Five steps for getting started with bioinformatics

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  • Опубліковано 4 лип 2024
  • This video answers a question I often get on this channel, namely "bioinformatics sounds great, but how do I actually get started with it?"
    Links:
    * Colab: colab.research.google.com/not...
    * Ben Langmead's UA-cam channel: / benlangmead
    * Statistics on Khan Academy: www.khanacademy.org/math/stat...
    * My bash videos:
    - "Introduction to bash for data analysis": • Introduction to bash f...
    - "How to write a bash script": • How to write a bash sc...
    - "How to turn a python script into a command-line program" • How to turn a python s...
  • Наука та технологія

КОМЕНТАРІ • 261

  • @dominic2446
    @dominic2446 3 роки тому +143

    5 steps
    1:34 learn python
    4:05 do courses
    5:27 statistics
    7:38 command line
    9:03 science

    • @elijah1110
      @elijah1110 3 роки тому +2

      Thanks :)

    • @SwapnilJha
      @SwapnilJha 2 роки тому +1

      Thanks mate

    • @2v_32
      @2v_32 2 роки тому +3

      Learn R programming language ....😶

  • @dami5072
    @dami5072 5 днів тому +2

    Thank you so much for linking these steps together and how data in bioinformatics helps to reveal bigger truths in biology. Excited to read more papers in my field.

  • @tallon3925
    @tallon3925 4 роки тому +154

    Yes you’re back! You’ve been a big reason why I’m a PhD student studying bioinformatics.

    • @schakaravarthy6244
      @schakaravarthy6244 4 роки тому

      I want to join PhD can suggest best place for doing PhD

    • @arunbioinformatician2231
      @arunbioinformatician2231 3 роки тому +1

      @@schakaravarthy6244 that's nice to here in which field u r doing PhD

    • @arunbioinformatician2231
      @arunbioinformatician2231 3 роки тому +1

      @@schakaravarthy6244 because I'm also doing phd

    • @schakaravarthy6244
      @schakaravarthy6244 3 роки тому +1

      @@arunbioinformatician2231 No I'm just now completed my masters in bioinformatics I wanna do PhD in Bioinformatics can you suggest me a better place to do that

    • @StatusixinKirubhakaran
      @StatusixinKirubhakaran 3 роки тому +1

      @@arunbioinformatician2231 Hi Arun, I'm studying B.tech in Biotechnology, with Python and C programming knowledge. Can I get a job as a Bioinformatician?

  • @angezoclanclounon1751
    @angezoclanclounon1751 4 роки тому +13

    Thanks a lot. I am a PhD Student working on plant genome assembly and annotation. Your video is very hepfull for me. I have no background in bioinformatics. So I struggle a lot. "Learning by doing" in South Korea. No help..no support...It is very hard. But I keep going. UA-cam, github, and R plateforms help me a lot. Thanks again

  • @Chaosdude341
    @Chaosdude341 4 роки тому +17

    Thanks for coming back! Good to see you're uploading again.

  • @jimgodsey2940
    @jimgodsey2940 3 роки тому

    Maria, thanks for coming back. Your videos are outstanding and I am sure everyone wanting to learn more about BFx is thrilled you are creating videos again. Thanks for the links!

  • @Webigbie
    @Webigbie 4 роки тому +11

    Recent CS grad, newly interested in this field. Your videos have been so helpful, thank you!

  • @seangray5897
    @seangray5897 3 роки тому +2

    You're helping me figure out what skills I need to develop before applying for grad school! Thank you for this channel and the helpful videos.

  • @juanma415
    @juanma415 4 роки тому +3

    Thanks for coming back! I watched your video from the beginning until the last seconds, and I loved it!
    I really like your passion for real science and the way you express your ideas.
    You're so lovely! Good luck in your job! Stay Healthy!

