The Key Biomarkers to Measure With a Blood Test | Dr. Casey Means & Dr. Andrew Huberman

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  • Опубліковано 3 лис 2024

КОМЕНТАРІ • 166

  • @HubermanLabClips
    @HubermanLabClips  Місяць тому +14

    This clip is from the Huberman Lab episode "Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation". The full episode can be found on UA-cam here: ua-cam.com/video/8qaBpM73NSk/v-deo.html

    • @dattebenforcer
      @dattebenforcer Місяць тому

      How do you spell all those tests she mentioned?

  • @520cuban
    @520cuban Місяць тому +174

    1)Hemoglobin A1C
    2)Triglycerides
    3)Vitamin D
    4)Homocysteine
    5) TSH
    6) Free T-3
    7) Ferritin
    Outside a CBC/Differentials
    Comprehensive Metabolic panel
    The above seven markers provide a picture of Metabolic, Immune, and Inflammation

    • @amya9597
      @amya9597 Місяць тому +3

      Thank you!!!!

    • @elinino5275
      @elinino5275 Місяць тому +10

      Inflammation marker is C-reaction protein

    • @520cuban
      @520cuban Місяць тому +7

      That's correct, however if I was only able to use 7 biomarkers, Ferritin not only predict inflammation, but also shows Iron storage in the liver which gives me a picture of Iron status.

    • @sharifuzzamanshakel9530
      @sharifuzzamanshakel9530 Місяць тому

      Thank you 🙏

    • @alanasky7406
      @alanasky7406 Місяць тому

      ​@@520cuban Thank you so much! 💕

  • @phylodude
    @phylodude 14 днів тому +6

    She is a perfect teacher. I'm a trained geneticist and molecular biologist and she nails it in a way I could never explain. Bravo!

  • @juangiordana
    @juangiordana Місяць тому +51

    The key biomarkers to measure with a blood test are:
    - Fasting glucose
    - Fasting triglycerides
    - HDL cholesterol
    - Hemoglobin A1C
    - Total cholesterol
    - Waist circumference
    - Blood pressure

    • @hof5943
      @hof5943 27 днів тому

      Can blood test show waist circumference?

  • @poolmilethirty2859
    @poolmilethirty2859 Місяць тому +18

    Thank you, Dr. Means for the explanation, and Dr Huberman for having her elaborate on the biomarkers to understand them better.

  • @kestertan3372
    @kestertan3372 Місяць тому +15

    Optimal range - 3.15
    Fasting glucose - Less than 100
    Triglyceride - Less than 150
    HDL > 40 for men, > 50 for women
    Hemoglobin A1C - less than 5.7%
    Total cholesterol to HDL ratio - less than 3.5 - 1
    Waist size ratio less than 35 Inches for women, 40 Inches for men
    Blood pressure less than 120/80

    • @mikekarr2920
      @mikekarr2920 19 днів тому +1

      Man it’s so hard to get my systolic blood pressure below or at 120. It’s usually 125-135.

  • @DENDENmusicboy
    @DENDENmusicboy Місяць тому +9

    Hubes is so good at acknowledging the flaws of a subject it's actually inspiring

  • @rayharrison6234
    @rayharrison6234 Місяць тому +11

    One I always ask for is C-Reactive Protein (CRP) to measure for inflammation

  • @Me-lj1rk
    @Me-lj1rk Місяць тому +8

    Brilliant...just need to listen over and over...She got on track around 8 minutes...good stuff

    • @TheTale28
      @TheTale28 Місяць тому

      I think so too , sounds clearer from 8 min

  • @mcgdoc9546
    @mcgdoc9546 Місяць тому +17

    The Fasting Insulin levels are critical information. I am surprised that she missed it!

    • @bradtozier6776
      @bradtozier6776 Місяць тому +4

      Ditto. And an hs-CRP.

