Isotype switching | class switching recombination | Antibody class switching | antibody diversity

Immunoglobulin class switching, also known as isotype switching, isotypic commutation or class-switch recombination (CSR), is a biological mechanism that changes a B cell's production of immunoglobulin from one type to another, such as from the isotype IgM to the isotype IgG.

[@manalidhotre268]

Amazingly explained in detail 🙂 very easy language gud teaching helps me to better undertood I really liked this video plz keep doing👍

[@tomasmalinauskas2892]

Amazing man, that´s a perfect review of a theme that takes a long time to understand!

[@zizoilham]

So class switching is simply T dependent activation ?

[@xenzif4764]

As far as I know both no affinity and high affinity get destroyed by negetive selection and only T cell with low affinity survives through positive selection

[@TilleTheo]

Great video but the sound was not too good.

[@rudrakshisharma3128]

I have immunology exam tomorrow. This is so helpful and lucid to understand. Thank you 😊

[@czechmeoutbabe1997]

Arpan the GOAT

[@layeredmusic13]

hi, class switching can also occur before germinal center formation

[@latifaalnaemi412]

Amazing !!!!!!

[@RookieGamerz-3110]

I have a doubt. The region where NK-kb and Stat1 bind , in that region is the AID recruited? I can't understand this part. Plz help me

[@dstan16224]

Truly an incredible explanation Arpan! I was finding it so difficult until I saw your video.. Thank you very much and take care!

[@swetathakur7227]

This is the best explanation I could ever found .. thank you

[@juliettese5630]

Amazing ! Thanks to you i've understand in time for my exam this notion ! It is very well explained thank you !

[@almasfathima5511]

Thank you very much. Now the concept is more clear

[@yousradjoudi4500]

thank you so much, I'm a french med student, it was a very difficult topic to me

[@irshadahmad642]

Salute to your art sir.... Your are great and intellegent teacher... I always search for your videos if I need any topic

[@yoaimou9798]

Cool work man , clear and clean keep up

[@mahela1993]

This was perfectly clear! Thank you very much. :D

[@f-man3274]

Thank you, sir Arpan. I am a medical student who tries to understand immunogenetics and your channel is the best thing I could hope for

[@prashantpathak6589]

Tomorrow in my immunology exam...