Methotrexate for Rheumatoid Arthritis and Psoriatic Arthritis
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- Опубліковано 6 лип 2024
- Methotrexate is one of the most common medications used for patients with inflammatory arthritis like rheumatoid arthritis or psoriatic arthritis.
#methotrexate #rheumatoidarthritis #psoriaticarthritis
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In this video, I will answer the most common questions related to methotrexate therapy:
0:00 Intro
2:17 --What is Methotrexate?
2:44 --What is the effect of Methotrexate in Arthritis Patients?
3:51 --Is Methotrexate a pill or an injectable medication?
4:46 --Is Methotrexate a “chemo” drug?
5:17 ---Can Methotrexate be combined with other medications such as biologics?
6:03 ---What are the most common side effects?
7:51 ----How to monitor if methotrexate is safe for your body?
8:22 ----Can methotrexate affect your organs?
10:05 ----Why do you need to take folic acid with methotrexate?
10:58 ---Can you drink while taking methotrexate?
11:32 ---Can you get more infections while taking methotrexate?
12:21 ----Can you get vaccinated while taking methotrexate?
12:52 ----Is Methotrexate safe for pregnancy?
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👩🏻⚕️ About me:
Dr Diana Girnita is a double board certified physician in rheumatology and internal medicine. She completed a PhD in immunology, a postdoctoral fellowship at Harvard University, immunology fellowship at University of Pittsburgh and rheumatology fellowship at University of Cincinnati. Dr. Girnita graduated from the Nutrition Science course from Stanford University and a Mindfulness course from The University of Massachusetts; She is the founder & CEO of Rheumatologist OnCall, a practice focused on broadening access to rheumatology and offering patients an integrative medicine approach.
Dr. Girnita teaches patients about autoimmune disease, arthritis and also helps them customized their treatment plans. Dr. Girnita is passionate about rheumatoid arthritis. The treatment plan is personalized to the patients needs and incorporates the proper nutrition, exercise and management of stress. After all,
"You have a disease, but YOU are not the disease"
* The information in this video is not intended nor implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a medical consultation. Any comments and/or recommendations made in the comment section by anyone other than Rheumatologist OnCall does not reflect our opinion or recommendation.*
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I’m on methotrexate and it has lessened the severity of my pain. It was extremely severe.
The best ever explanation
Really Thank You!!! From Ethiopia 🇪🇹🇪🇹🇪🇹
Newly diagnosed and finding Your videos very helpful, and explained clearly. Very much appreciated.
Thank you 🙏🏻 for watching!
Thank you for all this wonderful information! ❤
Please subscribe and share with others to spread the knowledge! Thank you 🙏🏻
Wow. This informative video answers so many questions I had about taking methotrexate. Thank you Dr. Girnita!
Thank you so much for watching!!!
Thank you so much. I learned new and valuable knowledge about methotrexate.
I am taking methotrexate twice a week with folic acid.
I was diagnosed with RA at 24 and now 19 years later I have been taking methotrexate for at least 12 years with no serious issues (@ 8-10 pills). As long as I take folic acid consistently I do not have hair shedding or breakage.
Thank you for supporting my UA-cam channel!
Why do you need to take folic acid as well
Ty 🙏💕 just started this today. Been nervous about the hair
I'm 41 years old and I just dignosed feel very lonely and sad and scary with this arthritis r...dr want take this medicine im scare this medicine is kill me for inside my body please let me know how u all guys feel and is damage this medicine for inside?ur stymphos and ho many months or years ur been take it?thank you and god bless you hope very very soon find a cure❤❤❤❤❤
@@AventurasLiz I’m 39. Been having fibromyalgia going on for a year and a half, and the joint pain for 2.5 years. I was really scared to start it too. Talked with a cousin of mine that was on methotrexate for 5 years and she loved it, for the pros. I can’t speak for longevity of it, but I can say I feel better right now, than I have in 3 years. Ever. First day after felt nauseous and like when you have the flu. Second day a bit better but super fatigued. Last two days have been the best I’ve had in years, so worth it to me as of right now. Just make sure to take folic acid with it, drink tons of water, follow the advice of your doctor if you decide to. Prayers for you to decide what is best for you in this. 💕
Thank you so soo much for this bit of info
thank you for watching my videos!
