2023 Recap: New Treatments and Approaches in

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  • Опубліковано 25 лис 2024
  • Donate to PCRI: pcri.org/donate/
    For more information, visit pcri.org
    Videos For Further Information:
    PARP Inhibitors: • New FDA Approved PARP ...
    PSMA: • PSMA & Newly-Diagnosed...
    Active Surveillance: • Active Surveillance 10...
    PROSTOX: • IMRT vs. SBRT & Reduci...
    Zepbound: • 2023 Update: Wegovy, O...
    1:08 What are the new PARP Inhibitors, Talzenna and Akegga?
    2:18 How effective has PSMA been at helping patients delay chemotherapy?
    5:08 What was the state of active surveillance in 2023?
    5:56 What is Prostox and can it apply to spot radiation?
    7:49 What was the state of Pluvicto as a treatment in 2023?
    10:02 How have Zepbound and other semaglutides affected prostate cancer?
    11:39 How has prostate cancer treatment been affected by all these new developments?
    13:26 Alex's conclusions
    Don't know your stage? Take the quiz: visit www.prostatecan...
    To learn more about prostate cancer, visit www.pcri.org
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    Who we are:
    The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.

КОМЕНТАРІ • 127

  • @robertdurkin1662
    @robertdurkin1662 10 місяців тому +137

    I am a physician that has stage four prostate cancer. I’ve read numerous books on prostate cancer, and nothing comes close to being nearly as useful or informative as this site. THANK YOU!.

    • @DCGreenZone
      @DCGreenZone 10 місяців тому +5

      Amen to that!!

    • @johnq5307
      @johnq5307 10 місяців тому +3

      Hey doc, stage 4? Have you had a radical prostatectomy? Are you doing ADT? I’m Gleason 8 local and had IRE right before thanksgiving.

    • @pinotwinelover
      @pinotwinelover 10 місяців тому +2

      Nothing even close because it includes the human element in the decision-making the personality types, etc. it's very personalized even through video

    • @robertwhite154
      @robertwhite154 9 місяців тому +3

      Agreed 100%! This channel got me through the worst stages - diagnosis, MRI, Biopsy, Pet Scan, and Surgery - with hope and confidence. Thank you so much ❤

    • @DCGreenZone
      @DCGreenZone 9 місяців тому +3

      @@robertwhite154 Here's hoping that PSMA PET becomes the mandatory standard, regardless the cost of the hardware. Everywhere.

  • @hokkitt
    @hokkitt 7 місяців тому +3

    Watch every video from northern Sweden. This couple have saved my mental health

  • @zpoedog
    @zpoedog 9 місяців тому +22

    If you have prostate cancer, I am convinced this is the best place to start your search for real information. I survived Gleason 9 prostate cancer with spot radiation . Thank you, PCRI.

    • @jabster58
      @jabster58 7 місяців тому +1

      How long has it been now?

    • @zpoedog
      @zpoedog 7 місяців тому

      @@jabster58 I am going back for my 6 month checkup after radiation treatment in a few days. I'll know more then.

    • @zpoedog
      @zpoedog 6 місяців тому

      I had my 6 month and everything seems to still be OK..

  • @meganote
    @meganote 10 місяців тому +20

    You guys are an awesome resource in the prostate cancer community!

  • @DCGreenZone
    @DCGreenZone 10 місяців тому +24

    Bless both of you and the education you provide. ❤

  • @eddiegardner8232
    @eddiegardner8232 10 місяців тому +15

    PCRI is the first thing I recommend people visit when I encounter a new patient online. They can answer so many questions for themselves just by watching the videos, and dodge a lot of "bro-science" misinformation they might encounter just googling around.

    • @robertweber3140
      @robertweber3140 10 місяців тому +2

      Agree! Been watching for the last 10 months.

