I have a friend with EDS who is also an ambulatory wheelchair user. Seeing what they have to manage every day is, to put it real lightly; humbling. I have Fibromyalgia and CFS myself, and we both look out for eachother whenever we are together, but I cannot ever imagine what it is like to have to go through what you guys and my friend have to go through. Nobody is ever worse than the other, thats the chronic illness rule of thumb. But EDS is seriously one of the most unfair illnesses I have ever witnessed. Keep fighting that good fight guys! Y’all are stupidly amazing and incredible at coping with your illness, and maybe one day in the far future, we can find even better management for ALL chronic illnesses the more awareness we spread! ❤❤
If ur panicking about Brain-Eating Amoeba, this will help: 1. It’s only found in subtropical climates or hotter. 2. You won’t typically find it in moving water. It’s only found in still water. 3. It must get really deep in the nose. (Like you will notice when it does) 4. It has to get in the nose without being found by your immune system. (20 % chance) 5. It can’t be found in tap water if you live in an area with proper sanitation. 6. Just don’t swim in lakes bruh, swimming pools were invented for a reason.
About that, it would ALSO have to find acetylcholine, so even if it got into your nose and wasn't caught by the immune system, it still might do nothing. Acetylcholine attracts eukaryotic cells, typically used to signal immune cells. Amoeba are eukaryotic, and they have also been found to have receptors for acetylcholine. So the odds are kinda in your favor with this one :3
Actually it can be found in swimming pools, especially ones that are used by too many humans, your best chance is just swimming in a private pool or swimming in a lake with flowing clean water
As someone with pretty severe eds, I absolutely love the way you explained it. "Sitting on the couch too vigorously" is indeed a thing you can do. Wish you'd talked about the other symptoms, though, as it affects the whole body. Nasty menstrual cramps, digestive problems, scoliosis, fatigue, and heart problems, to name a few. It does indeed suck ass.
The way EDS affects everything is the real problem with our syndrome. Collagen makes up everything and is falling apart, seemingly stuck together with tape and a dream. It robbed me of my life.
@jmarshal yah, nothing works right, and I hurt all over all the time. It's not fun. I'm only 16, and I'm looking into getting a motorized wheelchair bc I just can't anymore.
@@Protoplanetary_Dust I’m so sorry. It must be hard to have such bad symptoms so early. The pain and other symptoms didn’t really start until I was about 21. I had enough trouble in high school without adding fibro pain and dislocations. I hope you can get a chair. I’d love one, too, as it would give me back a lot of freedom. But they’re so expensive.
@@Protoplanetary_DustI have the hyper mobility type and it’s so fucking bad. I didn’t get diagnosed until I was 11, (my guess is my kidney issues covered up what was going on with me) I remember walking to the table to lay down and my doctor was telling me to stretch out my arms and saying like “Y’know, I think you have a type of a disease called Ehlers-Danlos syndrome.” And now, I’m so close to having to quit gymnastics because of the frequent hyperextensions of my arms. The only sport I’m able to do with no issues is swim. I literally do not think I can handle this any longer, the pain is so unbearable.
Those assassin bugs, really. Really. Really. Hurt. Excruciating. It felt like a white hot wire being thread up my arm. Got bit on the finger, I could feel it in my armpit
@Macachee yep. If you aren't actively holding your shoulders up, then any downward force on your arms (i.e., gravity pulling your arms down while walking) cause them to just... fall out. Sometimes, it's a complete dislocation. Sometimes, it's just a subluxation.
I have been stung by a Cow-killer. I was chilling near a lake in a forest, minding my business, and the little sucker decided to go to my feet and stung me, unprovoked. The pain was unbearable. I screamed for a while, my friends laughed at me thinking I was being a wuss and exaggerating. little did they know I was stung by one of the strongest venoms. it was unbearable for about one hour. After that, it was painful but bearable, just local.
I mentioned this in the server already, but I wanted to thank you again for covering Ehlers-Danlos Syndrome! As someone who has EDS, it means a lot to see more awareness and understanding about it being shared. :)
Yes!! I have a shirt that’s purple with specks of bleach over it, black and white rainbow with a heart at the center with the words “We wear stripes for Ehlers-Danlos Awarness.” I fucking love that shirt so much.