    • @tigerrx7
      @tigerrx7 29 днів тому +1

      Not just the level. We need to start taking our own insulin levels throughout the day to get a better reading on how the body reacts to food intake. Meaning:
      1. Fasting insulin level
      2. Eat breakfast/lunch
      3. Take insulin level
      4. Take insulin level again after 2-3 hours.
      This shows how well your body manages the glucose intake

  • @him-hk7ii
    @him-hk7ii Місяць тому +7

    She is a role model to future doctors

  • @TheRealSamuiWebcam
    @TheRealSamuiWebcam 11 днів тому

    I test these every 3 months.
    Fasting Glucose
    Fasting Insulin
    Lipid Profile
    Thyroid Panel
    CBC
    Kidney Function
    Liver Function
    PSA
    Hemoglobin A1C
    Ferritin
    Uric Acid
    Homocysteine
    Electrolyte Panel
    Testosterone/E2

  • @jimsgardenproject3507
    @jimsgardenproject3507 Місяць тому +6

    If everyone knew this information the medical system would go broke. So when you really think about it we’re kept in the dark about health as with a lot of other things in life. Notice how defensive people get when you educate yourself and start conversations that push back? Could be health, politics, work methods you name it. How often am I told “well, you’re not a doctor”. I love it. It’s actually a person telling me I wasn’t supposed to learn this stuff. It’s only for doctors to know. I guess im not allowed to get smart? Well tough. They don’t own the market on learning about health. Actually the more I know about health, the easier it is for my doctor to help me when I have a real problem. When I visit my doctor now he simple asks what labs I’d like done for this visit. He may ask why I want something done or suggest it’s not really necessary but I generally get the labs done that I’d like to review for myself. Doesn’t mean I won’t get a message like “you should be on a statin”. That’s his job to suggest that info. It’s my decision whether or not to go with it. How do I know this. Education!

  • @AquarianMan
    @AquarianMan Місяць тому +2

    key biomarkers to measure with a blood test are:
    for metabolic syndrome :
    - Fasting glucose
    - Fasting triglycerides
    - HDL cholesterol
    - Hemoglobin A1C
    - Total cholesterol
    - Waist circumference
    - Blood pressure

  • @eliang87
    @eliang87 Місяць тому +2

    If you read her book. She list different ranges in her book. What she actually believes is optimal to axe metabolic dysfunction

  • @dennispo4998
    @dennispo4998 Місяць тому +16

    Kinda disagree with using waist circumference! Two men (one is 6'3", the other is 5'6") both having 38" waistlines propels you to a whole different universe! Might be better to use a height to waist ratio?

    • @bradtozier6776
      @bradtozier6776 Місяць тому +2

      Yes. Much better.

    • @user-kh8bp6ue8y
      @user-kh8bp6ue8y Місяць тому +2

      I know right?! I keep saying this!

    • @rossb4802
      @rossb4802 Місяць тому +3

      The best marker is to use a waist to hip ratio. Far more reliable than others.

    • @davidflorez1196
      @davidflorez1196 Місяць тому +1

      I agree the formula should be adjusted to height

    • @shinnpt
      @shinnpt 3 дні тому

      @@rossb4802correct

  • @johngomez7118
    @johngomez7118 Місяць тому +35

    The key biomarkers for metabolic health and identifying metabolic syndrome that can be procured in an annual physical:
    1. Fasting glucose
    2. Fasting triglycerides
    3. HDL Cholesterol
    4. Total Cholesterol
    5. HgbA1C
    6. Waist circumference
    7. Blood pressure

    • @kaihubbard4450
      @kaihubbard4450 Місяць тому +14

      If the following things are in these ranges, and you’re not on medication for blood sugar or blood pressure, you are considered optimally metabolically healthy.
      1. Fasting glucose
      50 (women)
      4. Total cholesterol / HDL ratio
      < 3.5 / 1
      5. HgbA1C
      < 5.7%
      6. Waste circumference
      < 35 in (women), < 40 in (men)
      7. Blood pressure
      < 120 / 80
      Dr. Casey says these are easy to change in 1-2 months with lifestyle habits.
      If fasting triglycerides >150, probably b/c of excess carbohydrate intake.
      If fasting glucose >100, probably b/c of excess carbohydrate intake.
      If HgbA1C >5.7%, probably b/c of excess carbohydrate intake on average over the last 90-100 days.
      If blood pressure > 120 / 80, probably caused by not enough nitric oxide activity caused by insulin resistance caused by excess carbohydrate intake.

    • @rollingrock4759
      @rollingrock4759 Місяць тому

      @@kaihubbard4450thank you!

