Once again the man delivers! You certainly put a magnifying glass and expound on it where textbooks and standard learning tools just gloss over it. Thank you very much Ninja Nerd
A Young man, who really knows his subject, I am a therapist, and live to study this stuff, but, this guy is incredible, what a brain he has, live people like him who know their subject.
Zach you are making me go to medical school..... as a genomics scientist and ever wanting to learn, I am so happy to have found your incredible lectures!!! Simply the best!
How many times are you going to win the only heart I have. This guy is really a god gift for medical students around the globe. Huge Respect and love from Germany :)
I just survived thyroid storm, I'm still at home recovering from it, after being the hospital for a long time... enjoying watching your videos so I can understand this better.. I had no idea I even had a overactive thyroid and I go to docs , they just never tested it..
This video was AMAZING. My professor's notes are so scattered, we never know where he stops one section and begins the next. THANK YOU for putting this together so well!!!
You are a life saver! The way my lecturers explained it never seemed to make sense to me. The way you go through the whole process step by step is super helpful. Now I now how to T4 and T3 are synthesised and I'm confident for my exam. Thank you!
This is pure gold - Read my physiology book and didn´t understand much - untill i watched this video. Now the books is easily understood! Thank you very much - and please - please - never stop making these videos!
I’m relatively new on this channel and I’m finding it a terrific resource in learning the things I need to know. I have Panhypopituitarism, have had it for over twenty years but I’m still learning all of the factors involved in maintaining one’s life when one’s pituitary gland is basically nonexistent. Thank you so much for helping me to understand as much as possible regarding my medical plight! Best regards from Kathryn Featherston 😊🎓☺️🧠
Dear Dr Zach, your teaching styles are so awesome! I’d already wacthed entire of Biochemistry, Microbiology, İmmunology, Cell Biology sections, and currently on in Physology. You and your team doing a great job! Keep going on!
The numbered recap at the end was super helpful in organizing the main bullet points. Thanks for all your amazing work! Because of you, medical school isn't just about memorizing anymore. You're the man! Also I saw you wear some UH gear in one of your videos, go Warriors!!
oh my god, you are AMAZING. I'm new to your channel. I am currently studying endocrinology for my physiology class, and you are a lifesaver! My prof's notes are so vague, and he talks so fast during lectures that it is hard to write down all the extra information he says to clarify the notes. But your videos, really help to fill in those missing gaps that are in the notes my prof posted. I am officially not scared of my final exam anymore. I subscribed. Thank you so much, you have made my day!!
This video is so amazing!! You go into all the wonderful details without making it overwhelming. I’m currently reviewing for my vet school finals and this was pure perfection.
Literally every topic I start I come here for your video’s, reading alone I can’t absorb but I watch your videos and it all clicks into place, thank you for helping me pass my degree, I don’t think I could do it without you💓
Thank you for these videos. You don't know how many times your videos actually saved me from flunking my previous semester, I have seen your videos from biochemistry up to here. Thank you for your hard work! Sincerely, A Struggling Med Student.
~You are amazing...getting your point across in the simplest way possible....YOU should or maybe you already are an instructor....thank you sooooo-much for everything young man. Teaching is your gift.
My mind is blown on how scientists have actually studied this not to mention the 500 kazillion other things in our body. You are a really intelligent guy. Geesh
Sir, I am a fan of your teaching...You explain complex things so simply it's amazing...Thanks for making these videos, please make more of these videos.
I have a small correction for a very small mistake in the video After the cleavage of T4 and T3 from thyroglobulin, T4 and T3 won't have a vesicle around them, because they actually lipid soluble, so they will just diffuse from the thyroglobulin vesicle (which is made primarily from lipid) to the cytosol, then they will diffuse also through the cell membrane to the bloodstream. Thanks so much for your videos they are really helpful.
@ Ninja Nerd Science, during coupling process of iodothyronine residues @ 16:15.. MIT+DIT is a reverse T3 of which is biologically inactive. The only Active T3 (Triiodothyronine) coupling residues is DIT+MIT. Thank You.
![Thyroid Hormone Synthesis: Step-By-Step Pathway [Physiology Explained]](/img/n.gif)
18 dislikes are the school professors who are losing students to this guy... Your work is incredible man.
