► 💊Antibiotics Lectures: www.medicosisperfectionalis.com/products/courses/antibiotics/ 💉 📜 My Notes, cases and courses www.patreon.com/medicosis/ 😅 If you like mnemonics, try Picmonic: www.picmonic.com/referrals/JK55NQXQQB9JLC119 📕📗 Books that I recommend, www.amazon.com/shop/medicosisperfectionalis
Hello sir i want to know something sir i am herion addict and my vitamin b12 is very low can i use vitamin b12 injections in addiction of herion please help me sir tell me i am a addict by mistake and from india my english is not good but i try you understand my problem and help me sir please reply
Appreciate video content! Sorry for chiming in, I would appreciate your thoughts. Have you heard the talk about - Taparton Sturdy Nerves Takeover (should be on google have a look)? It is a good one off product for Getting rid of Neuropathy minus the headache. Ive heard some incredible things about it and my cooworker finally got excellent results with it.
So i've watched 26 videos of this playlist within 3 or 4 days, and i'm speechless!!! I really like how your videos are not that long and by the same time are full or usefull information, plus the way you explain is so clear and you even make me laugh at some words of yours which is quite interesting and positive! I really ENJOY watching your videos. Thanks again and wish you all the best in your life!.
Most informative so thank you for taking the time of explaining this in great detail. My Hematologist has written a report to my doctor noting that I have developed mild Pancytopenia and have already started on B12 injections last month. My B12 is within normal range however the HoloTC (Holotranscobalamin)level was abnormal so is still being looked into as to why. I have been having severe Hemiplegic Migraine with other Neurological conditions over the past 3 years.
Just saying, I am a committed vegan and obtain B12 from cereals. Keeping well after circa 10 years. Animal products also have their drawbacks, especially red, processed meats and dairy, best avoided. Good video, thanks and best wishes. 🕊️🧡✨
I came to this video in the hopes that it would help me understand my B12 deficiency after seeing a neurologist for my symptoms. It was very helpful in understanding the processes; however, I just wish the doctors could tell me the REASON for my deficiency. I’ve been receiving injections but I’d still like to know why.
Sometimes, it’s difficult to identify the cause. If your symptoms are getting better with the treatment plan, then you’re on the right track. If not, see another doctor. I wish you the best!
Do you have stomach or digestion issues? Mine is from celiac disease which ruined my stomach lining so I couldn’t take in vitamins and got really malnourished
@@oxyroid I do have GI issues. I go to the bathroom numerous times a day. I normally can’t plan long outings from home because I’m afraid I’ll need to use the bathroom. It’s pretty terrible. I’ve mentioned this to my doctor many times but she has not had an interest in testing me for anything.
2 years ago i used metformin for weight loss, i lose wieght but got ice pick headach which i never experienced in the past, after that i got grey hair in th area of ice pick headache. Than i stop using metformin and from past 1 and half years im using vitamin B12 sublingual, Now i get less pain and some of grey hair turn blach. But now due to my stress and depression nothing works, my hair turns grey faster. Im 32. Now what can i do. Also premature grey hair is not in my family genetics .
Try to take B12 injections. Very big difference. Your r protein could be not created by body and b12 not absorbed. Move to another city out of depressive environment.
American Academy of Neurology: People with inflammatory bowel disease may also be at risk for developing nerve damage and other neurological problems, according to research that will be presented at the American Academy of Neurology’s 59th Annual Meeting in Boston, April 28 - May 5, 2007. Inflammatory bowel disease includes digestive disorders such as ulcerative colitis and Crohn’s disease that cause swelling and/or bleeding in the intestines. For the study, researchers compared 103 people with Crohn’s disease and ulcerative colitis to 51 people with other digestive disorders, such as irritable bowel syndrome, gastritis and chronic heartburn. The researchers found that those with inflammatory bowel disease were about four times more likely to develop neuromuscular conditions, including carpal tunnel syndrome and small fiber neuropathy, which causes pain and lack of feeling in the feet. Those with bowel disease were also more than six times more likely to also have a disorder called sensorimotor polyneuropathy, a nerve disease that can cause weakness, pain, and numbness. These diseases were more common in women with bowel disease than men. “Inflammatory bowel disease patients commonly suffer from several other medical conditions, like B12 deficiency and glucose intolerance. These nerve conditions we have reported are often not diagnosed by their primary care physicians,” said lead study author Francisco De Assis Gondim, MD, MSc, PhD, Professor of the Federal University of Ceará in Ceará, Brazil, and a member of the American Academy of Neurology. “People with inflammatory bowel disease who develop new symptoms, such as pain or numbness in the feet, should see a doctor.”
I think I am getting addicted to your videos 🤣🤣 I really hope I can get into medical school and be a good doctor I feel I understand almost all the concepts you discuss. Probably the challenging part is to memorise it. I hope I eventually get there.
By the time you will read all this in medschool, you will memorise it and better than your classmates because you will be studying it for the second time again!
