What are Prions?

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  • Опубліковано 1 жов 2024
  • Be sure to watch the video on proteins to better understand the following video on prions. Learn about prions, how they interfere with the body's proteins, and how these indestructible proteins can cause disease and death in humans. TSEs such as Mad Cow Disease, Kuru, and genetic abnormalities are also explored.
    Music: www.newgrounds....
    Maria Sahines made the animation. :)

КОМЕНТАРІ • 198

  • @mandybeattie8134
    @mandybeattie8134 3 роки тому +122

    I came to this video because I heard about prions on tik tok and I wanted to know more. I had no idea mad cow was a prion disease. My grandfather died of Creutzfeldt-Jakob Disease (Mad Cow), and the doctors had no idea where it came from. They were worried it may be genetic. His mental state deteriorated so quickly; he started forgetting our names and becoming delusional, then he lost all motor skills and speech. April, he was totally fine, then by September he was gone. Craziest part was when he was asleep, it was like he wasn’t truly asleep. During the day he could hardly move but when he was asleep, his body was moving constantly and he would do everyday motions of things like counting coin, driving a car, eating or drinking, flipping pages of a book- all while asleep in his bed. It seemed as though he was never able to rest. I’ll never forget that summer of 2011, spending days at his bedside as he muttered unintelligible things and had a truly vacant expression behind his eyes. The last time I ever saw him (days before he passed), he mustered the clarity to wave his index finger at me. Such a sad and strange disease.

    • @missdarkhumour2222
      @missdarkhumour2222 3 роки тому +17

      I’m so sorry to hear that. I got chills when reading his disease process and how he presented.

    • @apostolicsolidarity
      @apostolicsolidarity 3 роки тому +6

      Mad Cow and Creutzfeldt-Jakob are two similar but different things. Practically the same thing but one affects Bovine and the other affects humans

    • @mihiranrao
      @mihiranrao 2 роки тому +7

      there is a great book about prions if you want to learn more about it. my teacher recommended it to me a couple months ago, its called "the family that couldn't sleep." it covers all the kinds of prions in the video.

    • @Faridgh
      @Faridgh 2 роки тому +5

      I hope your grandfather rests in peace

    • @jeffjones3040
      @jeffjones3040 Рік тому

      Was there a period of the disease where he smiled most of the time? the Kuru version (if there is any difference at all from Creutzfeldt-Jakob) is known to have that bizarre and horrifying symptom.

  • @fables4564
    @fables4564 3 роки тому +65

    Researchers for this disease are like... “If I die, I die.”

  • @FrappuccinoAlfredo
    @FrappuccinoAlfredo 3 роки тому +65

    Never thought anything was scarier than cancer

    • @sneezewatch
      @sneezewatch Рік тому +19

      Dementia is 100% scarier than cancer. Imagine if everyone you loved, everything you owned, and everything you know started to disappear from your memory. THAT is my greatest fear.

    • @protipskiptoendofvideoandr286
      @protipskiptoendofvideoandr286 Рік тому

      @@sneezewatch after a while you wouldn't even know so ot all works out

    • @gothelvis3541
      @gothelvis3541 Рік тому +2

      Rabies, Prions, Lyme Ticks and Mosquitoes

    • @Flowshow88
      @Flowshow88 2 місяці тому +1

      You havnt seen my ex girlfriend

  • @2233golf2
    @2233golf2 7 років тому +51

    Due to lack of brain this cant happen to me....... (my dog wrote this for me...)

  • @typingcat
    @typingcat 5 років тому +22

    1 in 1M is still quite high. That means that about 7,000 people worldwide or 300 Americans getting this horrible disease each year.

  • @thelostsoul1531
    @thelostsoul1531 9 років тому +37

    dont worry chris i didn't want to sleep tonight anyway XD

  • @Reallytallsocks
    @Reallytallsocks 8 років тому +62

    I guess if I die then I die.

    • @whosyourdaddy4579
      @whosyourdaddy4579 7 років тому +2

      Sweetheart...it's what happens to you BEFORE you die...don't you get that?