"Every lethal infection!" *goes on to list a bunch of non lethal insect stings, then a bunch of minor every day infections that would require a severely compromised immune system to kill, and a couple infections that will kill like 1 in 1000 healthy people*
Okay? That doesn't mean these every day diseases can't actually kill you. The flu can kill you, people can easily overcome it. Strep throat can kill you, people can easily overcome it. Just because it's easy to treat doesn't mean it's not deadly.
I had strep throat so many times as a toddler/little kid (i legit had to go to the hospital for strep at 3 yrs old) and now im basically immune to strep now. I don't think I've had strep throat since i was 6.
The last time I saw a red velvet ant was when I went to South Carolina, it was crawling across a porch that I was on and near, guess what I did… You still want to know? I did not get stung I flicked it off of the porch that I was on. This is a memory that I will forever remember because it was funny
I had toxoplasmosis once. Lymph nodes swelled to the size of golf balls. Took weeks for them to go back to normal size. Got it from a bad series of cat scratches while giving a flea bath. Besides that i felt fine
You should've combined all of the little "icons" for the title/intro in addition to stringing all of the individual videos together. It would've been cool to see a huge grid of all of them combined.
Not life threatening but another streptococcus disease: Some people who frequently get strep may develop symptoms of obsessive compulsive disorder, called PANDAS. Treatment is basically making sure that you don’t get strep because the symptoms get a million times worse then, and treating the OCD in general.
@@PIZZAdayisback well, uhm, I was referring to why the title says lethal infections, but the first video was about dangerous arthropods, which aren’t diseases last I checked.
The funny part is ive had 4 of the insects as pets and none of them have ever harmed me ive ran into almost every one of them too except a red velvet ant
Fun fact in most intensive care places (to my knowledge) have antivenom other fun fact black widows can be kept as pets, wouldn't recommend it but its on my list of pets i want to own
Damn. I'm terrified of scorpions and knowing there's an EIGHT INCH scorpion out there literally called a "DEATH STALKER"... But its venom is also worth 39 mil per gallon.. Geez. Talk about a dilemma for me. Lol.
there have been at least 3 known survivors of brain-eating amoeba. two recovered and went on to live totally normal lives after rehabilitation and one survived with severe brain damage but is still working on regaining skills now
When I was 4 I got strep throat and almost died because the doctors didn’t believe my mom. I was in the hospital for a month and had to get my tonsils removed
I have under multiple occasions handled and relocated assassin bugs not knowing what they were, thank God my boyfriend informed me of how poisonous and dangerous they are before one decided to retaliate to being moved
So the bombadier farts lighter fluid???? If you put all of these bugs in container, one each, who would come out on top?? Whos the most powerful?? Or would they all eat eachother
So confused right now bc all i saw in the thumbnail was the mention of ehlers danlos...pretty sure that it is definitely not a lethal infection bc i happen to be someone who lives with it...🤔
Nah bro right when I searched up “myasthenia gravis the evaluator” cuz my friend has it and i want to understand it more, it showed up in the video lol
Nightsweat? atleast we get a good workout! Familial Hypercholesterolemia is caused if a piece of fat is grown and that can block Artery Blood Flow which can cause a heart attack. One time i used to get Gongylonema Pulchrum but i just thought i had a sore throat but every gulp and a sip killed me so i drank as much as cold water even though it is deadly for my kidneys then i took tylenol every day and it cured atleast.. Amoebas are celled creatures that are in old abonded pools lakes or rivers and they go up to your nose to your brain and it can be fatal if not treated.
Never pick up centipedes they all have a extremely painful bite but if you see one with a lot more legs and looks like a very big elongated roly poly then it’s a millipede please do pick it up
16:58 rare you say I have it currently and this is my fourth time with it Edit 17:02 ooh close to none you say I'm 16 with a "close to none" of it happinge Guess I'm just unlucky
My dad has been bitten by a amazonian giant centipede and ive been bitten by 20 cow killers at the same time, the bloodline of insect trauma caries on 😀
relatable, i used to get it back to back with the flu every other week for the entirety of a school year. the urgent care ladies started to recognize me at that point (i have a weak immune system and the school didn't focus on cleanliness)
I must have Alzheimer’s because I don’t remember subscribing to the evaluator note that was just a joke. I wanted to be funny because I thought that would be funny. Sorry if that offended you I will actually subscribe I listen to you during a lot of stuff like playing subnautica
I in the medical field and a surgeon.I have done just about everything. Inluding in cwsrung with people. I was working with the Coved with badly infected people. I haye to givepwipld a new lease Abele yo cure people.
