Doctor Reacts to The Apothecary Diaries | Maomao Fact-check
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- Опубліковано 25 вер 2024
- Hey I'm a Doctor working in the UK and in this video I react to and fact-check scenes from the apothecary diaries anime from a doctor's perspective.
In todays video I fact-check Maomao's medical knowledge of poisons and their impact on the human body, as well as her ability to diagnose numerous ailments afflicting the imperial court.
We'll be looking at lead poisoning, sleep walking, aphrodisiacs and soo much more.
Along the way we'll be keeping a percentage accuracy of Maomao's medical knowledge and finally conclude how accurate the apothecary diaries anime is.
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1) Solo levelling
2) Makito Shisho transformation
3) Juggernaut Anatomy break down
4) Healing animations in anime
5) Suggestions.......
I think the Juggernaut anatomy or Makito Shishio might be good
Blue Eyed Samurai please
React to mortal Kombat
As a doctor you should watch Doctor Elise, it's from a korean novel and it also has a manhwa (comic), it is very interesting! It has a reincarnation, and the MC bring her modern medicine knowledge to the XIX century
I wanna see the 2ed half of this show
The author of the novel mentioned that she relied on 19th century medicine to develop the story, so that is a great point to keep in mind before judging Mao Mao's knowledge.
Was about to write this as well... Also, the medical knowledge between the east and the west might also have been very different at that time too.
YES thank You for posting this :D i was about to post the same
Really? I thought the author said that the premise is based on Ming Dynasty China (13-17th century)You could tell the dynasty by its clothing as well
@@ftu2021 The clothing and architecture yes, but the medical knowledge is from the 19th century
@@leviathanx0815 she was trained by someone that had Western training.
10:50 Did you just call out the servant girl from Imperial China like period for not having the modern medical treatments for sleepwalking 😂
I kinda disagree with you on the Li Hua's treatment.
You're right that tea won't works as an antidote, and that sauna would dehydrate the consort.
But Maomao's intention was to force her body to eject as much fluids as she can. And by keeping her constantly hydrated, plus having her sweat, she would achieve that goal.
Yeah, it's a bit frustrating that he treated those scenes as completely separate points, when they're very much connected in the manner you described. Dehydration would be an issue in the sauna, but the patient has just been described as being given a lot more fluids than normal. lol
Not to mention she literally said in the sub that she was making her take a diuretic tea, not just normal tea. There are diuretics that have been known for hundreds of years since it is a pretty easy to see symptom.
The idea here is clearly that Maomao wants Li Hua to sweat out any remnants of the lead makeup she may still have in her skin and pores, and essentially cycle out any poison in her body fluids out. I'm not sure how effective that would be, but we must remember that Maomao is an apothecary from ancient times. By the standards of medicine at the time, her methods have more logic and common sense than most insane stuff other doctors might suggest, such as leeching and bloodletting.
Not to mention that a common tactic to deal with intoxication is keeping the patient very well hydrated (since a good deal of toxins and drugs are eliminated in urine), but since Mao Mao can't just hook her with an IV and drinking solely water in large quantities can make someone nauseated and vomit (which not only dehydrates the patient but has the risk of bronchoaspiration) I'd say that giving her something flavorful is a good way to ensure the patient'd body accepts the treatment more effectively!
I think Maomao was trying to
1. Dilute the poison in her system by increasing the fluid intake
2. Flush the poison from her stomach and kidneys by frequent urination
3. Slowly increase the fibers in her meals to help with bowel movement
4. Sweat out the poison from her skin since it was skin absorbed
Tell the truth, Doc. Part of you actually wishes Maomao were real so you could hire her, don’t you? 🤣
Silver can detect arsenic, and sulfur based poisons, so that was accurate as well.
There have been no studies conducted on it, I believe they were said to tarnish if in contact with arsenic, but there have been no peer reviewed studies on it. Aside from that I feel he was too harsh on a 19th century girl by recommending using modern medicine and medical knowledge, as well as deducting 10 point every time maomao got something wrong while only adding 1 point for what she got right.
