Hey, you are right i should have put supraoptic nucleus...my fault. But paraventricular nucleus can also secrete ADH, I just had the paraventricular in mind :/ Thanks
You are really a beautiful artist! I love it so much and it is so cool that you know so much about the body and that you are super talented that is a great trait. I am studying in University and your videos are helping me so much!
Another great video! Question: You give 2 separate reasons for ADH release:1) Osmoreceptors in the hypothalamus detect increased sodium concentration in the blood; 2) Hypotension (which I guess would be sensed by a baroreceptor). Do osmoreceptors measure both sodium concentration and BP?
Please could you explain the following: How does an increase in [Na+] lead to decreased BP in the example of vasopressin and the hypothalmus BUT in the second example in the adrenal cortex, decreased [Na+] lead to decreased BP...?
I was wondering about that also. 1. Eating salty food leads to high sodium levels in the blood. 2. ADH is released from posteriour pituitary in response to increased blood osmolarity (concentration). 3. Collecting ducts in nephrons reabsorb H2O into the blood, resulting in H2O retention in the blood, and therefore, increased blood volume. 4. High blood volume --> high blood pressure. To counteract high blood pressure, two things can be done: 1) vasodialtion, and 2) decrease blood volume. Next cycle 5. Sodium is filtered and secreted from the blood into the tubules --> high urine concentration. 6. ADH is absent because blood volume and pressure are high. 7. H2O is not reabsorbed into the environment (blood) from the collecting duct. Instead, H2O remains inside the collecting duct with the sodium to be excreted as urine.
You have to think of these as compensatory mechanisms. For the first an increase in sodium/osmolarity would occur with a decrease in plasma blood volume (would also decrease BP), as in dehydration. Now the body will try to compensate and will enact mechanisms to raise BP.
ADH is mainly secreted by supraoptic nucleus of hypothalamus paraventricular nucleus secrete it in small quantity moreover low bp is due to low osmolarity and low Na+ concentration in the plasma
Thanks for your video I cant find it now Im studying for my next physiology test worth 33%, I got 9/10 for one part talking about cardiac muscle and skeletal muscle action potentials and what happens at each step. I followed your diagrams and made my own notes. thankyou :D
I don't think there's an error there,you see,in this case,there's a loss of water (volemia) but not Na+ in the blood,that loss of water causes an increase of the concentration of Na+ (hypernatremia) ,so the hypothalamus secretes ADH which will increase the reabsorption of water only,thus regulating the concentration of Na+ (no hypernatremia any more) & increasing the volemia & the blood pressure as well
Basically you have a cup full of salt & a bit of water,& all ADH is trying to do is adding more water to the cup so that it doesn't feel so salty & to increase the volume of water to fill the cup enough
I think the confusion is in the way it was stated "low BP -DUE- to high Na" when the golden rule says "H2O follows Na". Indistinctly of High Osmolarity or Low Blood Pressure the body will assume there has been a loss of water volume (why my Na is high?? oh maybe my volume is low) and will activate multiple pathways to reach homeostasis by the release of ADH (when osmoreceptors detect pressure is high) or Renin-AngiostensinII-Aldosterone (when baroceptors detect low BP)
the macula densa with granular cels of the justaglomerular aparatus works as a hormonal control site for Renin-angiotensin-aldosteron when detects fall of ionic (na k cl) concentration in the TF of the distal ascending tubule. By this, exerts a control of GFR that falls, increasing de absorption of tha Na in the proximal tubule.
Old video but i have a question i would love the answer to. Normal resting bp is around 130/80. When you exercise the systolic can reach as high as 220 in a healthy individual. Then why are we concerned specifically about high resting blood pressure?
Murphy's Law! I have been started watch Endocrine system, but I stoped right on this video, and next day I had exam from Morphology and Fyziology, and faaak I took a tikcet with this system, of course I did not know about this well. I was so angry, If I would saw this video, I would passed it, ohh:/ (But, Armando Thank you very much!)