Very very valuable video for us. I am a lady and also rheumatoid arthritis patient and taking Methotrexate since last August. I am suffering from rheumatoid arthritis from last year. Thanks a lot doctor for your information and concerning about us.
Thank you 🙏🏻
Thank you doctor I take methotrexate I feel little better.u have explained very nicely.bless
Thank you !
Excellent information!
❤
You are so welcome!
Since watching your brilliant videos I have learnt a lot, the information you share is invaluable thank you
Happy to hear that!
Thank you so much dr. God bless you.
You are most welcome
Thank you, very simple, ease to follow important basic information…
I'm glad you found the video helpful!
How do you feel about Moringa natural plant for pain and inflamation
Thank you for clear explanation 😍😍
You are welcome 😊Thank you for watching my video, dont forget to subscribe to my channel for other videos!
Briliant, thank you :) you have explained all so clear, much better that my visited 3 diffrent rheumatologist when I ask about this meditation
Glad it was helpful!
Doctor. Are there any medicines to completely control rheumatoid arthritis?
I am so happy that I found your channel…. Thank you very much
Thank you
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Is there a relationship between Methotrexate and constipation?
I was given methotrexate and solphadine tablets together and it made my bone marrow stop working
I was on Methotrexate injections for around a year, and to make a long story short I will let you know what it did to me. It triggered lung cancer, Sjogrens, lichen sclerosis and shingles all within months of each other. There were so many things happening to me at the same time, the doctors couldn't keep up with it all. And yes I had a lung X-Ray done before going on it and my lungs were good. The cancer was the size of a grape and thank goodness I had an excellent lung surgeon who removed it. My life is a Living hell now and I blame the methotrexate.
Thank you for sharing! sorry to hear that! I hope you are ok now! thank you for watching my videos
I’m so sorry and I’m so thankful for reading your story . In 2 weeks I have to decide what med to take! Honestly, I think to go all natural and take things as it comes 😔
@@light-yi2meI'm also thinking about going natural route. But my POTS, Sjogrens and other conditions are so disabling that sometimes I get tempted to get immunosuppressants.
@@renu653 maybe do it for a short while to get things under control then consult a naturopath doctor to help with your diet . I know that what I consume has direct effect on my health. Dark shade veggies, dairy and sugar are my triggers.
@@light-yi2me yes may be I'll try for a short course. But I have chronic infection in maxilla , so dentists don't want to allow immunosuppressants.
I'll try avoiding dairy and gluten. Due to mast cell activation, already I'm avoiding night shades and other high histamine foods. Thanks
My husband use predsidone and celecoxib
Very nice and informative vlog 🌹💖
Glad you liked it
I am a retired RN who has had RA x 20+ years. I was surprised the video didn't mention the side effect of anorexia. I took injectable methotrexate starting about a decade ago, when I started I lost my appetite, I finally understood how it really felt to not have an appetite. I worked for some time on an inpatient oncology unit, never knew what to really tell patients except what we learned in school. I always describe the first 5 weeks as this, I would say to my wife around 5pm: " I haven't eaten anything today, and I don't care". I lost about a pound a day, lost over 30 pounds before I acclimated to the drug.
Another side comment, this is how Methotrexate helped me bond with a little girl who wasn't even 4 yet and receiving chemo for ALL, (acute lymphocytic leukemia). She was traveling into Boston (45 miles away) twice a week, for labs then administration of the chemo drug if labs were OK. I told the local MD I would take her own as a chemo patient in her home, I visited on Thursday in the AM, drew labs off her porta cath (a central line directly into the aorta) and then sent them to the local hospital lab. The results would go to Boston Children's Hospital, then they would contact me if I could administer her chemo drug on Friday morning. The first visit I drew labs, the second visit I gave her chemo. The mom looked at me and said "in Boston, they wear an apron, a face shield and the special long gloves, you only wore gloves, why?" I told her she was receiving Methotrexate on Fridays, and on Saturdays I took the same drug, just a slightly higher dose. So, even if I got a little on me, no risk. I saw the girl thru her two years of treatment, she was finally cancer free. When the family had a 10 year celebration of her cancer free status, I (and my wife) was the only medical person invited to the party. She is now a college graduate, and grew up to be a smart beautiful young woman. It was a very small part of my nursing career, but those type of successes make a career seem worth the deaths you watch.