Fax😏
🤣🤣
🤣🤣
Fact🤣🤣
Totally agree 🤣🤣🤣🤣 koz I don't watch anyone else...not even my own professors
Your ability to read complicated info, understand it, remember it and then explain it so well is beyond imaginable!!!! Amazing
when he explained t3 and t4 my head exploded. I literally yelled. I think all this studying is getting to me.
Me too!
You are right, that was my first time to understand that part of thyroid physiology. Wonderful Teacher!!!
you've helped so many med students become doctors
Soo damn truee!!!!!!!
Nurses too 😂🎉
It's true
PAs too!
Pharmacist too!
Once again the man delivers! You certainly put a magnifying glass and expound on it where textbooks and standard learning tools just gloss over it. Thank you very much Ninja Nerd
+Reynaldo PersonalEmail we are so happy to help! I am so glad that these videos are helping! It is our goal to help in anyway possible!
Endocrinology used to be my least favorite part of physiology until I watched your videos. Thank you for everything!!
Do you know if a thyroid issue could be mistaken as diabetes? Type1.. some of the symptoms seem to be about the same for both.
OMG SAME! After learning from these, I topped my class
@@NanditaJali i want to quit
@@aryan7767 you wanna talk about it?
@@NanditaJali im so sorry for concerning you. no its my own laziness pls ignore me haha
Table of Contents
0:00 Intro - Hypothalamic-Hypophyseal System.
3:46 - TSH Effects & Thyroglobulin Synthesis.
7:30 - Thyroglobulin and Iodide/Iodine.
12:10 - Iodination Process.
14:18 - Formation of T4 and T3.
19:26 - Transportation of thyroid hormones.
20:50 - Recap.
Great
As in a book?
not all herroes wear capes
Thanks
THANKS!!!!!!!!!!!!!!!
please please do this for all his videos!!!
A Young man, who really knows his subject, I am a therapist, and live to study this stuff, but, this guy is incredible, what a brain he has, live people like him who know their subject.
Sorry for spelling, phone.
Zach you are making me go to medical school..... as a genomics scientist and ever wanting to learn, I am so happy to have found your incredible lectures!!!
Simply the best!
honestly can't emphasize enough how much I appreciate your work
Your videos are PHENOMENAL! You've got a great teaching style, keep the videos coming!
How many times are you going to win the only heart I have. This guy is really a god gift for medical students around the globe. Huge Respect and love from Germany :)
Seriously, you do not understand how many times you've saved me and I'm only halfway through my degree....
L
Thank you so much for taking dry, complicated subjects and bringing them to life so that they are understandable! I'm so glad I found your channel!
You are seriously the BEST to ever exist and to ever TEACH, not one university professor compares. Lots of love!!!!!🙌🏽
Much love and respect to you. Thank you. I feel like crying right now because you explained it so well!
"T peroxidase kicks iodine so hard it knocks an electron out of him" lol that's a good way to remember it
He is an amazing teacher genius
Lmao yesss
Dude, thats literally the golden commentary ever
🤣🤣🤣
😂😂😂😂😂😂😂
I just survived thyroid storm, I'm still at home recovering from it, after being the hospital for a long time... enjoying watching your videos so I can understand this better.. I had no idea I even had a overactive thyroid and I go to docs , they just never tested it..
My sir taught me this 3 times but still i used to forget this concept and you taught me only once and now i remember forever 🙏 Thankyou
Sir, you deserve a medal of honor. I'm screaming thank you!!!!
my GOD!!you have no idea how much i love you! you always save my grades!! good job and i hope you never stop teaching us!!
This video was AMAZING. My professor's notes are so scattered, we never know where he stops one section and begins the next. THANK YOU for putting this together so well!!!
trueeeeee
The most amazing UA-cam video I've seen all year. Thankyou for producing it. It's most helpful in explaining and incredibly complex.
You are a life saver! The way my lecturers explained it never seemed to make sense to me. The way you go through the whole process step by step is super helpful. Now I now how to T4 and T3 are synthesised and I'm confident for my exam. Thank you!
This is pure gold - Read my physiology book and didn´t understand much - untill i watched this video. Now the books is easily understood!