@@starrysky1588 I really hope so. But the problem is that I cannot study medicine in my country as they mainly offer it for Highschool graduates. I got admitted in NewZealand as an international student but I don’t have money to study. My university will start in three months and I don’t know how to pay my fees yet lol 😂 If no miracles happen, I may kiss my offer goodbye 🙈
@@ahmadaljazeeri9287 Oh I see! Don't worry God will create some solution for you. Why don't you try in a more affordable country like Pakistan? We have a lot of international students here. And don't worry people in countries like new Zealand or Australia work part time and can pay their fee. Looking at your passion, I wish so much that you become a doctor someday!
Greetings of the day Sir, you are doing a great job. Your lectures are very impressive, precise, understandable & providing great concepts. Sir I want to ask you does Gastric sleeve surgery can cause Vitamin B12 deficiency. Thanks
Yes, it can, but to a lesser degree than Roux-en-Y gastric bypass. Here is a link to an abstract of a systematic review on the subject. pubmed.ncbi.nlm.nih.gov/24091055/
Thank you! SO complex. PS: some chronic parasitic infections eat our RBCs and B-12. Over several years time they cause Malabsorption, chronic fatigue, B-12 anemia. Hookworm, Babesia, and Fish Tapeworm. Case numbers exploding. Doctors do not know about this!!! And the lab tests for them are often false-negative. 😖🤬 Thanks for helping us.
Exactly, to bad they don’t test here in the states until they’ve caused lots of damage and making tons of $ off of people and insurances. It’s a cheap test and cheap treatment. Unfortunately they recommend we treat our animals for them at least twice a year but not humans even when we are around them on a daily basis. Not including all the other places we can be exposed to them such as restaurants, unwashed fruit ect.. it just doesn’t make sense to me. Thankful we are able to get the treatment for them from a local place that was willing to get us some. One time treatment. One pill then one more 6 weeks later to treat eggs that may have not been rid of. They recommend doing this at least two times a year to be safe.
@@MariaReyes-jp4lb my sister is dying because she can no longer absorb B12. Do you know if it's possible for her to buy these pills before it's too late? Thank you.
@@PeacefulPatriotforJesus many people have even taken the animal parasite med as it has the same exact ingredients and tested to be safe. She should detox once done with the treatment. Simple.
@@PeacefulPatriotforJesus I am so sorry i just now saw your question. I hope she healed and still alive and better. I’d try anything. Take ivermectin or fenbendazol (not sure of the spelling but they are anti parasitical and also detoxes heavy metals ect,) hugs ♥️🙏.
If alcohol prevents folate absorption and folate deficiency is a cause of macrocytic anemia then alcoholism can cause both megaloblastic (folate def) and non-megaloblastic (chronic alcoholism)?
God bless you soo much,I appreciate all your videos and efforts,you're so brilliant and innovative in educating us....I love you. thank you.. I appreciate you ♥️♥️♥️♥️keep up the good work
how about other b vitamin (B1,B6,B9,B5) gets absorbed in body similar to B12 ? If someone has B12 deficiency will there be problems with other B vitamins as well ?
Great question! Yes. I have been recently injecting methycobalamin and feel so much better. My GP kept saying that my b12 levels were too high in my blood work and to stop taking it but I was barely taking any supplemental form at all so it clearly didn’t make any sense. Then I learned that high b12 levels in the blood can actually indicate a deficiency. I was having severe heart palpitations and horrific anxiety amongst other odd symptoms. I am homozygous for two MTHFR mutations and decided to do my own research. Since doing my intramuscular injections I feel like a different person so it’s clear that I was in fact deficient and my GP was very wrong. Also Viatmin K2 and a very low dose of Lithium Orotate will help the absorption of B12 a lot. Hope this helps a little 😊
Peaka01 Absolutely correct! Methylfolate is the correct form for us mutants 😉 It can cause anxiety however.. so in my experience it is best to start very slowly and work up to a comfortable level. 😊
Panda1122 A I've read several medical journals regarding high b12 levels and the conclusion was that it was not getting metabolized due to the mutation.
I have some questions - To which protein is cobalamin bound in the liver? Is it still transcobalamin? Is it correct that amylase cleaves cobalamin and „animal protein“ as it actually serves as an enyzme for carbonhydrate metabolism? Thanks a lot!
Fun fact: it's actually quite rare for a vegan to be B12 deficient these days. Plant-based milks and vegan products are now fortified with both B12 and folate
@@MedicosisPerfectionalis You are incorrect. The best source is not from animal products. b12 is made from bacteria....however the world is more sterile now. We used to get our b12 from pond water (water is now treated) and we triple wash our produce (soil )...so it's affect the general population (meat eaters and vegans). Animals are supplemented with b12 so why not get it directly and cut the middleman? go plant based
Does taking cobalamin under the tongue by pass the whole process with intrinsic factor? Can it be absorbed by those who have trouble absorbing due to their intrinsic factor?