    • @poolmilethirty2859
      @poolmilethirty2859 Місяць тому

      Thank you so much for the summary you saved me the time of having to watch it again to write it down. I pass on all except the waist circumference. ​@@kaihubbard4450

  • @2023Red
    @2023Red Місяць тому

    Yes. Getting the labs is needed. And, it is essential the patient digest the information.

  • @Dr_Boult
    @Dr_Boult Місяць тому +6

    Cannot belive they did not include fasting insulin. Why try to guess if IR is an issue from the rmarkes -- measure it. I pay < $20 for that test and I wish I had know about it years ago before my FG and TG started to creep up.

    • @gayeroyal8870
      @gayeroyal8870 Місяць тому +1

      True. I'm hoping that she covered it in the full episode. I think that the ones she covered in this "clip" were the ones that the docs wouldn't complain about ordering. They usually balk at running a fasting insulin test. To me it is SO important to know and can tell you SO much.

  • @LHMH148
    @LHMH148 Місяць тому +1

    I listen to more of your videos now that’s they’re not over 40
    Mins!

  • @dandrada1
    @dandrada1 Місяць тому +1

    At 1:30, huberman admits his audience wants a little more time for explanation and not just a list of biomarkers.
    Early on, he gave you a heads up that this clip would not just be a list.

  • @THERESAPreston-tc7nw
    @THERESAPreston-tc7nw Місяць тому

    Wow your right all these things tell slot about your health and I wo der hiw many Dr s are missing the important ones?

  • @bobmesserschmidt2078
    @bobmesserschmidt2078 Місяць тому +1

    it's worth pointing out that HbA1c - glycated (aka glycosylated) hemoglobin. Hemoglobin is _inside_ the red blood cells and has nothing to do with slipperiness of the red blood cells.

  • @drsvs
    @drsvs Місяць тому +21

    She left out fasting insulin, the first marker to go up in insulin resistance. Total cholesterol is meaningless. Think about it: TC goes up as HDL goes up.

    • @zenrand688
      @zenrand688 Місяць тому

      Right - fasting glucose is not all that helpful - insulin is much better.

    • @arielphillips8484
      @arielphillips8484 Місяць тому +4

      She didn’t say total cholesterol. She said the ratio of total over HDL

    • @dirtyharry2534
      @dirtyharry2534 Місяць тому +5

      Although, the triglyceride:HDL ratio is a good proxy for insulin resistance.

    • @zenrand688
      @zenrand688 Місяць тому +1

      @@dirtyharry2534 Interesting - I hadn’t heard of that. Where can I find out more about that? thx

    • @dirtyharry2534
      @dirtyharry2534 Місяць тому

      ​@@zenrand688 Dr. Paul Mason is one that covers this subject well. Try his presentation, "Blood tests on a ketogenic diet" (Low Carb Down Under channel). Dr. Ford Brewer discusses this ratio. Dr. Ekberg has a couple of good videos where he analyzes a patient's cholesterol results in detail. I've encountered others, but these ought to be a decent start.

  • @smitasathe3561
    @smitasathe3561 23 дні тому

    I have mild hypertension and am on medication. I am vegetarian, very particular about diet and exercise at least 4-5 times a week. All my other numbers are in range. It is just bp and i am unable to bring it down without mefication.

  • @YTSparty
    @YTSparty Місяць тому +1

    What about Fasting Insulin? Paul Saladino MD suggest we get a fasting insuling blood test.

    • @ankitg6454
      @ankitg6454 26 днів тому

      Paul Saladin the original charlatan

  • @suryaraj7645
    @suryaraj7645 Місяць тому +1

    Hi, what happens to the sugars, carbs, /triglycerides when you take statins ? How exactly do statins reduce cholesterol values even when you consume carbs /sugar? 🤨