  • @seanoshea8102
    @seanoshea8102 8 місяців тому +5

    Thank you Dr Scholz and Alex. You are doing amazing work!! To: Anyone who may be able to help, I am a 65 y/o, (active and otherwise very healthy male) who had a radical prostatectomy 12 years ago- and after being undetectable for yeas I had a PSA of 1.44 in 2022 and then measuring 8.53 on 1/4/24 and6.97 on 01/12/24.
    With very recent Pet/CT and MRI, 2 small lesions were found.(the larger of the 2 is a 0.8 cm restricting and enhancing lesion within the right side of the prostatectomy bed adjacent to the anterolateral aspect of the rectum)
    I believe proton therapy would be appropriate treatment as opposed to photon radiation and intermittent hormone therapy (following an initial long period) if the PSA becomes and continues to be undetectable instead of 2 years of continuous hormone therapy.
    Is there anything in my situation (All Chart data Below) that would require me to have photon radiation instead of proton or preclude me from intermittent hormone therapy?
    -------------------------------------------------------------------------------------------------------------------
    Date: Feb 13, 2024
    Dx: Prostate CA-Gleason score of 4+3=7 (GG 3) iPSA 4.21 involving 15%of the specimen, negative margins, positive extraprostatic extension.
    His final pathologic stage was T3aN0. Current Tx: bi/Pred, Eligard, XRT Prior Tx: Radical prostatectomy May 2012
    Oncology History: This is a 65 y.o. caucasian male referred re: rising PSA remote from his radical prostatectomy in 5/2012 at U of C. He underwent a robotic assisted laparoscopic radical prostatectomy in May of 2012. His final pathology revealed prostate adenocarcinoma with a Gleason score of 4+3=7 involving 15%of the specimen, negative margins, positive extraprostatic
    extension. His final pathologic stage was T3aN0. No adj XRT or hormone therapy was administered. His PSA since the time of surgery had been undetectable.
    Date Value
    3/10/2012 4.21
    11/29/2012

    • @njboesman
      @njboesman 8 місяців тому +2

      Thats alot of info to put on a public forum, my advice is to contact PCRI directly and have a convo with them for guidance.

  • @blackdoglodge
    @blackdoglodge 9 місяців тому +8

    I'm stage 4 metastatic PC for over 4 years...Had 9 rounds of chemo, 88 proton beam therapy radiation treatments (68 on prostate and 20 on "hot spots")...Lupron the entire 4 years....Then (at my request) I was given high doses of testosterone (400mg) every 28 days along with the Lupron and Prolia (every 6 months) for bones....When I received the testosterone my PSA was around 7-8....Almost instantly I actually felt like a man again...Libido returned along with energy....But my PSA started rising...after 7 months of the testosterone shots my PSA was 124...My Oncologist stopped the T shots....after a month psa was 60...Due for labs next week....My T levels are almost undetectable...I'm 85 years old and now without any testosterone there's really nothing to look forward to ....I'm going to ask for at least some testosterone cream...So far I have no bone pain so Lu177 is probably on the back burner for a while....IMO a man cannot feel like a man without Testosterone....Too bad it feeds the cancer...

    • @pinotwinelover
      @pinotwinelover 9 місяців тому +3

      Yeah, this testosterone issue is quite a irony because they don't show any indications that testosterone itself starts the cancer but if it metastasize is it definitely feeds the cancer very weird I'm not sure what I would do at 85. It's not easy for me to say at 85 I might wanna feel like a man more than be alive so I'd probably just keep doing the testosterone not because I want to have sex or whatever just because like you said without it you're just existing but I don't know what I would do. That's a difficult decision not easy to say.

    • @blackdoglodge
      @blackdoglodge 9 місяців тому +4

      It's been 4 months without any Lupron and I'm NEVER taking a shot of that crap again...While on it I gained 15 lbs, the usual hot flashes, Feeling crappy, and all the other side effects.. I have lost 10lbs by just not having it in my system...Even though im 85 I'm still pretty active...Swim 3-4 times a week, but without much Testosterone it takes a day to recover (and a nap)...When I was getting the T shots I felt 25 yrs younger...Felt like getting Lucky all the time...Using a pump and having T in my system it was no problem to get a Woody....I've come to the conclusion that I've had a great run and am not going to take anything just to get my PSA down (while feeling lousy)...If it got to zero, so what?...It's not going to get rid of any of the cancer...Right now I feel pretty darn good and am not going to rock the boat...I know my Oncologist probably wont give me the 400mg of T, but maybe some T cream..He says eventually I'll produce testosterone...But my clock is ticking...Its not all about the sex, its about just feeling better...I don't have any bone pain yet but if that starts I'll consider the Lu177....Worst case scenario Mexico is not far from San Diego and I can get anything there...Thanks for the reply....@@pinotwinelover

    • @pinotwinelover
      @pinotwinelover 9 місяців тому +2

      @@blackdoglodge I don't blame you just kick ass for the next three or four or five years and enjoy. Good luck my friend.