Here's a free phonology for a conlang: Consonants (including combos): p d ɡ m r ɲ v s ð dr sr mr pr ɡr vr Vowels: i y ɛ ɑ o u Nasality on vowels indicated by an n (Ie poth vs. ponth) (C³)V(C)(V²)(C) SOV Pro-drop (Ie you're cool vs. are cool) Adjectives after nouns but adverbs before verbs
Join us discord.gg/M8KaA5wcZU
Not related and I know you usually do a vote kinda thing, but could you do a video on every unexplained or unknown space object?
Is 18 hrs early? Yeah it's 1:13
Not me
Me
7:52 PM a at 8:02 PM I can’t join
I already said thanks in the server but thank you for covering Ehlers Danlos! I have EDS and it’s nice to see awareness be spread about it :)
Was just about to comment this! It did make me giggle a little seeing it labelled 'lethal'
AYEEE ZEBRA GANG!! eds itself isn’t lethal, the complications from
faulty connective tissue and its comorbidities is what makes it dangerous
I have a friend with EDS who is also an ambulatory wheelchair user. Seeing what they have to manage every day is, to put it real lightly; humbling. I have Fibromyalgia and CFS myself, and we both look out for eachother whenever we are together, but I cannot ever imagine what it is like to have to go through what you guys and my friend have to go through.
Nobody is ever worse than the other, thats the chronic illness rule of thumb. But EDS is seriously one of the most unfair illnesses I have ever witnessed. Keep fighting that good fight guys! Y’all are stupidly amazing and incredible at coping with your illness, and maybe one day in the far future, we can find even better management for ALL chronic illnesses the more awareness we spread! ❤❤
Yayyy! EDS!
Some forms of eds can be lethal. Specifically, those that affect the heart and blood vessels.
If ur panicking about Brain-Eating Amoeba, this will help:
1. It’s only found in subtropical climates or hotter.
2. You won’t typically find it in moving water. It’s only found in still water.
3. It must get really deep in the nose. (Like you will notice when it does)
4. It has to get in the nose without being found by your immune system. (20 % chance)
5. It can’t be found in tap water if you live in an area with proper sanitation.
6. Just don’t swim in lakes bruh, swimming pools were invented for a reason.
About that, it would ALSO have to find acetylcholine, so even if it got into your nose and wasn't caught by the immune system, it still might do nothing. Acetylcholine attracts eukaryotic cells, typically used to signal immune cells. Amoeba are eukaryotic, and they have also been found to have receptors for acetylcholine. So the odds are kinda in your favor with this one :3
We have them in Ohio. We've had water parks shut down over it here
@@reganstormtail3614 There is your reason. Its Ohio. Of course its there 😂
Actually it can be found in swimming pools, especially ones that are used by too many humans, your best chance is just swimming in a private pool or swimming in a lake with flowing clean water
@@awesomepossum4375ye like a non muddy creek
As someone with pretty severe eds, I absolutely love the way you explained it. "Sitting on the couch too vigorously" is indeed a thing you can do. Wish you'd talked about the other symptoms, though, as it affects the whole body. Nasty menstrual cramps, digestive problems, scoliosis, fatigue, and heart problems, to name a few. It does indeed suck ass.
The way EDS affects everything is the real problem with our syndrome. Collagen makes up everything and is falling apart, seemingly stuck together with tape and a dream. It robbed me of my life.
@jmarshal yah, nothing works right, and I hurt all over all the time. It's not fun. I'm only 16, and I'm looking into getting a motorized wheelchair bc I just can't anymore.
@@Protoplanetary_Dust I’m so sorry. It must be hard to have such bad symptoms so early. The pain and other symptoms didn’t really start until I was about 21. I had enough trouble in high school without adding fibro pain and dislocations. I hope you can get a chair. I’d love one, too, as it would give me back a lot of freedom. But they’re so expensive.
