How to find percent of the bases in DNA (Chargaff's rule)
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- Опубліковано 19 сер 2024
- Chargaff's rules state that DNA from any cell of all organisms should have a 1:1 ratio (base Pair Rule) of pyrimidine and purine bases and, more specifically, that the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine.
Chargaff rule: The rule that in DNA there is always equality in quantity between the bases A and T and between the bases G and C. (A is adenine, T is thymine, G is guanine, and C is cytosine.) Named for the great Austrian-American biochemist Erwin Chargaff (1905-2002) at Columbia University who discovered this rule. Also known as Chargaff's ratios. Chargaff later said: "This observation of complementarity, later called Chargaff's ratios, was essential to the solution of DNA's structure. In hindsight, the complementary pairing of the nucleotides powerfully suggested that a DNA molecule could break into two parts. Only complementary bases could form bonds and line up in place in a new DNA strand."
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I don't understand how did you get the percentages?
four bases is equal to 100 %
And 100 - 60 = 4o
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same here *crying*
Medical student studying chargaff's rule ? 😂
We do it in 12th
This was very helpful thank you!!
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What is the percentage of DNA in our body?
The percentage of DNA in our body varies depending on the cell type and the stage of development. In general, all nucleated cells in our body contain the same complete set of DNA, which is approximately 3 billion base pairs long in humans.
However, not all of this DNA is actively transcribed or translated into functional proteins. In fact, the majority of our DNA is thought to consist of non-coding regions, which do not directly encode proteins but may still play important regulatory roles in gene expression and other cellular processes.
Estimates of the proportion of functional DNA in the human genome vary widely, but some studies have suggested that only about 1-2% of the genome actually codes for protein-coding genes. Other estimates have suggested that up to 80% of the genome may be transcribed into RNA, although much of this RNA may not necessarily have a direct functional role.
It is difficult to give a definitive percentage of DNA in our body that is functional or non-functional, as our understanding of the complex regulatory and functional roles of DNA is still evolving.
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