How we can finally win the fight against aging | Aubrey De Grey | TEDxMünchen
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- Опубліковано 21 лип 2024
- For more information on Aubrey de Grey, please visit our website www.tedxmuenchen.de
Dr. Aubrey de Grey is a biomedical gerontologist based Mountain View, California, USA, and is the Chief Science Officer of SENS Research Foundation, a California-based 501(c)(3) biomedical research charity that performs and funds laboratory research dedicated to combating the aging process. He is also Editor-in-Chief of Rejuvenation Research, the world’s highest-impact peer-reviewed journal focused on intervention in aging. He received his BA in computer science and Ph.D. in biology from the University of Cambridge. His research interests encompass the characterisation of all the accumulating and eventually pathogenic molecular and cellular side-effects of metabolism (“damage”) that constitute mammalian aging and the design of interventions to repair and/or obviate that damage.
Twitter: @aubreydegrey
This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at ted.com/tedx
You go through life, gather knowledgeable and wisdom, then you die. Living longer, as a vigorous psychologically young person, will advance civilization exponentially. Go Aubrey! Support SENS research and make your governments support this research.
He'd need 1000s of years to have a grain of wisdom, judging by his current wisdom ...
Prirodoljub Care to elaborate?
@@texmex321 someone prolly just pissed in his cornflakes lol
Imagine if 100k people a day didn't age and die? We would overpopulate in weeks
@@anthonynicholson5523 Improvements never happen overnight. Population problems are easy in comparison. See Hans Rosling.
Best of luck to you and every researcher working on this.
There luck is our luck
It's not research, it's capitalism. They create fictional stories and you create the market buying their useless stuff and software solving not any relevant problem in this direction.
Wow, someone is already working on this problem!
I'm really glad that people are finally starting to concentrate on possible solutions to the most important problem of humanity - death.
Thank you for your work, folks from SENS!
The most important problem of humanity is gluttony, greed, stupidity, or whatever you'd like to call it. Start solving it by yourself, on yourself, and let other sheep handle theirs. What does SENS stand for; Subhuman Entities with No Sense?
@@postconsolepeasant6538 Your naivety is heartbreaking ... Where on earth do you find such ridiculous ideas; do you actually believe that mortality/aging is preventing 'people' from giving a care for the world?
@@mujotomi gluttony, greed, and stupidity are apart of being human you can't take those away without taking personality away. Mortality is actually a problem we can solve.
@@mujotomi For example people think that they will be dead when climate changes dramatically
If ppl dont die overpopullation does
If he does it we destroy the world
it's the next step in evolution, to defeat aging side effects that is making us weak and sick, but it will require our free will and intellect, conscious about aging, unlike animals must lead to cure, animals are not even aware of aging and they can't do anything about it, but we can. So thank you everyone who support Aubrey and for donations.
To put it simply the human body is like a battery that needs to be recharged & grounded. This is what the Sumerians and Egyptians did to themselves to live so much longer . We have amazing lost ancient knowledge and we need back . At the moment our battery body will suffer a burn out right around 80-100 give or take. Our soul energy will leave the battery-vessel premature.
@@72marie I was thinking how everything loses it's working properties, batteries too, even recharable batteries lose their ability to recharge after longer time, magnets attraction also. So MAYBE that law of physics is that causes aging too. And if we find out what exactly it is, THEN we can make properties of young us to be rebuilt.
well! quality food and physical activity are great tools against aging but most people don't even care about it so maybe we should start with the basics
People are delusional.. they have to understand this
I saved 15 lives!
?
Raph....Aubrey said each dollar donated to SENS foundation saves 1 life, basically so Emanuele donated $15. :)
oh hey I saw your video on conways game of life I came from the link you put in the description
Aubrey De Grey stands on a bridge. Death trying to go through. Aubrey De Grey: "YOU SHALL NOT PAAAASS !!!!"
MrStarTraveler 😂
*You thall not path
😂 😂 😂 😂
50% of people do deserve to die but it is they who want to be immortal.
@@Pakistan-Icecream I think the news and social media tend to sheds the light on the worst of humanity making humanity look much worse than we actually are.
Let's instead spend billions for building stadiums since those are more important!
Anzor Aslanukov and Trumps walls 😞.
Anzor Aslanukov lol
Wylted, seems border security (at Mexico) will be important until there is UBI good enough in South America and basically the whole world.