    • @Snazzy12341
      @Snazzy12341 6 років тому +11

      People die when they are killed

  • @lolliker1875
    @lolliker1875 3 роки тому +14

    I really like the way you explained about prions, its simple and yet you gave enough information to really understand what they really are.

  • @BreezyInterwebs
    @BreezyInterwebs 9 років тому +77

    Hm. I always pronounced it as "pry-on" not "pre-on." Glad to know how it's actually pronounced now.

    • @Elephantdude
      @Elephantdude 9 років тому +6

      No no nooooo its pronounced pry on

    • @rolan638
      @rolan638 9 років тому +2

      Its pronounced praeiy-oun :)

    • @cyn7261
      @cyn7261 9 років тому

      +TG CoffeePlus What are you doing on Super Scienced? :P

    • @BreezyInterwebs
      @BreezyInterwebs 9 років тому

      Geometry Dash SyntheticS because I like Chris? ( ͡° ͜ʖ ͡°)

    • @wheelchairgaming1702
      @wheelchairgaming1702 6 років тому

      Me to

  • @tufaznail
    @tufaznail Рік тому +2

    Do the covid shots do this?

  • @不幸屋の娘-o6l
    @不幸屋の娘-o6l 6 місяців тому +1

    This video aged really well. Now CJD is super common because of the 💉💉💉.

  • @apamber4491
    @apamber4491 3 роки тому +4

    Very informative
    Thanks brother!

  • @prestonhinckley241
    @prestonhinckley241 2 роки тому +5

    Can a prion be transmissed from one species to another through mosquitoes?

    • @K.Pershing
      @K.Pershing 2 роки тому

      No its caused by protein missfold it is not a bacteria or virus

    • @tsachinovique4233
      @tsachinovique4233 2 роки тому +5

      Now you thinking 🤔👍🏼

    • @michaelcandido2824
      @michaelcandido2824 Рік тому

      Yes on the first question and not sure on the last. I’d be worried about Covid and infected bats.

    • @ChinchillaisGod
      @ChinchillaisGod Рік тому +2

      Late comment here, but BSE (mad cow disease) has never been found in milk, blood or meat. So no, a mosquito would not be able to transmit prions.

  • @BlissBee
    @BlissBee Рік тому +1

    i remember 7 years ago found this video because yknow i was a young 10 year old little lad who enjoyed sjb videos came across this and ever since then whenever i would have a sleepless night and still struggle sleeping later on in the day i would get paranoid that myabe just maybe a 0.0000001% chance it might be FFI i didnt even know it was called that until about half a year ago btw and yeah i dont get paranoid about it anymore because learning its name also made me realize im stupid and the only people who suffer and die from it had family members who previously died from it too
    idk prion diseases are probably the most horrific diseases to ever exist

  • @jasonulriksen8897
    @jasonulriksen8897 Рік тому +1

    1/1,000,000 is not rare enough to confort me

  • @guatemalantomcat
    @guatemalantomcat Рік тому +1

    Insomniacs at 2:00 : 😀

  • @shalzification
    @shalzification 9 років тому +3

    45 mins and I'm 8th XD Love the vids, the only channel which I watch ALL the vids as soon as I see them, cuz they are so short and not overloaded (coming out everyday)

  • @multistanline9193
    @multistanline9193 Рік тому +1

    Thank you so much.
    This video is a vey very big help

  • @ds4933
    @ds4933 3 роки тому +108

    POV: you’re here from the TikTok girl

  • @sarahstellar1433
    @sarahstellar1433 5 років тому +2

    this has the potential to create "zombies" lol

  • @thelunaticcultist5157
    @thelunaticcultist5157 6 років тому +3

    Ayyyyyyyyyy! It’s superjombombo!

  • @mohammedalshames7337
    @mohammedalshames7337 Рік тому +1

    Whatever podcast? Anyone?!

  • @Zanodia
    @Zanodia 3 роки тому +1

    I do not understand how a protein can cause so much trouble just by being misfolded, nor do I understand how they break other proteins. They also don't denature? What about bombarding them with electrons?

