Breast cancer cells dividing by notamadscientist.com

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  • Опубліковано 13 січ 2008
  • See my BLOG: notamadscientist.com & TEDx at • Precision Medicine Whe... Cell division (mitosis) of many breast cancer cells over 3 days. These cells are in culture and placed under a confocal microscope to visualize the microtubules.This movie was taken by the Marcus Laboratory at the Emory Winship Cancer Institute
  • Наука та технологія

КОМЕНТАРІ • 54

  • @marcuslab
    @marcuslab  15 років тому +6

    Mitosis (cell division) typically takes 2-4 hours in these cells. However, these cells typically stay in non-replicative state (interphase) for at least 8-12 hours, then re-enter mitosis. So over the course of 24 hrs they may have 1-2 rounds of division.

  • @theduke6174
    @theduke6174 5 років тому +5

    agressive and chaotic

  • @flxmkr
    @flxmkr 13 років тому +2

    This frightens me. A few commented, if I interpreted the posts correctly, "oh! Well, this isn't real time. It's in a matter of days".
    True. But sit down with a pencil, begin with one, then multiply by two. Then multiply THAT by two, and so on and so on...it builds up too fast.
    Watch the video. Notice how quickly the screen fills up near the end as the seconds roll? Because EACH CELL is dividing at a phenomenal rate!!
    My maternal aunt lost the battle to BC, because she waited too long to g

  • @antonscottgoustin
    @antonscottgoustin 14 років тому +1

    What is stained or labeled here? What is the interval between snapshots?

  • @personzorz
    @personzorz 13 років тому +2

    Oh MAN! I wish it had gone just another hour or two - the bizarre, three-nuclei cell in the upper left was just starting to try to divide and there are tantalizing hints of truly bizarre spindles setting themselves up...

  • @agentfaffy
    @agentfaffy 15 років тому +2

    I'm aware that these are MCF-7 cancer cells and I was wondering how you were able to allow them to grow while recording them? Did you place them in a flask containing CO2 independent medium or did you use some other mechanism?

  • @todwstam
    @todwstam Рік тому +2

    how fast are they growing…? also hi from 2022

  • @awesomeisi92
    @awesomeisi92 11 років тому +1

    What kind of microscope is that?

  • @xahkdlys119
    @xahkdlys119 12 років тому +2

    That gives me chills~~~

  • @naheedakhtar4815
    @naheedakhtar4815 Місяць тому

    How can you stop breast cancer cells from dividing is this possible with diet or herbal medicines

  • @antonscottgoustin
    @antonscottgoustin 14 років тому

    What is the significance of the tiny persistent dots, are they remnants of the Flemming body?

  • @Hosedinho
    @Hosedinho 8 років тому +1

    trying to.get into a profession that involves looking at live cells whether it be cancerous or not. also a degree that involves research into finding a cure for disease... help plz

  • @ConorC96
    @ConorC96 13 років тому

    If a horse can run as fast as those cells, it could win the whole kentucky durby.

  • @vourok
    @vourok 14 років тому +2

    When I was watching this, I was like, "HOLY HELL! I didn't realize it was that bad". Was that in normal time?

  • @sen_on_youtube
    @sen_on_youtube 11 років тому

    so is this how and entire lump is formed hmm interesting and are those protoplasm attaching itself with one another... but protoplasm is inside the cell how can they used as adhesive cells

  • @loxy777
    @loxy777 13 років тому +1

    if they divide at this rate.. whats gonna happen next!!! m scared!

  • @marcuslab
    @marcuslab  14 років тому

    @antonscottgoustin most likely a protein aggregate inside the cell. they are too motile to be a microtubule organizing center and are not right up against the nucleus. all of the fluorescence you see is only from the tubulin:gfp protein.

  • @marcuslab
    @marcuslab  11 років тому

    It is a spinning disc confocal microscope.