Anzor Aslanukov ...this is a silly statement. The people making stadiums are not scientists ....or researchers. They can raise funding because a profit could be made. Banks don't give loans for futuristic research.
Extending life is about as important as reasons to live life.
Thank you Richard Heart Billionaire founder of Hex for raising 27 million dollars of donation to the SENS Foundation in 5 Days!
Much love Aubrey, it was so great to meet and take a photo with you at the Hex 2022 conference.
lets wish him success
And give him money so he succeeds
@@RationalAnimations Yes, just do that, you idiots who can't think even 1 step ahead.
It's a conspiracy..
@@mujotomi And the problems?
@@brianlam5847 What do you mean?
I think his research is the future. People don't realize that civilization is aging, with a rate of births that is getting smaller. At this time the working-age population is Germany is just 54%. With regenerative medicine can cannot only extend life but also keep the civilization going.
When Aubrey De Grey is in a room full of people disagreeing with him, he is the sane one.
This guy is out of his mind. It reminds me of the story of King Midas. Be careful what you wish for, you might find there is a curse that comes with it.
But then I would have to believe a lunatic like you ...
@DAILY OBSERVER Yes, 16 months, mentally, that is.
@@rickwyant Sometimes there is a thin line between madness and genius. The SENS labs have already had great successes in hard medical techniques that are beneficial to all.
@@rickwyant you can die when ur 90 I'll love living until 200. Enjoying my family
Powerful Gandalf de Grey!
We shall name him Aubrey De White when he succeeds. :P
Rather Radagast the Brown
Pretty sure I sold weed to this dude.
Pretty sure this dude sold me weed.
nope, this is the Radagast the Brown
Aubrey is a frigging genius.....
Recently he even made progress on a math problem that stood unaltered for 65 years. Try to search "Aubrey de Grey chromatic number of the plane" on Google.
Emanuele Ascani daamn he is so good
..... but just for idiots.
@@mujotomi You guys are insane, full of illusions, a simple word for you"bot"
@@Mr__mehta You can't even use singular, let alone realize that you are a robot, so don't patronize me and project your flaws on me. If anyone is insane, full of illusions, that would be Aubrey, the king of dwarfs and his dwarfs, one of them being you. A passing look at him -- and I believe at you, too -- reveals this truth. By the way, did you notice that you mimicked my statements? (A hint: insane, bot.)
Dr. Degrey, I have been reading about you in books about ageing for a long time now. I love the way you use high humor to engage your audience. Well done. You are a far cry from the stereotype of being a boring scientist. I wish you all the best in your research efforts.
Incredible man working on a really importance problem! So happy to see all the support in the comments :)
Sheep support doesn't count much, you know.
@1:42 Funny but so true, we all want to make a difference in people's lives even if we don't care much about the person next door. Crazy place, this world!
Don't be fooled, he only wants a recognition ... Yes, it's a crazy place -- for lunatics getting so much praise ...
He has now raised over 20 million dollars, it's happening
Aaaaand he has been cancelled now. We are all going to die!
Great talk, very interesting, thank you Aubrey De Grey!
That beard is legendary!
and you are so hot ...
That beard is immortal. All Aubrey de Grey needs to do is ask his beard for the secret formula.
Hopefully his beard will respond with a positive answer.
You're legendary ; )
What about the guys in ZZ Top!
Sounds good, I’m donating now.
We should viral this content...
Aubrey the real HERO!
Awesome guy. He's doing actually important work!
I want to make a difference as well. I want to help others and myself. I also study artificial intelligence now and want to switch to biology. Damn I feel the same as this man.
The only thing that doesnt age is dead things.
Starts w growing a legendary beard
I wish you the best !
@@et8736 Which is why the maintenance approach makes more sense than the prevention approach.
@@et8736 There are multiple species that show negligible senescence.
No more aging!
"Do not go gentle into that good night,
Old age should burn and rage at close of day;
Rage, rage against the dying of the light."
I want a "return to 25" pill.
You'll all see at 60....
@@DARisse-ji1yw 71 now...give anything to be 60 again...lol
@@bogee4u
Yup... tell the kids to enjoy youth while they have it... it goes quick !
@@bogee4u You will make it! Just maintain a healthy lifestyle, get the latest medicines, and one day, we will reach into the stars. You got this man
@@bogee4u buddy Research “nmn” is a pill you can take rn, it’s on amazon, do your research done I’m sure you’ll buy it
Truly awesome video!!