    • @blackdoglodge
      @blackdoglodge 9 місяців тому +2

      Thanks for the reply and kind words...3,4,or 5 years would be a stretch but I guess anythings possible...I'm thinking a couple at best...Last time I saw my Oncologist I commented that I was in the 4th quarter just trying to get into OT....With a deadpan face he said..."You are in OT !"....So I guess that nailed it...If I was 60 or 65 I'd probably be looking at any and all possible procedures to post phone entry into the "Turf Club" but I'm gonna just go with what I've got...Wife and family are well taken care of so that's the main thing.....If you get a chance Google ... Bryce Olson..A patients story ...Pretty interesting..Bryce has since passed but it's a very informative story...Be sure and watch the vid....Good luck in your journey....@@pinotwinelover

  • @BGAllenWarEagle
    @BGAllenWarEagle 10 місяців тому +12

    I am very grateful for your work. Just one of your videos has potentially changed the course of my life (medically). I was diagnosed with a high grade cancer and the urologist scheduled me for the standard CT and bone scans. Because of your video on the PSMA PET scan, I asked for that instead. ThePSMA PET scan picked up a tiny particle of prostate cancer in a lymph node close to my prostate. It was small enough that it would not have been seen on a CT scan. Thus, because of your video educating me, a more appropriate course of treatment was put into place.

    • @terranceolson9134
      @terranceolson9134 9 місяців тому +2

      Same here. 2 very small spots on lower left lymph nodes and seminal vesicle involvement. My urologist told me if they can spot radiate those two small lymph nodes spot, complete 6 week radiation and 18-24 mo. hormone therapy there's a good chance my treatment can be curative. I had a decipher test after my biopsy that showed my cancer is at the low end of intermediate/unfavorable (.46 on 1-10 scale) which means my cancer is not highly aggressive even though it's a 4+3 Gleason and has managed to get outside my prostate. Medicare pays for the decipher genome test which is about $5K.

  • @systemicexplosion
    @systemicexplosion 8 місяців тому +4

    Just diagnosed with 4+3 intraductal carc both sides of base in prostate,. 26 PSA, but PSMA PET scan shows cancer is localized in Prostate. Initial biopsy path results at local clinic did not identify IDC-P, went for 2nd opinion at Univ of Chicago Med and their path folks found the IDC-P. Poorer prognosis for IDC-P, a more aggressive variant, but the newer treatment options give me hope of extended life, especially with localized containment. A friend in east TN suggested a novel treatment of bee stings. Fascinating...LOL!! Ready to go to war!! Do not go gentle into that good night!!

  • @kimsmart11
    @kimsmart11 2 місяці тому +1

    Much thanks, your video is very helpful and informative.

  • @kvmalley
    @kvmalley 10 місяців тому +17

    These videos have been so informative, thank you for your continued efforts! I’m low grade, early detected and carefully researching my options. I called your help line, and John called back the same afternoon! He was very helpful, and told me if he were me, he would be getting SBRT. That’s what I’ve been leaning towards the entire time and called Moffitt Cancer Center in Tampa not far from me. They have it, and I’m following up with my primary care today to discuss my referral approval for Moffitt.

    • @tomcaruso8087
      @tomcaruso8087 10 місяців тому +2

      What is your Gleason score and PSA if I may ask?

    • @kvmalley
      @kvmalley 10 місяців тому

      @@tomcaruso8087 Gleason is 6 and PSA is around 4.9 maybe a hair over 5 this week. Was just checked again last Friday, and I forget. But I’ll find out for sure shortly, it’s still rather low considering. Hope all is well with you @tomcaruso8087, praying your prognosis is similar. Do your research!

  • @TK-123
    @TK-123 10 місяців тому +13

    This was so outstanding for the information delivered.

  • @MyCousinGrandpa
    @MyCousinGrandpa 10 місяців тому +9

    Thanks Alex and Dr Scholz for a great “year end” summary. As a patient currently in remission I’m thankful for what you are doing to keep us all informed. You can count on my ongoing support.

  • @rickcertano2767
    @rickcertano2767 10 місяців тому +11

    Just starting out on this journey. PSA growing from 4-12 in 3.5 years. MRI and biopsy scheduled. This whole journey created a lot of anxiety but thanks to the two of you I have an idea how to proceed. Thank you so much!!

    • @richardbennington323
      @richardbennington323 10 місяців тому +2

      Try to find a good support group in your area for prostate. It definitely helps with anxiety.

    • @billm201
      @billm201 10 місяців тому +5

      Hormone therapy will buy you years to research your best approach. Most Dr.'s want to take an invasive surgical approach for obvious reasons. Stay calm, you have plenty of time to figure things out.

  • @Mark_Lacey
    @Mark_Lacey 10 місяців тому +7

    Diagnosed 3 months ago with Stage 4 Gleason 9 PC. This video and especially the advice at the end from Alex was very informative, thank you both so much.

  • @johnmensah4412
    @johnmensah4412 10 місяців тому +8

    Very informative. Alex, you ask all the pertinent questions. Good job.

  • @toppie5700
    @toppie5700 9 місяців тому +3

    you guys are brilliant , Im from South Africa and the only real info you get on prostate cancer here is over the net , so thank you its much appreciated

  • @pabinder
    @pabinder 9 місяців тому +4

    Thank you. Thank you. Thank you.