@@1cho456 Google: Toward surface-enhanced Raman scattering using electroless substrate for trace arsenic detection and speciation
It shows how silver discolour in the presence of arsenic at concentrations much lower than we initially assumed (1ug / L) (for the record LD50 for arsenic is 150mg- 1g for a typical adults)
Also Silver reacting to sulphates is a known fact, it is hard to publish something that people consider common knowledge.
It does, but the silverware would take a long time to tarnish. So that fact was half-and-half
i'd like to remind you that this takes place in ancient china. so knowledge about sleep walking is probably not as advanced as what we know today lol
I believe you're underestimating just how much of a simulant effect something like the chocolate would have on someone from that era. Yes, aphrodisiacs don't typically work but in an era where people are not routinely exposed to sugar in any form (the only possible source would be honey), something like a chocolate candy would be very simulating, especially if she added another CNS stimulant like caffeine. It wouldn't directly lead to sexual excitement but combined with the proper mood it could probably steer things that way. I often wonder just how addictive something we take for granted, like a Coca-Cola, would be to someone who ate a diet of rice and seafood with minimal spices, their entire life.
Not to mention that in the modern world, even infants are exposed to high levels of sugar and everything else through the mother's breast milk.
We would have high tolerance to things since the day we were born.
totally agree. This is my personal anecdote but the first time i had coffee i remember i was awake for the entire day, active and aware for the whole time it was in effect. It was never the same after, but the first time your body experience something you'll have the most "authentic" reaction to it.
I hadn’t thought about that while watching, but I agree!
most chocolate that people are exposed to these days is barely chocolate to begin with
You deduct points from the show for being accurate to the timeframe, because we have ways to deal with something in modern times?
Also, silver reacts with a lot of metals and poisons so it was used for a lot of nobility over the years (you can see that by the silver coloration).
The tea is never meant as an anti poison measure, but to thin down the poison by hydrating, which is a practice that is nearly always correct.
10:20 In the manga and the LN Maomao mentioned specifically two cases with the prostitutes involving sleepwalking (one is real, one is a hoax), and how her foster father treated it, and YES, he prescribed them a lot of rest and some herbal sedatives, and that's all, since there really is no other way of treating sleepwalking in ANCIENT CHINA, for heaven's sake! What "benzodiazepines and antidepressants" are you talking about here? Valerian and similar plants is probably the best she could have mentioned here. And that is what exactly she was imlpying here - she cannot treat a concubine, since there is no real, working medicine, and those basic methods like "get more rest" were proved not working already. And if she would say "yes, there is a method", then the next order would be "then treat her", with the possibility of losing her head for failing to do so. Deducting 8% for the show being accurate here? Seriously?
Gotta disagree with ya doc. Her treatment of the concubine with tea was more for hydration and helping build strength. Sub title version actually had it as rice water because it was the only thing her weakened body could hold down. The sauna was to help sweat some of the skin contact toxins out, a common method in those days and in many cultures, and sweating is a form the body naturally uses to expel some toxins from it. Also, what's with the point system?! Major point deductions for wrong, but barley any for right? Heck, some you gave no points!
(I have a feeling that the grading was planned to arbitrarily get to a A- grade)
Silver turns black when it comes into contact with certain chemicals/poisoning. Because of this royalty and high ranked people would eat with silver plates and cups
21:00 the full context of this one is not over-indulging alcohol but over-consuming salt that lead to death, and the man in question lost his taste for salt which cause him to not realize how much salt was mixed in his alcohol.
Yep, with the current localizing drama going on and now this eng dub with A LOT of incorrections (not counting the bottom line quality voice acting), after watching sub i'm mad knowing this dub exist
I heard jinshi voice in dub and imagined a man in his late 20s or 30s. Not a late teen/young adult
Simply, i cringed and died
HELP
GOASHUN AND JINSHI SOOUND THE SAME AGE😭😭😭
Also, Moamoa sounded like a side character woman in her late 30s and has nothing in life anymore...
yeah the dub is terrible
you are wrong about her action to sleep walking, what you talked about is MODERN treatments for it, at the time of the story none of what you said would have been know or available, making her responce correct.