Great explanation of why aging research doesn't get enough funding: "we have chosen to give some of the aspects of aging disease-like names [e.g. cancer, atherosclerosis] and not other ones [e.g. sarcopenia, frailty]"
Hi! Thanks for creating videos that, in general and more specifically in this one, enriches life. I think it is a good idea if TEDxTalks adds english captions to the videos. That would let people add in a much more easily way subtitles in other languages which obviously will provide more views to the video. I offer myself to add spanish subtitles once the english captions are done and synced.
Pls for god sake fund people like him
That's really a great idea and something out of box. Thanks to TEDx.
Superb!! Thanks!!!
Please cure us from aging
Jesus came back to teach us immortality.
but honestly though, I'm a huge fan and I've been coming back here for years
such a wise, amazing man.
First we need to take care of the first problem of old age dying then we prevent aging and then were done this man is still with us today maybe he could give us the answer
Aging must be stopped...once and for all
Excellent! ZZTop is finally doing something about aging!
🤣🤣🤣
I think about this all the time!
Aubrey De Grey is clever thanks for upload :).
Excellent!
I admire his optimism!
Why hasn't this guy been on Sam Harris's podcast yet? Aubrey he's talked about having you on before, try and arrange it. You'd have a wonderful conversation and it would reach tonnes of ears!
I would love to watch an Aubrey de grey and David sinclair together in a conference!
Sinclair the sociopath. He stole NMN from our commons and put it into his personal ownership as his own personally owned research product, from which he hopes to rake in profits. My prediction is de grey by KO over Sinclair in the 2nd round
The world doesn't need ageing and death.
The world doesn't need overpopulation and food shortages
Have less children! Simple.
we can start by convincing the middle-easterners that. Their fertility rate is something ridiculous like 8.
We are far from overpopulation and mostly rich will be able to get this . People will still die because their beliefs they will help keep population down
well some of it does. But I agree...the longer we live the more we learn and the less likely we are doomed to repeat our mistakes as we do now...generation after generation.
I got the connotations and it inspired my innovative mind.
This is what I always wanted since I was in 2nd or 3rd grade. Yeah, people in my family tend to live into their 90s and I was only 7-8 at the time, but I knew that time would inevitably pass and I would be laying on my deathbed. So yeah give me a few centuries to live and hopefully the religious fanatics don't ban this stuff
} m
The nervous style of talking this guy has is both hilarious and contagious....anyway, thanx for the ideas and struggles to improve others lives...keep on till succeed!!!!
Gotta love trying to explain transhumanism and longevity science to your friends and getting laughed at and getting told it's "impossible" and "we'll all be dead before that happens" like really?
Gandalf De Grey. I have nothing but respect for this guy.
It's amazing that people don't understand what aging is, and even more so that solving aging is solving diseases. Aging is a T...n(sorry I'm keeping that one to myself) that we have to fight against(slow down) and also compensate against it's effects.
At 11:26 alternative
here is my simplified diagram | Antioxidents | - put into mouth |
you are totally true
Wooow... i am more interested on how we can finally win the fight on losing hair.... i am so jealous of his hair, i hope i have as much when i get to his age.
Heroic work! SENS.org/donate
I couldn't agree more. Heroic, saving future lives daily. You should definitely join the Healthspan Longevity Live Chat Discord Channel (discord.gg/ftSbffu), we are grouping up and spreading the word online. Aubrey shouldn't be alone, and we can shake the online communities and spread awareness.
If you want to live longer grow your own fruits and vegetables!
Donating to Aubrey is not going to help you when you are old.
Besides, Google will fund de Grey.
Buster Brown if Google were going to give to his foundation why haven't they done so?
what credentials does grey have? I see a lot of quacks on antiaging these days asking for donations
Johnny Lopez self taught biologist and ageing expert with formal phd training in computer science - watch some of the sens panel discussions or his debates - he knows his stuff!
Im gonna invent resurrection if immortality isnt invented within this guys lifetime. Imma save u gandalf
Toastie google "the common task". There is this Russian futurist who died over 100 years ago who proposed a radical idea to resurrect the dead using future science and technology. Over 100 billion people have died since the birth of mankind. Is it possible to resurrect the dead when all the brains information is destroyed? It seems like it's impossible but maybe some future humans will actually accomplish it who knows.