I am a vegan who is making sure I get enough B12; but my meat-eating grandfather supposedly died of pernicious anemia. Is it possible to die *from* pernicious anemia? Or is it really death from *complications* of pernicious anemia?
I have kidney disease 3 stage but the doctor telling me I can’t eat things that have potassium I been eat spinach because I heard is good for the iron but not for my kidneys check that out now I feel weak I had to go to a health store and bring up the iron so tell me what is good that I can eat that won’t affect my kidneys 😩
Fish tape worm!!!!! Yikes, and I love sushi. However, I'm still having a blast learning stuff I may never need to know. I try not to mention any of this in social settings as it tends to annoy some people. And I don't as a rule mention parasites.
Just found your video, great! 3 years ago I had bleeding due to ulcers, due to H pylori, from there they told me I had pernicious anemia, I suppose to get B12 shots every month for life, however my anemia improved, the Dr. said I don’t need shots, now my B12 is borderline and I do not have anemia, why does this happen?
this only discusses very drastic symptoms. what about subtle symptoms like high triglycerides, higher homocysteine and slow memory loss, in cases where b12 remains low in spite of oral supplements.....
Hello 👋 thank you very very much for your efforts 🌷🌷 But i have two questions one is amylase for carbs digestion ? But u said it help to dissociate B12 from protein ? Is this mean amylase has two functions ??? The other question is normal flora in our intestine also synthesized B12 true ! ? If the person is strict vegan B12 not become zero ?? And don’t reach to severe state ?? Can you clarify this to me ?? And again thank you 😊
Answer to: Q1: yes, amylase has more than one function. Q2: just because it’s in your gut, doesn’t necessarily mean that you will absorb it in sufficient amounts (i.e. the concept of bioavailability). Instead of looking into theories, look into the statistical scientific studies of patients with B12 deficiency, a huge percentage of them are strict vegans. Hope it helps! Good luck!
Medicosis Perfectionalis Ooh thank you I understand now I’m not vegan but i know that intestinal flora made it so i think 🤔 the body can get B12 from it
Hi thank you for this video. I am not in the medical profession and I am getting in touch because I keep getting elevated vitamin b in my blood results even when I am not taking vitamin tablets. It keeps coming up as abnormal on my blood test results but my healthcare professional does not explain why. I heard you can still have a vitamin b definitely with elevated vit b in blood. Could you help at all? Could the elevated vitamin b in blood mean I am not processing it correctly? Thank you so much.
Bcoz it interferes with neurological symptoms improvement, which is due to b12 deficiency. After loading doses of b12, then folic acid should be given, meaning first b12 levels should be raised . After loading we have to take folate as well, because both work together to make red blood cells along with iron. Also folate helps in processing b12.
I have discussed most of these causes in other videos in my “hematology” playlist. These include: - iron deficiency anemia. - anemia of chronic disease. - sideroblastic anemia. - Thalassemia. Each one of these is a video (or more) that I already did.
I got some lad work it’s showing my b12 is 377 and in the ranges says ppl with 400 less experienced symptoms. I been loosing hair my hand and feet get numb and cold , I have Poor circulation what should I do
You should start supplementing according to your symptoms. If you are vegan, then you have to either change diet or take supplement, if you are taking non veg frequently, still symptoms, then you have difficulties in absorbing b12 from food , in that case you need injections. Serum b12 tests are not reliable. We should always look for symptoms and try to treat them. It's true some people feel symptoms even in 400 level and some don't even in 200 range. The only way is supplementing and seeing whether you feel better, this is what I did. I am on b12 injections. Along with this you also need to take folate in order to process b12, they both work together.
Sometimes when I eat meat it feels like I am not digesting it properly. I am suffering slot from either B12 or B6. I feeling very bad. Tired, bloated, dry skin, esp scalp, esp. I feel like there is something above my navel. I feel thirsty, I lost glow on my face and much more..
Hi, would you help me clarify if this anemia is or not hyperchromatic? In italian wikipedia page it says: "it used to be called hyperchromatic anemia" and one of my professors wants to hear "hyperchromatic" during the exam but i'm not sure :/
Why would it be self-contradictory? You could have less RBCs (anemia) but the ones present could be very pigmented (I don't know any condition but logically it's possible).
Check Harrison’s internal Medicine...It states that clearly; when RBCs acquire more hemoglobin, they become larger, not darker! I am also aware that Robbin’s pathology still uses the term hyperchromic!
what is this lemon yellow skin? Is it jaundice. Both folic deficiency and B12 deficiency lead to big blood cells, which will be break down by the macrophage. Does this leads to jaundice?
never mind. I believe lemon skin is caused by decreased Hgb and jaundice. pallor+jaundice probably will be yellow. Don't know what skin color change will happen in Asian people. We are born yellow.