Doc, doc, doc , doc... she was only saying that they don't have a medical cure for sleepwalking in her times. Do you really know if they had smth like that in that day and age?
No?
Then please raise her score. Bad Doc picking on such a cutie you should be ashamed. 🤣
P.S Love your videos as always, good to have you back, can't wait for your next video
She didn't want to cure concubine with drinking tea doc, it was only smth to help flush the poison out (especially in those old days ), just like massage isn't smth that will cure Chronic Low-Back pain but will certainly help.
I give Apothicary some leeway in the fact medicine at the time isn't as advanced as now. While she did use some techniques not known then, stuff like sleepwalking wasn't as studied, and most would have attempted medicines we know now don't work. Same with the tea and hot bath. They knew it had effect, but not why or how well.
Actually a few people have been able to take certain types of poisonous substances and not even feel one thing. It’s rare and not studied all that much but it’s believed that a very powerful poison could cancel a weaker one creating some sort of immunity.
I feel it’d be more fair to rate her based on the medical knowledge of her time rather than your modern medical knowledge. But I also understand that’d probably be tedious, so I don’t blame you for not doing it. 😂
I would like to recommend you to use version with subtitles. Dub one is less accurate with Maomao`s medical terminology and treatment
I think aristocrats used silverware specifically because of silver's tendency to react with a wide array of substances. Silver was also thought to be a substance with holy or perhaps even divine properties, hence being deadly to mythical monsters like werewolves and (at least in some depictions) vampires. If I'm not mistaken, oxidized silver is black or at least a very dark gray. I wouldn't be surprised if people of the time saw the sickly discoloration of oxidized silver as this pure substance being tainted by the ill intent of whoever added the poison to the food that caused the discoloration.
I think the tea thing was just about making her drink as much as possible, and thus pee as much as possible, which would remove some of the poison. It's just better than plain water
Keeping your scoring within the bounds of medical treatment available when Mao is working would be more fair and accurate. A few people have mentioned methods that you debunked that work to identify certain popular poisons of the time. Keep modern medicine out of your comparisons with ancient medicine. I am sure that when you keep your evaluation in context and within the boundaries of the story’s knowledge of medicine, your scores will be quite different.
Since I see this evaluation as a modern versus 19th century medicine, it is definite: Mao would be in jail if she were practicing today. But she isn’t so I think she did well on the score.
Thank you for the video!
Note: some of Maomao's treatments are based on traditional chinese medicine. They didn't really have modern methods and medicines back when, so the general trreatment for foreign substances in the body is to encourage expellation via toilet activity, vomitting and sweating, in the belief that the body will eventually expel the toxins on its own; as long as there's plenty of fluids, it *should* work, only question is if it worked fast enough. Maomao's treatment of Lihua is correct for its period, which does not have easy access to any ingestibles we're used to because they do not have the capability of manufacturing them.
7:48 silver will ternish with in contact with arsenic or any sulfur based molecules.
I'm a pharma student and yeah, some of us do experiment things on ourselves to a certain point out of curiosity, but it's unusual and frowned upon since it's pretty unnecessary. It's mostly relatively harmless things that won't mess you up in the long term.
for the sleep walking yes we may have one right now but this is the 17th century chances are historically speaking they have none of that
the doctor might need to get fact checked tbh legit we need a recount
Guys he's not criticizing Mao Mao's knowledge or characters, he is simply debunking things that fans might be curious about, if it actually applies in real life too.
Finally someone gets it
Our pharmacies are literally called Apotek which means apothecary I had never considered people might not know because of the language changed over time
We called an apothecary as 'apoteker' in Indonesian (it referred to the person instead of the place)
The original title in japanese is the pharmacist monologue so it refers to the person instead of the place.
Apothecaries in the modern sense actually refer to Chinese medicine stores that dispense traditional medicines. It’s a bit rare in Europe but somewhat common in the states. The Chinese community still uses these places as often the older generation likes them quite a bit and don’t fully trust western medicine. I take the occasional trip to one myself and yeah it’s pretty good. I mean you do clear your nose a lot quicker as the smell of menthol lingers in the air. I take traditional Chinese in combination with standard western medicine as a way to hedge my bets a little. At something has to work you know.