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Can we chat with you for your advice.
@@julietaferreira2244 Certainly....
Thank you.
You're welcome!Thank you so much for the kind words! Highly appreciated!
I have RA for many years and take Methotrexate, 2.5mg, 7 pills, one day a week. I take Folic Acid 1mg on the 6 days of the week when I don’t take Methotrexate per my doctor recommendation. I have not had and serious side effects other than some kind of weird mouth sore inside my mouth. I also been dealing with split ends (due to use of flat iron). Do you have any more tips and so forth?
from last 5 years I am on leflunomide and rituxibhax infusion and I am very happy and has worked with me
I have RA, diagnosed in 2007. I have been taken methotrexate for 15 years. I now have developed neutropenia, and have been taken off Methotrexate as this apparently is not uncommon, but I was never told that there was any chance of developing such a terrible condition. Please be sure to advise people of the side effects, so they may make an truly informed decision
That is what I am doing!
Thank you for watching!
👏✊
I was on mexaltrexate when I was on Remicade and it seemed like it was helping me. I started to notice that I was having trouble breathing and that was helping more frequently so I ended up having to go to emergency room and was hospitalized. I was not able to breathe for some time and I was on constant oxygen while hospitalization. The doctor told me that I had to be taken off the medication because of my breathing problems. I was on a oxygen supply for about a year. I have been off the medication since but and haven’t felt like myself since before my diagnosis.
Thank you for watching my video and supporting my educational efforts!
I know I keep saying this, but your channel has provided a wealth of education for me and my RA. I finally feel like I have more knowledge now about my RA & meditation therapy from your channel more than any RA Dr. that has been treating my illness. Still no relief and I’ve been prescribed Methotrexate, and prednisone. Prednisone works occasionally, but it make my body blow up. I only will take it if I’m in really bad shape. Methotrexate doesn’t work at all for me. Is there any other options for me? Thank you for a very informative & crucial videos.
Thank you for your support. Your words mean so much for me
I've been on methotrexate for seven years and I've realised It may be the cause of blood in my urine after I had kidney and bladder tests they couldn't find anything wrong I am going to ask my consultant to try something else
I was on Methotrexate until ny liver enzymes were elevated too much, then I was on Leflunomide until that elevated my liver enzymes. The side effects were skin issues and hair loss and dizziness. I never got good relief, until I was willing to try the biologics. I went through 4 and the last was Xeljanz and it's been giving a more quality of life, since 2/2015. There's been a few bumps, but overall, I'm happier.😊
Thank you for sharing your journey! It's inspiring to hear how you found relief after trying different medications.
Thanks for this video i have h psoriasis taking methotrexate but i hv nausea while taking .
Sorry to hear that
I have RA. I am on methotrexate pills. My dosage is 7 2.5mg per week. Now I have a real problem. I am having a hard time getting my prescription filled. Since the Supreme Court decided to do what they under oath said they wouldn’t and reverse Roe vs Wade, the very red MAGA states have put very strict laws in place about abortion pills. Methotrexate was tested many years ago for the purpose described. It must be taken along with another drug to work as well as needing to be (I believe) 150mg or 60 pills. I found out the companies have stopped production of them. I’m not sure what my future treatment will be yet.
I had this years ago for cancer treatment and am now on it for psoratic arthritis .im also on leflumonide. Hate that i have to be on it for the rest of my life. I was told not to take folic acid the same day as the methotrexate though. I take one the day after and one 2 days after that. Only 2 a week, should i take more?.
I take 2mg a day or I get mouth sores. Your doc should monitor your levels.
