Diagnosis of Epidermolysis Bullosa: Modalities, Principles, and Usage
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- Опубліковано 8 вер 2024
- #basementmembrane #skin #butterflyskin #epidermolysisbullosa #skinattachment #epidermolysis #diagnosis
Introduction - 03:11
Diagnostic Modalities - 10:47
Clinical Examoination and History Taking - 15:15
EB Matrix - 19:35
Skin Biopsy - 23:18
Immunofluorescence Microscopy - 26:58
Transmission Electron Microscopy - 32:48
DNA [Sanger] Sequencing - 17:13
Further Reading - 42:25
End - 45:06
Further Reading:
1. Chapter 69 - Genetic Blistering Disorders. In: Rooks Textbook of Dermatology, 10ed. Pg-69.1, Griffiths C et al.
2. Chapter 32 - Epidermolysis Bullosa. In: Bolognia’s Dermatology, 4ed. Pg-538, David Fine J et al.
3. Chapter 60 - Inherited Epidermolysis Bullosa. In: Fitzpatrick’s Dermatology, 9ed. Pg-1011, Marinkovish MP et al.
4.Sarkar R, Bansal S, Garg VK. Epidermolysis bullosa: Where do we stand?. Indian J Dermatol Venereol Leprol 2011;77:431-438
5. Yenamandra VK, Moss C, Sreenivas V, Khan M, Sivasubbu S, Sharma VK, Sethuraman G. Development of a clinical diagnostic matrix for characterizing inherited epidermolysis bullosa. Br J Dermatol. 2017 Jun;176(6):1624-1632. doi: 10.1111/bjd.15221. Epub 2017 May 5. PMID: 27925151.
6. EB Matrix: www.eb-clinet....
Kindly correlate clinically how to approach a case what all investigations to be done and treatment options available in all discussion than the reach of video will be more otherwise very low will be there
Sir what is onion skin in eb
Kindly elaborate
Onion skin has nothing to do with eb. I meant to say that while diagnosing, we go from easier tests and examinations to complicated and costly tests. So, we diagnose by going deeper and deeper, layer by layer, to reach a specific diagnosis in eb. That is the onion skin approach. Thank you for your query ☺️☺️🙏
@@sabhderma Thank you sir.