Thank you very much - and please - please - never stop making these videos!
I’m relatively new on this channel and I’m finding it a terrific resource in learning the things I need to know. I have Panhypopituitarism, have had it for over twenty years but I’m still learning all of the factors involved in maintaining one’s life when one’s pituitary gland is basically nonexistent. Thank you so much for helping me to understand as much as possible regarding my medical plight! Best regards from Kathryn Featherston 😊🎓☺️🧠
Dear Dr Zach, your teaching styles are so awesome! I’d already wacthed entire of Biochemistry, Microbiology, İmmunology, Cell Biology sections, and currently on in Physology. You and your team doing a great job! Keep going on!
This guy is just unique in his explanations. He is a professor of the age! No match yet!!
You seriously deserve so much more credit then you are given! I love your videos please don't stop making them lol
This man explained his topic passionately with humility. Thank you so much for creating good techniques. 👏
The numbered recap at the end was super helpful in organizing the main bullet points. Thanks for all your amazing work! Because of you, medical school isn't just about memorizing anymore. You're the man! Also I saw you wear some UH gear in one of your videos, go Warriors!!
oh my god, you are AMAZING. I'm new to your channel. I am currently studying endocrinology for my physiology class, and you are a lifesaver! My prof's notes are so vague, and he talks so fast during lectures that it is hard to write down all the extra information he says to clarify the notes. But your videos, really help to fill in those missing gaps that are in the notes my prof posted. I am officially not scared of my final exam anymore. I subscribed. Thank you so much, you have made my day!!
This video is so amazing!! You go into all the wonderful details without making it overwhelming. I’m currently reviewing for my vet school finals and this was pure perfection.
Nerd ninja you are God to Indian medical students
Big love from India !!
I personally want to meet you some day sir
I guess 10 millions gods werent enough for yall
@@med8615 yet following any gods would give the same vision! : Do justice nd u'll get the same !
I get it you apreciate him hes really good at wht he does but he doesnt replace god and he is not a god he is just human
God is there with in every creature
Usama N
A man with a name OSAMA shouldn’t talk about god atleast😂
Literally every topic I start I come here for your video’s, reading alone I can’t absorb but I watch your videos and it all clicks into place, thank you for helping me pass my degree, I don’t think I could do it without you💓
15:33 I literally gasped 😲
Understanding T3 & T4 🤓
Thank you ☺
Me too! Not where I was expecting things to go. So cool!!
When you came to the coupling part, I died, this is gold. THANK YOU!
BIG thanks from iraq 🇮🇶 you really help me in my post graduate medical career , keep going on dear and may God bless you dear.
انشالله تخرجتي ؟
thank you for sticking through the whole process of making this video
you are so power brooooooo!!! this video is very very helpful ! i'm so glad that i found it .
Thank you so much! And if you could share with friends that would be appreciated!
I have no words how to appreciate your effort.Really mind blowing Sir.Thank You so Much.
You are the best medicine teacher in the world! I'm a med student from China. You are my superman!!!🥰😍😍
Pharmacy student here, great video thanks for the help Ninja Nerds.
You make learning so fun, you make learning all those steps not hard to love
You are my BEST teacher. The greatest ever. Thank you
currently in an accelerated program and your 30 minute lesson is 10000000x better than the doctor's 3 hr lecture.
Exactly
Every time I watch a video of this guy, I thank God for making me learn English (I'm from Brazil)
Nerd Ninja you're absolutely a blessing to Med students . Fan here from Papua New Guinea 🇵🇬
You deserve an award for helping many medical students 🙌🏻 excellent
You have alot in the ball ...I can't get over how much your vedioes are helping me ...
props for the camera guy who always follows your movements! love u guys
so good thank you ....saving my life as a pharmacy student.. honestly professors do not even explain they just sent a crap ppt and called it a day
Thank you for these videos. You don't know how many times your videos actually saved me from flunking my previous semester, I have seen your videos from biochemistry up to here. Thank you for your hard work!
Sincerely,
A Struggling Med Student.
This makes studying Pharmacology easy! I'm currently cramming for a big presentation and don't know what I would do without your videos.