  • @vichobrega
    @vichobrega 4 роки тому +14

    Oh my, such valuable videos here. I just graduated with a bachelors in Biology and I am stuck on how to move forward. Trying to find a specialization or skill that I want to learn and apply moving forward to get a job, and I feel like bioinformatics can be extremely useful in todays biotechnology industry. Will definitely look into it based on what you said in this video. Thank you so much ur a geniussss

  • @jshan8348
    @jshan8348 4 роки тому +2

    So happy you are back, you are the reason I got into this field. 🎈

  • @makulmahato8663
    @makulmahato8663 2 роки тому +15

    You are one of those rare people who can explain and present bio soo beautifully. I watched one of your seminar recently and that was one of the best presentation i have seen. Thank you very much for that!

  • @evanhughes9576
    @evanhughes9576 4 роки тому +2

    Thanks a lot, Maria. This video provides a lot of direction. I immediately clicked on this video once I went to check in on my subscriptions.

  • @Squiderrant
    @Squiderrant Рік тому

    Really good practical advice. Thank you for sharing and providing links

  • @jeeyaihsan352
    @jeeyaihsan352 4 роки тому +1

    Good to see after you long break in good health.
    It was a good platform for student who want to do bioinformatics.
    Thanks

  • @suzannelong8090
    @suzannelong8090 3 роки тому

    This video was amazingly helpful with my research proposal for my final year project! Thank you

  • @DG-xg8vg
    @DG-xg8vg 4 роки тому +1

    Good to see you posting again!

  • @nathanadisu1855
    @nathanadisu1855 4 роки тому

    Nice to have you back !!! You are my mentor.

  • @fromzton
    @fromzton Рік тому

    Thank you very much for this valuable tips. I am starting my journey in bioinformatics and this information sets up a good basis to work from.

  • @ayoelegs
    @ayoelegs 4 роки тому +4

    Thanks Maria. I am from Africa and there seem to be a dearth of bioinformaticians on the continent. Your videos inspire and I am considering going into Bioinformatics after my PhD (Microbiology).

  • @farzanayasmin6173
    @farzanayasmin6173 3 роки тому +1

    Very helpful.....happy that you are back

  • @dobby224
    @dobby224 3 роки тому

    This is incredible helpful! Thank you for posting. You've made things easier for me.

  • @NoorBakeer
    @NoorBakeer 3 роки тому

    Thanks a million! You don’t know how much this was helpful for me. Please keep up the good work

  • @okposioemmanuel7223
    @okposioemmanuel7223 3 роки тому +2

    Thank you for this video. Really needed some guidance 🙏

  • @pagnininicollo5407
    @pagnininicollo5407 4 роки тому +1

    GREAT TO SEE YOU AGAIN! All the best wishes to you!

  • @seennchannel1127
    @seennchannel1127 3 роки тому

    I got an encouragement for learning bioinformatics from your channel. Please make more VDOs.

  • @dream-sage1017
    @dream-sage1017 4 роки тому +12

    Another useful and thoughtful video thanks a lot! And as a beginner, I definitely recommend Rosalind, problems in there really helpful to understand how python or in general programming languages work. But beware hours and hours long of mind-games are waiting for you ! :D

  • @sheldon12100
    @sheldon12100 4 роки тому +1

    Your videos are very helpful for non bioinformatician like me. Cheers! Please more videos.

  • @jeremyrodrigoguerreroalejo3466
    @jeremyrodrigoguerreroalejo3466 4 роки тому +8

    OMGG, I miss so much your videos. I am in my junior year of bioengineering in Peru and I super interested in bioinformatics. Your videos have helped me so much to start learning the basics of this wonderful set of tools. Thank you and I wish you the best in all your projects.

  • @sagek7949
    @sagek7949 3 роки тому +2

    This was superrrr helpful. Thank you so much!

  • @phebianodufuwa6106
    @phebianodufuwa6106 3 роки тому

    Thanks for this video. You've given me a headstart.

  • @preethik8864
    @preethik8864 3 роки тому

    You're amazing thank you for helping me start my Bioinformatics project 😊

  • @seyedrezamohebbi8744
    @seyedrezamohebbi8744 4 роки тому +1

    Great. You are back
    👍
    Hope you will find enough time to prepare such interesting educational videos. Take care

  • @caroleinwv
    @caroleinwv 11 місяців тому

    Thank you. Very down to earth and helpful.

  • @stes5429
    @stes5429 3 роки тому

    Really helpful, great you're back!

