Hormone Therapy as a Primary Treatment |
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- Опубліковано 11 лип 2024
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0:25 When is hormone therapy advisable as a primary treatment?
4:09 What is the risk of cancer recurrence after hormone therapy?
5:39 At what PSA score is hormone therapy most effective?
6:38 Do patients usually start with a second generation hormone therapy?
7:46 What is the monitoring process like for patients undergoing hormone therapy?
9:01 When is hormone therapy preferable to radiation therapy?
11:11 How effective are hormone therapies at shrinking the prostate?
12:24 Which hormone therapy has the most anti-cancer efficacy?
13:16 When and why should a patient consider hormone therapy as a primary treatment?
15:04 Alex's conclusions
16:52 If you need more help
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Thank you so much to Dr Mark Scholz and Alex 👍😀Can have podcast on the removal of both testes to control cancer cells spread as I am having prostrate cancer too. TQ again
I have some great news that may also be very helpful to others on this great site! Per ThePCRI's advice I stopped my vigorous freestyle swimming kick (2 1/2 hours per session twice a week) for one week and then had my PSA retested. My PSA dropped by 4.7 ng/ml! It appears that bicycling is not the only exercise that puts pressure on the prostate and causes the PSA to rise.
Superb information as always, stage 4 Gleason 9, Prostap hormone therapy is my only treatment and has been for over 2 years, i was told by oncology that I would be on this for life , no offer of radiation or surgery, at the begining I felt short changed, not so sure now, PSA at 0.1, I am 65 still working in construction, my living room is now a gym, main downside for me , no interest at all in sex, the ability is still there but the urge is non existent, I live alone and as Dr Sholz put it I have had my fun, it really does not bother me, life is great, think about what you have got, forget what you have not got. Thank you so much for all the videos you do, by far the best source of information available Phil
Thanks for your post. Did your diagnosis also include metastases within your skeleton? And what was your starting PSA level ?
Stage 4, Gleason 4+5=9, initial PSA of 1,300, Mets all over spine, some ribs and elsewhere. Oncologist also says ADT will be forever. Urologist asked if I wanted surgery. I asked him if it will help, he said no. SMH. He then asked if I wanted chemo. I asked if it would help, he said no. SMH.
PSA down to 0.09 after 3 months and stable for 24 months. I’m 71.
Fellow Gleason nine patient here. You’ve got a great attitude. Best wishes for success on your journey.
I just had my first PSA test done a month ago after having 44 days of radiation and my first jab of Eligard in December 2023. Happy to say my PSA went from 3.65 from May 2023 to 0.07 as of June 2024. I will meet with my Oncologist next month to go over everything. I will say I've had no interruptions with my life as i've continued working and need to increase my exercises. The only downside or should i say side effect is the dreadful hot flashes and some tightness in my legs though at 68 I might be dealing with sciatica and arthritis. I just had my second jab of Eligard a month ago so with these dang heat waves and hot flashes I am a sweating wreck. No desire for sex either but I've had so much over the many years so what's important to me is LIVING. Not in a serious relationship right now so its ok. But Glory to God I'm still standing.
@@Vincent50 amen brother!
In 2021 I was diagnosed with metastatic prostate cancer that spread to my torso. Aggressively doctors put me on Lupron and Aberiterone. My side effects were severe and effected me greatly. My liver count was high and I have brain fog and fatigue, joint pain. I later switched to Xtandi that helped some, but I haven't been the same. The therapy handicapped me from doing my job. Since my prostate cancer is metastatic I'm advised to be on hormone therapy indefinitely. However 2 years 9 months later there's no sign of cancer. I had the doctor do a Petscan and CTscan and no cancer. I'm currently on a break from the medicine doing lab work once a month to monitor my PSA. I stopped in March 2024. I'm hoping the Lupron gets out of my system and have a sign of testerone with no cancer. Doing another biopsy is something I picked up from this video.
If you have to go back on hormone therapy, I suggest that you look into ORGOVYX instead of Lupron. It’s out of your system in about 60 days and testosterone recovers far more quickly. Good luck on your journey with prostate cancer.
What was your initial psa when you were diagnosed with prostate cancer?
@@schmingusss It was a 39. Very bad.
@@majesticc247
My PSA was 42.
After 6 months on Eligard CASTRATION and 25 fractions of 68 Grey IMRT, my PSA DROPPED to .28, then .008, then to .006, then to ZERO.. now, my testosterone has recovered just a bit to 150 and my PSA last test was 0.2.
I refused further ADT after the first six month shot because of the horrific side effects , and that poison shit has left me partially castrated even two years later.
