Nobel for mRNA Vaccines: Penn Varsity Claims Credit After Sacking Laureate|Vantage with Palki Sharma
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- Опубліковано 2 жов 2023
- Nobel for mRNA Vaccines: Penn University Claims Credit After Sacking Laureate | Vantage with Palki Sharma
Katalin Karikó, once demoted by the University of Pennsylvania for her mRNA research, has won the Nobel Prize alongside Drew Weissman for their groundbreaking work on COVID-19 vaccines. Despite facing career-long struggles and a forced retirement, Karikó's contributions are now celebrated, although UPenn omits her past demotion in their statements. Palki Sharma brings you the full story.
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Medicine | Nobel Prize | Katalin Karikó | Drew Weissman | mRNA Vaccines | University of Pennsylvania | UPenn | Firstpost | World News | Vantage | Palki Sharma
#nobelprize #medicine #katalinkariko #upenn #firstpost #vantageonfirstpost #palkisharma #worldnews
Vantage is a ground-breaking news, opinions, and current affairs show from Firstpost. Catering to a global audience, Vantage covers the biggest news stories from a 360-degree perspective, giving viewers a chance to assess the impact of world events through a uniquely Indian lens.
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She’s the best example for “work in silence and let your success make the noise.”
or stealing other people works too.
Not a winning strategy as someday never comes.
@@luzdeld Your accusing Dr. Kariko of 'stealing' is disgusting! She has worked with mRNA research already in Hungary. That was a few decades ago.
@@luzdeldthere is no pride in that
@@Fido-vm9ziWhy should she not have pride in her work?
As an American, this news is very well done and is highly accurate with regard to how our academic system works. Bravo for doing the research that so many news outlets do not do, at least in our country.
Are you one of the Ivy League communists who run those schools?
Penn is the ultimate organization for driving incredible doctors out of the University. I have 3 awesome doctors who driven out from Penn by mistreatment, and their stories are nauseating.
Universities and academic institutions always do that. This is very normal for them. Its a game of power, jealousy, hatred, greed. Flattery wins. Shoe lickers stick to the positions. Just you buy a new car here in a private Engg. institution and they throw you out. They cant tolerate such things. They give education to people ! Are they really worthy? Not at all. If you buy a house in the same city where you work, they throw you out of job and force you to work in different city. Academia is gone into the wrong hands and Govts have become hopeless and useless.
Is there any "quality control" on the evaluations they come up with ?
Mmmm. Pattern of behavior...
I can see a class action lawsuit from those affected.
@@manuelmoraleda9684 First of all there should be the information released in a public domain regarding complete procedures and evaluation steps and the quality control steps. Make the procedures in public. In research there is a subject for course work called research methodology. They should replace it by 'how to successfully complete the procedures' in the very begining of the research work. If a person passes this course, even University can't stop the person. But, will the universities do that? They won't. It's all about the procedures the universities deliberately hide from people..
Dr. Kariko has a nobel. She can write her ticket to almost any university in the world.
Incredible congratulations to Dr. Kariko who was demoted by Penn for not winning enough grants but persevered through their short sightedness. She is a true inspiration.
I too congratulate both Karikó Katalin and Krausz Ferenc, but our education system is catastrophically bad and our nobel prize winners aren't the result of it. Basically every great hungarian person ever has emmigrated from here.
Covid-conspiracies are rampant, the media and every institution is state controlled just like during the soviet era, literacy rates are low, and we are among the last countries by every statistic in the EU.
@@airtale8725 absolutely right
Whether or not you get tenure depends on how much funding your lab gets and the reputation it aquires while you are an assistant professor. In her case however she was an adjunct professor, and those positions (for research anyway) are part time and funded by grant money you bring in. The later is particularly important since you are expected to do independent significant research if on tenure track, and you need grants to fund that. If you can't get enough grants to support your lab you won't get tenure no matter what, it is as simple as that. Essentially you have to arrange your own salary as well if you are an adjunct prof, it does not come from university funds, so normally you are paid by another professor, a company or the government. Those positions are sort of halfway between a post doc an an assistant professor position (which salary the university does pay for) and there is an understanding that eventually you are going to move on. I would guess she was unable to do that adequately and consequently had to move on, it kind of works that way and happens at every university routinely. Adjunct professors are not permanent and it is assumed you have some more permanent job somewhere else.
