Thiamine - Beri-beri and Wernicke- Korsakoff syndrome

Correction- excessive consumption of polished rice causes beriberi
For Medical and Dental students
NEET Preparation UG/ PG
Thiamine -
Active form TPP
Required for PDH, KG- DH, Transketolase
2 imp functions
1. Energy generation
2. Nerve impulse transmission
Deficiency causes
1. Dry Beri-beri
2. Wet Beri-beri
3. Infantile Beri-beri
and
4. Wernicke- Korsakoff syndrome
Reference
Harrison's principles of internal medicine
Vasudevan Biochemistry
Case oriented approach by Chhabra
MD Rafi
Satyanarayana etc.

[@shaikhshaukat7163]

Very nice, simple explanation. Recalled my college memory, in 1977 our professor was teaching us in same style and devotion
Progress of India is only due to this kind of devoted teachers and not by party leaders God bless you

[@obiwan922]

scammers spotted.

[@gamigpegu7611]

@@obiwan922 😂

[@dariankole4657]

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I was dumb forgot my login password. I appreciate any tricks you can offer me

[@dallaschandler2843]

@Darian Kole instablaster :)

[@dariankole4657]

@Dallas Chandler thanks for your reply. I found the site on google and I'm trying it out atm.
Takes a while so I will get back to you later with my results.

[@vridhimathur6804]

the simplicity with which you teach is the true essence of your lecture !

[@anganipoobal]

Thanks a lot for precise and informative lecture on each vitamins which is reducing the study time... i am referring it for my postgraduate selection exam. Thanks in heaps...

[@189asadurrehman2]

Sir thank u very much..u are my mentor in biochemistry ..i love to study on white classroom board ...and u make biochemistry easier for me..thanks a lot...❤❤❤

[@096harikrishnank5]

Great work sir, it is very helpful to understand the concepts.

[@AjeetKumar-wj9bk]

Thank u sir. And u uplaod some cases regarding specific topics that is great work. Thank u so much sir.👏

[@user-rp8hv1sw4y]

Sir literally it reduce my time to learn vitamins thanks so much

[@farehalira5429]

Very nice lecture Sir....I wish I could see it earlier❤❤❤

[@drsangharsh]

What an amazing person.. ❤️❤️

[@veeranarayanan5963]

Excellent. I wish I should have watched this video two years ago.

[@JYAN2852]

Thank you so much Dr Rajesh! You just saved my mother's life. Now I know what to do to help her because none of her doctors know what's wrong

[@faizanquraishi4126]

Ummm.... I still don't think you should try to self diagnose if the doctors themselves didn't get it....

[@JYAN2852]

@@faizanquraishi4126 I cured my mother's illnesses. Doctors were a waste of time. They poked and proded her, loaded her up on drugs for years. Their diagnosis was that there was nothing wrong with her

[@faizanquraishi4126]

@@JYAN2852 good for you. If you don't mind me asking what did she have?

[@JYAN2852]

@@faizanquraishi4126 Classic beriberi caused by white rice consumption. She just needed supplements. Reversed her diabetes too. Got her off all 10 meds. Her doctors are all perplexed and called it a miracle. They know nothing of nutritional deficiencies

[@faizanquraishi4126]

@@JYAN2852 good to know she is well now.

[@chrism3188]