  • @obnoxiouscat6269
    @obnoxiouscat6269 3 роки тому +1

    pov: ur here because of invincible ep 5 end credits

  • @TheRealKingOfTheUniverse
    @TheRealKingOfTheUniverse 7 років тому +2

    heat
    say that one more time
    heat don't stop prions
    well you know no element human have discovered can not melt on the coldest part of the sun

  • @ashdos7205
    @ashdos7205 4 роки тому +3

    His voice i soothing....

  • @mellomilky8621
    @mellomilky8621 8 років тому +3

    Thank you very much for the video!

  • @baroo22787
    @baroo22787 5 років тому +2

    oh boy now im scared

  • @bartholomeusnebuchadnezzar2463
    @bartholomeusnebuchadnezzar2463 4 роки тому +1

    So bassicly zombies.....

  • @El_Presidente_5337
    @El_Presidente_5337 4 роки тому +1

    I'm just here because of Plague Inc

  • @dylankrebs9262
    @dylankrebs9262 6 років тому +2

    The visuals really helped me understand better. Thanks!

  • @Naturenerd1000
    @Naturenerd1000 7 років тому +2

    This is disturbing. A disease that can't be killed through cooking. If this is true how is it so rare, and how is anyone safe from this?

    • @stxnw
      @stxnw 7 років тому +6

      Naturenerd1000 That is because cows are strictly regulated.

    • @bruhmoment1835
      @bruhmoment1835 5 років тому

      Maybe cause it has like an incubation of 50 years or more, and brains aren't that well liked to be eaten.

  • @synthman66
    @synthman66 3 роки тому +2

    Outstanding!!! 👏🏻👏🏻👏🏻

  • @buthter
    @buthter 2 роки тому +1

    💀Bro is a nerd

    • @buthter
      @buthter 2 роки тому +1

      💀facts

    • @buthter
      @buthter 2 роки тому +1

      💀true true

  • @shroqhafed5717
    @shroqhafed5717 3 роки тому +1

    I would like to thank my proteins

  • @jacevans1946
    @jacevans1946 6 років тому +2

    Class video mate keep it up!

  • @Flowshow88
    @Flowshow88 2 місяці тому

    Thank you so much for your time and content ❤

  • @treefrog123a
    @treefrog123a Рік тому

    And turned into biological warfare

  • @iulia5689
    @iulia5689 4 роки тому +4

    Donate to the prion alliance!

  • @gavincurtis
    @gavincurtis 3 роки тому +1

    These will become popular again.

  • @gothelvis3541
    @gothelvis3541 Рік тому

    I've always known about these but for some reason I haven't looked into them until now. I truly regret mt decision

  • @musicmixxer9815
    @musicmixxer9815 9 років тому +2

    Very informative! Awesome :D

  • @tajsingh6574
    @tajsingh6574 3 роки тому +2

    The video said that cows also get it from meat… aren’t they herbivores?

    • @mikoyan454
      @mikoyan454 3 роки тому +4

      Some farmers fed their cows with parts from other cows. @1:40

    • @mignat664
      @mignat664 2 роки тому +1

      @@mikoyan454 wtf

  • @troyshealthtips35
    @troyshealthtips35 2 роки тому

    It's a simple matter of latter ... The patterning language that begets prions is no more than mRna

  • @m1dogs
    @m1dogs 9 років тому +5

    Lol at first I thought it said Prisons...

  • @gingerroberts4383
    @gingerroberts4383 9 років тому

    The numbers are higher. He's also wrong about the ban against feeding cattle back to cattle. They still feed baby cows ,10% cow blood. Next time you want to a video about this deadly disease, go do some real research and read some newer study on it.

  • @JackAtkins-xz5wi
    @JackAtkins-xz5wi 7 місяців тому

    Jesus Christ is in Nunawading

  • @22inominata
    @22inominata 6 років тому +1

    Nice presentation and interesting animation. Thanks!