BS
@commercialbreak8290 What is BS? That is what an adjunct professor is. You get four types of professors. Adjucts, who are basically part time and get largely paid from external sources, not the university itself unless they teach some courses, which they may be paid for. Assistant professors, which are the the first stage of tenure track. They don't have tenure though, meaning the university can dismiss them. The university pays them a small salary, but they have a period in which they are expected to establish themselves and get their labs funded through grants. If they do that they will get tenure, if they don't they get pushed out. Then you get associate professors, the next step on tenure track. They have tenure but are essentially junior professors. The university pays them, but salaries are lower. After that you get full professors, they are the senior positions in tenure track and get paid full salaries. All of the senior leadership in the university will be drawn from the last group, such as department heads, deans, named chairs, etc.
Kariko was an adjunct professor, meaning she was being paid primarily by external sources and those sorts of positions are usually pretty precarious since the department does not have funds to pay salary, other than for any teaching you might do.
The problem with this video is that they don't appear to understand the differences between the four types of professors. The issues faced by Kariko are the same issues every adjunct faces, they are NOT secure positions unless you work for a company or the government but have your lab in the University.
Thank you for sharing this story. It's really disgraceful the way that Penn has treated Ms. Karikó. An apology and promotion is long overdue.
"Even with the right tools, there's always the risk of failure", Palki Sharma, Firstpost, 2023.
That statement cannot be overstated and should form the mental anchor when dealing with scientists, especially on research.
Kariko, a true icon of integrity and intelligence. A model for all women! UPenn should take this loss as a signal to change their attitude. I know other people who went to Penn and were faced with this snobby elitism... which BY THE WAY offers significantly less monetary compensation than any other places "because we are an Ivy League." Nobody needs this kind of attitude.
Awwwwwkward.
I went to a university that had a professor win a Nobel Prize while I was there. As far as I can tell, his job for the next year was being trotted out to every possible event as the university prize pony. "Give us money, we have a Nobel winner." UPenn may have some... difficulty in this case.
Im kinda surprised, this isnt an isolated case, nor an isolated uni, the united states forces so many people to be adjuncts and work multiple jobs that its now just kinda commonplace, really glad that people might look into it now that it happened to a Nobel Prize winner
Terrific story. Well written and well spoken. Thank you.
This is the challenge faced by most Biomedical researchers in almost all the Universities in UK and USA. It's a tough job with terrible pay. It's better to drive a Uber than be a postdoc or research staff nowadays. R &D is long term but they give 2 years contract or one year renewable. How can there be innovation under such conditions.
Things need to change, otherwise when another pandemic comes, there will be no safety-net
Look up Douglas C. Prasher, the Cindarella of molecular biology. Osamu Shimomura, Roger Y. Tsien and Martin Chalfie won the 2008 Nobel prize for their development of the fluorescent jellyfish protein, which is used to identify any given protein in a biological sample, on all those dramatic color photos on the covers of Science, Nature and Cell. Prasher discovered the gene for green fluorescent protein, which he shared with Chalfie and Tsien, but he didn't get his grant renewed, didn't get tenure, and wound up driving a van for a Toyota dealer in Huntsville, Alabama for $10 an hour. When Chalfie and Tsien found out what happened to Prasher, they publicly gave him credit for his contribution, and paid for his trip to Sweden as their guest at the Nobel prize award ceremony. Prasher finally wound up working in a tech company in Alabama, and then for Tsien's lab.
Things have certainly chainged in the last 50 years. My college professors told me that in the 1950s and early 1960s, if you got a PhD, you were guaranteed a tenure-track job. By the late 1960s, it was musical chairs. In my self-serving opinion, I think we should spend as much money on biomedical research as defense. (Or more. COVID-19 killed more Americans than all foreign wars.)
both researchers stole the limelight from robert malone.
Quote from Wikipedia: "As of October 2023, Karikó is a professor at University of Szeged in Hungary."