May I ask why at 1:30 the blood pressure will decrease when the osmolarity increases, doesn't more sodium ion retains more water which increases blood pressure?
If there's too much sodium in the blood then it will be removed by the kidneys and water follows the sodium (osmotic pressure), causing blood pressure to drop. Without ADH (vasopressin), this water will be lost as urine.
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Hey,
you are right i should have put supraoptic nucleus...my fault. But paraventricular nucleus can also secrete ADH, I just had the paraventricular in mind :/
Thanks
This guy has no idea how much he's helping me pass medschool 😭❤️
Excellent as usual, you could add a few steps explaining the role of ACTH from the anterior pituitary just for completeness.
Please correct- Anti Diuretic hormone is secreted by Supraoptic nucleus and not Paraventricular (If I am not wrong) .
Pallavi Chaudhary yes you’re right, I just checked my textbook.
anti diuretic hormone is secreted by both of them - ncl.paraventricularis and also ncl. supraopticus :)
REGULATIONS OF HIGH BLOOD PRESSURE ❤❤❤❤❤❤❤❤❤❤
you are awesome dude! you explained it way better than my teacher. Now I gotta watch this video a couple mere times to get it in my head.
You are really a beautiful artist! I love it so much and it is so cool that you know so much about the body and that you are super talented that is a great trait. I am studying in University and your videos are helping me so much!
Another great video! Question: You give 2 separate reasons for ADH release:1) Osmoreceptors in the hypothalamus detect increased sodium concentration in the blood; 2) Hypotension (which I guess would be sensed by a baroreceptor). Do osmoreceptors measure both sodium concentration and BP?
Please could you explain the following:
How does an increase in [Na+] lead to decreased BP in the example of vasopressin and the hypothalmus BUT in the second example in the adrenal cortex, decreased [Na+] lead to decreased BP...?
I was wondering about that also.
1. Eating salty food leads to high sodium levels in the blood.
2. ADH is released from posteriour pituitary in response to increased blood osmolarity (concentration).
3. Collecting ducts in nephrons reabsorb H2O into the blood, resulting in H2O retention in the blood, and therefore, increased blood volume.
4. High blood volume --> high blood pressure. To counteract high blood pressure, two things can be done: 1) vasodialtion, and 2) decrease blood volume. Next cycle
5. Sodium is filtered and secreted from the blood into the tubules --> high urine concentration.
6. ADH is absent because blood volume and pressure are high.
7. H2O is not reabsorbed into the environment (blood) from the collecting duct. Instead, H2O remains inside the collecting duct with the sodium to be excreted as urine.
I believe that in the second example, the increased amount of Potassium in the blood has to do with the decreased bp
Also, If you do not drink enough water, the concentration of chemicals in your blood (serum osmolality) increases hence the low BP.
You have to think of these as compensatory mechanisms. For the first an increase in sodium/osmolarity would occur with a decrease in plasma blood volume (would also decrease BP), as in dehydration. Now the body will try to compensate and will enact mechanisms to raise BP.
Wow. A lot of content in this one. Might have to rewatch at half speed 😂😂
ADH is mainly secreted by supraoptic nucleus of hypothalamus paraventricular nucleus secrete it in small quantity moreover low bp is due to low osmolarity and low Na+ concentration in the plasma
Thanks for your video I cant find it now Im studying for my next physiology test worth 33%, I got 9/10 for one part talking about cardiac muscle and skeletal muscle action potentials and what happens at each step. I followed your diagrams and made my own notes. thankyou :D
1:24
decrease Bp due to decrease osmolarity not increase ( correct it) :) thanks very useful vedio
I don't think there's an error there,you see,in this case,there's a loss of water (volemia) but not Na+ in the blood,that loss of water causes an increase of the concentration of Na+ (hypernatremia) ,so the hypothalamus secretes ADH which will increase the reabsorption of water only,thus regulating the concentration of Na+ (no hypernatremia any more) & increasing the volemia & the blood pressure as well
Basically you have a cup full of salt & a bit of water,& all ADH is trying to do is adding more water to the cup so that it doesn't feel so salty & to increase the volume of water to fill the cup enough
if there is already increased Na+ already why it will reabsorb Na+ again ?