  • @jeffjones3040
    @jeffjones3040 Рік тому

    So, 2000 degrees for an hour won't kill or destroy it?

  • @Mercenary-1914
    @Mercenary-1914 2 роки тому

    Infographics recent video about eating human flesh brought me here.

  • @dylankrebs9262
    @dylankrebs9262 6 років тому +1

    Oh and by the way. I just subscribed to you. The amount of effort you put into this is just insane.

  • @disposabledishsoap6520
    @disposabledishsoap6520 8 років тому +1

    Greatest channel in all of history!!!!

  • @praveenaparamanandan4614
    @praveenaparamanandan4614 5 років тому +1

    Osm vid...made my NEET prep easy

  • @patriciabarroso1572
    @patriciabarroso1572 4 роки тому

    What is the force moving them ? Where is their soul ? At least viruses have a body like structure, but those ?

  • @diamondminor
    @diamondminor 2 роки тому

    We watched this video in my PathoPharm course and I was like "yo, what is that Chris???"

  • @J.Green-Rx
    @J.Green-Rx Рік тому +1

    There are 7 prion-like domains in the S1 part of the spike protein in the vaccines.
    The abstract from the paper "A Potential Role of the Spike Protein in Neurodegenerative Diseases: A Narrative Review" goes into detail.

  • @sigmamalegrindset132
    @sigmamalegrindset132 3 роки тому

    jesus christ is 2015 6 years ago??

  • @disposabledishsoap6520
    @disposabledishsoap6520 8 років тому

    Question? If your body knows this then how come u dont as in a regular person

  • @juliusjames4460
    @juliusjames4460 5 років тому

    This is what's happening now calling it zombie dear desease

  • @Cristian145
    @Cristian145 9 років тому +1

    FIRST

  • @sealc4465
    @sealc4465 7 років тому

    43 is... wait ain't going to say 43th... GOD DAMIT

  • @Thenormalguy101
    @Thenormalguy101 9 років тому

    i dont know if anybody got here from a book
    "last dog" any body?

  • @ecocaos575
    @ecocaos575 7 років тому +1

    Great job!!

  • @gladystsang5648
    @gladystsang5648 9 років тому

    hii :) I really enjoy watching your video on 'prions' and I need to make one video on a similar topic, would you mind telling me what website you are using? :D thxx!!

  • @Iwillhurtyoureallybad
    @Iwillhurtyoureallybad 6 років тому

    Here because of Joe Rogan

  • @whatisthis2809
    @whatisthis2809 6 років тому

    2:00 Um what? I fall asleep at four am everyday.

  • @matthewdockray9745
    @matthewdockray9745 9 років тому +2

    Best video yet! Really informative and interesting, great job Chris and good job to the animator, both of you are top schnarfs
    ;)

  • @soundapodaca
    @soundapodaca 3 роки тому

    Genetic mutation V127

  • @mndflnslgn2880
    @mndflnslgn2880 3 роки тому +1

    These could also be injected.... 🐑🐑🐑

  • @frankieyoung7399
    @frankieyoung7399 9 років тому +2

    I love you christopherrrr

  • @dhdhensmsm3280
    @dhdhensmsm3280 5 років тому

    I thought rabies is the worst , however those diseases are equally as bad as it .

  • @Alice444V
    @Alice444V Рік тому

    amazing video!!

  • @heisenberg7985
    @heisenberg7985 6 років тому

    with one hundred 100%! hahaha

  • @moneyfunny443
    @moneyfunny443 5 років тому

    #Canivalism hate this vid

  • @katiebailey7872
    @katiebailey7872 2 роки тому

    Urg@

  • @joonhoyoo886
    @joonhoyoo886 9 років тому

    Extream tri same age samething

  • @jango20124
    @jango20124 8 років тому

    Actually you can burn prions, thus destroying the peptide bonds, destroying the prions.

