Multiple Sclerosis Vlog: MAVENCLAD (Cladribine) for MS
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- Опубліковано 29 чер 2024
- In this video, I share my opinions on Mavenclad (cladribine) to treat relapsing Multiple Sclerosis. To learn where this medication ranks and if it can be used during COVID19, then start watching this video right now!
The Boster Center for Multiple Sclerosis accepts all major insurance carriers and accepts consults from around the globe, both in office and via telemedicine. www.BosterMS.com or call 614-304-3444 to schedule!
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COMMENT with your thoughts and questions about Mavenclad (Cladribine) for MS below! I look forward to reading and responding!
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NOTE: Make sure to talk to your provider before ANY treatment decision. We hope to educate, empower and energize those impacted by Multiple Sclerosis. This channel consists of a collection of formal lectures and informal video clips about MS to help education others. These videos do not provide medical advice and are for informational/educational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any of our videos. They are just to help educate you about the condition guys!
I look forward to your questions and comments below! #Mavenclad #Cladribine #MultipleSclerosis #WeHaveMS
Dr. Boster, I had thyroid cancer and a thyroidectomy in 2012. Presently I'm on aubagio but I just got 2 new lesions on my thoracic. My doc suggested mavenclad. Also I'm 64. What do you think?
Please answer my question dr. Aaron. Thank you. I wish you were my doctor, but I am far away.
I completed year 2 of my Mavenclad treatment July this year. Definitely the easiest treatment and more comfortable than copaxone.
Now I just get on with life as normal until something changes. 😊😊😊 It's awesome.
Since starting treatment my MS has been stable. I was highly active.
Congratulations. I hope everything is still stable for you
How are you doing today and your mris? Thank you
would love to know how you are still doing 2 years later
Great video. I might do one on cladribine at some point. It is always interesting to read about Gavin Giovannoni's experiences on his blog.
i started Mavenclad last november and this has been my best year yet having MS.
Thank you, Aaron! My son has just finished his first year of Mavenclad, in the midst of the pandemic, and your perspective is really useful.
#StrongerTogether
Thank you so much for making these videos, doc.
I'm lucky to be Australian. We have excellent healthcare over here and so far my only expense has been for hospital parking.
That being said, having 24/7 access to your UA-cam channel is an absolute blessing. Like everyone else who's been diagnosed, I've had a difficult few weeks accepting it and learning what I can about MS.
A person who lives in the UK recommend I watch your videos, your knowledge and kindness is literally helping people all around the planet!
Cheers, ya legend!
Hey Doc! I am from the UK and it's cool to hear you talk about Barts MS in London; my MS specialist is involved with them. She is a very accomplished woman and my visits with her come free of charge via the UK's National Health Service (NHS). I feel very lucky to have her and to be on Tysabri free of charge.
Do you have any overseas patients from the UK? I imagine the NHS doesn't cover overseas treatment!
Thank you , Dr. Boster.
I wish Mavenclad would work for PPMS.🙏
About taking Mavenclad in Covid times. I took my treatment in January and February (year 2) so when this pandemic exploded and things were at their worst, I was basicly at my lowest in terms of white cell count. Also this second year, I have had problems getting it back to normal and I have had some issues with my liver (nothing too bad, after all). At certain moment I couldn't even go to the hospital to get the tests I needed to know how things were going because it was too dangerous. So it has been quite an scary experience mainly because the timing couldn't be worse.
Great Video! I am from Canada and currently waiting to start year 2 - though it has been delayed 5 months because my lymphocytes didn't recover quick enough. So far no progression though, and that's the goal!
Thanks again! It's great to get different perspectives.
Finished first year 13weeks ago and starting to get more energy pain has eased so so much 🙌🙌
Thank you for your intelligent accessible video about Mavenclad. I'm interested in your reports as I have relapse remitting MS, diagnosed in Nov 1996, through repeated MRIs after developing symptoms.
It's always useful to learn more, especially as my original degree was in biochemistry. I inject three times a week with beta interferon and see my NHS MS Nurse and consultant for monitoring. Learning about drug alternatives is very valuable.
