5:51 In here, you mentioned Na reaching DCT and proximal collecting duct stimulates RAAS, and subsequently causing hypokalemia. However, RAAS actually turned off if macula densa sensed larged sodium (increased GFR). The reason why RAAS was activated is that loss of Na in NaHCO3 would lead to intracascular depletion, and subsequently activate RAAS, and further causing potassium loss.
Thank you so much for making this topic so chewable. This really made me understand the topic instead of memorizing the table of the difference in RTA type II vs Type I. 🎉
10:43 : typo - It should be Distal RTA (Type 1) ... i have written proximal RTA (Type 1)
Well explained, thank you ..!!
Very hard topic. You made a complete video without making it complicated. Thanks a lot
THE BEST LECTURE ON RTA. THANKYOU SIR
5:51 In here, you mentioned Na reaching DCT and proximal collecting duct stimulates RAAS, and subsequently causing hypokalemia.
However, RAAS actually turned off if macula densa sensed larged sodium (increased GFR).
The reason why RAAS was activated is that loss of Na in NaHCO3 would lead to intracascular depletion, and subsequently activate RAAS, and further causing potassium loss.
So in a state where RAAS is activated, if you supply with NaHCO3 load, Na will be reabsorbded and potassium will lose more.
Thank so much sir from uk 🇬🇧
Thanks
Thank you so much for making this topic so chewable. This really made me understand the topic instead of memorizing the table of the difference in RTA type II vs Type I. 🎉
Glad it was helpful!
Thanky you so much sir...very clear explanation..😊
At 10:43 it states "Proximal RTA (Type 1)." Shouldn't it be "Distal?"
true . .. thanks for catching it ...
Sir font ka size mt chota kriye bs 😢
If you want a goob mnemonic think about type 1 - one - H+/ type 2 - two - BIcarbonate, type 4 - 4 looks like an A - Aldosterone
thanks.. that is cool . . .that is going to stick in my memory forever. ....