Im confused about your point in developing resistance to poisons....those addicted to drugs or alcohol often require higher higher dosages to get the same effect how is this not the body being more resistant?
Same. Was'nt there a King who helped the Study about Poisons by consuming them? Overly sarcastic productions did a Video about him. He himself build up a resistence against them, which kinda backfired. Becouse when Alexander the Great invaded his Kingdom he wanted to commit suicide via Poison.
They also would put a silver pin into the food to test for poison. Apparently sulfur compounds cause silver to turn black and arsenic contains sulfur.
TBF, Mau Mau not knowing of a treatment for sleepwalking likely comes down to when such treatments became available, is it not accurate to the time period it was depicted in?
About having resistance or immunity to poison, do the African Tribes who hunts for bees count?
Those tribesmen were getting sting while eating the honey and they don't even react.
This is a good example of adaptation rather than immunity.
Immunity has a very specific meaning when used in the medical field
@@docoffcall This is more of a failing of the English dub, in the manga she does refer to it as a tolerance and not an immunity.
Some stuff like the sleepwalking seems pretty intentionally incorrect or incomplete because of the time period.
The series isn't set in modern times, so the characters wouldn't have access to a lot of knowledge we have today.
I wanted to mention that Maomao didn't say that there wasn't a treatment for sleepwalking. She said that she didn't know and that it was outside of her expertise. Another commenter already beat me to it, but the author of The Apothecary Diaries used medical knowledge thought to be true during the 19th century, so it's explicitly not meant to be accurate to modern medical knowledge. If it were, that would break the mood of the time period the novel (and now anime) is set in. I'm actually still surprised by how much the anime got right, though. Or at least right for the time period.
I'd love to see you react to 'Parallel World Pharmacy'. It's a much less known anime, but it's an isekai about a modern day pharmacologist gets, well, isekaied into a medieval world. So it would be cool to see how the medical practiced he brings in holds up to actual modern medical science, since he's supposed to be from a modern time period.
At ~ 7:00, you say that you can't develop actual resistance to toxins, but that isn't strictly true. Antibodies have been shown to be at least *mildly* effective against toxins of many kinds. Antibodies are, of course, created by B cells which can be activated more quickly and more effectively after initial exposure, which is the mechanism by which both snake anti-venoms and vaccines work. I also, of course, recommend that you don't actually attempt to develop an immunity to any kind of poison through exposure, as that's a terrible idea.
To be fair, he did say you can’t build natural immunity to it not tolerance or resistance. Immunity is different.
@11:00 I'm not sure ancient china had anti-depression or benzo...bezo.... sorry the other molecule you mentioned.
Do those people so call doc themselves know this anime is more like detective anime instead of medical related??
Man I got whiplash from hearing the dub. It's a sin to squander an Aoi Yuki performance.
Dead bodies that have bruise patterns are quickly investigated and sometimes you even see handprints on faces. This bruising only lasts about six hours and medical examiners must take photos to determine cause and whether to pass it to the police.
There is one rare type of Tobacco that doesn’t cause the same symptoms like regular tobacco. It’s called giant tobacco or tobacco gianta. Very rare outside the US and Mexico. This rare tobacco gives a person an uncontrollable fever which just keeps rising and has to be cooled via water or cold dunking, it also gives very vivid hallucinations that create a very violent state of being. But in essence it’s just nicotine Poisoning but much more pronounced and powerful. It’s why this exact plant is so strictly regulated as it’s still considered a type two drug but can go into a class 1 in a heartbeat. If the symptoms appear then the patient somehow ingested it in some form and you have to calm them down then administer nicotine poisoning protocol just over a longer time and a bit more medication with a dose of calming agents to put them out before they hurt themselves.
Huh she didn't say anything about detoxification through tea. It was just said to increase urination. Isn't more frequent urination good to make your kidneys work and flush out in general?
Will you ever make a Medical Bill series for Jujutsu Kaisen characters?