![B12 Deficiency and Neurological Disease [Explained by Neurologist]](http://i.ytimg.com/vi/OPHWGDIGDLw/mqdefault.jpg)
► 💊Antibiotics Lectures: www.medicosisperfectionalis.com/products/courses/antibiotics/
💉 📜 My Notes, cases and courses www.patreon.com/medicosis/
😅 If you like mnemonics, try Picmonic: www.picmonic.com/referrals/JK55NQXQQB9JLC119
📕📗 Books that I recommend, www.amazon.com/shop/medicosisperfectionalis
Hello sir i want to know something sir i am herion addict and my vitamin b12 is very low can i use vitamin b12 injections in addiction of herion please help me sir tell me i am a addict by mistake and from india my english is not good but i try you understand my problem and help me sir please reply
Hi dear,
How are you?
I strongly recommend that you talk to your doctor!
@@MedicosisPerfectionalis hello sir i am fine and now in recovery and using cyanocobalamin for increase vitamin b12
Stay safe
Appreciate video content! Sorry for chiming in, I would appreciate your thoughts. Have you heard the talk about - Taparton Sturdy Nerves Takeover (should be on google have a look)? It is a good one off product for Getting rid of Neuropathy minus the headache. Ive heard some incredible things about it and my cooworker finally got excellent results with it.
Your channel is a million times more informative than my lectures, thank you so much for everything!
My pleasure 😇
This is much more helpful than a whole lecture at college. Thanks a lot!
Thank you so much 😊
So i've watched 26 videos of this playlist within 3 or 4 days, and i'm speechless!!! I really like how your videos are not that long and by the same time are full or usefull information, plus the way you explain is so clear and you even make me laugh at some words of yours which is quite interesting and positive! I really ENJOY watching your videos. Thanks again and wish you all the best in your life!.
Thank you so much! I appreciate you!
📝 Download my handwritten notes: www.medicosisperfectionalis.com/
🩸 Hematology Playlist: ua-cam.com/play/PLYcLrRDaR8_eoNz6dxXolh1XMEietcniU.html&si=tomFsUjAgOKhOJVq
I firstly appreciate you for your time and explanation, but you need to expand your explanation time than this.
I cant belive that you´ve just made a reference to Oasis, this channel is incredible! Thanks for your videos and effort, cheers from Argentina.
Thank you so much!
I appreciate you!
Would you please help me by sharing?
Your voice in my head...What a amazing teaching skills ...You are the great....
that was great! waaaay more than I anticipated from UA-cam but I learned a lot. thank you.
My pleasure 😇
I watch all ad on your vedio,,
i didn't watch it because I am busy but feel that content is perfect,,
Thank you so much 😊
08:17 I sense an Oasis fan... geez Dr Medicosis Perfictionalist is just Perfection!!
Who's "Oasis"?
No man, we can't thank you enough !
This touches my heart! Thanks for your encouragement!
Excellent explanation of pathogenesis and diagnosis of Vitamin B12
Thank you 🙏
thank you for the explanation. you forgot to add tests for pernicious anemia including anti-intrinsic factor Ab and anti-parietal cells Ab.
You're right.
Most informative so thank you for taking the time of explaining this in great detail. My Hematologist has written a report to my doctor noting that I have developed mild Pancytopenia and have already started on B12 injections last month. My B12 is within normal range however the HoloTC (Holotranscobalamin)level was abnormal so is still being looked into as to why. I have been having severe Hemiplegic Migraine with other Neurological conditions over the past 3 years.
Best of luck to you!
Just saying, I am a committed vegan and obtain B12 from cereals. Keeping well after circa 10 years. Animal products also have their drawbacks, especially red, processed meats and dairy, best avoided. Good video, thanks and best wishes. 🕊️🧡✨
Yayyy our genius has a video about my presentation title 💃
Thank you 🙏
Thank you! these videos are great. very easy to understand. keep them coming please.
Sure!
Thank you so much for watching!
Thank you I can’t thank you enough !!!!❤❤❤ third block ,10:45am ,second week
I came to this video in the hopes that it would help me understand my B12 deficiency after seeing a neurologist for my symptoms. It was very helpful in understanding the processes; however, I just wish the doctors could tell me the REASON for my deficiency. I’ve been receiving injections but I’d still like to know why.
Sometimes, it’s difficult to identify the cause.
If your symptoms are getting better with the treatment plan, then you’re on the right track. If not, see another doctor.
I wish you the best!
Do you have stomach or digestion issues? Mine is from celiac disease which ruined my stomach lining so I couldn’t take in vitamins and got really malnourished
@@oxyroid I do have GI issues. I go to the bathroom numerous times a day. I normally can’t plan long outings from home because I’m afraid I’ll need to use the bathroom. It’s pretty terrible. I’ve mentioned this to my doctor many times but she has not had an interest in testing me for anything.
@@meggbaker9380 look into SIBO if you haven't already.