I really have appreciated your interviews with Dr. Scholz. Very timely for me, I am 70 years old. I have recently been diagnosed with prostate cancer. I had a Prostate MRI done 3/18/24. Then a trans-perineal prostate biopsy with MRI fusion 6/5/24 . Then a PET - PSMA 6/26/24. The PET scan shown no metastases . My biopsy Gleason scores were as follows: 2 - 3+3, 3 - 3+4 . There was no INTRADUCTAL CARCINOMA present in all samples. Of course I have been researching my options on how to proceed. One therapy I have been looking at is Proton therapy, it would be nice to hear Dr. Scholz's view on this therapy in comparison to other forms of radiation such as gamma ray. I have read that protons can be more precise and can travel through the outer tissue and deposit most of its energy in the prostate. I don't know if that's the case or a sales pitch for proton therapy. Thank you so much for all you and Dr. Scholz are doing to help people like me.
Good treatment - Hormone therapy, blocking testosterone. Testosterone is the reason PSA rises. Lupron is a good option - as proven by my husband, Gleason 9 never had rosibg PSA, diagnosed incidently, immediate Prostatectomy, 4-1/2 years PSA still less than .75, (point 75, less than 1), PET scan shows lymph node involvement, slow rising PSA Lupron shot followed by radiation. Testosterone still zero, PSA still undetectable 2 yrs later.
Ahe at initial diagnosis, RP: 66
Age at finishing radiation: 73.
Age today: 75
Stay alive. He's thriving.
Thank you for your information you are by far a expert in this field.
Thank you for this. My testosterone is at the lower end of ‘normal’ so suspect doing away with it totally for a while won’t have such bad side effects🤔 My NHS Oncologist is determined to get me radiated too! I’m trying to avoid radical treatments. (3+4 =7, no metastasis on recent PSMA pet scan, fit healthy 58 years old, on off label drugs and protocol in How to Starve Cancer).
Great video...have been having ADT for 5 years (74). T3aN1M1 - Gleeson 8, diagnosed PSA 22, Dec 2019,
The last 2 years Lucrin 6 month injections. My last 3 PSA have been 8.6 - .35 - .07 The .07 reading (taken last week) is unusual in that it is at the end of the 6 month inject.cycle whereat PSA readings usually start to increase ! ). Will be interesting to hear what my Oncol. reads into it ,if anything !. Very happy to continue with ADT with associated side effects (hot flushes etc etc).
Your videos give me hope.
One of my concerns with ADT is that it could temporarily suppress the symptoms of prostate cancer and make it difficult to tell if the radiation or surgery treatment actually worked. I would be concerned that the symptoms could be hidden by the ADT only to emerge after ADT is discontinued.
That is also a concern for me as well. I got a shot of Lupron (3 month lasting shot) and then had 50 radiation treatment sessions (40 for prostate and 10 for the tumor in my pelvic bone). I am waiting to see the psa results at the 3 and then 6 month marks to determine what to do going forward.
@@tedmetre6933 It takes an additional 3 months for the 3 month lasting shot to clear the system (total of 6 months). The question at the 6 month point is: Is it the ADT that is keeping the PSA low or the Radiation treatment. I don't see how someone could tell if the radiation worked as long as they are on ADT. Good luck and hoping for the best outcome for you.
They seldom mention dangers of possibility of heart attack and stroke from using adt. Go for lutetium 177 ,if you can afford it ...
You can do MRI or pet scan to confirm disease has been eradicated.
Wonderful intelligent information.
Another informative session
This site was randomly recommended to me many months ago. It has been invaluable to me for information I needed after having been diagnosed with elevated PSA and a lesion found on the prostate via MRI. I garnered much information over the months leading up to and including the biopsy. It prepared me for the possibility of a cancer diagnosis with the hope of an eventual cure and good recovery. After finally getting the biopsy and diagnosed with a diseased prostate, I am happy to report no çancer was found after 14 samples were taken. However, my biopsy does not answer why I have intermittent elevated PSA levels. Perhaps because I sometimes have inflammation due to UTIs or maybe prostatitis ? I am 73 years old.
@@TERRY-cb2ku Enlarged prostate?
@@ralphcherry617 Yes, but other factors are involved. I am on tadalafil 5mg daily for urinary function, and it works fairly well. Here are the most significant findings of my biopsy. Segmental prostatic acinar hyperplasia, diffuse prostatic acinar atrophy and focal acute inflammatory infiltration. Some samples had multiple findings. Three samples showed no significant pathological abnormalities. In total 14 samples were taken. Possibly two were taken from the lesion itself. Overall, I consider myself lucky.
Same here. I've have three biopies over 9 years. The second two biopsies were performed after the MRI showed two lesions each time. All were negative. My last PSA was at 4 but I've had as high as 10. My last results showed "cronic inflamation" of 1/2 of my prostate. I see my Uro every six months and were monitoring.