@@Protoplanetary_DustI have the hyper mobility type and it’s so fucking bad. I didn’t get diagnosed until I was 11, (my guess is my kidney issues covered up what was going on with me) I remember walking to the table to lay down and my doctor was telling me to stretch out my arms and saying like “Y’know, I think you have a type of a disease called Ehlers-Danlos syndrome.” And now, I’m so close to having to quit gymnastics because of the frequent hyperextensions of my arms. The only sport I’m able to do with no issues is swim. I literally do not think I can handle this any longer, the pain is so unbearable.
oh man, that sucks :( I have a lot of friends with EDS and it all manifests differently for them- it's such a clusterfuck of a genetic disease
i love the longer videos dude this one great, however idk if the bugs are part of the diseases either way still good
It's a compilation video.
That's what I thought
His point was that bugs aren't infections @TheSpiritombsableye
Those assassin bugs, really. Really. Really. Hurt. Excruciating. It felt like a white hot wire being thread up my arm. Got bit on the finger, I could feel it in my armpit
My dad has ehlers danlos, it’s fascinating but terrifying, his shoulders tend to just fall out sometimes
Lmao saaaame
I have it too 😁
Fall out?
@Macachee yep. If you aren't actively holding your shoulders up, then any downward force on your arms (i.e., gravity pulling your arms down while walking) cause them to just... fall out. Sometimes, it's a complete dislocation. Sometimes, it's just a subluxation.
I have been stung by a Cow-killer.
I was chilling near a lake in a forest, minding my business, and the little sucker decided to go to my feet and stung me, unprovoked.
The pain was unbearable. I screamed for a while, my friends laughed at me thinking I was being a wuss and exaggerating.
little did they know I was stung by one of the strongest venoms.
it was unbearable for about one hour. After that, it was painful but bearable, just local.
Their prob fake friends
Ass-Destruction- had me rolling
I’d like to thank my bf for introducing me to my new favorite adhd white noise videos
1:48 I love how he mentioned Peterson I’ve always wondered how he’d be willing to get stung by anything for a video
I had 8 tonsil infections last year, went to see if i could get my tonsils removed and they said 'You need closer to 9 infections."
*What*
Has that when I was a kid. Doctors are weird.
It took my tonsils being permanently the size of cherries to get to surgery.
I mentioned this in the server already, but I wanted to thank you again for covering Ehlers-Danlos Syndrome! As someone who has EDS, it means a lot to see more awareness and understanding about it being shared. :)
My plague inc pathogen with max symptoms be like:
True
I love how excited everybody with EDS gets whenever it's mentioned lol. I hear hoofbeats...
Hi 🦓
and it’s zebras!
Yes!! I have a shirt that’s purple with specks of bleach over it, black and white rainbow with a heart at the center with the words “We wear stripes for Ehlers-Danlos Awarness.” I fucking love that shirt so much.
We like being included
Hello 👋 🙂↕️
"Every lethal infection!" *goes on to list a bunch of non lethal insect stings, then a bunch of minor every day infections that would require a severely compromised immune system to kill, and a couple infections that will kill like 1 in 1000 healthy people*
Ikr
Me when he said strep throat: 🧐
@@tbh-madsMe when you acted like strep can't actually kill you: 💀
Okay? That doesn't mean these every day diseases can't actually kill you. The flu can kill you, people can easily overcome it. Strep throat can kill you, people can easily overcome it. Just because it's easy to treat doesn't mean it's not deadly.
That moment when you grew up with the metric system, so a foot long is based on the size of a subway sandwich
I had strep throat so many times as a toddler/little kid (i legit had to go to the hospital for strep at 3 yrs old) and now im basically immune to strep now. I don't think I've had strep throat since i was 6.
6:56 they also wear the corpses of dead insects
8:48
Ah a Cazador. Fierce predators of the Mojave.
The last time I saw a red velvet ant was when I went to South Carolina, it was crawling across a porch that I was on and near, guess what I did…
You still want to know?
I did not get stung
I flicked it off of the porch that I was on. This is a memory that I will forever remember because it was funny
0:17 is ridiculous😂
EDS is genetic, not an infection. Some subtypes shorten average lifespan while others do not.
"lethal infection" LOL tf is this
Except what it says.
Sam O’Nella would like his Bombardier beetle Reddit joke back
I had toxoplasmosis once. Lymph nodes swelled to the size of golf balls. Took weeks for them to go back to normal size. Got it from a bad series of cat scratches while giving a flea bath. Besides that i felt fine
Omg ehlers danlos mentioned
Who is early here?