2 years ago i used metformin for weight loss, i lose wieght but got ice pick headach which i never experienced in the past, after that i got grey hair in th area of ice pick headache. Than i stop using metformin and from past 1 and half years im using vitamin B12 sublingual, Now i get less pain and some of grey hair turn blach. But now due to my stress and depression nothing works, my hair turns grey faster. Im 32. Now what can i do. Also premature grey hair is not in my family genetics .
Try to take B12 injections. Very big difference. Your r protein could be not created by body and b12 not absorbed. Move to another city out of depressive environment.
American Academy of Neurology:
People with inflammatory bowel disease may also be at risk for
developing nerve damage and other neurological problems, according to
research that will be presented at the American Academy of Neurology’s
59th Annual Meeting in Boston, April 28 - May 5, 2007.
Inflammatory bowel disease includes digestive disorders such as
ulcerative colitis and Crohn’s disease that cause swelling and/or
bleeding in the intestines. For the study, researchers compared 103
people with Crohn’s disease and ulcerative colitis to 51 people with
other digestive disorders, such as irritable bowel syndrome, gastritis
and chronic heartburn.
The researchers found that those with inflammatory bowel disease were
about four times more likely to develop neuromuscular conditions,
including carpal tunnel syndrome and small fiber neuropathy, which
causes pain and lack of feeling in the feet. Those with bowel disease
were also more than six times more likely to also have a disorder called
sensorimotor polyneuropathy, a nerve disease that can cause weakness,
pain, and numbness. These diseases were more common in women with bowel
disease than men.
“Inflammatory bowel disease patients commonly suffer from several other
medical conditions, like B12 deficiency and glucose intolerance. These
nerve conditions we have reported are often not diagnosed by their
primary care physicians,” said lead study author Francisco De Assis
Gondim, MD, MSc, PhD, Professor of the Federal University of Ceará in
Ceará, Brazil, and a member of the American Academy of Neurology.
“People with inflammatory bowel disease who develop new symptoms, such
as pain or numbness in the feet, should see a doctor.”
You’re so cool 👏🫶🏻 thanks for doing these videos. You are very good at explaining and it’s fantastic what I’m learning from your channel ❤
Thank you so much!
I think I am getting addicted to your videos 🤣🤣
I really hope I can get into medical school and be a good doctor
I feel I understand almost all the concepts you discuss.
Probably the challenging part is to memorise it. I hope I eventually get there.
Wow so you are watching these videos even though you are not a medical student?? Then there is so much hope you will become a doctor...an amazing one!
By the time you will read all this in medschool, you will memorise it and better than your classmates because you will be studying it for the second time again!
@@starrysky1588 I really hope so. But the problem is that I cannot study medicine in my country as they mainly offer it for Highschool graduates. I got admitted in NewZealand as an international student but I don’t have money to study. My university will start in three months and I don’t know how to pay my fees yet lol 😂
If no miracles happen, I may kiss my offer goodbye 🙈
@@ahmadaljazeeri9287 Oh I see! Don't worry God will create some solution for you. Why don't you try in a more affordable country like Pakistan? We have a lot of international students here. And don't worry people in countries like new Zealand or Australia work part time and can pay their fee. Looking at your passion, I wish so much that you become a doctor someday!
@@starrysky1588 thank you Zahra sister :) I will do my best and try hard to one day become a doctor. I appreciate your encouragement so much!
Okayyy. this is myy fvrt youtube channel
Thank you 😊
Greetings of the day Sir, you are doing a great job. Your lectures are very impressive, precise, understandable & providing great concepts. Sir I want to ask you does Gastric sleeve surgery can cause Vitamin B12 deficiency. Thanks
Yes, it can, but to a lesser degree than Roux-en-Y gastric bypass. Here is a link to an abstract of a systematic review on the subject. pubmed.ncbi.nlm.nih.gov/24091055/
This B12 is a promiscuous vitamin. First it binds to R protein, then to intrisic factor and in the end to the transcobalamin
Thank you for all the videos. They're extremely helpful.
You’re very welcome 😊
@@MedicosisPerfectionalis does this causes sevier back pain in waist
I m new at your channel it's wonderful thanks for sharing your precious knowledge with us..
May Allah bless uh ❤️❤️❤️
Thank you 🙏
You too!
Thank you! SO complex. PS: some chronic parasitic infections eat our RBCs and B-12. Over several years time they cause Malabsorption, chronic fatigue, B-12 anemia. Hookworm, Babesia, and Fish Tapeworm. Case numbers exploding. Doctors do not know about this!!! And the lab tests for them are often false-negative. 😖🤬 Thanks for helping us.
Good to know. Indeed
Exactly, to bad they don’t test here in the states until they’ve caused lots of damage and making tons of $ off of people and insurances. It’s a cheap test and cheap treatment. Unfortunately they recommend we treat our animals for them at least twice a year but not humans even when we are around them on a daily basis. Not including all the other places we can be exposed to them such as restaurants, unwashed fruit ect.. it just doesn’t make sense to me. Thankful we are able to get the treatment for them from a local place that was willing to get us some. One time treatment. One pill then one more 6 weeks later to treat eggs that may have not been rid of. They recommend doing this at least two times a year to be safe.