  • @jayachandranthampi4807
    @jayachandranthampi4807 Місяць тому

    Interesting that we know ourselves from "Response / Reaction", like what's being circulated within. Ofcourse, it's the best available now, especially the fasting numbers. However, like the Schrodinger cat, the measurement could influence - means, we are measuring only what we want to know & not necessarily the full picture within. Ie, if I am paying my loan instalments properly, then I am good (I might be stealing or looting to pay). It need not tell me my capacity to face a challenge. Example: how good am I in actual "combat / stress / challenge". Like a Treadmill test, the numbers must show me my capability in combat, than when I am rested. That's a better indicator of "Health", especially "Active health". Current numbers are "Disease" finding than an actual Health statement. It's like seeing a picture of river, where as it's dynamic in reality. Health & numbers must thus be linked to other factors (futuristic) like social (mental) expression, familial conditions etc etc. An individual is actually a Group, networked reality. We need to account for the "Randomness". History based is seldom the future. We need to know Destiny than Fate, while dealing with Health & recommendation must be futuristic than history solving. Probabilities based of multiple factors are to be included as part of score & assessment. Example: ability to balance, ability to get up without support, from a floor sitting posture, HRV scores, etc etc. AI used measures are future than these crude numbers, as far as Health is concerned (not Disease). It's like "Credit score". Even things like O2 saturation at work, lung function numbers etc shows how we are at work (challenge) than at rest.

  • @mkmccoy6929
    @mkmccoy6929 Місяць тому +2

    T3 , t4 , iron, hemoglobin , vitamin D , B vitamins ... And testosterone .. would be where I'd start .... Your hormones control everything ..

  • @jeagr209
    @jeagr209 Місяць тому +10

    You interrupted her and she never got to the other tests.

  • @StarvingMyselfToLIFE
    @StarvingMyselfToLIFE Місяць тому

    Does gluconeogenesis and depletion of glycogen stores increase/spike blood sugar?

  • @janoscsato2124
    @janoscsato2124 Місяць тому +1

    numerical value numbers without dimensions are not good at all ! e.g. tryglicerids are for me shown in mmol/liter, and the limit number mentioned 150 must be rather in milligrams per deciliter

  • @Kartikkashyap8796
    @Kartikkashyap8796 Місяць тому +8

    He : Why do you talk like that
    She : it's my voice
    He : No it's not, it's a affectation😂😂

  • @nohasamir3134
    @nohasamir3134 Місяць тому +1

    What if I'm prediabetic and have low triglycerides? What does it mean?

    • @sobatjalanseru
      @sobatjalanseru Місяць тому

      @nohasamir3134, maybe because too much fructose in your body, you may listen to dr Robert Lustig interview with dr dom d’agostino, the title how to avoid insulin resistance and why its important, they discuss about a guy name sami inkinen who is thriatlon athlete and work out 5 hours a day but got pre diabetes because of fructose

  • @Steve-nb9kg
    @Steve-nb9kg Місяць тому +2

    Yeah this is complex all of my markers are well within range but my CAC score is 3000! Trying to figure this out.

    • @andrewrivera4029
      @andrewrivera4029 Місяць тому

      Go 0 carb immediately.

    • @bradtozier6776
      @bradtozier6776 Місяць тому +1

      Yes. What Andrew said. Also, you won't get a full picture unless you know what you're Fasting Insulin is. Even then, a couple of others could be helpful to know.
      But yeah, carnivore for sure.

  • @alexi2460
    @alexi2460 Місяць тому

    Good to send out to friends and family

  • @ReeInvesting
    @ReeInvesting Місяць тому

    love it all!

  • @cmyoutuber1289
    @cmyoutuber1289 13 днів тому

    How does one raise HDL to optimal levels within 1-2 months 😅

  • @dennispo4998
    @dennispo4998 Місяць тому

    Casey's awesome!!!

  • @quisge
    @quisge Місяць тому +1

    Did she just hint at the Randle Cycle without calling it out by name? Why I think she did!

  • @abhi123nav1
    @abhi123nav1 Місяць тому +9

    Can somebody write the biomarkers in the comments and their optimal levels?

    • @WeighedWilson
      @WeighedWilson Місяць тому +6

      Yes *you* can

    • @andrewrivera4029
      @andrewrivera4029 Місяць тому +4

      Go 0 carb, exercise, get outside in the sun and lower stress through sleep then you don’t have to worry about the tests.

    • @EdwardsNH
      @EdwardsNH Місяць тому

      @@andrewrivera4029 Please don't go zero carb. Personal trainer/dietician/nurse. Processed carbs, sure. If you can, that's wonderful. But don't eliminate fruits and vegetables
      Plus, you can do everything perfectly, and still have issues. This is a very ignorant comment

  • @peterfialka5315
    @peterfialka5315 Місяць тому +1

    I understand it’s a short version of a longer conversation but we got sidetracked by triglycerides and fasting glucose for the eternity. While no time was used to clear up the ApoB nor LDL

  • @deborahcollins6983
    @deborahcollins6983 Місяць тому +1

    I can’t believe you didn’t mention fasting insulin! Wow! Hyperinsulinemia is the driver of all metabolic diseases!