Again, thank you so much. I think good information is the best protection from anxiety! With best wishes, stay well.
Thank you Aaron, this has helped me! Very informative and to the point, just what I need. Much Appreciated.
Thanks for taking the time to put this one together Aaron B. Great to hear another voice on this drug. If MS was a frizbee you just threw a cool smooth grabbable amount of info. ( Imagine me in beach shorts doing a respectful slow-mo medieval-styled curtsy.)
This year is my third and my Dr said my last year in Mavenclad and I feel a lot better than the other years
Thank you doctor Boster. I appreciate you insight and opinions. I did not know much about Mavenclad before.
Super cool video. Thanks. I am on Mavenclad and I feel good. Hugs from Spain.
You created a good analysis in my opinion.
Thank you Doc for your opinion!!!
Many thanks Dr. For taking the time out to educate us. God bless.
❤
I just finished week 1 of my first year on Mavenclad! I feel great, there were no side effects, I could go on with my life like nothing happened. So one less thing to worry about as I continue. I can only hope it's effective long term.
I just finished year 2 week 1 meds. Can't wait to finish my meds completely.
Thank you, thank you, thank you😊
Thanks Dr. Boster for being so faithful to your online village.I look forward to your video every Monday morning! You are the best:-) Have a great day :-)
Look for you this morning and you haven't been on. I hope everything is okay and I'm keeping you and your family in prayer :-)
Woot woot excellent video Doc. I think you nailed it.
The initial fatigue is real, but I feel my MS symptoms are ( 🤞🙏🏻) less severe than previously were. Even with the fatigue. I’m only 2 1/2 months - 3 months in. I’m liking it.
Such an amazing doctor
Very informative Dr. B, thank you!🙂🤗
Dr. Boster recently found your channel, I see a few patients with MS. I do like your content.
Thank you very much Dr. Foster! Welcome to the channel and I look forward to reading future comments!
Thanks so much always for explaining everything your the best.😇
You are so welcome!
Hey Aaron thank you for the video, I am from gernany and I have to take my first mavenclad soon, the video helped me:)
Thank you. I am always getting papers on that and think it is just makes me toss it out. Thank you for the explanation.
Dr. Booster, if Ocrevus for MS is sending you the hospital every four months for UTI's and sepsis do you recommend switching to another drug. Am 61 yrs old with spms. Some damage on left side of body. Arm and leg.
Very informative.👍👍
Again :) you're undervaluing your penny on the table. We get it's opinion & we appreciate your mountain of heads up, good luck pennies.
Thanks for this video. I was interested in what you thought about it as it's what I am taking.
Please talk about ppms medicine
Thanks Aaron. A very helpful discussion.
My pleasure!
Thanks for another informative video Doc.
My neurologist called Tysabri the big guns which I am on . I'm sure this would have been another option if I wasn't on Tysabri
Thank you Dr. Boster
You are welcome
I did my homework @aaronboster. I will see you at 4 today lol
My sister is starting her first cycle of mavenclad tomorrow. This was very helpful. I have a better understanding of how I can support her now. Thank you!
Glad it was helpful!
Thank you, I wish I had rrms instead of ppma
Good experience ty
Thank you, Dr. Boster! Great video! Does Clarity trial give the absolute value of Mavenclad effectiveness (such as for example 20 people didn't have relapses in 2 yrs or so)? Manufacturers usually prefer relative value such as percentage compared to control group as #s seem to look better this way. Thank you!
I am so relieved to see so many positive comments, I start my first round in February. :)
Very clearly explained, thank you! Do you think that MAvenclad is effective in patients with SPMS that already went through with monoclonal therapy and still have some kind of activity?
Thank you so much Dr. Boster for this great video. I finished second year of Mavenclad 5 months ago and I feel pretty good. My worry is that my lymphocytes haven't dropped too much and I don't know if the treatment is doing what it's supposed to do. Actually, in this second year my counts haven't dropped but they have increased. I had a flu shot last week, can I ask if there is a chance for the counts to increase after taking the shot? Thank you in advance!
