Catalytic Efficiency of Enzymes (kcat/Km) - Part II

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AK Lectures! I know you may not be having major views at this moment, but the few who are just now are very grateful!// A medicine studying subscriber

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Remli Yusupov Thank you for the kind words! Appreciate the sub! :-)

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Laila Samadi Welcome! thanks for the kind words!

[@rodaf2]

Excellent videos. I sometimes wonder if you get sufficient oxygen for aerobic respiration during these lectures ;). PS: small error at 4:00, you say 'low' Km where you mean 'high' Km (i.e. low affinity). Many thanks for your work!

[@AKLECTURES]

robert fransdonk Thanks Robert! :-) And yes, I meant to say a high Km. I will put in an annotation for that.

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I just want you to know there are many molecular biology students who are very grateful for these videos! THANK YOU! :)

[@Beccastudyingmcat]

The ending of the video really made everything make sense for me. Finally I understand what Km and Kcat mean!

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awsome teacher...

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So many k's but your videos are very eloquent and super useful! Thank you!

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Really excellent a teaching way it is, I will keep going with all u sir this series of lectures,thanks a lot!

[@zero450571]

wonderful explanation, thank you

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Wow. just wow. Thank you for another nail in the coffin.

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Thank you! Very clear and to the point.

[@shaliniks7453]

Very nice explanation....

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great lecture! thank you so much!

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Awesome. I get it now.

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Beautiful!

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Thanks a lot.

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Thank you so much!!

[@Sunshine-zi7oy]

thank you so much sir

[@samvedkulkarni4705]

I had a doubt, we assume that low km means high affinity between substrate and enzyme on the condition that k-1>>>>>kcat. But at the end we are saying that low k-1 will lead to high catalytic efficiency of enzyme. I am confused. Please help 😊

[@areebfatima8125]

i think even under the first consideration the enzyme efficiency still revolves around lower K-1 value i.e lower the k-1 value lesser will be the dissociation of ES into E and S and lower is the Km value.

[@rawanrhamarsheh1718]

No need for a further studying or repeating after that ! :))

[@mjxvmaaren67]

7:58, Brownian Motion strikes again lads!

[@AK-di4rv]

Kcat/Km at 1:50

[@TheReck12]

Just got out of my final and was trying to visualize this board, I fucked up and thought km/kcat measured efficiency instead smh

[@AKLECTURES]

Hopefully you still did great!