  • @paulinevpola8176
    @paulinevpola8176 6 місяців тому +1

    Amazing. just wanted to thank you presenters for clear, comprehensive and informative presentation. i knew near to nothing til here 👏👌❤

  • @marymary122
    @marymary122 9 місяців тому +1

    Thank you for such an informative video. My husband is facing surgery or radiation. PSA 13.9 with Gleason 8. He is 60 and active and in good health. We are (Americans l) living in Switzerland. Again...thank you for doing this!

  • @doug4357
    @doug4357 10 місяців тому +3

    Thank You. I very much appreciate these videos you produce. I have joined your PCRI site and am much more calm about my prognosis of prostate cancer. Best Regards Doug

  • @laurierowley1703
    @laurierowley1703 10 місяців тому +6

    THANK YOU!!! Great & so helpful. We love you guys

  • @johnnysalazar3951
    @johnnysalazar3951 10 місяців тому +3

    Thank you for your educational information on this important subject.

  • @grandmasterstash9766
    @grandmasterstash9766 5 місяців тому

    Very grateful for the information provided by PCRI. Post 8 weeks successful radiation treatment, 0.1 PSA. Two PMSA scans confirming no spread to the bone . Time to talk to my oncologist about the possibility of ending the hormone therapy after one year based on the new study discussed in your recent videos. The idea that continued surveillance and intermittent radiation may take the place of the androgen blockers is so encouraging. Thank you doctor for your clarity. You are indeed a champion for those of us who find themselves on this journey.

  • @edwardbertorelli7358
    @edwardbertorelli7358 10 місяців тому +2

    Great recap.... vital info

  • @williamvandyke3501
    @williamvandyke3501 10 місяців тому +2

    Great video Thank You.

  • @Daisy-bt7li
    @Daisy-bt7li 10 місяців тому +2

    Thank you so much for all of this info! So helpful and encouraging .

  • @alaskacanoe6837
    @alaskacanoe6837 9 місяців тому

    Great interview and questions asked..
    It clearly is one of the better options ..
    $$$$ = problems for many of us ..
    Lots of money in the cancer game..

  • @richardbennington323
    @richardbennington323 10 місяців тому +1

    We use a lot of his videos and his book these two are great thank you so much for all your information

  • @robwells230
    @robwells230 10 місяців тому +4

    Thank you for this update..
    Would you consider doing an update on the availability of cancer drugs that become available in generic form???
    The outrageously expensive costs of patent drugs are preventing some patients from getting optimum treatment.
    However, once these drugs become generic, many more patients can benefit. For example, Zytiga / Abiraterone. and Casodex/ Bicaludamide
    are now quite affordable..

  • @RuthSurfield
    @RuthSurfield 10 місяців тому

    Am 76 and have PC grade 3a after prostatectomy 2 years ago and PSA has been 0. Decided on PSA tests every three months but have alot of anxiety when due. Love your informative videos as they help prepare me in case of BCR. THANKS!

  • @jeetujeet27
    @jeetujeet27 7 місяців тому +1

    Thanks for the great work you people are doing. Dr. Scholz is god sent angel ...is there any chance to consult Dr Scholz online for prostate cancer consultation?

  • @steveweiss7736
    @steveweiss7736 10 місяців тому +1

    This is a Fantastic resource I’m so glad I found you. Keep up the good work on keeping us informed. It’s sad that most urologists don’t have the time to keep up to date on new technology and methods of treatment. I have my next appointment coming up and PSMA PET scan is on the list. Unfortunately I believe it will be a battle as I started the conversation via email with my doctor and he already started to shoot it down…Instead of saying let’s discuss when we meet up next time.

    • @terranceolson9134
      @terranceolson9134 9 місяців тому

      If your doctor is shooting down a PSMA PET Scan, I would get a second opinion. The dirty little secret is that it's your life and you're on your own to make sure sure you're doctor is capable of giving you the best advice. I got a new urologist after I learned my first urologist no longer specializes in prostate cancer.

  • @jamesscott1189
    @jamesscott1189 8 місяців тому +1

    at 75, metastatic prostate cancer, zytiga for 4 years, okay, stopped working,
    Then started aggressive GARLIC, 4 t0 5 cloves a day, seemed to stop metastasis,
    Now on Orgovyx, Bad constipation for 2 mos, now 81... READ ABOUT GARLIC

  • @funtunesforkids
    @funtunesforkids 9 місяців тому

    Would love to see a video about the new “micro boost” radiation procedure a radiation oncologist just told me about yesterday. Thanks so much for what you’re doing!