@@MariaReyes-jp4lb my sister is dying because she can no longer absorb B12. Do you know if it's possible for her to buy these pills before it's too late? Thank you.
@@PeacefulPatriotforJesus many people have even taken the animal parasite med as it has the same exact ingredients and tested to be safe. She should detox once done with the treatment. Simple.
@@PeacefulPatriotforJesus I am so sorry i just now saw your question. I hope she healed and still alive and better. I’d try anything. Take ivermectin or fenbendazol (not sure of the spelling but they are anti parasitical and also detoxes heavy metals ect,) hugs ♥️🙏.
If alcohol prevents folate absorption and folate deficiency is a cause of macrocytic anemia then alcoholism can cause both megaloblastic (folate def) and non-megaloblastic (chronic alcoholism)?
God bless you soo much,I appreciate all your videos and efforts,you're so brilliant and innovative in educating us....I love you. thank you.. I appreciate you ♥️♥️♥️♥️keep up the good work
Thank you so much 😊
how about other b vitamin (B1,B6,B9,B5) gets absorbed in body similar to B12 ? If someone has B12 deficiency will there be problems with other B vitamins as well ?
All the b vitamins work together, if you are b12 deficient then you need to take a b complex too.
So b12 deficiency produce iron defiency too?
No they are unrelated but may occur simultaneously.
What if someone has a MTHFR mutation and can't utilize the standard form of B12? Is it true that only methyl b12 is effective?
It’s my understanding that people with the MTHFR mutation shouldn’t take folic acid supplements
Great question! Yes. I have been recently injecting methycobalamin and feel so much better. My GP kept saying that my b12 levels were too high in my blood work and to stop taking it but I was barely taking any supplemental form at all so it clearly didn’t make any sense. Then I learned that high b12 levels in the blood can actually indicate a deficiency. I was having severe heart palpitations and horrific anxiety amongst other odd symptoms. I am homozygous for two MTHFR mutations and decided to do my own research. Since doing my intramuscular injections I feel like a different person so it’s clear that I was in fact deficient and my GP was very wrong. Also Viatmin K2 and a very low dose of Lithium Orotate will help the absorption of B12 a lot. Hope this helps a little 😊
Peaka01 Absolutely correct! Methylfolate is the correct form for us mutants 😉
It can cause anxiety however.. so in my experience it is best to start very slowly and work up to a comfortable level. 😊
Panda1122 A I've read several medical journals regarding high b12 levels and the conclusion was that it was not getting metabolized due to the mutation.
Aimee Murphy Thanks Aimee. Yes exactly. It’s scary that so many Drs are still unaware of this. Thanks 😊
We know ,what lovely doctor...
We want u to do CVS videos...what do u think
Will do all topics one day...That’s my dream!
I have some questions - To which protein is cobalamin bound in the liver? Is it still transcobalamin? Is it correct that amylase cleaves cobalamin and „animal protein“ as it actually serves as an enyzme for carbonhydrate metabolism? Thanks a lot!
Desastroes Desolat specify😂🤦♂️you keep on contradicting yourself instead of asking a question
Thanks so much for this incredible explanation with drawings! I really enjoyed it.
My pleasure...Welcome to the channel :)
Medicosis when is the best time to take B12 and can it be taken with B1 and B6 and Magnesium together?
Multivitamin tablets can contain all three...So, no problem.
"That's the story Morning Glory! "
😂😂
Allways You are the best. 💖💖💖💖💖💖💖💖💖💖💖💖💖💖💖 thank You very much for this great thing.. go a head🌹🌹
Thank you 🙏
Fun fact: it's actually quite rare for a vegan to be B12 deficient these days. Plant-based milks and vegan products are now fortified with both B12 and folate
But worldwide, that's a small percentage.
@@MedicosisPerfectionalis You are incorrect. The best source is not from animal products. b12 is made from bacteria....however the world is more sterile now. We used to get our b12 from pond water (water is now treated) and we triple wash our produce (soil )...so it's affect the general population (meat eaters and vegans). Animals are supplemented with b12 so why not get it directly and cut the middleman? go plant based
Do you have evidence that B12 deficiency didn’t exist before we sterilized the water?
D Ou is never heard that one😂 sounds made up
MedicalS
Synthetic supplements😷👎
You can work on a course to teach Professors how to really teach , Thank you Million times.
I appreciate you!
I enjoyed this I have a B12 deficiency, ..will check out the , macrocytic
I wish you the best of luck
Help me to get rid of neurological problem and eye blurness if yours is fixed ?
I surely can't Thank you enough...
Don’t mention it! Thanks for your comment!
