Sarilumab for Relapse of Polymyalgia Rheumatica | NEJM

More than half of patients with polymyalgia rheumatica have a relapse during glucocorticoid taper. The monoclonal antibody sarilumab offers a novel treatment option.
New research findings are summarized in this short video.
To see the full article, follow this link: nej.md/3rGq5en

[@DrAlexVasquezICHNFM]

Yes, so wonderful. They exchanged one problem for another, and the patients couldn’t tolerate treatment. Very strategic how they measured CRP, when basically providing a CRP antagonist thereby guaranteeing positive results in that analysis.

[@TheLearnMedicineShow]

A nice visual summary. Thanks 👍🙂

[@heidischulze4057]

Why do I want to increase my chance for neutropenia when that is the major downside to prednisone? Why increase my risk of permanent damage?

[@zootybeano]

I have diverticulitis so would never take it. I dont have a rheumatologist anyway so it's a moot point.