bottom of the gland. In non-Newtonian fluid, shear stress over time will lower the viscosity of the toothpaste, and the same for abnormal meibum. The best way to express is from the bottom with constant force over time to lower viscosity.
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