My father (lifelong excessive beer drinker), stopped eating and slipped into a severely declining state over the pandemic resulting in him being unconscious on the ground for 2 days having lived off beer for a few weeks. He was diagnosed with WKS and spent 54 days in hospital (was stable and could've been released 2 weeks earlier but he was still recovering and his final discharge assessment would determine if he kept his medical power of attorney, so we kept him there hoping to get him over the bar).
Luckily his organs recovered quickly in hospital but his walking (ataxia) and his memory (new short to long term memory) were severely compromised. We were told he would likely need full time care for rest of his life and he may never walk. I worked with him daily starting on day 15 in hospital through discharge for 60 days both physically and mentally and slow recovery was noticed, i got him to shuffle walk and remember things for 1 hr, then 2 then a day, but progress started to noticeably taper and was almost stagnant at around day 120.
All the research I did basically said there is basically no treatment (given neuron brain damage) other than 100% no alcohol and vitamin B.
But then I started looking into TBI and stroke recovery since there are some parallels and found some recent stem cell trial results that looked very hopeful. I tried to contact several research doctors but no response and there weren't any new trials soon or that i wanted to risk him being in the 50% placebo group so I looked for clinics internationally and found a few. after looking up reviews and distances we ended up choosing Bioexcelerator in Colombia. The clinic didn't have any experience treating his condition and was hesitant because of the rate of progression from continued alcoholism, but I advocated hard and they accepted him as a patient.
6 months after his hospitalization we were in Colombia and he got 110 million stem cells injected via IV(Not as needed) and 40 million stem cells injected intrathecally into his spinal cavity fluid to migrate to the brain (this was the main hopeful treatment).
48 hrs later he was noticeably sharper and clearer eyed, 72 hrs later he could remember details from earlier in the day or a movie he was watching much better, 2 weeks later he could still remember his trip to Colombia and what connecting flights he was on and where we stayed on the route from Colombia to Canada, etc. 3 weeks later he drove himself to his dental appointment, settled the bill and drove back home all on his own with his face frozen! and now he recites summaries of articles he read in the paper 1-3 days before.. It's been like a miracle.
I felt like I needed to share my experience in case it helps even one other person, we still have a long road ahead and we pray his recovery continues at the current pace, we are now on week 4 after treatment.
As positive as my father's response has been, I can't say it would be the same in all cases (i don't want to give false hope, but I do want to give hope and credit where it's due) we also don't know yet how far the treatment will help him get back to his former baseline, as you may know, WKS is considered as a spectrum from acute /temporary(Wernicke) to more chronic/permanent (korsakoff), FYI in my dad's case the doctors indicated based on his clinical diagnosis and MRIs he was likely mid spectrum with some definite permanent damages but hopeful prognosis on some recovery over many mths/yrs.

[@artlovelily8144]

Hope that ur father recovers soon

[@amaan7028]

Thanks for sharing this kinda information…I just started med school and am starting to realise the value of the information taught to us by the books, teachers and the patients

[@Sasuke-lp7mp]

​@@amaan7028prepared for 1st proff?🤧

[@nabeenashrestha9874]

I learned from u more than books😄

[@deekshachauhan3906]

Sir you are the only biochem teacher each and every student of medical College want to study from with their own desire.....you are great.....hats off you!!! Sir you are awesome 🙂🙂

[@xoxo5200]

Does he follow satya book of biochem

[@sivaranjinin1470]

@@xoxo5200 raffi book

[@rishitavats788]

Amazing leacture....sir.❤️❤️👍👍👍 but aap inka structure bhi provide krte toh bhot shi rheta ⚡

[@VasuDev-yx8rq]

I am bds 1st year student your video is very easy explain this topic thanks ☺️ sir

[@atmaaimforchange3700]

Which college bro

[@user-uc9nm3xx1b]

Thank you so much sir...for full series of vitamins......

[@Curious31]

Thank you very much sir.. Too much helpful for me

[@charlesbooc3191]

Thanks doc n God bless us all

[@janmejayamohapatra6543]

Sir I think there should be polished rice besides of unpolished rice, nice explain sir thank you

[@Rajesh_Jambhulkar]

Yes, correction is there

[@janmejayamohapatra6543]

Thank you sir for your quick response.❤️❤️

[@kashifarmani3468]

Sir which source do you follow

[@snehavimal5772]

Awesome lecture sir

[@artlovelily8144]

Our professor brought 400 slides of vitamin b and c and read out some 200 slides and chapter was completed in 6 days . I didn't understood what was taught.
Ur vedio just made me complete it in 1 day .

[@jennyvarshavski3138]

Are u exaggerating ?? Or he really brought that many 😮

[@drsunilmeher8046]

Thank u sir ,this is really helpful to me....❤️

[@doctorofmedicine1113]

Ist viwer from kashmir... exclusive o7m video

[@reddy459]

Really indebted to u sir...

[@Rajesh_Jambhulkar]

Thanks

[@elliemunro3165]

Very interesting and easy to follow..thank you !

[@aergulcelestia419]

Thank u so much sir...❣️❣️❣️

[@ghrumbijjar7283]

Sir g y r video clear all the thing

[@aliyabaloch7088]

Thank you so much sir 👍

[@aryakumar963]

Great work sir 😍😍

[@salmaabdo9128]

Thank you sir 🌺

[@VeerSingh-fs6dw]

I wont be surprised that most of us do not have optimal intake of thiamine through nutrition.