I think the confusion is in the way it was stated "low BP -DUE- to high Na" when the golden rule says "H2O follows Na". Indistinctly of High Osmolarity or Low Blood Pressure the body will assume there has been a loss of water volume (why my Na is high?? oh maybe my volume is low) and will activate multiple pathways to reach homeostasis by the release of ADH (when osmoreceptors detect pressure is high) or Renin-AngiostensinII-Aldosterone (when baroceptors detect low BP)
Zahraa Ulfat tnx this made me confused three times i chaked my summary😖😖
the macula densa with granular cels of the justaglomerular aparatus works as a hormonal control site for Renin-angiotensin-aldosteron when detects fall of ionic (na k cl) concentration in the TF of the distal ascending tubule. By this, exerts a control of GFR that falls, increasing de absorption of tha Na in the proximal tubule.
beautiful presentation! Thanks
How are you so educational...love your content. Very detailed and informative. Thank you Tons
how does a high plasma osmolarity decrease Blood pressure ? I mean... I thought H2O always follows Na+ =/
Great video , this knowledge is better than having gold
Thank you so much for your videos! you make is so easy to understand
Very nice explanation ❤ thanks
love this video, very helpful and it makes it easier to understand the topics.
Is it possible to print off your illustrations? Found this is the best method of revision for me!
Old video but i have a question i would love the answer to. Normal resting bp is around 130/80. When you exercise the systolic can reach as high as 220 in a healthy individual. Then why are we concerned specifically about high resting blood pressure?
Murphy's Law! I have been started watch Endocrine system, but I stoped right on this video, and next day I had exam from Morphology and Fyziology, and faaak I took a tikcet with this system, of course I did not know about this well. I was so angry, If I would saw this video, I would passed it, ohh:/ (But, Armando Thank you very much!)
really well taken thanks alot you are teaching very well thanks alot
The increase of Na\ increase osmolarity causes high BP ( shown in part 1)
Beautiful explanation :)
how could decrease in sodium or increase in potassium concentration lead to decrease in blood pressure? can someone explain it to me . thank you .
decrease in sodium dcecreases osmolarity, therefore decreases blood plasma vaolume, thereby decreasing bloo dpressure.
May I ask why at 1:30 the blood pressure will decrease when the osmolarity increases, doesn't more sodium ion retains more water which increases blood pressure?
wow, nice work, thx for your effort
Good useful video thanks for sharing
awesome video, loved it
Brilliant as usual x
Sooooo, low sodium and water concentration in the plasma causes high blood pressure?
I still do not get it how is it possible that a decreased BP is due to an increased Na concentration in blood. :(
If there's too much sodium in the blood then it will be removed by the kidneys and water follows the sodium (osmotic pressure), causing blood pressure to drop. Without ADH (vasopressin), this water will be lost as urine.
@@st0nedg0at thank u good explanation....
So actually this means that cutting too much on dietary salt will result in an increase in blood pressure :D
it was just marvellous
incredibly useful
Thank you
too good....thank u
this is an awesome review
so fun to follow you!
GREAT. is there any way to get the drawings?
docs.google.com/file/d/0B8Ss3-wJfHrpYlNzSkxaWDNpaWs/edit
Thank you sooo much
Think you so much
Quality stuff
Pt. 1 "click screen" dosent work to redirect
Nevermind, i see it in sidebar now, >_
Love you!
Thanks your the best ⚘⚘⚘
What would corse the bp to stay low.
Amazing
impressive
Bp and osmo I didn't get it ?
Very informative, but too fast for me :(
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