How do mitochondria contribute to health and disease? - Peter McGuire

Peter McGuire, Ph.D, is an investigator in NHGRI's Medical Genomics and Metabolic Genetics Branch. Throughout his career, Dr. McGuire has been focused on improving the care of patients with disorders of mitochondrial metabolism. His NIH Clinical Center protocols, the NIH MINI Study, is the first organized effort to study immune function in patients with disorders of mitochondrial metabolism, which aims to demonstrate that these patients can be informative regarding the role of mitochondria in immune cell function.
The NHGRI Short Course in Genomics offers science educators the opportunity to hear lectures and receive teaching resources from leading researchers, clinicians and staff. Topics include complex diseases, sequencing technologies, brain and behavior, bioinformatics, gene editing, the human microbiome and ethical issues in genomics research. More: www.genome.gov/shortcourse

[@shoot-n-scoot3539]

Very in-depth lecture. Thanks.
But, I was hoping to find out more about the correlation between aging and mitochondria. I presume we have a prolonged mitochondria die off when we get past 44 years or so. It would be interesting to know more about that; what triggers the die off, why we don't make more mitochondria to replace what has disappeared. Thanks.

[@Peter-gu4zc]

Our body is superbly designed, indeed. This is our duty to take a good care of our mitochondria. Thank you Dr. Peter McGuire and other scientists for bringing all the info to us on this platform, so we can be enlighten what to do to stay healthy or to battle dysfunctions or diseases. All the very best in 2024!

[@xenobob2773]

Mitochondria so cuuuute!

[@Eliza_and_Odin]

I was not the target audience for this, but it was fascinating nonetheless. Thank you for the simple and accessibly worded explanations!!!

[@doctorinyourkitchen982]

Excellent!!! Thank you!

[@hyperbolicandivote]

Thanks for helping understand.

[@coastwalker101]

Great talk, I learned a lot. Thanks.

[@elizabethlumapat1350]

Thankful, we learn a lot.💟

[@stephen_pfrimmer]

Thank you!

[@ramanandfoundation7778]

Thanks for everything ❤️ Sir 🙏You are great person and scientist😁🙏 💗

[@draganmirkovic9377]

Besides red blood cells, which other cells does not have mitochondria?

[@shvonned.burkemsncrnpagpcn619]

Amazing talk! Thank you 🙏🏽

[@owenamys-roe4008]

man, i love this video

[@peterbeauclerk]

Thanks for sharing this information!

[@user-zh8wi9dv6n]

Transplanting new, healthier mitochondria without mutations, then we work to reproduce them

[@hiljim01]

i would like to learn about the effect on autism

[@namunamu9027]

10^100 Thanks.

[@heplamp8041]

The only thing I got to say about this I wish I had read these articles before my arteries become plugged I need a quadruple bypass now too late to run

[@christopherellis2663]

The essential information has been around for decades

[@christopherellis2663]

So, death is loss of mitochondrial function?
"Close Approximation "
or " proximity "? Americans are so nonstandard in their usages, that we are left guessing at what was meant. It seems that complexity in speech is seen as a mark of education.

[@tony538]

Get to the point please, good information but need a day to finish

[@mangos2888]

Booooooooooooooo