[@springtime9828]

Thank you so much .

[@yogiyogesh815]

Thanks .....Dr.Rajesh

[@yourpharmabuddy9177]

Thanks a lot sir 🙏🏻

[@medicoUsamaNaseer99]

Informative 👍🏻

[@SasaPast]

Thank you

[@someshkolhe5435]

Thank you so much🙏

[@santhoshpatilmedmania2600]

Impressive teaching sir

[@ajayprasad4075]

Awesome ❤️

[@misty_jeera]

Thank you!

[@thanujaasalla1414]

Thank you sir!!

[@tejaswinich9421]

sir upload a video on pantothenic acid also

[@priyalimohapatra2390]

Awesome sir🥰

[@sradhakv2359]

Thank you sir

[@ramyagubba6779]

Simply superb 👌
Thank you sir !!

[@anjalijangra9011]

Thnku sir 🙏

[@sunipa318]

Awesome 👍

[@drparth1234g]

Sir I think u should do 2-3 case dicussion by yourself

[@shashipandey5768]

Thanks sir ...very conceptual vedio

[@rashtrapaldhupe3547]

Thank u sir

[@ishitamondal2496]

Sir in the causes of beri beri u say that unpolished rice intake causes deficiency in B1 ...sir I think it will be excessive polished rice intake...

[@Rajesh_Jambhulkar]

Yes

[@Rajesh_Jambhulkar]

Thanks u

[@ishitamondal2496]

You're most welcome sir....Ur videos are very much helpful

[@rajshekar7852]

Thank you. even I got confused a lot at that point.

[@Rowan_Chris61]

Awesome sir♥♥

[@drlife151]

Does tea and coffee causes thiamine deficiency aur it is present in tea and coffee

[@mirunalinik5179]

Sir please upload pantothenic acid also

[@samyakchoure1350]

Tooo amazing sir... ✨✨🤩🤩😇😇🙇🏻🙇🏻 Thank you for such amazing explaination.. ✨✨

[@chandakashyap3144]

Great sir

[@kbbbkk7275]

thank you Sir,
Is thiamine sulfur containing vitamin?

[@Rajesh_Jambhulkar]

Yes

[@sundareshachalyaanantharam6770]

Sir what are the antagonist of thiamine

[@ulfatlone6989]

Sir my daughter is 9 months 15 days she was diagonises by thaimen defcency,by mri

[@dr.bharatramanagrawal1429]

Sir, may it possible that there would be a combination of dry and wet berry berry in a single patient.

[@Rajesh_Jambhulkar]

Yes

[@jyotsanapareta3483]

Sir after doing ur notes and lectures is it enough for writing mbbs 1sr year final or do we need more?

[@Drravikumar03]

Ask seniors and look into pyqs. You will get an idea.

[@skjamiluddin9901]

thanks sir

[@muhammadjunaidali4007]

Awesome

[@NazmulHasan-oj5ow]

Nice lecture

[@arifullahullah]

Thanks sir but plzz explain the thinks slowly
Not every student got your method

[@sumannagpal6615]

Wonderful

[@barshadey4195]

If unpolished rice is the staple food and it is also a source of thiamine then why is the man suffering from thiamine deficiency?

[@Rajesh_Jambhulkar]

Correction is there
Correction- excessive consumption of polished rice causes beriberi

[@barshadey4195]

@@Rajesh_Jambhulkar thank you sir

[@rishabhagrahari7611]

Best❤️❤️❤️

[@archieducation]

Sir , there is difference bw thymine nd thiamine pronunciation

[@girishdakliya8563]

Sir, can we have pdf or written notes of ur lectures???

[@Unique_boy_12321]

I have pdf

[@kavyamaniraj7157]

Really ur lectures are awesome sir.. But is this enough for presenting in exams or should we add more

[@Rajesh_Jambhulkar]

Enough

[@shifanmankad2133]

@@Rajesh_Jambhulkar thank you so much sir,such an amazing videos, you help us so much and clear our concepts easily

[@aakashyadav9288]

hello sir
i am a 2nd year medical student and today i watched your video it was a good experience.
But sir i have a request to you if you can then please try to use hinglish in your videos, as it will become more easier to be understood.
I hope you are getting my point , so please think over it.
Yours truthfully.