I tolerated methotrexate very well at low doses but it stopped working for me so I had to up my dose to 10 pills/week. Once I did that, I started having severe side effects. 1) My hair fell out in handfuls 2) It put me into menopause and I started having 20-26 severe hot flashes/day. I thought I was having a heart attack with every hot flash as my heart beat so fast and hard. My husband and kids could see it pulsating. It was a nightmare. I stopped the methotrexate and went on to birth control to get my periods to return and stop the severe hot flashes. It took at least 6-8 weeks of birth control to stop the hot flashes.
Hi, was there an alternative that works for you?
@@vishwamintramnarine1974 I am now on Humira but am having side effects with Humira too…possible drug induced Lupus (will be tested on Monday). I’m have pretty bad rashes on my face and my skin is super, super dry and hot
@@Nicolef888 thanks for sharing
@@Nicolef888How did your lupus test go? Is drug induced Lupus reversible?
@@AVERYGOODFRIEND95 Thankfully, I do not have drug induced Lupus, just an allergic reaction to the Humira. It has become less as I have continued to use Humira, I take 2-3 antihistamines daily.
Yes , drug induced Lupus does resolve after stopping a drug
can you please recommend dietary requirementsandsupplements so keep joints swell less thanks once again
See my supplements videos
ua-cam.com/video/Dee9cxlXmmc/v-deo.html
Please inform me food for breakfat, lunch and dinner. Thank you
join my course!Thank you so much for watching my channel!
What if you already have the symptoms you listed from Lupus? Does the methotrexate make the symptoms worse?
not usually!
Hi Dr. I just started methotrexate and folix acid 3 days ago and now i started to have frequent urination. Should i concerns
Thank you for watching my channel, share the videos to spread my educational content!
I have rheumatoid and osteoarthritis plus lupus and tri-geminal neuralgia. I'm about to see a new rheumatologist and I'm preparing my questions. But I'd like to go armed with background information and respect your work. I'm currently on Mycophenolate.
You can do it!
@@rheumatologistoncall Thank you.
same 🙏🏾🙏🏾🙏🏾
My grandmother was put on this drug , she died of lung cancer,
@@bigdebs1886which med is better do u think
I was on metadata for RA. My immune system went in the toilet. Never would I take that medication again
iam pharmacist and i have rhumatoid arthritis he give me 7 and i take 5 its help alot on methotrexate i double cortisone dose and second day i take brufen and after that one tablet voltarin 50 mg once daily or once every two day …it help alot dont take full methotrexate so you dont get side effect
befor i take voltarin 50 mg twice aday and one prednisone 5 mg every day and flare never subside but with methotrexate i start reduce voltarine dose
Does it weaken my immune system?
Feaver and other decease caught rapidly?
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I do not have Rhuematoid I am told.....lol but when blood work was done, I was taking Voltaren twice a day for pain due to osteoarthritis. My mother , sister , my child all have RA. Now my ankle is always stolen and painful. The bones in my feet are painful. Could the medication I take for osteoarthritis mask the diagnosis of the R.A.?
Hi, I also have osteoarthritis and now psoriatic arthritis without skin involvement. I've had a lot of trouble with my right foot swelling like crazy. I would ask your doctor to do an MRI of your foot and ankle and see what's going on. That's what sealed the deal on my diagnosis. The only thing I'm taking right now is meloxicam about 3 days a week. I have never taken methotrexate although it has been discussed many times. I had so many setbacks with three surgeries in a short period of time at the end of 2021 through April 2022. I had proximal row carpectomy of my right wrist because of a completely spontaneous necrosis of my scaphoid, my gallbladder went really bad, and then I had foot surgery on my right foot for huge ganglion cysts that grew out of nowhere on the top of my foot. In the process of all of this, with MRIs, other problems were found which pointed to the PSA. Good luck, I hope you can get some answers soon! Edited to add, we had to halt starting methotrexate because in the process of my gallbladder going bad, it messed up my kidneys, liver and pancreas for a while. They're more sensitive since then. That's why I can only take meloxicam 3 days a week.