@@MedicosisPerfectionalis I have got University exams in two weeks. With your Help and GODs Grace ill surely pass my exams.. 😊
I certainly hope so...Best of luck to you! Keep in touch!
chat.whatsapp.com/FVtPrBmTgTF9KhmnwXa3fF join this for b12 deficiency
Does taking cobalamin under the tongue by pass the whole process with intrinsic factor? Can it be absorbed by those who have trouble absorbing due to their intrinsic factor?
Yes because it is being absorbed directly into the blood stream which bypasses your stomach
What is the cause of low transcobalin? How would you treat this?
Great work sir🙌 thank you so much :)
Most welcome 😊
I am a vegan who is making sure I get enough B12; but my meat-eating grandfather supposedly died of pernicious anemia. Is it possible to die *from* pernicious anemia? Or is it really death from *complications* of pernicious anemia?
meat contains heme iron which is bad..
Pernicious anaemia itself means that a person can't absorb b12 from food and supplement, they survive only on b12 injections.
You are doing such a great job. Your videos made it so easy for me to understand everything. Thankyou :)
Awesome 👏
Please share!
Liked and previously Subscribed.
Thank you 😊
you are the best!!
Thank you so much 😊
The thanks is for you 😍
You’re very welcome 😊
Thanks for your brief videos. What is the solution. Please I need reply if uiu have time or is it in your previous video.
Solution of what?
I mean food or medicine for this vitamin in your body thanks.
thanks alot doctor you always make it clear👏✌👌
You’re always welcome...Thanks for taking time to leave this nice comment!
So, if I am hearing you correctly; basically, I can be a vegan for eight years at a time followed by a meat fueled cheat year?
Also, Love your videos!
No , me can’t thank you enough ❤❤
What b12 dose do you recomend for maintnece as a vegan?injectable..
Regards
I have kidney disease 3 stage but the doctor telling me I can’t eat things that have potassium I been eat spinach because I heard is good for the iron but not for my kidneys check that out now I feel weak I had to go to a health store and bring up the iron so tell me what is good that I can eat that won’t affect my kidneys 😩
brilliant as usual
Thanks 🙏
Fish tape worm!!!!! Yikes, and I love sushi. However, I'm still having a blast learning stuff I may never need to know. I try not to mention any of this in social settings as it tends to annoy some people. And I don't as a rule mention parasites.
You’re right.
Any cure for pernicious anemia?
Just found your video, great! 3 years ago I had bleeding due to ulcers, due to H pylori, from there they told me I had pernicious anemia, I suppose to get B12 shots every month for life, however my anemia improved, the Dr. said I don’t need shots, now my B12 is borderline and I do not have anemia, why does this happen?
Some people can not digest b12 from our foods.
Pleas biochemestry lecturs like the hematology lecturs that is very helpful thhanks budy
Sure! Stay tuned!
can explain why fetal neural tube defect occur in vitamin b12 deficiency?
this only discusses very drastic symptoms. what about subtle symptoms like high triglycerides, higher homocysteine and slow memory loss, in cases where b12 remains low in spite of oral supplements.....
Nice explanation ,Thanks
My pleasure 😇
Thank you sir
I am facing very related symptoms of vitamin b12 deficiency. I am purely vegan even no eggs. How to overcome deficiency in that case?
I’m no doctor, but I did watch the video. It seems you have to eat animals and eggs
Sir I m getting ur all points i wants to remember these all like a story in mind but I don't know how to make it possible
Hello 👋 thank you very very much for your efforts 🌷🌷
But i have two questions one is amylase for carbs digestion ? But u said it help to dissociate B12 from protein ? Is this mean amylase has two functions ???
The other question is normal flora in our intestine also synthesized B12 true ! ? If the person is strict vegan B12 not become zero ?? And don’t reach to severe state ??
Can you clarify this to me ??
And again thank you 😊
Answer to:
Q1: yes, amylase has more than one function.
Q2: just because it’s in your gut, doesn’t necessarily mean that you will absorb it in sufficient amounts (i.e. the concept of bioavailability).
Instead of looking into theories, look into the statistical scientific studies of patients with B12 deficiency, a huge percentage of them are strict vegans.
Hope it helps!
Good luck!
Medicosis Perfectionalis
Ooh thank you I understand now
I’m not vegan but i know that intestinal flora made it so i think 🤔 the body can get B12 from it
Hi thank you for this video. I am not in the medical profession and I am getting in touch because I keep getting elevated vitamin b in my blood results even when I am not taking vitamin tablets. It keeps coming up as abnormal on my blood test results but my healthcare professional does not explain why. I heard you can still have a vitamin b definitely with elevated vit b in blood. Could you help at all? Could the elevated vitamin b in blood mean I am not processing it correctly? Thank you so much.
Your the best thanks alot ...just one point in 8:26 its methionine synthase not homocystin
You’re absolutely correct...It’s called methionine synthase or homocysteine methyl transferase.
Which writer book of medicine do you prefer for making the video's?