Perseverance wins !! Ended with a nice and inspiring statement 👍🏽
just imagine life of Gregor Johann Mendel.
More important takeaway, don't care who laughs at your work and effort. Objectively assess the feasibility (including the criticisms) of your work and if you think it is feasible go on with it. Also, don't get swept away by the accolades, these were the same people who were laughing at you some years back.
Why did she rejoin the same institution after having such a horrific previous experience?
This type of story is not untypical for Nobel-prize winners. Stanley Prusiner, for example, was ridiculed in the scientific community for years about his ideas on the causes of mad cow disease, but in the end he had the last laugh and a Nobel prize. Shinya Yamanaka was ridiculed among his colleagues for his ideas on induced pluripotent stem cells, but in the end won the Nobel prize for it. Shuji Nakamura was ridiculed in his company while developing techniques to produce blue LEDs, but in the end won the Nobel prize. Need I go on? It underscores what an extraordinary achievements these scientists have accomplished to qualify for the highest scientific reward.
Great piece of journalism
I don't usually follow your content, but thank you for exposing how grubby and greedy the university business has become. I believe yours is an Indian channel, awareness of this needs to be spread among Indian youngsters because many of them end up studying in UK/USA/Canada/Australia/NZ universities that only want their money.
It is not a question of who gets credit. It is a matter of who will finally take the blame.
Did either of the Nobel Laureates give credit in their acceptance speech to Dr Robert Malone who, as accepted by the US Patent Office, got there before them.
Failure is orphan but success has many fathers... who is this Rob Malone? No records in scientific literature.
@@melaomelao8689Dr. Robert malone is a physician and biochemist who is known to be the father of the mRNA vaccines
@@melaomelao8689 Robert Wallace Malone is an American physician and biochemist. His early work focused on mRNA technology, pharmaceuticals, and drug repurposing research. During the COVID-19 pandemic, Malone promoted misinformation about the safety and efficacy of COVID-19 vaccines. (Wikipedia)
No, he didn't. Malone spread misinformation.
@@RebeccaTurner-ny1xx What misinformation did he spread? Wikipedia is not a credible source lmfao.
Wao, how clever of them to take all the credit now, shame on Penn University
Palki, Your research on your news subject matter is impeccable !!!!
You too are an excellent journalist.
Continue like this …. Noble Price or not.
Pulitzer
no other news media put up so much efforts like you to go deep in any subjects
No one talks about the Furan cleavage or that a Moderna patented DNA strand has been identified in the COVID virus. Dr. John Campbell has a more informed view.
Dr. Kariko deserves the award. My daughter works as a Researcher Associate in the Biotech Germany.
This is not the first example of its kind. There are many. One example I have heard by word of mouth, but found no documentation. A geologist researching earthquakes, came to a finding that an earthquake was likely in a certain area. Businesses did not like the idea and asked the employer to terminate him. According to the terms of employment, he had to be given a notice of some period. Before the period ended, an earthquake took place, and the notice was withdrawn.
Where´s Dr Malone?
"They told me that they'd had a meeting and concluded I was not of faculty quality."
Well that statement might be true but perhaps not in the way they intended it.
You expressed surprise in the print interview about why non Indians follow you. It’s due to lack of credible journalism in the west and also in India. You are a rarity. Your looks also help, but main thing is your integrity. And if you slip up, then we will call you out.
this is worth a movie i would pay to see. what a story.
This Lady has researched the vaccine for over 10 years. That puts a stop to those people who were saying that the vaccine was thrown together in minutes. Congratulations, however, I would not have gone back to Penn for all the money in the world.
The 'TRUTH WILL OUT' - as they say ....
Last two lines are most imp. for life..🎉❤
Great video.
They should fire the bosses who had zero credibility!
US university is racist. Kariko is not Anglo Saxon. She is Hungarian. Penn now wants to bask in Her reflected glory - after practically sacking her in 1990's by threatening a demotion if she does not quit on her own.
You do have a point about the Anglo-Saxon phenomenon. Not too long ago they ruled most of the planet, then plummeted to the normal level of humanity. Since then it is 'sour grapes'. How dare a non-Saxon entity show ingenuity? (lol)
@@OldPannonian should have been using a protease inhibitor, all along. Like Ivermectin, another Nobel Prize winner.