  • @njboesman
    @njboesman 8 місяців тому +1

    Just starting my journey with PC, I'm 64 and just got my biopsy results back 2 weeks ago. My Gleason is a 6 (3+3) with a group 1. Biopsy was targeted based on a lesion found in MRI which showed a .7x .4 cm lesion on right posterior. More concerning is the biopsy also revealed an Intraductal carcinoma on the left side of the gland. Waiting for a genomics report and really undecided on the type of treatment, looking for guidance and advice. I will be seeking a second opinion after consulting with my urologist. Comments welcome

  • @roger1uk676
    @roger1uk676 10 місяців тому +3

    Excellent as always

  • @divyasharma-rp6je
    @divyasharma-rp6je 10 місяців тому

    Also my Gleason score is 3+4.

  • @patricktrussell7465
    @patricktrussell7465 10 місяців тому +3

    How about AOH 1996 ?

  • @eearts
    @eearts 10 місяців тому

    I found medical grade ozone and ewot therapy great for my autoimmune issues! It’s going to helps saturate my body with much needed oxygen .. how simple!! I’m surprised it’s not used MORE! It’s quit easy to get and it can be relatively inexpensive

  • @teddy06410
    @teddy06410 10 місяців тому

    Can you do a video on the HoLEP procedure?

  • @lagunaray
    @lagunaray 10 місяців тому +4

    I was on active surveillance for prostate cancer for 5 years. I chose not to have another biopsy or treatment until cancer was detected on an MRI. My urologist was very prominant in the industry and was ready to perform a radical prostatectomy. I opted for proton beam therapy and have been thrilled with the results. Is there ever a case when a radical prostatectomy is the best or only treatment a man should consider?

    • @stephenedwards3832
      @stephenedwards3832 10 місяців тому +1

      Thanks for the report. I’m checking into that now, if I can’t achieve the outcome I’m looking for holistically

    • @Mrbynby
      @Mrbynby 10 місяців тому

      I'm 72 and Gleeson 8 metastasized to several areas. I've done radiation and xtandi with eligard shots. The psa is way down but side effects are not fun and I worry about possible heart problems. Should I seek alternative treatments . My urologist seems unresponsive to any questions

    • @infinityrecordsusa1482
      @infinityrecordsusa1482 10 місяців тому

      I believe the questions are valid but the oncologist is the best one to ask. My urologist as well somewhat in dark with answers as such. Also a second opinion with another Cancer Specailty Hospital is advised so you can tell if on the proper treatments. Peace to you. @@Mrbynby

    • @lagunaray
      @lagunaray 10 місяців тому

      I am sorry to hear your cancer has metastasized. I have not looked into the treatment options for your situation. Urologists are surgeons who are trained to surgically remove the prostate. Urologic oncologists are urologists who undergo additional training focused specifically on oncology (cancer prevention, diagnosis and treatment). These doctors specialize in treating cancer in the urinary tract and the male reproductive system, such as cancer in the: Prostate cancer. Bladder cancer. If faced with your situation I would educate myself and seek out an oncologist to learn about options. Best wishes.@@Mrbynby

  • @colemant6845
    @colemant6845 10 місяців тому +1

    When a PSMA indicates Metastasis in a few lymph nodes and the prostate... YET follow up biopsies/pathology results of prostate and lymph nodes are ALL benign. This is my case. How can this be?? My urologist has decided to put me on a "Wait & See" tracking the PSA for several months. This scares me.... Is this correct?

  • @andersbring882
    @andersbring882 9 місяців тому +1

    Do you know anything about this new system, warming upp the tumor,
    Physician Finder
    Find a clinic in the US
    The following clinics in the US offer focal laser ablation (FLA) of localized prostate cancer using the CLS TRANBERG® Thermal Therapy System, either as a routine clinical procedure or as part of a post market clinical study.

  • @michaeldelucia7352
    @michaeldelucia7352 10 місяців тому +2

    👍

  • @strong2thefinich
    @strong2thefinich 9 місяців тому +1

    Where does obesity come into play exactly with the prostate?

    • @njboesman
      @njboesman 8 місяців тому

      as with most things related to health and wellness, obesity only makes things worse.

  • @davidgeorgea
    @davidgeorgea 9 місяців тому +1

    😮

    • @davidgeorgea
      @davidgeorgea 9 місяців тому

      I had my prostate removed in 2010 and had radiation.
      Later Hormone treatment then after my PSA stayed Les than Zero. I was advised to have a holiday.
      Now my PSA is 9.5 l am advised to go back on hormone treatment once more.
      So l have had good quality of life , l am 77yrs old and have survived now for 14yrs .
      And prostate cancer has not stopped me from having a normal life .
      And hopefully l will stay well going forwards .

