I did an infusion in 2018. It cured my lifelong anxiety and depression. I am autistic. I didn't know it then though. A single treatment was all it took for me. Cured me. No other drug or therapy did that. Ketamine heals.
I'm fascinated at your results. I am also autistic, and just started infusion therapy for my treatment resistant depression, PTSD, and chronic pain. I couldn't believe how much better I felt the first week! I don't feel like the 30mg lozenges do anything, but they tell me I'm not supposed too feel anything, and it's just to keep a baseline level in my system. I was really surprised about the IV experience. I thought I might feel more of an altered state, or hallucinations, or something, and expected to have thoughts or feelings to go over with my therapist. However, the other medications they gave suppress that for some reason, which makes me feel a little cheated on the therapeutic potential. One thing I noticed is that everyone else said they slept through their infusions. I was reading, watching TV, and doing puzzles. Made me wonder if my dose was low, or if it was just my neurodivergence.
I really appreciate your videos. I have been getting ketamine IV and IM's over the past year and a half, for C-PTSD, depression and anxiety. It has been like a miracle for me. I feel like myself again. I am so grateful for this treatment and hope it will be FDA approved for depression soon. People deserve to know about this drug.
Wow, thank you for sharing this. I’m on the waitlist to start getting ketamine infusions and haven’t been sure what it would be like. This makes me very hopeful!
Hi Linda, I had the IV yesterday (just one day is given here in the Netherlands) and yesterday my back pain stopped completely, but then today I feel it again. In your case how did the pain stop? Immediately? 😪
@@brendaeberwein8338 Oh me too! I’m up by the border in Bellingham Wa. On disability ( $1347/mo) and they do have 2 new Ketamine treatment centers here in town. But, soon as I mentioned that word to my obviously completely unaware Dr, her tone was that of a shrill freaked sort, like I was looking to get horse trancs, for real. Did not help me. I looked into it, and the cost is too high for my pockets and they don’t accept Medicare up front, yet. I’m hoping though in future they will more readily. It’s established, we are all getting great vibes here anyway. 😊❣️, that goes a long way for me living with chronic pain and anxiety, some depression and bad insomnia. I watch him and he just makes me feel better ❤️🩹🌻 Pray you all feel better too!!
I was given ketamine years ago, and felt it was amazing I felt better for a long time. But here, in my state you will not get pain treatment. Question; Is Ketamine addictive? I have Chronic pain, Lupus, absolutely diagnosed neurologic problems throughout my body and so I am looking into going to Colorado to try psychedelics hoping I can get some help. This is tragic that pain is not treated as it wears one out. Thank you Doctor for your kind heart and for educating the masses... We appreciate you!
I did get ketamine infusions. The first time I felt like I would imagine it would feel like if I was dying. It was horrible. Horrid anxiety and nausea. My blood pressure went up to 199/100. The Dr said not a problem that it will come down. I needed help to get to my car. ( my husband drove me) but horrible experience!! However, the next couple days it was a miracle! I literally felt lighter and even my neighbors noticed. I have severe depression over the loss of my daughter. I went 3 more times at lower dose, then back up to first dose and I never got back to those couple of days I did well. The anxiety and nausea was too much and I couldn't afford to keep going.
Thank you very much for the information. I've been to a Ketamine infusion clinic for Occipital and Trigeminal Neuralgia. My anesthesiologist is the most compassionate and caring Dr I've ever seen. I've had initial rounds of IV Ketamine which took all the pain away for 14 days. Unfortunately, my insurance companies refuse to pay for it, so I pay out of pocket for emergencies. He does also prescribe me oral Ketamine every month which helps me to not have to take addicting and stronger meds nearly as often. Finding compassionate and well knowledgeable Drs who use Ketamine is a key. Thank you for all you do.
Thank you for sharing your experience. I was recently diagnosed with Trigeminal Neuralgia, and just had my first infusion yesterday through my doctor's office. It was a low dose IV over 4 hours. I had pain through the whole session, which was frustrating, and am not feeling any difference yet. I realize I may need more infusions for it to benefit, but I'm curious about your experience with dosage and length of time for IV? I'm struggling not to get really depressed as well, as this has pretty much limited my life to focusing day and night on some level of pain management, so it feels like higher doses to address that would be helpful as well.
@jenbraswell8396 - I too have ON & TN and have for 22 years. I went 10 years without a diagnosis. Finally started having pulse radio frequency ablations of the occipital nerve that made it manageable, but it's hard to find a doctor to do them and insurance doesn't cover them. I just finished a round of 6 Ketamine infusions (125 to 250 mg going up 25 each treatment) and they are working well so far, but it's only been 4 days since the last one. Have you tried anything else that has worked for you? I've found that nothing touches the pain and I've tried just about everything. Narcotic meds only help for the short term, but have their own issues.
Both my family doc and my pain doc have recommended Ketamine for my depression and chronic pain, both caused by my MS. I cannot afford it though, so I am unable to see if it will work. The cost and unavailability just add to my depression.