I'm curious whether Itadori or Megumi would have the higher bill by now
Yeah this would be cool
Which character would you like me to look at from JJK
@@docoffcall Both Itadori and Megumi in a comparison vid, like the one you did for the fight between Spec and Hanayama
Both went through the ringer in the past two seasons, but bear in mind that Itadori has strong poison resistance, not like it'll cover the emotional damage.
Why is the counter not increasing 😂 24:23
Also, It's possible to develop immunity to some poisons but not all (mainly specific non biological poisons). However it's extremely dangerous and a lot of it depends on having good genetics.
Its impoossible to have an immunity against poisons
An Immunity means you are impervious to something, meaning that no matter the dose you will remain unaffected but thats simply unrealistic. A large enough dose will kill you thats why people can Overdose and die
You can however develop a Tolerance to something, meaning that you can handle a larger dose than the average Joe but that doesnt mean youre invincible to that poison
For example Alcohol is the most common poison known to man. Alcohol can be metabolized by the human body (meaning you can naturaly neutralize it) and frequent exposure to small doses of Alcohol can help you build up Tolerance to its effects and most modern humans have varying degree of Tolerance to it but there isnt a single human immune to it a large enough dose will always be fatal them
My question about getting natural immunity to toxins is, why are homeless people rarely ever affected when they eat damn near moldy or rotten food? I've always wondered this. If I forget to wash my hands before I eat, I run the risk of getting constipated, but they are usually fine.
I wanted to add to this.
Because Maomao exposed herself to lots of toxins when young, her body had the time to develop subtle immunity to things that would normally kill her.
She only used small amounts of said toxins at a time, so it allowed her develop antibodies against multiple types of poison.
I used to spend most of my infancy in a hospital so I was exposed to lots of viruses and ailments. Overtime, this let my immune system develop antibodies to either omit a virus from effecting me entirely, or sped up the recovery process.
Maomao may not entirely be immune to poison, but she perhaps would have the immune system to fight off small amounts.
I'm surprised at the difference in delivery between the Japanese voice actor and the English. The Japanese one seems (to me at least) to be far superior at this role. Changes in the script as well... for example in the Japanese version I recall Maomao saying she built up resistance, not immunity.
Thank god I'm watching it with subtitles...the english dub sounds so weird
Funny that they reference Sherlock Holmes, the man that inspired Sherlock was Joseph Bell, Sir Arthur's Boss and medic mentor.
The talk about building an immunity to poison is a translation error.
In the source material she talked about building a tolerance, never an immunity. Just as she said with the allergy.
Maomao is the goat of the series!
You should use the subtitled version. Dubs for reasons of syncing time aren't accurate. Maomao doesn't say she's giving her tea as in Camelia sinensis but as in a medicinal herbal tea. It's said in the original Japanese & shows up in the subtitle.
the most famous medical version of sherlock holmes is of course, House MD
finally the video i was waiting for
Between 12:42 and 13:21
It was said later that she justmade up the bath treatment and just wanted the bath made so I think it needs to be reviewed
White lead has long been loved for creating a really great shade of white that is superior to most other solutions. Not just popular in makeup, painters used it for centuries and still do, though it's more restricted these days. White lead paints can only be sold in small quantities in most countries now but painters still use it.
Great breakdown as always! really enjoyed your insights and I definitely learned a few things.
I've been sitting on this show... Now I'll go and watch it
I'm sure benzoyl didn't exist back then lmao
Thank you for the video.
In Chapter 63, it is revealed that Jinshi is not a eunuch.(he was using a Tea to chemically castraied himself it was not the permit type of Eunuchisum)
Happy new year Man.😁👍.
Love your vids but do more fighting ones or more exciting animes please?(still great video)
Will you take a look at how animals such as apes, birds, or reptiles handle injuries?
Kemon doctor you think sleepwalking analysis back then was as advance as now??plus she is just an apothecary not a psych doctor.. Maomao not knowing any cure about it is historically accurate
Not all teas have caffeine :-p
To be fair on sleepwalking, maybe the medicine wasn't discovered by then.