~You are amazing...getting your point across in the simplest way possible....YOU should or maybe you already are an instructor....thank you sooooo-much for everything young man. Teaching is your gift.
i cannot believe how amazing this is! Thank you Sir! Incredible work!!
Thanks Zach,u are helping millions of mbbs students to get graduated easily.
Tanks from algeria eventhough our médical studies are done with french language
Your lessons are much better realy you are a great men
I have Panhypopituitarism. I've always seen T4 on my bloodwork but never knew what it really meant. This video was incredibly informative!
i just understood it within 10 min after watching THIS my whole conception got cleared
you made that complicated mechanism perfectly EASY! Thank you
Sir, you my respect. I hope your personal life and character are as excellent as your teaching ability and knowledge. Good work
I repeated the video twice to stuck the information ,huge thinks for your effort 💜💜الله يجزاك خيررر
For those wondering what the Transcription Factor protein is at 5:04 , its Thyroid Specific Transcription Factor-1 (TTF-1)
You are certainly teh best teacher of Biology... I always get here when something irks :) God Bless You
Thank you so much sir........you did help me to score the highest marks ❤️❤️❤️❤️
If not you some of us would have really failed to become good doctors, you really doing a great job!!!
What an amazing lecture! Thank you so much Ninja Nerd ❤ You help me a lot
The smile that lit up my face when it all made sense. What a beautiful romance between T3 & T4, I guess the T.P.O is the matchmaker.
My mind is blown on how scientists have actually studied this not to mention the 500 kazillion other things in our body. You are a really intelligent guy. Geesh
I just discover this channel and I am so grateful for this quality content and those brilliant mind ! Thank you !
This was very satisfying to watch to re-run-through in a more focused break-down
I love your videos!! I appreciate them so much!! Thank you so much !! YOU ARE SAVING MY LIFE !!
This channel is a treasure
Sir, I am a fan of your teaching...You explain complex things so simply it's amazing...Thanks for making these videos, please make more of these videos.
I can listen to these discussions all day even i don't remember anything
Wow, you are amazingly smart. Thank you for teaching this. You make it so much easier to understand
I wish my textbooks were this clear and concise
My continued survival of med school is dependent on these videos. Thank you
Absolutely awesome man... Huge respect for you man the way you teach is just amazing..... Lots of love to you from India🇮🇳
I am starting to love endocrinology because of you. Thank you so much!!!!
Thank You Zach! Thank You Ninja Nerd Science!
Don't stop teaching please huhu I love your methods of putting things to perspective. Superb. Thank you
I feel like, I am in heaven when I am listening to your lectures
Man I wish UA-cam and this guy was available when I went to nursing school in 2011…
was so confused by my lectures but this is so clear and I'm actually interested!! thank you so much cant wait to watch more in the future!
I have a small correction for a very small mistake in the video
After the cleavage of T4 and T3 from thyroglobulin, T4 and T3 won't have a vesicle around them, because they actually lipid soluble, so they will just diffuse from the thyroglobulin vesicle (which is made primarily from lipid) to the cytosol, then they will diffuse also through the cell membrane to the bloodstream.
Thanks so much for your videos they are really helpful.
Best Channel for physiology ever❤
My students have told me about your lectures today. Wow this is inspiring!
Is it possible to upload a photo of the board with all of the drawings? you guys are amazing, I appreciate all of the work you put
You are really the coolest teacher ever. Thanks for making medicine so much fun. So much love and best wishes.
Your explanation is incredible man...I need you in my college😢 .. all respect to you❤❤
Bro is literally gods gift to medicine
Thank you so much for these details
@ Ninja Nerd Science, during coupling process of iodothyronine residues @ 16:15.. MIT+DIT is a reverse T3 of which is biologically inactive. The only Active T3 (Triiodothyronine) coupling residues is DIT+MIT. Thank You.
DIT can bind to MIT or DIT, but can you get MIT binding with another MIT? T2 hormone?
You make complicated topics so easy...thank you...
You are a true KING of biochemistry, thanks so much !!! you make med school more fun ;-)
The french guy- TPO is my new favorite
excellent video...u forgot to mention endocytosis of colloid is done by megalin protien...
That's a great experience! Feels like really synthesizing such hormone! 😄💫