    • @KelliePixieAshton
      @KelliePixieAshton Рік тому +1

      Has to be at least 480 degrees celsius and needs to burn for hours... but sure, that's one way... doesn't help the people with prions in their brains lol

  • @peuteodoro
    @peuteodoro 5 років тому

    blz, mas quem tá aqui pelo Kogos?

  • @disposabledishsoap6520
    @disposabledishsoap6520 8 років тому

    And superjombombo

  • @chromephugboithe3rd481
    @chromephugboithe3rd481 3 роки тому

    Ooof

  • @santiagocampo9830
    @santiagocampo9830 3 роки тому

    Simon

  • @disposabledishsoap6520
    @disposabledishsoap6520 8 років тому

    More more more more more more
    !!!!!!!!

  • @beautambwe6027
    @beautambwe6027 8 років тому

    be kuru

  • @HaveorcArts
    @HaveorcArts 9 років тому

    1:07 My least favourite number IMO :(

  • @adrianx6165
    @adrianx6165 6 років тому

    Whatever lmao

  • @jaret4t
    @jaret4t 3 роки тому +1

    Why are there prions in the M0DERNA patent?

  • @sice9458
    @sice9458 9 років тому

    wow that is scary

  • @p2021-g8h
    @p2021-g8h 3 роки тому

    I just ate beef today , now I’m extremely scared

    • @ammarahmed219
      @ammarahmed219 Рік тому

      You shouldn't be. You are more likely to die from undercooking that steak than the extremely small chance from it having a misfolded protein.

    • @ammarahmed219
      @ammarahmed219 Рік тому

      Honestly the most scariest symptom of the disease is the media portraying it . Right now you should be enjoying your life now and not fear a disease that has a 0.00000000000000000001 % chance of happening in your life time. Hope that helps clear your mind

  • @posterierman
    @posterierman 9 років тому

    SECOND

  • @disposabledishsoap6520
    @disposabledishsoap6520 8 років тому

    #superjombombo2

  • @BD90..
    @BD90.. 6 років тому

    So cannibals get this

    • @550077
      @550077 6 років тому

      Only if you consider steak eating as cannibalism.

    • @thesmokinogre
      @thesmokinogre 6 років тому

      a550077 don’t eat a cannibal cow

  • @NoorNoor-iw1tc
    @NoorNoor-iw1tc 7 років тому

    love this ❤️

  • @matiqueobrownlee7786
    @matiqueobrownlee7786 3 роки тому +1

    Jab?

  • @bobisthebuilder3982
    @bobisthebuilder3982 7 років тому

    Great video 👍🏻! Short sweet and to the point. Also easy for the average person to understand.
    Thank You

  • @3zc86
    @3zc86 9 років тому

    Thanks I was really questioning myself about prions but now I know so thank you super science

  • @ReverBlade19
    @ReverBlade19 9 років тому

    Sounds really important Chris

  • @ClaymorePvP
    @ClaymorePvP 5 років тому +1

    It is "pry on" not "pre on"

  • @MrAltoid
    @MrAltoid 8 років тому +1

    I think Professor Steelmeat did better at explaining prions

    • @MrAltoid
      @MrAltoid 8 років тому +1

      +oh... Not only the greatest professor but the best one at making boring things funny

    • @feynstein1004
      @feynstein1004 6 років тому

      Who?

  • @LPSJellyBeanWorks
    @LPSJellyBeanWorks 7 років тому +1

    Great.. Time to become vegan. Can't take a risk!

  • @tenochtitilian
    @tenochtitilian 8 років тому

    Why are prions so resistant to heat etc?

    • @annpkmg471
      @annpkmg471 7 років тому +4

      They're a lot more stable due to hydrophobic interactions and sometimes hydrogen bonding between several proteins. This also part of the reason why they form in the first place since things always tend to move towards a more thermodynamically stable state.

    • @Thedoctor19000
      @Thedoctor19000 7 років тому

      Maybe we need a compound with the bond with highest binding energy in chemistry -- the bond between carbon and fluoride -- to combat prions.

    • @Wes8761
      @Wes8761 7 років тому

      They can be destroyed by hear because it shatters the chemical bonds