They called it horse de-wormer...
Explain the other guy, Weissman ?
She does not need promotion, the nobel prize was the biggest slap on Penn. She should refuse anything from them
Palki Sharma! This is where you went after WION??? Subscribed!!
Queens College in NYC now only hires adjuncts..
Shame on Penn for falsely claiming credit for behaving like total yutzes in the face of these revelations.
I give personal thanks to Kariko. I am effectively unable to receive regular vaccines due to treatments for an autoimmune system disorder. (I produce too much of a secondary immune system.). The only treatment available destroys any vaccination and leaves me vulnerable to contracting anything I am vaccinated against, for months.
mRNA is safe.
Gratulalok, minden jot,orulok, hogy gyo”zo”tt! Dr. Kariko!
Ja, mondjuk neki is emigrálnia kellett, hogy sikeres legyen. Magyarország egy ugar ahol csak parazita gombák és futónövények pusztítják magukat és egymást.
God is watching all of us. God bless you despite what they did to you. I hope God gives you back your discovery credit and recognition
I doubt that God theory.
Most biologists and other natural scientists are atheists.
@@user-lb8bg6kj9m Sorry to interject here. Most human beings on Earth have and still do believe in 'that God theory'.
@@OldPannonianquantity doesn’t mean quality.
@@australia-ukraine You are too materialistic. I have nothing in common with your world view of the Universe.
I hoped they would be prosecuted instead.
Why?
You all should write for 48 Hours Mysteries. Definitely left me with more questions than I started with.
My God! Shame on this Penn… what idiots were able to drive out such a scientist? Are they still there? Infuriating!
Thank you great video
it is good that U Pennsylvania step forward to disclose accountability so that people who were injured can ask them to testify too.
Her success is a mark of shame on their judgement and their institution
God bless the scientist for not giving up.
for what? People are dying all over the world and you want to glorify this murderous inventor?
@@elvinmarvel7643 Nobel invented gunpowder, Moniz got Nobel Prize in Physiology or Medicine for lobotomy, Obama got the Nobel Peace Prize. KARIKO and WEISSMAN lucked out and profited handsomely with the pandemic. So did Bill Gates who purchased Biontech shares in 2019 Summer.
@@elvinmarvel7643how is she “murderous”??
@@RojaJanemanshe’s the creator of the notorious MRNA clot shot that’s killed hundreds of thousands of adults and children around the world WAKE UP!!!
@@elvinmarvel7643 The covid vaccines have saved an immensely bigger chunk of humanity from death, than those who 'are dying'.
Get your statistics right!
Thanks for this interesting video!
Pen state should express a statement of apology... . they should demote the people who actually were the culprit.. that's the best way to feel the pain@pen.. non sense attitude
Not Penn State. University of Pennsylvania, Penn Medicine. These two lucked out with the pandemic.
So did Bill Gates who purchased Biontech shares in 2019 Summer.
A woman still needs to fight for her place in this era.
🎯
Nothing to do about being a women. If you misuse victimization for non related issues then you harm your cause.
Everyone has to fifht for their place. Everyone.
@@tahmeedmazumder6877 - Women and minorities especially.
She is a Hungarian woman working for a German company.
and Dr. Robert Malone ... this is bs ...
He is worth his salt too ..many of his then collegaues died by now, who really knows who did what there back then.
Now he is insanely jealous of these two, Kariko first of all.
@@ytcomms3945He has been against the use of mRNA vaccines in humans after the trials killed the subject.
Starting in mid-2021, Malone received criticism for propagating COVID-19 misinformation and conspiracy theories, including making "dangerous" and misleading claims about the toxicity of spike proteins generated by some COVID-19 vaccines;[4][32][6][33] using interviews on mass media to popularize medication with ivermectin;[34] and tweeting a study by others questioning vaccine safety that was later retracted. (Wikipedia)
@@RebeccaTurner-ny1xx you must get paid to troll around and spread disinformation.
excellent report
Shocking beyond words 😡
She lucked out with the pandemic. Her research colleague, Dr. Drew Weissman worked with Tony Fauci as his postdoctoral student, before he moved to UPenn in 1997.