I am
Me
Me
Me! Up to feed my baby and a long one is perfect 😂
Me
I really enjoy the videos, but DUDE the title creates a disonance in my brain i cant get rid of
You're wrong about the bombardier beetle
Sounds like something a bombardier beetle would say
@@pinkcowqueen maybe I am, who knows? :)
Actually it's pronounced /bɑmˈbædiɚ/
(Jk that's not the right transcription in IPA)
An ass destruction
You did the wrong title
someone didnt watch the entire vid
☠️😭
15:18 Lethal company reference
Wrong timestamp buddy 15:22
You should've combined all of the little "icons" for the title/intro in addition to stringing all of the individual videos together. It would've been cool to see a huge grid of all of them combined.
Thank you for enlightenment
Damn, theres always new ways to die every day isnt there
They aren't new ways but I guess yeah
Did you that the Beatles are named after the beat generation (kinda like proto "hippies")
@@PIZZAdayisback you always learn about different ways to die so you could consider it new to yourself
@@Thevioletpyro yeah that makes sense
Cats shouldn't be given milk because their stomachs aren't built for it
@@Thevioletpyroyeah that makes sense
Not life threatening but another streptococcus disease:
Some people who frequently get strep may develop symptoms of obsessive compulsive disorder, called PANDAS. Treatment is basically making sure that you don’t get strep because the symptoms get a million times worse then, and treating the OCD in general.
We really started out with weapon of ass destruction hun? I mean that sets a tone, thats for sure
There was once an assassin bug in Gerald’s home! And in a closed off area in Gerald’s school.
After seeing my grandpa go through dementia, it is probably my biggest fear of getting diagnosed with someday (possibly)
Why was the bug compilation added?
Cuz dangerous=lethal apparently?
@@PIZZAdayisback well, uhm, I was referring to why the title says lethal infections, but the first video was about dangerous arthropods, which aren’t diseases last I checked.
@@XalasiaBall i guess because "every dangerous bug or ailment" wasn't on the list for names
@@PIZZAdayisbackits a mistake. Thats why.
6:20 im never going into tue woods again
The funny part is ive had 4 of the insects as pets and none of them have ever harmed me ive ran into almost every one of them too except a red velvet ant
Fun fact in most intensive care places (to my knowledge) have antivenom other fun fact black widows can be kept as pets, wouldn't recommend it but its on my list of pets i want to own
Damn. I'm terrified of scorpions and knowing there's an EIGHT INCH scorpion out there literally called a "DEATH STALKER"...
But its venom is also worth 39 mil per gallon.. Geez. Talk about a dilemma for me. Lol.
I have Ehlers-Danlos Syndrome! I hate it. I have constant joint pain and my joints are super bendy, causing a lot of injuries and dislocations.
you should really include the executioner wasp, its sting index is much higher then the bullet ant
The bullet ant is the worst sting in the sting index
@@Falloutboyfanatic11 executioner wasp ranked higher then the bullet ant
4:05 as someone with a deathly fear of centipedes, thank you for that✨️
there have been at least 3 known survivors of brain-eating amoeba. two recovered and went on to live totally normal lives after rehabilitation and one survived with severe brain damage but is still working on regaining skills now
These aren’t lethal infections these are dangerous insects with defence
When I was 4 I got strep throat and almost died because the doctors didn’t believe my mom. I was in the hospital for a month and had to get my tonsils removed
As a person whos SCARED of almost very bug i come across, this just made me scared of everything,,, even ants😣
Tarantula hawk wasps aren’t aggressive unless they feel threatened. You can even walk past them, and they won’t do anything.
I have under multiple occasions handled and relocated assassin bugs not knowing what they were, thank God my boyfriend informed me of how poisonous and dangerous they are before one decided to retaliate to being moved
Get the notes! Get the notes!
i have EDS and my skin isn't stretchy but my joints and whatever is holding my bones in place are all screwed up.
r.i.p arthur morgen
So the bombadier farts lighter fluid????
If you put all of these bugs in container, one each, who would come out on top?? Whos the most powerful?? Or would they all eat eachother
8:53 tarantulas cant kill you so their venoms not that bad, I got 5
I was unlucky enough that I got strep over 13 times in 1 year but lucky enough that I didn't have my body attack my fucking organs😭
3:18 FIRE IN THE HOLE
11:25 no they do not get that big, only emperors get that huge. These get 3” max.