  • @Ed-zr3fm
    @Ed-zr3fm 5 місяців тому

    I had robotic prostate surgery, My PSA went from 8.2 to 4.7. What does that mean ?

  • @mikeoniones667
    @mikeoniones667 10 місяців тому

    Will provecto work on low psa like half a point 0.50 ?

  • @pkg111
    @pkg111 6 місяців тому +1

    Please talk obstructive symptoms in. Patient has seen recent therapy. Call prosthetic cancer.

  • @carladerenzy3674
    @carladerenzy3674 9 місяців тому

    As always, extremely helpful.
    I just finished my Pluvicto/Lutetium treatment and my metastatic cancer is significantly reduced with no new foci or any additional growths since treatment began in April. PSA is .7 down from 525 in March, '23.

  • @barbarameehan113
    @barbarameehan113 4 місяці тому

    My hubbie was scheduled for a psma scan and last minute told him it would be $1000.00.
    Wow, is this the norm for having this test. We have medicare and a supplement. Can't afford this.

    •  8 днів тому

      We have United Healthcare Plan G, PSMA was covered 100%. Wishing you good health.

  • @stephenedwards3832
    @stephenedwards3832 10 місяців тому +4

    I’m curious on your opinion on the keto diet with intermittent fasting coupled with long term fasting 8+ days. And your belief on autophagy, apoptosis, and ferroptosis, and how this all specifically apply to prostate cancer? Appreciate your work! 🎉

    • @ricknowak4582
      @ricknowak4582 9 місяців тому

      😊 You have a great idea bro. I HAVE changed my diet. I would love to fast but that's a tough one. But in excellent idea to add to your treatment. I BELIEVE IN FASTING LIKE YOU DESCRIBE. I am going to give it a TRY!!!

  • @drew2757
    @drew2757 9 місяців тому

    It’s my understanding that a patient with a pace maker would not be suitable for a PSMA PET scan. Is this true.

  • @agarcia5461
    @agarcia5461 10 місяців тому

    I recently had a Pet scan end of 2023 with PSA of 1.0 after 2nd recurrence and it did not detect any cancer. How is it that PSA pet scan spoken so highly of? I've lost hope

  • @salsamink
    @salsamink 10 місяців тому

    Great video. Can you go deeper into safety for caregivers taking care of an elderly family member living with them that will receive Lu-177(Pluvicto). The precautions they give caregivers to take after treatment seems impossible to take care of a love one that is elderly that receives Pluvicto. Example: Stay 3 feet away for a couple of days, use different bathrooms, have them sit in the back seat when leaving treatment day. How can you care for them using these precautions? What about someone that only has one bathroom in their home? If someone sits in a seat they just sat on, is a danger. Does that person leave behind radiation on things they touch that can expose others? If yes, what removes this from surfaces. What if the elderly person has diarrhea from the radiation, how does the caregiver clean up the area safely and does radiation stay behind in that area? Sorry if these are stupid question. Why stay away from children and pregnant women longer days than other people? Does radiation exposure not cause risk to non pregnant adults the same amount of days.

    • @FightingProstateCancer
      @FightingProstateCancer 9 місяців тому +1

      I don't have an experience with Pluvicto. But the Pluvicto's Radiation safety says that "It’s fine to be in close contact with another person for a short period of time (such as a brief hug)." So I don't think that using the same bathroom should be a problem. It should not be a danger if someone sits in a seat they just sat on. If the elderly person has a diarrhea then you should use gloves. Same with urine.
      Try to follow the guidelines as best as you can. If that would be a problem then there are also protective "hazmat suites" but that would probably be too much and they are quite expensive.
      Problem would be if you, as a caregiver, would be pregnant. Then you would have to find someone else who would take care of the family member.
      Children are more vulnerable that's why the longer days. Same applies to pregnant women - they have a new child inside.
      Radiation could damage the children.
      You may also ask if increased iodine intake would help you.

    • @salsamink
      @salsamink 9 місяців тому +1

      @@FightingProstateCancer thanks for replying. It’s really hard because the doctor office hands you a paper with extremely strict precautions, but then you ask them how to keep those precautions as a caregiver and the answer is “everything will be fine”. We will take care of dad no matter what, but I wish we had real facts on the effect on an adult’s body as caregivers. Mostly when we will be more then brief contact right after treatment helping him walk to car and getting in the car. Or maybe, it’s just that they don’t know because it hasn’t been studied. Which will be fine. I just need to know. Again thank you. Will look into iodine.