I was on methotrexate and Hydrocloriquin for approximately 6-8 months for RA and Fibromyalgia. Over the time I was on these meds I slowly developed numerous side effects. Gaving balance issues. Last one losing the feeling in my legs and tingling in my feet. I have degeneration in ALL of my cervical discs. I'm totally confused as my RA doctor sent me to a neurologist for my cervical degeneration and he said he was conservative and wanted to start me with PT. Then I return a few weeks ago and my RA doctor tells me there's nothing that can be done for my cervical degeneration. Yet the neurologist didn't tell me that. Anyway, I don't recommended Methotrexate to anyone. I didnt have positive results with it.
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ua-cam.com/video/QeIS4vFKx9E/v-deo.htmlsi=loDBMiqWeCB2-EOb Dr Eduardo Beltran LGS protocol and Vit D therapy
doc...i need to take that medicine...how? can i buy over the counter??? i have been taking diclofenac 50mg,,then i stop it...then now im taken a celecixib...but the pain still in my knee and in may hand ang joint elin my elbow..what should i do? pls..i need your advice doc? im now in my stage of menoposal..ived just in counter my athritis this dec..firstweek..pls.notice my comment thankyou
Please contact a rheumatologist and get their professional opinion. You cannot take this medicine over the counter.
Big difference compared to what you are taking will take care of the pain but different drug neighborhood
Past 3 years l am on folitrax ( methotrexate) first 7.5mg then 10 and now 15 mg. But my doctor prescribed methotrexate to be taken on every Saturday after dinner and 5mg folic acid on every Sunday. So I take folic acid only once a week. Is that ok? As l read here that folic acid should be taken daily.
folic acid should be taken daily
According to the rheumatologist that examines me, he said that my reactive arthritis is turning out to either psoriatic arthritis or ankylosing spondylitis. The treatment he prescribed was naproxen on the first of December, then on the twenty-second he advised that I stop taking naproxen and he switched me to Medrol 16mg. The past Wednesday he also decided that I should be receiving methotrexate injections for 3 months, so far. During the first month, I will also continue taking Medrol 16mg, however not the whole pill, he has given exact guide on it (3/4 of the pill for a week then half for a week then 1/4). Am I doomed to be taking methotrexate for the rest of my life? I've read that reactive arthritis is gone in 90% of the patients taking methotrexate for 6months. Is this true or shall I accept my fate? Thank you.
Thank you for watching!
This must be more than reactive arthritis
@@rheumatologistoncall I guess I am doomed.
Dose of methatraxate used by patients any detail please, I am also a patient of pshoreitic arthritis. Rpl
10-20 mg weekly
@@rheumatologistoncall thank's, for responding, would you like to share your Whatsup number ma'ma. I AM FROM PAKISTAN
Mam my yefe paganrt ma khiyaga to Kiya hoga
Thank you for sharing your thoughts!
What is considered a low dose vs high dose of methotrexate?
10 mg is considered low
25 mg is considered. high
I took methotrexate for RA for 7mths. Huge amounts of hair loss. It made me very very sick.
Sorry to hear that!thank you for watching!
Same here and peeling of skin around my nails as if my skin had been burned leaving it raw. It then got hard and scabbed over. I couldn't touch it cause it would break open and bleed not letting it heal for weeks. That's only one of the things this med caused when I took it.
My test reports have indicated RA and Rheumatologist has prescribed Methotrexate 2.5mg twice a day once a week along with Peptazole. Going by all the side effects mentioned I am reluctant to take it. isn't there any other with milder side effets or none at all which could be taken. Mine is jusut the onset not severe
Plaquenil or hydroxychloroquine?
Minocycline?
Sulfasalazine?
Discuss all these options with your doctor
Thanks very much dr. Appreciate yr quick response. The drug alternatives you hv prescribed will not give any adverse side effects is it?