@@ralphcherry617 Fooltube has deleted my previous reply to you. My prostate is enlarged but evidently not to a high degree. According to the report, which I have a copy of, three different diseases are present but no cancer is involved. After doing some research, I have a theory about the rising PSA levels and I have discussed this with my doctor. Despite my age, 73 , I am very active most of the time and I do strenuous exercise most days. Crunches, sit ups, weights and elliptical. Which can cause a rise in PSA levels. Even having sex 5 to 7 days before PSA blood work can cause higher numbers. Also riding a tractor, ATV, motorcycle for any length of time can add to your numbers. But in the end, although not a perfect outcome, I thank God for answering a lot of prayers.
Gleason 4+3=7 RP, Radiation, round of Taxtore, Lymph Node Positive, 2 years Lupron- PSA down to 0 - took a 2 year holiday PSA started creeping up to 5. Started Lupron 3 month shot, PSA to undetectable in sixty days. Can I take an immediate holiday or is there a set time period?
Good afternoon Maam/Sir, is Metastatic Prostate Cancer that had spread to the bones curable?
What about Darilutimide?
I was given both radiation and ADT. 😮
I’ve been given both and still on ADT.
I would like to hear Dr. Schultz comment on
taking Abiraterone alone in lieu of Lupron.
Is it as effective in dropping Testosterone levels???
And after stopping Abiraterone, how long does it take to recover testosterone to normal???
It seems difficult to get straight answers to these important questions.
I am on 1st and second gen ADT for 2 years, plus radiation. sure wish things like Extandi would be covered by normal insurance. Zytiga and Lupron for 2 years is a nasty cocktail. I have no idea how I am going to make it through another 12 months plus 6 months recovery time.
@@therealpeterburke peter, I’m a Gleason 9 Stage 3 patient. Already had salvage RP after failed brachytherapy, finishing up salvage radiation and on two years of first and second generation ADT. A fellow patient suggested ORGOVYX instead of Lupron for first generation so that’s what I’m taking. Less hot flashes and fatigue. I am on Zytiga for second generation. I do resistance training, four days a week and walk or cycle vigorously seven days a week. Hot flashes are not too bothersome. Libido is not existent... Fatigue was manageable until radiation started. That should improve or so I’m told. You may want to look into switching to ORGOVYX instead of Lupron. You’re out of pocket could be manageable, depending on your insurance plan. Testosterone recovers far more quickly with ORGOVYX instead of Lupron. How Zytiga will affect things remains to be seen. Do as Google search for Mark Cuban cost plus pharmacy to reduce your cost of Zytiga, which goes under the generic name Abiraterone. I don’t relish the thought of being on this for 24 years either but M committed to doing everything I can to beat this disease. Good luck on your journey.
@@therealpeterburke Sorry to hear... This is a heavy treatment... 3years!
What was the last measured PSA?
Lupron has miserable side effects. They say that you "might" experience them, including hot flashes. Well, you will experience them, and your life will never be the same. If you want those side effects, go ahead and take Lupron. If you think you will not have the side effects, think again. They will never tell you the truth.
"Might experience" was accurate for me. If you do have side effects, you are part of the minority but I understand that being there feels like 100% and very bad. You may have to do some of the suggestions to limit the affects. You feel like a victim, but you are in far more control than you sound. I am 77, tested low testosterone anyway so maybe I didn't miss it so much but never had hot flashes that I am aware of. I am very active, farming, fence building, clearing trees, milling them down to lumber and doing woodworking projects. That may affect my experience. I do know that if I feel fatigued and want to just sit, I'll go outside, do something and fatigue goes away just as I was told.
So true, when I don’t do regular exercise I feel horrible, depressed, hot flashes, soreness etc. when I do though most symptoms disappear
Don’t do it!-I plead with u not to allow this to happen to you-the side effects are horrendous and they won’t share this with you
ADT + prostate destruction = _woman_ 😩
no ADt + no prostate destruction = DEATH
But alive.
I respectfully and strongly disagree. I suggest you purchase the book “surviving prostate cancer” by Dr. Patrick Walsh. It may change your perspective.
@@spitfirekid1almost killed me you don’t know squat
Orchiectomy = Almost Woman
Why was Lupron discontinued?
Why was Lupron discontinued? AbbVie would like to inform you that this product has now been discontinued globally across AbbVie due to a lack of demand with newer alternatives available. Nov 10, 2022
When are we going to figure out how to get an erection after hormone therapy. remission for 5 yrs. back up to 5.9 No side effects testosterrone 721. took pd5 in hibator only semi / i do not want to get cut. & radiation is out,. was to spread out at the time. treatment should not be so invasive for an erection. we got the cure lets figure out the limbedo . part. what do you think!