[@jeswanth0759]

so you are telling him to confine to only hindi students
he is teaching to medical students
not to only hindi medical students

[@unnatipatidar9837]

Sir cause of dry beri beri includes chronic alcoholism too??? Or it is just cause of wernickes koraskoff??

[@Rajesh_Jambhulkar]

Yes, it causes deficiency manifestations of Beri beri

[@kajolagrawal682]

Sir pls can u make videos on fat soluble vitamins also

[@Rajesh_Jambhulkar]

Yes, sure

[@Hayatkhan-by6bd]

Sir plzzz help meee mera exam h ek question ka answer chahye plxxx sirrrr rpky krdy 🙏🙏 answer abi chahye

[@prabhatgupta-jz7iu]

Sir dietician syllabus hindi medium ki video youtube par Kar dijye sir please

[@premsai6612]

CVS means???

[@nilaselvakumar]

Sir notes kedaikkuma vitamins ku

[@Mbbsfiles]

Sir I have a doubt
At source slide you said that unpolished rice contain thiamine
But near the causes of beri beri you said that it occur by unpolished rice as staple(daily) diet
As beri beri causes due to less thiamine how can it caused by unpolished rice ?????
Please explain🙏🙏

[@Rajesh_Jambhulkar]

Yes u r right
Polishing removes 80% of thiamine.
When consumed as staple diet causes beriberi

[@Mbbsfiles]

​@@Rajesh_JambhulkarThanks sir❤

[@ojasvithakur1305]

Sir plz elaborate some difficult words like edema and acute fulfimnant CVS

[@christo8394]

Go find out by yourself
Just do some work 😂

[@bhagirathchandrasarkar2990]

Discussion is very excellent .please discuss on Alpha lipioc Acid for human consumption.Waiting for you.

[@munna3daudiobase377]

Wonderful time

[@christo8394]

For whom 😂

[@toastedoven5418]

Look like vijaysethupathy😂❤

[@Rajesh_Jambhulkar]

😊😀❤❤

[@NazmulHasan-oj5ow]

From Bangladesh

[@t.jeyanthi.5116]

Sir pls upload regulation of blood sugar

[@Rajesh_Jambhulkar]

Available

[@aryanmehta4351]

If I just follow your video and not read the text will it be fine ?

[@Shahzadi2801]

Yeah he has explained everything

[@subankarsarkar6830]

Sir u mentioned unpolished rice as a source of vit b1 . Deficiency of which causes beri beri but u also said eating unpolished rice causes the deficiency I am getting confused! Please reply

[@Rajesh_Jambhulkar]

Correction- Unpolished rice is good for health, polishing removes 80% thiamine

[@snehagondal3239]

Sir can hyperemesis gravidarum be caused in infants ?

[@noknack9187]

In Keto acidosis it happens

[@mbbsgalaxy9127]

8:55 Sir the cause should be excessive consumption of polished rice right?

[@delta__404]

Thanks for spotting a mistake

[@bilawalsohrani1135]

😍😍

[@sandipjadhav8577]

Nice sir❤️

[@healthyfast7974]

Vitamin B1 (Thiamine) | Sources, Functions, Causes, Symptoms and Deficiency
ua-cam.com/video/X6Y8jydD15c/v-deo.html

[@niyatiaghera4871]

Case study me 'polished rice' aana chahiye na, 'unpolishes' ki jagah?

[@Rajesh_Jambhulkar]

Yes

[@ragnarok9197]

🔥🔥❤️

[@patelmayank205]

9:02 is correct? if yes i am unable to understand

[@Rajesh_Jambhulkar]

It's wrong
Correction is mentioned in discussion

[@yousfrasool3730]

♥️♥️♥️💖

[@shahbaz9231]

Sir, isn't Infentile beriberi actually wet beriberi?

[@Rajesh_Jambhulkar]

Yes

[@manisharathore3929]

1)- Dry beri beri
2)- TPP (thiamine Pyro phosphate

[@abithambbs5718]

🔥🔥🔥🔥

[@healthyfast7974]

Vitamin B1 (Thiamine) | Sources, Functions, Causes, Symptoms and Deficiency
ua-cam.com/video/X6Y8jydD15c/v-deo.html

[@Narendrakumar-kn6lb]

1 deficiency of vitamin b1
2 TPP

[@healthyfast7974]

Vitamin B1 (Thiamine) | Sources, Functions, Causes, Symptoms and Deficiency
ua-cam.com/video/X6Y8jydD15c/v-deo.html