Resurrection is already a reality.
@@NehaQua1995 they can clone them
Check out cryonics/Alcor
Great vid
I made that same decision when I was about the same age only I’m about the same age is this guy and I’m still working on it but I have big plans
I actually sat in this ted talk and the only thing on my mind was "OMG! the comments that people are going to make once this hits UA-cam"
And you must be expecting a lot of replies to your comment ⊙﹏⊙
I mean why die, no one wants to die, so why do it, death cannot legally happen if you just say NO
Awesome info & really great to compare the biological concepts to the general maintenance we willingly provide to cars, etc...
It's also highly inaccurate, but at the same time I understand the utility of the metaphor; the most important thing that Aubrey De Grey has gotten across is that extending healthy human life, even for extremely long periods of time is not physically impossible, and should be conceptualized as being more akin to something like artificial general intelligence or fusion power-what one might argue are the "holy grails" of computer science and nuclear physics-that is to say something that is extremely difficult but possible and highly desirable, rather than something like perpetual motion or faster than light travel which are impossible to the best of our current knowledge.
@@dylanmah7791 well he's not even trying to "cure aging" just control the factors that cause it.
I have a question regarding this incredible issue, how much will the medications cost?
$60/month rn, Research “nmn”
I think we either need to end aging and age related diseases, or prove that our consciousness goes on after death. At least one of these two things.
And what makes you absolutely confident that our consciousness does continue after death? Please don't be because of religions..
@@Kurtis11266 He didn't say that he believed that.
I think it's unlikely that our consciousness lives on after death because simply put our brains create it some how and when the brain dies the entire thing deteriorates.
There is no real reason to assume that just because we don't understand consciousness yet that it doesn't die along with the rest.
Aubrey, I'm on board. Believe me, if I were any more on board I'd need to be hospitalized. I'm taking notes, reading, joining forums, and newsletters, and watching video after video trying to learn. But, you said over 10 years ago there'd be a 90% likelihood we'd solve it. There is little more a layperson like me can do than to learn about what you are doing and be an advocate. Still the deepest question I can so far think to ask is why aren't we there yet? What will be the "thing" that ends the questions you have so this can get implemented? Is there an answer to a question yet to be discovered that will be change things overnight? I don't want to take a wait and see approach to this! I'm 44, man... Will I be in the group that has the necessary escape velocity for significant life extension? Bottom line, what are your thoughts on a time frame now in 2017?
Michael Greve invested 10 million dollars in SENS because they're starting clinical trials for heart amyloid proteolytic antibodies next year. That heart amyloid is estimated to cause 50-90% of all deaths in centenarians. They're making amazing progress and we'll see it in less than a few years, because they're working in 7 directions at the same time.
I don't know if anyone reads these comments, but I have to say, after another week of researching this I have come to understand some of the challenges in getting this done. There really is a sea of information out there and this technology has many interrelated parts to it. I would love to have someone in the field provide their insight into the question though for confirmation and clarity. I'd like to also take the opportunity to mention, the population crisis argument is completely invalid. Please don't take this as an attack on your intellect. The population increase while a long term concern is not going to be a problem we can't deal with, and the knee jerk reaction though a natural one is quickly put to rest when one does the actual math. Not to mention the work being done on gene editing will be applied to agriculture as well vastly increasing production. These and other concerns are discussed thoroughly in Aubrey's and many others lectures and talks available to you at a click of the mouse. Secondly, you need to consider the positive consequences this technology will bring to humanity. It will be gradual, but we really are talking about what's called a post scarcity society. Examples include an end for the need of medicare. Health Care Act problems gone. Grandma won't be sick! Think big and have a little hope. This is coming. Let's just hope sooner than later. How can we say no to end end to things like chronic pain (first on my list), but more more importantly, malaria, cancer, heart disease, and blindness just to name a few.
I'm a final year student in biomedical sciences and a research assistant at a lab in Nevada. Aubrey's research looks great to me, check their publications page.
Hey Jonathan, good to hear you're on board! Come check out the healthspan & longevity discord live chat, should be easy to find via a quick google search. We've many motivated individuals like you who want to help get aging under medical control faster, anyone with a spare minute and access to a keyboard can help make an impact!!
I'm 22. What is your advice on doing. Funding or switch study to biology? I get excited reading your comment that I am not alone this curious.