    • @FightingProstateCancer
      @FightingProstateCancer 9 місяців тому

      The safety measures are mainly for the first days after the application of Pluvicto because of the half-life of the Lutetium and because many of the Lutetium will not be bound by the body and simply will be excreted, mainly by urine.
      There is a study "External radiation exposure, excretion, and effective half-life in 177Lu-PSMA-targeted therapies" www.ncbi.nlm.nih.gov/pmc/articles/PMC5897276/
      It says that after 12 hours, approx. 70 % of adminstered activity were excreted, primarily via urine.
      The average half-life was 40.5 ± 9.6 hours. So it means that after 40.5 ± 9.6 hours the remaining radiation was halved, after 81 ± 19.2 hours the remaining radiation was at the quarter of the initial radiation, ... and so on.
      You search the exposure to caregivers. The study says: "The safety of 177Lu PSMA administration to staff and caregivers was also emphasized in the previously cited study by Demir et al. The authors measured radiation doses delivered both to administering staff and family in 23 patients and found that the mean dose rate at 1 m after 4 and 6 h was 23 ± 6 μSv/h and 15 ± 4 μSv/h, respectively. They also found that the mean dose received by close family members was 202 ± 43 μSv, measured for 5 days post-injection with an optically stimulated luminescence dosimeter. "
      Link to the study "Evaluation of radiation safety in 177Lu-PSMA therapy and development of outpatient treatment protocol": iopscience.iop.org/article/10.1088/0952-4746/36/2/269
      Radiation exposure is measured in micro-Sieverts [µSv] - here are examples for context:
      ------
      10 µSv - Average daily dose received from natural background
      20 µSv - Chest X-ray
      40 µSv - A 5-hour airplane flight
      600 µSv - mammogram
      1 000 µSv - Dose limit for individual members of the public, total effective dose per annum
      3 650 µSv - Average yearly dose received from natural background
      5 800 µSv - Chest CT scan
      Source: www.nuclear-power.com/nuclear-engineering/radiation-protection/equivalent-dose/sievert-unit-of-equivalent-dose/sievert-gray-becquerel-conversion-calculation/
      -----
      So it means that the average dose rate at 1 meter distance after 4 hours was 23 ± 6 μSv per hour. Which is like 1.15 ± 0.3 chest X-rays every hour.
      After 6 hours it was 15 ± 4 μSv per hour. And after 5 days the average dose received by close family members was 202 ± 43 μSv, which is like 10 ± 2 chest X-rays or 1/3 of mammogram.
      Read please short article "Three principles for radiation safety: time, distance, and shielding" www.ncbi.nlm.nih.gov/pmc/articles/PMC6037814/
      Even though it's about different type of exposure (C-arm fluoroscopy), it's useful. Mainly the end where the author compares the three principles and emphasizes the distance as a shield against radiation - The distance principle. Quote:
      "... However, if a pain physician stands double the distance from a radiation source, his radiation exposure will reduce to 1/4"
      As for the iodine intake. Maybe it would suffice to eat more fish, seafood, tuna, ..., or increase the intake of iodised salt instead of iodine tablets. I don't know this. @@salsamink

  • @codyjones3708
    @codyjones3708 10 місяців тому

    Do you still have to have chemo before being eligible for pluvicto... thanks.

    • @ThePCRI
      @ThePCRI  10 місяців тому +1

      Here is a video where Dr. Scholz discusses chemo and pluvicto: ua-cam.com/video/a4e0NsEbk_U/v-deo.htmlsi=ej4AyJ_VMZcwz9oA
      To our knowledge, yes.

  • @ricknowak4582
    @ricknowak4582 9 місяців тому

    P s a twelve point eight. Pi R a d five lesion. Don't know what to do. I plan on getting a second opinion from a different oncologist, And a different M R I I and a different reading On that lesion. If it WASN'T for that darn LESION I wouldn't do ... ANYTHING ! I am ZZJUICING and esting STEAMED tomatoes and OTHER things healthy. Any thoughts PLEASE.

  • @robertweber3140
    @robertweber3140 10 місяців тому

    I am surprised why they had no update on Tulsa-PRO?!?

    • @ThePCRI
      @ThePCRI  10 місяців тому +2

      We have an update coming!

    • @robertweber3140
      @robertweber3140 10 місяців тому

      @@ThePCRI Thank you. It's what I'm planning on.

    • @ThePCRI
      @ThePCRI  9 місяців тому +1

      Here is our new video on Tulsa Pro. We hope this helps: ua-cam.com/video/TjdV5qAEbdA/v-deo.html

    • @robertweber3140
      @robertweber3140 9 місяців тому

      @@ThePCRIthank you!!!😊

  • @lagunaray
    @lagunaray 10 місяців тому

    Assuming prostate cancer has not metastasized, Is there ever a case when a radical prostatectomy is the best or only treatment a man should consider?