  • @paulmiranda1194
    @paulmiranda1194 4 роки тому +1

    Hi María, welcome back and thanks for ur videos :)

  • @zeynepa.2221
    @zeynepa.2221 3 роки тому +1

    You are so helpful to everyone :) thank u so much I hope you will achieve your goal :) greetings from Turkey

  • @ismailjjuuko1172
    @ismailjjuuko1172 9 місяців тому

    Thank you so very much for the time well invested. I am new to the field but with this great introduction, I'll make it.

    • @OMGenomics
      @OMGenomics  8 місяців тому

      Thank you! I just posted a newer video on this topic too, so check out my "Bioinformatics for Beginners" video today :)

  • @Alex-gw6pm
    @Alex-gw6pm Рік тому

    Thank you very much! it was so helpful video to know from where to begin. ☺🙏

  • @torlarsen2212
    @torlarsen2212 Рік тому

    This video was very helpful for me, thank you so much 🎉

  • @danielromero-alvarez5392
    @danielromero-alvarez5392 2 роки тому

    Thanks for the great recommendations, and for the nice ending!

  • @YudaDwitama97
    @YudaDwitama97 3 роки тому

    Thank you! your videos really helps me to start on Bioinformatic. Greeting from Indonesia :D

  • @FieldsDynamic
    @FieldsDynamic 4 роки тому +4

    Hi, is wonderful to see you again, please don´t disappear any more. Your courses are amazing. Best

    • @OMGenomics
      @OMGenomics  4 роки тому +2

      I will try my best to keep going this time! It definitely helps that you are all so encouraging and peer pressuring :)

    • @arunbioinformatician2231
      @arunbioinformatician2231 3 роки тому

      @@OMGenomics it really helped me to know more about bioinformatics
      I'm right now into PhD in bioinformatics
      I need Ur help in understanding it
      Can u help me pls

  • @MrErick1160
    @MrErick1160 3 місяці тому

    I’ve just got into bioinformatics PhD. Got my first meeting today. Feeling this is a new step in my life. Im so excited

  • @kamalkishorebaguant7042
    @kamalkishorebaguant7042 2 місяці тому

    Thanks a lot, you have been very clear. Bravo

  • @yashir9422
    @yashir9422 2 роки тому

    You are awesome. Please make more vidoes. I subscribed since you are very honest and clear. Thanks a lot. If you are my lecturer or a friend I will love it.

  • @juanmgut4234
    @juanmgut4234 4 роки тому

    Thanks, I would like see more contento like this! 😀

  • @nullbytes6282
    @nullbytes6282 3 роки тому +40

    Your videos have helped me so much, I’m currently an 18 year old apprentice working in a cell engineering R&D group. I started looking at bioinformatics and now I’m hooked, I’m learning python and hope to start applying some programs in my everyday lab work.

    • @austinkunch710
      @austinkunch710 2 роки тому +4

      Could you share what country your company is in/what company it is? Thank you

    • @ariat_yhimed8241
      @ariat_yhimed8241 9 днів тому

      hello, I would like to ask what have been up to and how are you doing today ? I am seriously in your shoes and I would like you to give me hope. I just heard of bio informatics and it is my first day looking into it. Please let me know .

    • @nullbytes6282
      @nullbytes6282 9 днів тому +1

      @@austinkunch710 Only just seen this - sorry! I’m in the UK (Cambridge) but the company is Swiss.

    • @nullbytes6282
      @nullbytes6282 9 днів тому

      @@ariat_yhimed8241 Hi! I’m doing very well, thanks. I am currently at the same company, and I was fortunate enough to convince them to sponsor me through an undergraduate degree in bioinformatics. So I currently work/study part time. Mainly working in the systems biology/functional genomic space. Switching from the wet-lab was the best decision I ever made (nothing wrong with it, my mind just works better behind a computer 😊).

    • @austinkunch710
      @austinkunch710 9 днів тому

      @@nullbytes6282 Cool! What's the company?