  • @marcuslab
    @marcuslab  14 років тому

    @antonscottgoustin tubulin:gfp so you are seeing the microtubules. off the top of my head it is about 10 min per timepoint

  • @personzorz
    @personzorz 10 років тому +1

    Awww man you cut off too early, I wanted to see what happened to the giant trinucleate cell

  • @marcuslab
    @marcuslab  14 років тому

    @vourok It was over 48 to 72 hours

  • @marcuslab
    @marcuslab  15 років тому

    They divide by mitosis. Only reproductive cells divide my meiosis and have half the number of chromosomes (haploid).

  • @vita64
    @vita64 13 років тому +1

    Why on earth would anyone have an abortion debate on a scientific breast cancer mitosis video?

  • @Thor-uq3bi
    @Thor-uq3bi 5 років тому +1

    Is this real time

  • @ginatrue5716
    @ginatrue5716 Рік тому

    I think the c cells don't know when to quit. Got to be a way to convince them their job is finished. Maybe an internal injury or poison is triggering c cells non stop.

  • @marcuslab
    @marcuslab  14 років тому

    @bk344 Spinning disc confocal

  • @sunnytnguy
    @sunnytnguy 12 років тому +1

    If we can break down atoms into pieces how come we can't we stop these cells from multiplying ?

    • @mike4ty4
      @mike4ty4 5 років тому +2

      Actually, we can. The trick is how you _just_ stop them, and not stop the other cells in the body from doing what they need to do normally, because the two are so similar to each other. There's a saying that goes something like that cancer is very easy to kill; the trouble is avoiding killing the patient along with it. Cancer is actually a terribly inefficient pathogen - consider how that it usually takes a typical cancer years to go from inception to finally killing the patient, while that a bacterial infection can do the same in days or less, depending on species. The real problem with cancer is in its _similarity_ to normal body tissue. This both helps it evade the immune system _and_ makes it very difficult to target with treatments that _also_ won't end up killing all the normal tissue the patient is made of along with it.

    • @JOHNNYwxw
      @JOHNNYwxw 5 років тому

      These cells worth zilions :)

  • @wesKokigen
    @wesKokigen 12 років тому

    @DeadlyInertia Haha that is cute. :3

  • @spicytuna62
    @spicytuna62 13 років тому

    @ProLifeChristian Just goes to show how twisted the world is...

  • @flxmkr
    @flxmkr 13 років тому

    By the way, my aunt never had kids.

  • @kawaiinitz31
    @kawaiinitz31 14 років тому

    we all have cancer cells but they are dormant. woo, I hope they will just sleep forever inside my body

  • @sk874158
    @sk874158 12 років тому +1

    Yeh then and at the end of the video them getting to chemotherapy then they half shit themselves !!!

  • @JonahStratos
    @JonahStratos 12 років тому

    um.

  • @kevtyan
    @kevtyan 13 років тому

    quick get some trastuzumab on that shit!

  • @flxmkr
    @flxmkr 13 років тому

    Afraid of getting checked out?
    Best case: being told "not cancer" will give you peace of mind.
    Worst case: Confirmed cancer (what you were fretting over, anyway) but early treatment gives you a better chance of survival.
    Get checked out!

  • @Imthatguyx10
    @Imthatguyx10 8 років тому

    3 ppl have breast cancer o.0

  • @mizamazor
    @mizamazor 11 років тому

    breast cancer ever!

  • @RSXSera
    @RSXSera 15 років тому

    perhaps you should first learn grammar/spelling before microbiology

  • @Hosedinho
    @Hosedinho 8 років тому +1

    trying to.get into a profession that involves looking at live cells whether it be cancerous or not. also a degree that involves research into finding a cure for disease... help plz

    • @SDias22
      @SDias22 6 років тому +2

      Hussein Aly biomedical science

    • @blehbloop6584
      @blehbloop6584 5 років тому

      Biochemistry is a degree very involved with cancer research. If you want an in depth investigation of cancer, biochem is the best degree