  • @ForgeKnife
    @ForgeKnife 10 місяців тому +1

    I have advanced metastatic stage 4 prostate cancer. Also diabetic with neuropathy of feet. I started taking nuphoria gold vitamin supplement and it has reduced the pain. I want to know if it could be feeding my cancer. The nerve doctor youtube channel said no but I would like another opinion.

    • @DCGreenZone
      @DCGreenZone 10 місяців тому +1

      Look perhaps at sodium stabilized R Lipoic Acid for the neuropathy, not medical advice, check with your physician/oncologist.

    • @fabdawgpoker7835
      @fabdawgpoker7835 10 місяців тому +1

      My dad has had it since 2010 and just told him it went to his bones and lymph nodes. He’s on hormone treatment and they wanted him to do 6 rounds of chemo but he doesn’t want to do that just yet. They also told him he can live longer with this and it’s very scary. Typically how long do people have when it spreads to bones and lymph nodes? He 71 and seems very healthy with no bone pain

    • @ThePCRI
      @ThePCRI  10 місяців тому

      For specific questions and information, please reach out to our Helpline here: pcri.org/helpline

  • @divyasharma-rp6je
    @divyasharma-rp6je 10 місяців тому +1

    Yes. Stage 4. Metastatic. To the lymph nodes in the pelvis,abdomen and the supraclavicular. Also to the bones. Fortunately the lungs & liver were spared.
    Gleason score was 3+4.
    The last PSMA pet scan showed no significant nodes or bony mets. PSA steady at 0.04 since 4 months. Prostate 27cc.
    My question was how long does Abiraterone & Lupron continue.

    • @FightingProstateCancer
      @FightingProstateCancer 9 місяців тому +1

      Have you discussed this with your doctor?
      Your PSA is good. You may consider radiotherapy to prostate + pelvis.

  • @divyasharma-rp6je
    @divyasharma-rp6je 10 місяців тому +2

    I’m on injection Lupron every 3 months and Abiraterone 1000mg + prednisone 5mg for 2 years now. My PSA is 0.04 since 6 months and PSMA scan in March 22 was encouraging with remission.
    Should I continue with this treatment and for how long.
    I am 69 years old.

    • @divyasharma-rp6je
      @divyasharma-rp6je 10 місяців тому

      Please reply

    • @divyasharma-rp6je
      @divyasharma-rp6je 10 місяців тому

      Sir please let me know if I have to continue indefinitely on the same medicines

    • @infinityrecordsusa1482
      @infinityrecordsusa1482 10 місяців тому

      Stage 4 ? Metastatic ? What area in your body , I am only 4 months into this journey but my goal is remission. Let's share. Peace to you.

  • @eliseokeefe1140
    @eliseokeefe1140 10 місяців тому +2

    My boyfriend has metastatic prostate cancer. He's in clinical trials now but was not selected to take the Pluvitco, so he's been on the standard radiation (3rd time). What is the source for 50% of patients who use Pluvitco realizing a PSA decline and remission? Where can Pluvitco be received outside of clinical trials? Thank you for these informative videos. We greatly appreciate them and have learned so much.

    • @hn5460
      @hn5460 10 місяців тому

      INITIOmedical in Burnaby, BC, Canada offers it. It is called Lu-177 PSMA treatment. They are identical drug/treatment.

    • @hn5460
      @hn5460 10 місяців тому

      INITIOmedical in Burnaby, BC, Canada offers it. It is called Lu-177 PSMA treatment. They are identical drug/treatment.

  • @panamafred1
    @panamafred1 10 місяців тому +3

    Hey, I've got an idea. How about not eating inflammatory foods? Sugars, carbohydrates, seed oils (canola, corn, soy, etc.) all cause inflammation. I'm 75. Two years ago I was 40-pounds overweight, pre-diabetic, arthritic, had high blood pressure, gum disease, brain fog, difficulty urinating, and on and on. Then I quit the inflammatory Standard American Diet and switched to eating the Carnivore diet. In these two years ALL my maladies have reversed and gone away. I'm now healthy, have no diagnoses, and take no pills. I drive with confidence with no brain fog. This Carnivore way of eating has saved my life. I'll never go back to eating those nasty sugars and carbs and plants in any form.

  • @jimmyellingtonrealtalkradio
    @jimmyellingtonrealtalkradio 10 місяців тому

    Everyone wants the Chemo specific treatment based on these informational videos. Seems logical. But then enters the Insurance and “healthcare” industry. Basically a sham buy the Fiat driven system we have digressed to.