Harrison’s, Davidson’s, Goldman-Cecil and Goljan.
Thank you
Why folate should not be given in b12 defciency kindly explain
Bcoz it interferes with neurological symptoms improvement, which is due to b12 deficiency. After loading doses of b12, then folic acid should be given, meaning first b12 levels should be raised . After loading we have to take folate as well, because both work together to make red blood cells along with iron. Also folate helps in processing b12.
"Thats the end of the story... morning glory" wtf dude 😂😂
Savage mode
Very Interesting, thank you,
My pleasure 😇
I love your videos! Just too funny! :)
Thanks a million! 👍👍
Sir what are the normal levels for Vitamin B12 ? below than 200 ng/ml B12 level, is it considered normal or low ?
For optimal health, it should be atleast 500,some people feel symptoms even in 300 to 400 range. Below 200 is very low. In Japan minimum is 500.
what about microcytic anemia ? what is it and what cause it ? for mcv below 70-80 , thanks
I have discussed most of these causes in other videos in my “hematology” playlist.
These include:
- iron deficiency anemia.
- anemia of chronic disease.
- sideroblastic anemia.
- Thalassemia.
Each one of these is a video (or more) that I already did.
Colorfully explained woowwwww ..thank you so much😊
Thanks, dear :)
what's the underlying path of glossitis and lemon yellow skin?
Good question, tell us if you looked it up :)
according to some studies, b12 stores deplete after 6 months.
I got some lad work it’s showing my b12 is 377 and in the ranges says ppl with 400 less experienced symptoms. I been loosing hair my hand and feet get numb and cold , I have Poor circulation what should I do
are you vegan?
You should start supplementing according to your symptoms. If you are vegan, then you have to either change diet or take supplement, if you are taking non veg frequently, still symptoms, then you have difficulties in absorbing b12 from food , in that case you need injections. Serum b12 tests are not reliable. We should always look for symptoms and try to treat them. It's true some people feel symptoms even in 400 level and some don't even in 200 range. The only way is supplementing and seeing whether you feel better, this is what I did. I am on b12 injections. Along with this you also need to take folate in order to process b12, they both work together.
I think giving only folate in case of B12 can actually cause some permanent neurological damage
elaborate?
@rses916 its because folate intake without adequate b12 intake can mask b12 deficiency symptoms.
So i watched more than 25 lectures of this playlist only today😢tomorrow is my exam
I wish you success!
Sometimes when I eat meat it feels like I am not digesting it properly. I am suffering slot from either B12 or B6. I feeling very bad. Tired, bloated, dry skin, esp scalp, esp. I feel like there is something above my navel. I feel thirsty, I lost glow on my face and much more..
Have you gone to the doctor?
are you vegan?
@@bekind664 Yeah, every thing seems look all right.
No, I am not.
"they will get divorce" XD
+Sheena Marie Tubiano :)
Sheena you are medical student
You're Indonesian?
What are the neurological side effects ?
Peripheral neuropathy is the most common.
Also subacute combined degeneration of the spinal cord, as well as dementia.
Doctor b12 also helps in lumbar canal stenosis??
you're the best thanks a lot
My pleasure 😇
Thanks Dr Mcdreamy!
Haha 😂
Vitamin B12 stored in the liver for YEAAAARS
Is it really so?
After 2 months of veganism the B12 dropped bellow 200, how could be stored if it's highly needed for homocystein processes?
Perfect*__*
Thank you very much 🌸
My pleasure 😇
my god.... Every commercial is from headspace... and its making me lose my mind...
Hi, would you help me clarify if this anemia is or not hyperchromatic? In italian wikipedia page it says: "it used to be called hyperchromatic anemia" and one of my professors wants to hear "hyperchromatic" during the exam but i'm not sure :/
There is no such thing as hyperchromatic or hyperchromic anemia...It’s self-contradictory!
Why would it be self-contradictory? You could have less RBCs (anemia) but the ones present could be very pigmented (I don't know any condition but logically it's possible).
Check Harrison’s internal Medicine...It states that clearly; when RBCs acquire more hemoglobin, they become larger, not darker! I am also aware that Robbin’s pathology still uses the term hyperchromic!
Explaination is good
Cobalamin and R-protein divorce 😂😂😂
Best bit is when he said the strict vegan alcoholic ate sushi.
Loved it!
Thank you so much 😊
what is this lemon yellow skin? Is it jaundice. Both folic deficiency and B12 deficiency lead to big blood cells, which will be break down by the macrophage. Does this leads to jaundice?
never mind. I believe lemon skin is caused by decreased Hgb and jaundice. pallor+jaundice probably will be yellow. Don't know what skin color change will happen in Asian people. We are born yellow.
sir my blood count is 10 and mcv is 127 plz recomend treatment age is 33 years i eat B12 and folic acid cap but no any change
What do you mean by blood count?
His haemoglobin might be 10
Take injections of b12