So far, I'm testing the waters on my first year with Mavenclad. My symptoms are so unpredictable (and the pain scale has increased again), my right eye's retina is already getting paler. Despite that, I'm not experiencing relapses although my RRMS is highly active, aggressive and advanced. Just my usual symptoms that hadn't abated after the double relapse last year. Thanks for this! I was waiting for anyone to cover on Mavenclad 😊
He spoke at a lunch for us last year.
Fantastic video! Thank you Dr. Boster. I'm about to start year two on Mavenclad and I have a ton of questions for my MS specialist, your video gave me a few more to ask her.
Glad it was helpful!
Thank you very much for your informations 👏👏 is this DMT just for RRMS? No trials for SPMS?
Another great video Dr B! I love that it targets both T&B cells. Compared to Lemtrada how quickly or slowly does it take for you immune system to build back up? Thanks as always have a great week ahead. #CrushingMS #AllDayEveryday #MS #5For5
Compared to Lemtrada, Mavenclad suppressed the immune response to a lesser extent and for a shorter duration of time. It's important to keep in mind that the efficacy of these two drugs is not the same.
@@AaronBosterMDlemtrada is more effective? Do you think lemtrada is better than mavenclad? Or kesimpta is better? Thank you
Thank you for another very informative, easy to understand video. Is there any prediction on how likely another follow up treatment would be and if there is any break through disease after, would you go to a different med or would you repeat the mavenclad cycle?
This is a VERY INSIGHTFUL question! I'd like to answer this in a follow up video sometime soon Andrea.
Thank you so much. Why not combine two types of medicine? For example Tysabri with Mavenclad.
Hi Dr Boster I finished my year 2 of Mavenclad on November 7. My MRI will be in January 2022 and I was wondering if Mavenclad will have any kind of impact, on my lesions, example will it lower the number of lesions, do you think it will, if anything , have an impact. Thank you Dr Boster for your knowledge and help with all of us with MS.
I finished my first year treatment in December. It's made me worse, 3 weeks after taking First weeks treatment, I started getting brain fog, fatigue vision. Three months in and I haven't been the same. I wish I hadn't taken it. I started with one symptoms to feeling drugged up everyday. Don't know what to do. Neurologist, suggested we re do MRIs. He doesn't know why I'm experiencing what I'm now
I am curious... how does Mavenclad compare to Lamtrada? Since they both target B and T cells. They havent seen the type of side effects in Mavenclad that they see in Lemtrada. With Lemtrada they have to test blood and urine for 5 years monthly for a few things (thyroid, blood cells or immune system not functioning properly (HLH)) then treat those rare things if you get them. So how do they stack up?
What effect would taking Mavenglad have on PIRA? ML&R, can't wait to see you 😄
Would this be something that could be used instead of one of the other pills when there is no breakthrough to warrant switching? Is it still considered a tier two DMT? This is something I'd like to discuss with my daughter, but I know insurance approval can be an issue.
Hi Doctor Boster. I have kind of a un related question, Is there any benefit or negative effects of MS patients taking MCT oil? Thanks!!
It's been almost 6 months since finishing my first year treatment. I'll be honest I still have some waking difficulty, but still have hope. Will be going in for my MRI next month to see if any decrease or new lesions. 🙏
hello Garpot, how r u know?
Hi @Garpot, just wondering how your treatment has been going since your last post. Hoping for the best for you!
Hey Dr. B! Are you going to doing a video on Kesimpta? I’m curious what your thoughts are on it and were it would fall with efficacy. Hope you and your family are doing well! ☺️
here you go: ua-cam.com/video/eFVkRIMuhDM/v-deo.html
@@AaronBosterMD thanks Dr. B! Switching from Aubagio to Kesimpta tomorrow!!!!! Nervous but excited about it! 😁😬
@@kristenlynnoliverhow are you with kesimpta? Your rmi
I actually am coming off of having thyroid cancer and my doc wants me to consider Mavenclad. Its between Aubagio or Mavenclad. Since cancer was mostly removed I can now be put on a med but Mavenclad is somewhat questionable since I already had cancer. Not enough info out there for someone like me.