I find it fascinating how some people are geniuses, because they tackle the right problems.
Then he certainly isn't a genius. And neither are you. Thanks for noticing.
Genetics just amaze me. It would be so cool to end disease and slow down progression of aging or "end aging" as he puts it.
11:13 the beard interfeard :)
Anyone with such a glorious face mane should be respected and listened to...same as mullets
....and Yosemite Sam!
What makes a big difference depends on who you are talking about.
For example, advances in prosthetic technology don't make much difference in your life unless yo happen to be an amputee. But as an amputee (since 1973) advances in prosthetic technology have made a huge difference in my life.
Only $40 million a year to advance this technology by 10 years?? Either this is a stretch or our society really can not allocate capital efficiently.
I support this wizard!!!
Watch that you don't turn into a toad ... surely nobody will kiss you ...
Hahaha we graduated from Hogwarts
once you guys solve it, you gonna sell it?
It’s buyable right now, research nmn it’s sold on amazon
I was thinking when this guy making a stir fry food, on one of those fiery explosions hahaha
Aim was perfect.
With a beard that epic, you can do anything. This mans ideas are inspirational, what an intellect.
Rasputin talking about longevity, now this seems fit.
Inspiring
How about damage prevention.... i.e better diet, etc?
Why are rich people - who "have it all" but are otherwise just like the rest of us when it comes about aging - not onboard on this en mass? Where is Bill Gates and the other 1% ???
Too busy profiting on the systems of people dying and drugs being sold to treat sick people sadly.
Juls CestMoi start writing them e-mails with links to such research I'm not joking
@@AG-qo5vt Yes because they really want to help us and they have our best interests at heart 😂😂
+paul w Yeah sure but when you got tech involved you can eliminate it completely.
+Edvin1011 That's not true for all people, and I would wager it's most definitely not true for most billionaires.
amazing how low the view count is.
Yea right. You just don't understand his thinking
3:44: "EVERYBODY WANTS TO BE HEALTHY. Being sick is seriously not fun. Who wants to be sick tomorrow?". That's totally the whole point.
What a guy! What an idea!
The same rhetoric, but slightly improved. So that's good... but it's quite sad that he has to do the advocacy himself. He should have all the resources available, just being able to execute the scientific process at maximum efficiency. Theory after theory, paper after paper, with the support of the global scientific community.
But I think his old job (AI research), and some kind of web of scientific inquiry is required to get something like this to take off.
Maybe AI are the solution to the complexity to the human body; a more advanced mind capable of solving the problems that a lesser human mind couldn't.
The thing is that governments and elites don't see civilian death to be problematic or even a priority. if anything living longer creates a bigger problem and that is overpopulation. We are already overpopulated today to now bring in the technology that will enable us to live longer will be catostrophic. If this technology exists today it would funded by the elites for private use only and not for the world to have access too. in my opinion only the wealthy will have access to this.
@@SinerAthin Then you would definitely need it since you have a big problem thinking for yourself.
The only requirement to get something like this to take off is a degenerated clown like Grey ...
@@mujotomi ?
content at 14:51
amazing
BASED Aubrey!
I am looking lot of anti ageing immortality videos... looking forward to be young
The holy grail has been found and it shall be given only to those who have overcome.
Vishvesh Tadsare yes I had the vision of the philosophers stone it’s beautiful to receive this gift
This doctor is has made a paradigm shift to view ageing.
ageing - the ratio of degeneration of our cells exceeds over and above our regeneration of cells
WE made no progress in fighting against aging... but THEY did!
I didn't know ZZ Top became a biologist.
powerfull
What is the role of diets in slowing the aging process?
Everything. Start by googling Dr Nun Amen Ra. He gives good information on this.
What he was saying was important unfortunately the message was lost in the beard.
He drinks a lot of craft beer... saw a doc where he's drinking at 10... lol.
What can we do now? Intermintent fasting & low carb diet, NAD+, Cycloastragenol (telomerase activator), TRT, hgh....
No, you just have to get a proper job, you lazy bum.
Nice!
Damage repair seems possibly useful but insufficient to solve aging. The problem isn't just that damage accumulates - it accumulates faster and faster as you age. So you do eventually need to find a way to slow that down.
A wise comment. Another approach is represented by scientist like David Sinclair, those dealing with epigenetics.
Good point but I believe the earlier you start anti-aging measures the slower it'll accumulate.
you don't understand yet