Why do you sound like a minecraft youtuber doing 100 days challenge 😂❤
I need my ears checked please, this is english dub, haha.
I couldn’t even get past the 4 mins mark because this doc rather use the dub version for his analysis instead of the original version with English subtitles.
Came to a point I’m not sure which was worse: the voice acting, the English translation quality, or the out of context analysis using current medical standards to critique medical practices of the past in the East at that.
You didn't bother to watch... only seen some cuts, I guess... first of all, it isn't and never was medically accurate per current knowledge, but rather reflects beliefs and practices of that era, and additionaly censored/or knowingly misrepresenting (chocolate was presented as aphrodisiac) to not give people ideas... just like Breaking Bad doesn't teach actual meth production, and fight scenes in movies doesn't show actual effective combat techniques.
It's of course ok to give current day advices, but it would be better to not miss what actually was happening in anime... there was more going on with Mao Mao therapies, not just single gestures like tea or steambath... sleepwalking advice was ok I guess, but sleepwalking in anime was faked by "patient" anyway.
Nice breakdown, but there's 1 point that I'm not sure if I would agree and 1(or 2?) point that I disagree.
I'm not sure if I agree with the "no medication for sleepwalking being not accurate". While we have medication for sleepwalking rn, IDK if there's medication for it at the time period this anime base on. It might be accurate bc people at that time haven't found the way to cure sleepwalking.
I disagree with your view on how Maomao treated Li Hua. Firstly, you view the use of tea and sauna to treat her separately, even tho they're treatments for 1 case. Maomao gave her a diuretic tea and sauna to push out the poison that is in her body for a long time(Just imagine how long had she used that poisonous powder before she get treated.).
:)
Does anyone else get Dr.Stone vibes off this anime?
Unexpected doctor offcall watching non shounen series ,
19:22
what year is Apothecary diaries set? Because they couldn't have had Tobacco in China if this is set before the European discovery of the New World.
I think it's after europe? Because there are some ingredients she got from foreign country when she makes chocolate
I remember tobacco being mentioned in one episode
I think it's supposed to be in the equivalent of the late Ming dynasty, so somewhere in the 1500s-1600s. Late enough for there to be trade with things from the Americas.
It does say that cacao is an import, but a very expensive one.
If nothing else, this definitely makes me glad I'm not watching the English dub.
I really do hate that "building up an immunity to poisons" cliche, and I can't believe this anime did it too.
To be fair, I'm pretty sure she describes it as a "tolerance" in the sub, rather than immunity, more in line with what is actually possible. It is a tired trope, but I think they use it decently well in this series as a relatively realistic "superpower" to enable Maomao to be as preternaturally knowledgeable about poisons as she is.
But, that's just my two-cents. lol
It's not an immunity. If she was, then she wouldn't be on the ground writhing in pain or having to make herself puke the poison after swallowing it, and so on.
Yeah, pretty much as others said. That's another case of dub script screwing up what is said. In both translations of manga and anime's sub it's translated as "tolerance to poisons". Let's not forget one of reasons Maomao loves testing poisons is the feeling of complete body feeling numb / paralized.
@@WhatKindOfNameNow Yeah, tolerance is a better word.
While you can't really build immunity or really any kind of tollerance to inorganic poisons like lead, mercury, arsenic and so on, to my knowledge animal venom is a different story and you can for example gradually become immune to a snake's venom by injecting yourself with small doses.
The problem is, every animal and sub-species have different venoms so slowly building your resistance to cobras' venom won't save you from the black mamba's one.
To be covered against all venoms would require a person to inject themselves with thousand of different venoms every day.
Doc would say to watch the Japanese with english subs. As much more accurate then the english dub version. plus all the actors don't sound the same (female and males.)
Holy crap the dub is horrible
I hate the dub version, the voices are so cringe. 🤮
Can't take the dub
Ughh, Uggh, I'm 20 seconds in and I've just bounced off the american translation! Can't watch this....
Bro really just called out Best Girl Maomao for not knowing about modern medicine and practices in ANCIENT CHINA 💀