Slow to find this, but have a question. Can this be used in progressive forms of MS? I’m looking for a treatment that doesn’t consistently suppress the immune system like Ocrevus since I’m aging.
Thanks for a great explanation!!!
Hi Dr. Boster! Curious if this would be a good replacement for Aubagio? My mother passed of breast cancer so I'm not certain if this would be a good idea. I'm still having exacerbations every 18 months or so and since I'm seeing a new doctor, I thought I may mention Mavenclad IF you think it would be safe, knowing the cancer issue?
Sonja, now you know I can't give medical advice over the interwebs! I always think communicating with your provider is a good idea.
I started the cladribine injection last week. I appreciate it if you let me how to manage the side effect if there is.
Besides, I would like to know whether Cladribine has possive effect on improving my mobility
I was due to start yr 2 early Dec. My lymphocytes were only .4. Now in mid Feb they are. 6. I was so fatigued yr 1 for 8 months I'm not sure I can do year 2. Was on tysabri 6 years then had reaction. I'm 50. I have had 6 other dmds. I'm so tired of this disease. Relapsed 1st yr mavenclad too
I apologize for the framing of my question: at 5:05 you mentioned follow up was challenging because patients were lost. Lost as in perished or (more hopeful) they were not able to be tracked down due to the length of time since? Maybe out living their best life due to great results?
Do you find that you run into issues getting insurance to approve Cladribine or Lemtrada first line?
I felt so sick when i was on Mavenclad.
Hi Aaron. Thank you for your video! In your video you said Mavenclad is the king of all pills, but not on par with Ocrevus. Is the efficacy of the Ocrevus infusions the same as the Ocrevus shot I could take at home? The reason I'm asking is because I was diagnosed with MS a couple days ago and my doctor suggested either Mavenclad, Ocrevus infusions, or Ocrevus shots I could take once a month at home. I love the convenience of the Mavenclad, but I want to take the best meds for my MS regardless of convenience. Thank you!!!
Ocrevus is in a hospital. At home is kesimpta... Are you taking which one?
Hi!
I had a very small attack on the last day of my first week of cladribine, and another attack 2 months after the second week of the first course. What are the timings of actions of the drug? , and would you consider "possible" the situation I just described?
What sort of patient do you think is most suitable for mavenclad?
this drug is (too good to be true)
i don’t know i feel something bad will happen after 2-4 years
Hi Dr,
I'm from the UK and currently taking Cladribine on my 2nd year. I have noticed and wanted your professional opinion about this that after my 1st year of taking Cladribine I've developed back pains. Mostly lower back pain which is aggravated when I'm sitting or standing for long periods of time.
I haven't experienced this before. I've heard that Cladribine can cause lower back issues, is this correct? Thank you very much.
OG MonSter Slayer here. I'm currently on Mavenclad. I began April 2020. Currently, the main side effects have been deep bruising, joint pain/Arthritis-like pain, and still have mild flares (SPMS). I've been on Ocrevus and Tysabri and feel that it is not as effective as the infusion meds. The biggest plus is short lived side effects during the week of taking Mavenclad. After going into Anaphylaxis during a Tysabri infusion and coding in the infusion room, I know a thing or 2 about side effects. The assistance program provided me with $0 meds. That was a sticking point: infusions are not covered with any assistance programs but a pill is.
Thx Doc!
P.S. can you please cover the following:
Clonus,
Balance tests,
Common Assistance Devices,
Insomnia,
MENTAL HEALTH vs MS,
Sjogren's Syndrome,
Common Co-existing illnesses,
Childhood MS,
Steroid treatments,
Eye health issues,
Tracking Rx side effects,
Personal MS tracking chart use,
PTSD/TRAUMA and MS
I have SPMS and am on Rituximab.... It doesn't seem to halt the disease 100% and am looking for something additional and not a substitute as I have to give some credits to rituxan for slowing down the progression, but, that isn't sufficient... I have doubts about the efficacy of HSCT for SPMS...
How are you doing now, if I may ask?