  • @SSquared60
    @SSquared60 Місяць тому

    She says these tests are very inexpensive if run outside the doctors office. And where might that be. If I look at questions or Labcorp it’s very expensive.

    • @LHMH148
      @LHMH148 Місяць тому

      Expensive compared to what ???

    • @SSquared60
      @SSquared60 Місяць тому

      @LHMH148 not sure what your point is in this strange question.

    • @twillafaye515
      @twillafaye515 Місяць тому

      Not for illegal immigrants

  • @sialee5926
    @sialee5926 Місяць тому

    HDL is it 50 for women, or above 50?

  • @shawnmcgrath3226
    @shawnmcgrath3226 Місяць тому +2

    Nobody is getting there triglycerides in the 50s. Maybe a tiny , tiny percentage. 60-70 in my opinion is optimal ..

  • @wSpaceArt
    @wSpaceArt Місяць тому

    Myleoperoxidase, MPO

  • @prassrid
    @prassrid Місяць тому +2

    Fasting Insulin is THE most important and key blood marker which provides a clear picture of metabolic Health.
    Why did they miss this?!
    at 1:40 , she mentions the reason is choosing these because vast majority of metabolically unhealthy people use these parameters based on some studies over past 5 years.
    To me, it does not make sense to use parameters , just because most of unhealthy Americans have used them. Meh! Lousy method!
    Of course, these parameters also are good to know about health, but, 'Fasting Insulin' levels indicates ones health level more incisively; also, one should be aware of 'correct range' within which it (Fasting Insulin) must be ( not the medical industry touted vast ranges)

    • @davidflorez1196
      @davidflorez1196 Місяць тому

      What's the difference between tryglicerides/HDL ratio or just tryglicerides and fasting insulin?, can someone with low tryglicerides '50' be insulin resistant?

  • @stefanocasali9739
    @stefanocasali9739 Місяць тому +2

    Ok, thanks. But still, at this point I believe that the community needs a more nuanced, mechanistically clear framework for understanding this kind of topics. I don’t want to sound tedious or anything, but: it’s boringly obvious that having fasting glucose AND fasting triglycerides in the “high normal” range is not good. Let’s try to address different scenarios; for example, what about slightly elevated fasting glucose AND normal / low triglycerides? How to interpret this type of situation? This is just an example, of course. We need tools and ultimately a framework for understanding THIS type of scenarios.

  • @UmeshMahalingaiah
    @UmeshMahalingaiah Місяць тому +1

    Ok

  • @stuartmalin661
    @stuartmalin661 Місяць тому

    I so disagree with her about fasting glucose. I am Carnivore, and my *highest* glucose measure of a day can be my morning fasting, because that is after my liver produces glucose in order for me to start my day. I'd say that: (1) highest glucose of the day is more important - which for me can be 120, and (2) focus on insulin levels, not glucose.

    • @LHMH148
      @LHMH148 Місяць тому

      Yes she talks about that too and in her book

  • @tomharvey5466
    @tomharvey5466 Місяць тому

    Fasting insulin

  • @Aviation_Professional
    @Aviation_Professional Місяць тому +1

    STAY AWAY from Doctors folks. Work hard at you're lifestyle and diet. Buy your tests online cheaply. I run her labs for about $75

    • @1treyton1
      @1treyton1 Місяць тому

      Telling people to stay away from doctors and you used the wrong "your." That's not very credible.

  • @Ematuresco
    @Ematuresco Місяць тому +3

    She talks with vocal fry. Room for creeEEAaam ? :D

    • @Periwinkleblue.
      @Periwinkleblue. Місяць тому

      Love her. But the fry grates my soul....

  • @Joseph1NJ
    @Joseph1NJ Місяць тому +4

    I don't see why HDL is relevant. We know low HDL is NOT harmful. We also know high HDL is NOT protective.

    • @SachinPatelDC
      @SachinPatelDC Місяць тому +1

      High HDL can indicate autoimmunity.