  • @sabarishb5496
    @sabarishb5496 3 роки тому

    Thanks a lot i am a UG student pursuing bioinformatics

  • @powerfulweapons1160
    @powerfulweapons1160 3 роки тому

    I'm a master student in Life Science Informatics in Germany, I haven't much clue about my course because it is also Bioinformatics but different name. Thank you soooo muchhh for your informative videos, your information make clear my vision and show me path in my educational carrier. Thank you again, Greetings from Germany by Indian Heart.

    • @SumitVerma-zt1vk
      @SumitVerma-zt1vk 2 роки тому +1

      @tushal
      From which subject and from which university you pursued bachelors program
      And
      How you get German university for Master's program

  • @futurepharma2818
    @futurepharma2818 2 роки тому

    👋 watching from Egypt, very helpful thanks

  • @dorrinsam
    @dorrinsam Рік тому

    Thank you for the roadmap. It really does provide many helpful tips, but please note that the command line is not a language. It's a user interface.

  • @sohinisaha4069
    @sohinisaha4069 10 місяців тому

    I am done with my masters in Human genetics and I am really confused as to whether I should be pursuing a phD in computational biology. This video was really helpful for me as I do think it gave me a place to start and see if bioinformatics is my thing

  • @jeread5193
    @jeread5193 2 роки тому

    Very encouraging and inspiring! subbed!

  • @surajpowar4915
    @surajpowar4915 3 роки тому +4

    Hello, Thanks a lot for your video. This was extremely helpful. I am applying to grad school for PhD in Computational Biology, I am mathematician myself. My potential projects is inclined towards modelling and simulation for genomics. Video had great ideas for beginner.
    P.S. Can you please make a video on how students from Maths, Computer Science and Physics can get into Biology research?

  • @910risha
    @910risha Рік тому

    Great Work Maria!!

  • @cuburtrivera1167
    @cuburtrivera1167 3 роки тому

    this is really helpful. thank you

  • @normansabin8322
    @normansabin8322 3 роки тому

    Video was great, thank you, keep it up.

  • @tiburon181
    @tiburon181 3 роки тому

    Excellent video !

  • @samiullah9154
    @samiullah9154 3 роки тому

    Welcome back. I have only you as a mentor in bioinformatics

  • @erikaendokokubun607
    @erikaendokokubun607 3 роки тому +3

    Thank you!! I'm a Master student about to start my thesis with bioinformatics and was feeling very lost, but this video really helped :)

  • @KoboraBC
    @KoboraBC 4 роки тому +8

    Thankyou so much I was enjoying the five tips a lot because I’m a sophomore in college but the ending really hit different for me as a young Afro-American I appreciate your amazing content please keep at it when you have the time #notificationsquad

  • @wilsonsevilla7490
    @wilsonsevilla7490 3 роки тому

    This is the video that I needed 🙏🙏🙏

  • @thatweakpowerlifter2515
    @thatweakpowerlifter2515 Рік тому

    Thank you so much.

  • @vitorpaiva5011
    @vitorpaiva5011 4 роки тому

    Thanks for back!

  • @betsi9183
    @betsi9183 3 роки тому

    My adviser speak to me about this career but I don’t know where start, I want to work with medical area and also biology I never thought in bioinformatics, thank for your channel

  • @victorrorisang479
    @victorrorisang479 Рік тому

    Thank you.

  • @Anatteby
    @Anatteby 4 роки тому +4

    Interesting how some things does not change - I did my Ph.D. 35 years ago and had the same experience reading papers in the beginning feeling frustrated because at the time almost all papers contradicted each other and it was hard to reproduce data

  • @unboxingcategory3353
    @unboxingcategory3353 2 роки тому

    you are so great, following you from now, give us some of your time

  • @1234567899921344
    @1234567899921344 4 роки тому +14

    I received some financial help to do a Phd in bioinformatics, I would have rejected the whole thing (coz bioinformatics seemed completely intractable at first) if it wasn't for your encouraging words.
    Much love and respect

    • @samiullah9154
      @samiullah9154 3 роки тому

      Assalam o alikum
      Mohammad Alfayyadh, I just completed my graduation in biochemistry n molecularbio. I really need someone who can give me some direction to advace in bioinformatics. Will you help me?
      sami.naazar1526@gmail.com

  • @marthenkenfag5731
    @marthenkenfag5731 3 роки тому +1

    Merci beaucoup pour l'orientation.