She was also complaining a lot about how she was treated in her native country, Hungary, in the 2021 April New York Times article.
She got excellent education and was treated well but Hungary is a small country and they could not come up with funding for such a nascent field. By now she toned down her complaints about Hungary as they rewarded her with various prestigious prizes and honorary professorships.
Hungarian here: this country is a shithole and she was right to complain. The education system is rotting, funds for it and research are dropping, corruption is rampant, universities got taken under direct control by members of the one-party-state who also censor and block researches, academist and scientist payments are abysmally low, the population has serious literacy issues, libraries too are underfunded, book producers were also taken control of by fidesz party-members as were all of the media and our whole economy. This place had not contributed to the success of either Karikó or Krausz.
Before the pandemic mRNA vaccine development was largely focused on treating cancer. Although that hasn’t come to full fruition yet, it is possible and even likely that just the impact on cancer treatment will be worth the Nobel Prize.
@@jeffreysnyder290I have a feeling it's a fraud.
What an uninformed comment. Read her book. I'm reminded of the saying that it's best to keep your mouth shut and be deemed a fool than open it and remove all doubts.
IVY league colleges are not what they appear to be, believe me.
Good one!
If he is going to take the credit let him take the blame for the fact that it isn't really a saving drug.
How research works in India?
Parents, I've an Idea, I want to pursue research in,
Parents: Research is lame, Engineering and Medicine is great, you must study that
Student after struggling hard to get out of imposed degree looses interest in research,
Also parents, why aren't Indians doing any research and getting Nobel prize?
Do u know the % of funds that GOI allocates for research during annual budget? 😂
You don't know anything 😂
OK so what about prize in Literature and peace?
Just having an idea doesn't mean you can do research. You have to study first then you get a real idea and then think about research.
Sue them. How dare they love u enough to tell u d facts on d ground??
Palki at 1:40 nobel peace price. Your focus & analysis on war & peace is so deep that it is witnessed here. Yes noble price for medicine!
It might be Noble for some but it is named NOBEL after the name of the inventor of the gunpowder.
Moniz received it for lobotomy. Obama was awarded the Nobel peace prize.
It is Nobel Prize.
@metarus208 Oops! Auto dictionary. Didnt realize. Thanks!
Good report.
So wot, Academic Bureaucracy has ever been backstabbing credit thieves.
That's par for the course when dealing with schools out to either make a name for themselves or make their prestigious selves bigger.
Nobel Prize has lost all meaning ... No credit to Dr Robert Malone who actually invented mRNA years ago.
Not Penn University 1:30 ... University of Pennsylvsnia, Penn Medicine. You got it right the first time.
They lucked out with the pandemic. So did Bill Gates who purchased Biontech shares in 2019 Summer.
Yeah, I’m sure it was just luck.
R&D is required, not many realize the potential when the iron is yet to be considered warm. The risk & reward possibility is higher, that keeps many away.
If you fund 100 people one may get outcome. Luck may also play an important role alongwith hardwork.
@@infoinadvance681 - Luck favors the prepared.
The two's story is worthy of a movie.
@atabac - With Meryl Streep!
this is like when your manger claims your hard work is because of him ...
The American tax payers should get partial credit for providing the funding, without their knowledge, as well as not receiving ANY of the revenue from pharma corps.
Good, we know who to take to Nuremberg.
Dr. Kariko's story is inspirational. However, a scientist research & publications produced while affiliated to a US university belongs to the institution - so U. Penn claiming credit is not appalling. U. Penn's derogatory, unprofessional treatment of Professor Kariko is appalling. But, why Prof. Kariko returned to U. Penn - as an adjunct - when BioNTech embraced her work - is beyond appalling, even narcissistic. Her story is not unique in medicine and science, unfortunately.
I wonder why she returned as an adjunct if they pushed her out and said she was not of faculty quality, and considering she had a well paying job, Senior VPs at biotech probably pays more than University salary, as they get fat bonuses and also equity in the company. I am guessing she made good money with her shares from BioNTech. I am curious why she returned to U Penn.