    • @slofty
      @slofty 2 дні тому

      @@SachinPatelDC Through what means?

  • @jamesgordon8867
    @jamesgordon8867 Місяць тому

    Want lower A1C? Photobiomodulation

  • @scottj719
    @scottj719 Місяць тому

    8:12 amd they will say, lets check you back here in a year

  • @camilledefreitas6818
    @camilledefreitas6818 Місяць тому

    We never heard what the rest of the blood test she would recommend…..

  • @stoenchu122
    @stoenchu122 Місяць тому

    Fasting Insulin

  • @maryvicente3692
    @maryvicente3692 Місяць тому +1

    You can order Nutrition Genome yourself, don’t need a doctor. $359

  • @angelbianchi4786
    @angelbianchi4786 7 днів тому

    All military service people, police, firefighters, and the alike should HAVE TO BE optimally metabolically healthy before they can join...

  • @northcotemallory9968
    @northcotemallory9968 Місяць тому +2

    He asks for a reminder of what HbA1C is at 4:24. The answer is at 9:05. WAY, WAY too much talking.

  • @Maverik1304
    @Maverik1304 Місяць тому

    First they keep decreasing the top range of everything to sell more medicines over the years & now even within the range is an issue if near the top..fear sells fosho !! 😅

  • @VicDamoneJr82
    @VicDamoneJr82 Місяць тому +3

    i heard if you have a high LDL its actually healthy since its transporting more fats

    • @JakeRichardsong
      @JakeRichardsong Місяць тому

      Source?

    • @dirtyharry2534
      @dirtyharry2534 Місяць тому +2

      It’s only healthy if you also have a low triglyceride:HDL ratio. If not, the LDL is dysfunctional and also getting stuck in blood vessels.

  • @iorch82
    @iorch82 Місяць тому +1

    She missed uric acid.

  • @Ul-zs3vp
    @Ul-zs3vp Місяць тому

    My triglycerides are at 40. Not being sarcastic at all, but is that too low?

  • @akahodgins
    @akahodgins Місяць тому

    ❤❤❤

  • @lorrainefiguereo6354
    @lorrainefiguereo6354 Місяць тому +5

    Dr. Casey Means needs to work on better explaining in simpler way the specific blood test we have to request. I think that this guest was not informative at all. I usually enjoy your video but not this one. Sorry.

  • @ipgvids
    @ipgvids Місяць тому +55

    When you said that your audience hates this, you were not kidding. You literally turned what should have been a ninety second video into eleven minutes and twenty nine seconds. Why do you keep doing this?!?!?!?! It's reached the point where I rarely watch your videos to the end.

    • @Leonardokite
      @Leonardokite Місяць тому +51

      Make your own videos.... maybe you can be a star.

    • @eamonnw
      @eamonnw Місяць тому +7

      a health video that actually wants to steal 10 minutes of your life to get some $$

    • @standUpForTurtles
      @standUpForTurtles Місяць тому +26

      Maybe the best answer for you is to not even start watching them

    • @hfislwpa
      @hfislwpa Місяць тому

      @@eamonnwits a 3 hour podcast filled with amazing knowledge FOR FREE. Some of us love the depth. Not everything needs to be a tik tok video

    • @ignaspan
      @ignaspan Місяць тому +32

      How are you going to explain these biomarkers in 90 seconds?
      I don’t want a list of biomarkers, I want to know what they mean. Also, I would like to see an even longer video with scientific analysis to make sure it’s not just an “opinion”. A mere list of biomarkers doesn’t give any confidence to apply this information in my life.

  • @soheilaabyane6453
    @soheilaabyane6453 Місяць тому

    I am sorry she is so inaccurate. The first question to b e asked is " How old is the patient?"

  • @sparky2390
    @sparky2390 Місяць тому

    I hate Andrew Huberman

  • @jorgeferreiro9783
    @jorgeferreiro9783 Місяць тому +1

    Some errors in what she said. Per UNC study of Araujo et al the optimal waist size in men was less than 40 inches not less than 35 inches as she said.

    • @Bombyton
      @Bombyton Місяць тому +5

      relisten to it. That's what she said, less than 35 for women and less than 40 for men

    • @ελευθερία-ε2ο
      @ελευθερία-ε2ο 25 днів тому +1

      She did say 40, pay attention