  • @awalk2remember3
    @awalk2remember3 3 роки тому

    I love the video , thanks for sharing it

  • @adamhall5332
    @adamhall5332 4 роки тому +4

    Yes! Your videos introduced me to the topic that I wasn't aware even existed. I am visually impaired, and was trying to go for wet lab science work, and it just doesn't work out. I think this would be a much better fit for me. I'd like to use bioinformatics and genomics to learn more about my visual impairment. There is very little known right now. Thinking about reaching out to universities in other countries who study it for some of their insights and maybe even data? Thoughts?

    • @OMGenomics
      @OMGenomics  4 роки тому +2

      That sounds like a great idea. Researching something that matters to you is fantastic. I’d love to read a blog or watch your videos about that journey :)

  • @xiolee7597
    @xiolee7597 3 роки тому +1

    Practically speaking, I would recommend learning linux/bash and python together to head start, because real projects need you to run various bioinformatics programs in the linux environment. The first stumble you would encounter is to set up your computer environment and installing those program can be a pain in the ass.

  • @sanaomar2182
    @sanaomar2182 2 роки тому

    amazing video

  • @Sarah-yo1hh
    @Sarah-yo1hh 2 роки тому

    Thank you 🙏🏼

  • @banyalaaabdulganiu1683
    @banyalaaabdulganiu1683 4 місяці тому

    very informative video , i most certainly got a handfull

  • @salvinatammaccaro2161
    @salvinatammaccaro2161 3 роки тому

    Hi! Very interesting channel! I am interested in learning bioinformatics :)
    My background is in biology! Thank you, you give very good and clear points to start with!

    • @OMGenomics
      @OMGenomics  3 роки тому

      Glad to hear it :) Good luck!

  • @mahmoudadelelkholy3130
    @mahmoudadelelkholy3130 2 роки тому

    thank you so much

  • @pralipthakumar9962
    @pralipthakumar9962 Рік тому

    Thank you 💖

  • @mistermirkorossi
    @mistermirkorossi Рік тому

    Very good video! Go on!

  • @leonardlarbi6809
    @leonardlarbi6809 2 роки тому

    It was very informative

  • @ceciltommy9283
    @ceciltommy9283 3 роки тому

    Thank you

  • @worldofinformation815
    @worldofinformation815 3 роки тому

    Thank you 🌹

  • @mohamedelmorsi6064
    @mohamedelmorsi6064 4 роки тому

    it was really good video
    thank you

  • @VerdadeiroDataBR
    @VerdadeiroDataBR 3 роки тому

    you are amazing! thanks

  • @BehindYouIsMe
    @BehindYouIsMe 3 роки тому

    This was super helpful, I'm so glad you made this video. This has helped a lot in informing my career decisions!

  • @oxygen2.781
    @oxygen2.781 Рік тому

    thank you so much 💜

  • @charlesedward4114
    @charlesedward4114 Рік тому

    Is interested video all abut bioinformatics I have enjoyed so much the mixed both field biology and information thanks a lot

  • @yv6eda
    @yv6eda 4 роки тому

    Thanks!

  • @raselsiddiqe8280
    @raselsiddiqe8280 2 роки тому +2

    Since this video is for beginners and as Maria is welcoming people to share, here's my first hand experience from learning programming to actually getting published.
    First, I went through an Introduction to Python course that got me familiar with loops, conditions, lists, arrays and dataframes. Now this was proving more than difficult because I had no practical way to apply what I was learning. So I went directly to the last step. Papers!
    Found some articles that were fairly easy for me to understand. From these I found some web based tools with simple use cases that generated data. After understanding what these tools were doing, I figured I should try to reproduce the papers using my newly earned python skill, mostly dataframes and csv module.
    What I did unique was I used my own sample space. So I didn't reproduce the experiments, I reproduced the experimental model on a different sample set.
    3 months later, I had a concrete dataset, and I had learned the basic statistical values from those papers to extrapolate new information from my samples. While this was on going I contacted one of my professors who had used Bioinformatics tools in his own work. He suggested i publish my findings.
    Fast forward another 3 months and I had my first publication. All from my own computer, without getting inside a lab or doing wet work.
    Not bragging or anything. Seemed like this was a good place to share my journey for others to learn from or at least get started.
    Ps. Currently working on a script that can eliminate most of the manual work I had to do so I can work with larger sample spaces. I also wanted to find an alternative to the web-based tools. There are python modules that work ofline on your computer so you won't have to get on the web.
    Cheers
    Link to my paper: www.ncbi.nlm.nih.gov/pmc/articles/PMC7835092/