So confused right now bc all i saw in the thumbnail was the mention of ehlers danlos...pretty sure that it is definitely not a lethal infection bc i happen to be someone who lives with it...🤔
the emerald cockroache wasp doesn't sound that bad now
this is why i dont fuck with insects. unless i’m 100% sure with what i’m dealing with, i’m not going near it
Nah bro right when I searched up “myasthenia gravis the evaluator” cuz my friend has it and i want to understand it more, it showed up in the video lol
I found an Assassin bug chilling inside my room bruh
Nightsweat? atleast we get a good workout! Familial Hypercholesterolemia is caused if a piece of fat is grown and that can block Artery Blood Flow which can cause a heart attack. One time i used to get Gongylonema Pulchrum but i just thought i had a sore throat but every gulp and a sip killed me so i drank as much as cold water even though it is deadly for my kidneys then i took tylenol every day and it cured atleast.. Amoebas are celled creatures that are in old abonded pools lakes or rivers and they go up to your nose to your brain and it can be fatal if not treated.
15:35 am i the only person who's never caught strep throat before?
I had Strep twice. ONLY A FEW WEEKS APART. IT F*CKING CAME BACK.
Me watching this in bed with strep 😃
Never pick up centipedes they all have a extremely painful bite but if you see one with a lot more legs and looks like a very big elongated roly poly then it’s a millipede please do pick it up
35:37 my GP is referring me to a specialist because I think I have hypermobile- Ehlers danlos
Misleading title... anrd thumbnail
how the hell does evolution give squirrels and lizards jack shit to work with but then gives all the weird bugs lobotomy venom
Wasps sting, they don’t bite
I’m here 21hrs after being posted
Eyyyy EDS!
Never knew that someone can be this early😮
you are!!
Im super early too
@@TheEvaluat0rwoah! Very aggressively said, evaluator.
Bro on the last day of school I found a cow killer in my food luckily I didn't eat it
Combustion chamber? More like combuttion chamber
“Ass destruction”
Lol
huh? 49:08
I have had molten leaded solder drip on my flesh, its not fun
I thought Assassin bugs were kissing bugs?
11:08 I know this none it almost killed me
I'm just kidding i am American😂😂
16:58 rare you say
I have it currently and this is my fourth time with it
Edit 17:02 ooh close to none you say I'm 16 with a "close to none" of it happinge
Guess I'm just unlucky
My dad has been bitten by a amazonian giant centipede and ive been bitten by 20 cow killers at the same time, the bloodline of insect trauma caries on 😀
Some of these aren’t even infections
Make your money dude but man do you have to plug your discord every 5 minutes?
Why is this video called infections if it’s all about bugs
its a combination of a bunch of older videos into one, longer video. one of those videos was "every deadly insect explained".
once I got strep like 4 times in one school year (and I don't even have tonsils)
relatable, i used to get it back to back with the flu every other week for the entirety of a school year. the urgent care ladies started to recognize me at that point (i have a weak immune system and the school didn't focus on cleanliness)
Wait so eds isn't just supposed to be a minor inconvenience you just have to "tough out"? I'm not just being dramatic?
Lady bug isnt a beetle
I must have Alzheimer’s because I don’t remember subscribing to the evaluator note that was just a joke. I wanted to be funny because I thought that would be funny. Sorry if that offended you I will actually subscribe I listen to you during a lot of stuff like playing subnautica
I think he got the videos mixed up
6am is crazy
I in the medical field and a surgeon.I have done just about everything. Inluding in cwsrung with people. I was working with the Coved with badly infected people. I haye to givepwipld a new lease Abele yo cure people.
Me also, I love your vids!
Here's a free phonology for a conlang:
Consonants (including combos):
p d ɡ m r ɲ v s ð dr sr mr pr ɡr vr
Vowels:
i y ɛ ɑ o u
Nasality on vowels indicated by an n
(Ie poth vs. ponth)
(C³)V(C)(V²)(C)
SOV
Pro-drop
(Ie you're cool vs. are cool)
Adjectives after nouns but adverbs before verbs
...eds is not an infection
0:22 BAHAHAHHAHAHAHAHAHHAHAHHAHAHAHAHAH
LMAO the reddit user joke