Perseverance wins Amen
Highly deserved win
नोबेल तो दें अवश्य जिस को भी वो देना चाहें. ज्योर्ज सोरोस को क्यूं ना दिया जाय? क्यूं ना दिया जाय फैसर के मालीकों को? कोविड-१९ के निर्माताओं को.
You are kidding, aren't you?
@@OldPannonian और क्या जी, आप को क्या लग्ता है वो हमारे मोदीजी को देंगे? नोबेल जैसे मैली पुरस्कार मोदीजी के लिए अपमान जनक होती है जी.
Organisation, corporate and institutes become political place with deeply motivated and shrewdest running the show of nepotism and favouritism. They don’t like meritocracy and go by their self interest. Such places are bound to fail in long run
True. They do these types of horrible things routinely
As that tweet said.. it shouldn't take a Nobel prize to bring out such humiliations of hard-working talented geniuses!
what a corruption, this is an international horror of jabs.
Penn University should be ashamed. The University should express its regrets, emit a public apology, and award her a retroactive tenure. She is a very unique person that has been battered by the highfaluting academic bureaucracy. These presumptuous authorities should recognize their error, instead of attempting to validate their position, as any good scientist would do.
Thank you gor highlighting the university
The more I hear about Penn State the more I dislike the institution.
Why did she return to Penn? Is she mad?
For some reason, she no longer works with Biontech since last Autumn.
She was complaining a lot about her original homeland, Hungary in the 2021 April New York Times article.
By now she toned it down as she is getting all sorts of prizes and honorary professorships from there too.
Well said. Shame on UPenn
Dr Robert Malone was actually person who invented MRNA. Please do the research.
I did. He wasn't.
If that happened here in Canada, the university would be paying the ex employee a huge severance package worth at least six figures.
IIRC, due to her demotion, at some point her employee (postdoc probably) was getting paid more than she was.
The truth about academia is that it concentrates on publications and citations. Nobody wants to have too original a research area, because it is hard to be published and too few people to cite your paper.
Thank you for the information. I did not know that Dr Karikó had to endure this toxic treatment. It is like the AppleTV+ series, "Lessons in Chemistry" played out in real life. All the best for her future.
Glad I saw this. I think maybe it's time for me to leave Pennsylvania.
A Nobel prize for something that causes myocarditis, cardiac arrests, an explosion in aggressive cancers, and DOESN'T prevent COVID infection or spread? Why?
Those side effects you mentioned were rare. The vaccine saved millions of lives around the world, including mine.
Here in 🇳🇿, at most two confirmed cases of myocarditis from the vaccine, from several million shots administered.
They keep a careful watch on side-effects, for precisely this reason.
You can bet that senior administration at Penn have given themselves huge pay raises at every opportunity.
That’s so typical of our world. The man gets tenure and the woman gets fired and laughed at. Go her for speaking up and not letting them get away with being schmucks. RBG said something like women belong in all places that decisions are being made. It should not be that we are the exception.
Palki, you always dig out the truth 👏
Construction of mRNA vaccines requires the insertion of the encoded antigen in a DNA template from where the mRNA is transcribed in vitro. 3:03 [NCBI]
mRNA basically uses our own body and biological processes to potentially treat diseases and prevent infections.
mRNA vaccines are an attractive and powerful immunotherapeutic platform against cancer because of their high potency, specificity, versatility, rapid and large-scale development capability, low-cost manufacturing potential, and safety. 3:33 [NCBI]
mRNA is made from a DNA template during the process of transcription.
mRNA cancer vaccines are a powerful and versatile form of immunotherapy. mRNA cancer vaccines are able to encode and express TAA, TSA, and their associated cytokines, and these vaccines can induce both humoral and cellular immunity. 4:48 [Frontiers]
Does the host yell?
I’d recommend watching the film “Picture a Scientist”. Women have it disproportionately rough in science. I doubt the administrators at Penn will have any change of heart, but this is an opportunity to be shaken out of their complacency.
Also the fictional series on AppleTV+ - "Lessons in Chemistry" about a woman in the same situation.