Hello Dr. question about the white blood cell. How low did it drop. Like 75% out of 100%. I'm a cashier at Walmart and my wife work at a daycare. We have 3 kids under 6. So i what to know if i going to get sick alot. Lol anything? 😁 thanks
Hi dr. Aaron, I am so undecided if I should change or not drugs, from Gilenya to this one, Mavenclad. It seems to me this drug is too good to be true, only two years and then? I am taking Gilenya for eight years and I am stable so far, but I am suffering with fatigue and headaches from Gilenya. I don't know what to do. If I leave Gilenya, I won't be able to come back, I was told, due to insurance. Please give me your opinion about my case. Thank you.
I started taking Mavenclad last year switching from bein on Ocrevus for more 6 years. I progressed the last year extremly fast and will go on Ocrevus again. Has anybody had similar experiences?
Interesting. I never heard of these meds Doctor. Been on Tecfidera, Tysabri, Copaxone, Ocrevus. Even though they say I'm now Secondary progressive, what would be something that would best suit that?
It would be best to ask your Doctor. The little details can make a big difference so knowing your medical history would be helpful. Contacting your local MS Society could be a resource to follow current studies and new medications. That background information can be helpful at your appointments.
@@maxanderson7871 We are never too old to learn, ask questions or give advice. Thanks hun, food for thought 🧠 ♡
Wow big audio drop around 7:30
Can Mavenclad cause acne on the face? Is it a hormonal imbalance that could be caused with taking Mavenclad?
Do I have to wait for Mavenclad to empty? Before the patient starts HSCT?
Can it help improve numbness ( also long term ? Numbness) can it reverse vibrate test to fell it back again or fell vibrate test better?
I am currently taking my y1m2d4. I am working full time in a public environment. Would it be wise to go on leave for a few months? Thoughts?
how was it for you? Im 20 yo and just starting med school and newly diagnosed with MS and will prolly begin with this drug, did you ever contract an illness while immunosuppressed?
can mavenclad therapy be interrupted? And can another therapy be started instead?
I take it but I’m scared in the future if any attack comes what should I take cortisone?
since mavenclad reduces lymphocyte counts, wouldn't that render prior vaccinations null? (asking because of the requirements of updated vaccinations before starting treatment)
What do you mean they were lost?
Hi, thanks for your videos , can I upgrade patient from Gilenya to Mavenclad and if so should I wait for lymphocytes to reach certain number before starting Mavenclad
ua-cam.com/video/EnRemOR5pmA/v-deo.html
I found my answer your lectures are more informative than Continuum !!
I have completed my first year of cladribine this month . I'm 30 yrs old woman who plans to have children. My question is how does the medicine effect my cycle and is it true that I may not be able to get pregnant?
Hello my dear doctor, I've been watching you with great pleasure from Turkey, with your permission I would ask you two questions. first one; Is mavenclad superior to gilenya and mayzent in efficiency? latter; When my wife cut gilenya due to pregnancy before, there were 2 rebounds. Dozens of active plaques occurred. We returned to gilenya after pregnancy, but now gilenya does not protect it anymore, my wife has frequent attacks. In the transition to mavenclad, we are afraid of rebounding again in the purification period, is it possible to switch from gilenya to mavencla without purification or keeping it too short? When we cut the gilenya and take a break for more than a month, very severe attacks occur. we have experienced this 2 times. That's why we are worried about changing medication. Thank you very much for your answer..
Bende bu ilacı alacam nasıl iyimi
Merhaba Yucel Bey, Ben de 7 yildir gilenya dayim. Ilaci bir kez 3 gun alnadim hemen atak geliyir. Doctor large simdi mavenclade gecnek ya da tysablri dusunuyor ya da gilenta devam...durundan epey endiseliyim. Yazacaginiz her geri donus beni cok mutlu edecektir. Cok tsk ederim. Ben bayanim.
@@SimpleEnglishHub-ben de yaklaşık 15 yıldır MS hastasıyım.bugün itibariyle mavenclad a başladım.bakalım bana iyi gelecek mi.gelişmeleri yazarım
Hi Aaron
Can it be used while on Tysabri
Aaron I’m from Australia I look forward to your post 😊
Melbourne here 👍
Such an amazing doctor