My partner on abitrexate/methotraxate and we want to have a child,unfortunately she experience severe pains if she forgets to take her weekly dosage....meaning stopping for preganancy maybe
She can be on cimzia that will allow her pregnancy. Talk to your doctor about cimzia
@@rheumatologistoncall thanks i will check with our rhemathologist....because we havent been to one..she was diagnosed by physician...i feel like we should talk to rhemathologist...so i will brinf this to her attention and get her views....
am still not sure if in SA we have that...but she will advise
Is hydroxychlorouine s for rheumatoid arthritis .
yes, a video will come
Yes
I lost my appetite is that normal?
yes, sometimes!
Thanks for watching my videos!
My doctor give me this methrotrexate 2.5mg , Folic Acid, prednisolone 5mg, rabeprazone sodium 20mg celecoxib 200 but I didn't continue i just use 4monthd because of too much laboratory and very expensive so I use home remedy like eating flax seed, pumpkin seeds but still I'm suffering
It sounds like you've been through a lot with your treatment. Have you considered discussing alternative options with your doctor?
Will methotrexate make an infection with COVID worse? Are live vaccines safe with methotrexate?
No live vaccine on Methotrexate
Methotrexate and COVID infection- not enough data to say will make it worse
@@rheumatologistoncall ty
Maam how is your rheumatoid arthritis now?
Thank you for supporting my UA-cam channel!
What are natural alternatives to Methotrexate?
thank you for watching!
Did u find ans for alternatives to metho
Did u find ans for alternatives to metho
Thank you
Welcome!
My sister was put on this drug for psoriaic arthritis. She developed rare side effects and no GP (UK) or hospital doctor noticed even though she was repeatedly taken into hospital. She had no checks before being given the drug and no proper check ups afterwards. It was prescribed by a dermatologist not rheumatology. My sister eventually died after emergency surgery for blocked blood vessels in her bowel. This tells you the state of British medicine. I could never take this.
I am truly sorry about your loss.
@Dr. Diana Girnita - Rheumatologist OnCall thank you. I do think if the proper checks and blood work had been done before she was given the drug, and the consultant had made themselves more knowledgeable, my sister would still be alive.
I'm using this medicine since December 2022
So sorry to hear that, however things are the same if not worse in Canada!
First of all, I am very sorry for the tragic loss of your sister.
But take heart as all is not bad in the UK, I went to Rheumatology after my excellent Endochrinologist/Diabetes consultant referred me, I had a full consultation with the Consultant, immediately followed by a chest x-ray and blood tests, then full training by the nursing sister on Methotrexate, how and when to take it, side effects, an information pack with advice helpline and prescriptions to collect on the day for Methotrexate tablets and Folic acid. The Methotrexate was clearly labelled as ONCE Weekly dose only, with a diary to record dosage dates with the dosages prescribed each week. I also got four blood test requisition forms to book every two weeks after starting then monthly then three monthly.
All UK NHS, so experiences it would appear vary greatly, but that said, I appreciate is no consolation, since nothing can bring back your beloved sister for which I am truly saddened.
Doc pwede tagalogin mo para maintindihan naman sa iba na hindi marunong mag engles
acetyl choline
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Great i will like to learn m0re
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Ki
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Methotrexate made me so sick that I had to stop it after 6 weeks.
So do I
Pill or injection?
@@arcadia5607 pills
Same. I took the pills and then I tried the injections. They both made me so sick I thought I was going to die. I was lethargic, developed fevers, severely fatigued, and I became dehydrated from the constant vomiting. I couldn't concentrate, my vision was blurry, and my blood pressure kept fluctuating.
@@bosslady7611it makes my husband feel sick for days. Did you find a medication that helped without feeling so sick?
In other words, "cure" is worse than the disease. I'd rather live in severe pain than risk death.
I understand that everyone has their own perspective on what they value most. It can be a difficult decision to make when faced with the choice between pain and the unknown.
Exactly. I prefer pain. I'm used to living with it. Unknown scares me...also, healthcare for profit scares me. @@rheumatologistoncall
Did u have srthritis r?
No thanks.
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methotrexet is terrible drug
What. Ridiculous comment
Why do you say that?
its bad for organs increase infections too
Thank you.
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