    • @dinafitriana3144
      @dinafitriana3144 Рік тому

      Hello, may I know what is your previous background? So you need 6 months in total from learning programming to your first paper? Is it possible for someone from agricultural science go to bioinformatics? I did some molecular biology experiments for my master’s degree, it’s more into plant pathology though. I think I’m not good in wet lab 😅

    • @raselsiddiqe8280
      @raselsiddiqe8280 Рік тому +1

      @@dinafitriana3144 Yes! i did it in 6 months. I should mention that the 6 months were in the middle of the pandemic so I had more time in my day than usual. My background is Biochemistry and Molecular Biology. The paper was published as I was doing my Masters online.
      I don't see why you won't be able to take on bioinformatics from agriculture since you've focused on plant pathologies. There are tons of genomic and proteomic targets to analyze. So pick a protein or gene, see what tools you can use to analyze that protein or gene. Follow papers for guidelines (how to use the tools, what the results mean etc.).
      I was strictly working with full genome sequences that are readily available on the NCBI database. You can take up individual genes or proteins, do a BLAST to get started and then apply more tools as you go along.
      Don't think of programming as a skill you need to learn to become a Bioinformatician. Look at the problems that you can solve with computers. Then learn to solve them. Programming will let you do this solving on larger scale for more complex problems faster and more accurately.
      You can publish when you have some findings worth noting or if you identify a trend in the data that is unique/useful/unheard of. Good Luck. Have fun while you do it.

    • @kianaunlimited
      @kianaunlimited Рік тому +1

      Thanks it helped very much❤️

    • @naimathassan6844
      @naimathassan6844 10 місяців тому +1

      This is insightful

  • @nabildhifallah6964
    @nabildhifallah6964 2 роки тому

    yes it's impôrtant to be prepared with those useful steps

    • @nabildhifallah6964
      @nabildhifallah6964 Рік тому

      how to get the papers that helped me more for bioinformatics is there a video from yours that shows me their contents and thank you for you

  • @mbadaniel8852
    @mbadaniel8852 3 місяці тому

    I just came across your video while search for a way to get started in the bioinformatics field with no support to plug into, i must this is like a compass i really appreciate your effort. I would really appreciate it if you could help with links to learn this python in details, if possible free links to study the python programming and other areas as well once again thank you so much look forward to more videos

  • @kerolloseskander4035
    @kerolloseskander4035 3 роки тому

    Very nice video thank you Maria :)

  • @rgb5521
    @rgb5521 3 роки тому

    Yes! More videos! 🥰

  • @SHOAIBKHAN-fd2rd
    @SHOAIBKHAN-fd2rd Рік тому

    Thanks mam😊🙏❤️❤️

  • @1000hours
    @1000hours 4 роки тому +1

    I completed graduation, postgraduation in bioinformatics and am currently doing ph.D in bioinformatics .

  • @markappaduray4642
    @markappaduray4642 3 роки тому +4

    Loved the vid! I'm a cell biologist turned data scientist and now I want to move into bioinformatics. Are there any specific projects/problems that you'd recommend to start with when building up a bioinformatics portfolio? Thanks very much looking forward to more :)

  • @sogoljalali8358
    @sogoljalali8358 3 роки тому

    thanks a lot.

  • @aditi4677
    @aditi4677 2 роки тому

    hey! I loved the information you shared. I am a Statistics undergrad and I want to explore the bioinformatics field. I know python, SAS and SPSS and basics in other languages. I dont know any biology. How should I explore the field as a beginner?