There are so many instances proving that it helps people with such a variety of things. I really hope that it is covered by insurance soon. The out of pocket cost is insane!! I'd like to try it for several of my issues, but I can't afford it either. I also can't get any other kind of help. So I'm just stuck suffering 🙃 Something needs to change soon. I hope we can get access to it reasonably in the future 🙏
Suffered and suffering anxiety and depression. Would love to have infusions...unfortunately it is unaffordable for most people. But thank you for you sharing this information. ❤️
Thank you so much for explaining! This video showed me you really listened to the results of your recent survey as to what people really want to learn about. Awesome!
Thank you for this well-timed video! My pain management team recommended I try ketamine infusions, and I did not know much about it. I appreciate you sharing your knowledge.
When I had gallbladder surgery, I actually needed so much and many different narcotics. I have to have such large doses of ketamine, fentanyl and versed because I literally detoxify those drugs so fast so it makes everything risky! I have amnesia so I don’t remember how the ketamine was administered. If my surgery was only like a 5 minute scope test I can probably get away with using propofol but anything that takes longer than 5 minutes, I will need something stronger than propofol. I didn’t want to risk waking up during surgery again while having my sternum cut open so I went without sleep and marijuana and I had the anesthesiologist give me ketamine.
Having been treated with ketamine via every RoA over the years, I would assert that the "best way" is the way that is most accessible to any given patient. I wouldn't challenge the studies that show IV is most efficient, most effective, safest but the difference is marginal in my experience. Some of my most transformative experiences have come via sublingual K. Not every patient has access to IV infusions due to geographic or financial barriers. I'd hate to see suffering patients avoid available, affordable local options because they heard on UA-cam that IV is the "best and safest." Every practitioner has their own rationale for why their RoA is best but I'm reminded of a slogan I saw hidden on the wall of the break room at a car dealer, "The right car for your customer is the one that's on the lot!"
best comment. accessibility is the key, and having to have someone licensed to give IV ketamine reduces that drastically. Everything he says about titrating dose and bioavailability is true. But does it justify the cost of paying another licensed professional (hopefully there's already a therapist involved)?
I receive IV ketamine for managing chronic pain from peripheral neuropathy, an in-patient procedure over five days. I'm admitted on Monday afternoon and discharged late Saturday morning. My vital signs are checked every four hours, every two hours for the first eight. For the IV a peripherally inserted central catheter (PICC line) is inserted. That's routinely done for patients as ketamine is viscous and somewhat caustic. Before this I got IV lidocaine, seventy infusions over seven years. Ketamine is much more effective in reducing (not eliminating) the neuropathic pain. I've had ten IV ketamine infusions over three years. The next treatment is in January, four months after my last treatment. Though this use is off-label, the treatment is paid for by Medicare, and I have secondary health insurance coverage. I live in the SF Bay area, and receive treatment at Stanford Hospital.
My only prescription medicine is gabapentin. I take a dozen vitamins and supplements including bromelain, an enzyme from pineapple, for inflammation and magnesium for muscle tension. A bonus was kicking my cigarette habit with the first IV ketamine. Though I hadn't gone in intending to give up that addiction, I'm so glad I did.
I'm given Ketamine via IV during my bone marrow biopsies. It's quite an experience and each time results in an entirely different experience. Because I don't know what to expect, I have a bit of anxiety beforehand. My next biopsy is next week.
@@MedicalSecrets Absolutely, I've tried Ketamine at home, can't find clinic near Olympia/Tacoma, WA. So many now State do in your home, yes doesn't seem work. Will continue looking. You're awesome thanks.
Hi Dr Kaveh, I enjoy the channel so much (PACU RN); periop,by far,has been my career- favourite clinical specialty. I can’t find that you’ve yet done a segment on the potential for anaesthesia, and/or post-operative, complications when one is on Ozempic, Wegovy, etc. It would be timely and important advice for sure! Thanks again for hosting such a quality space on the Internet.
I’ve never heard of this before! I’ve been in constant pain since about 1980! Why doesn’t it get prescribed? Im tired of government ruling over patients getting a pain reliever that works. I was literally on a fentanyl patch(which was iffy for results!) Can I get it by the industrial drum? I need to dunk my Whole Body!
I am so sorry to hear about what you have been through. This is a tricky medication, because it's anti-pain effects may not be achieved with oral dosing. I'll have to do a video specifically on ketamine for chronic pain. In the meantime, do you have somebody helping you cope with your pain?
@@MedicalSecrets my NP is good when she’s not off chasing another type of “religion” or medical type of treatment ( like east/ west) and a bunch of others
I have a couple of questions. Is it possible to provide IV ketamine through a butterfly or does the patient have to have an IV cannula? I have CPTSD that originated during a nine month hospitalization at Stanford in 1971, which included SEMLS and Gallows traction completely without analgesia or muscle spasm control. I then developed osteomyelitis which led to sepsis, blood poisoning, systemic candidiasis and pneumonia. Yeah I come by it honestly. Fast forward to 2023 and I also have severe chronic pain which is going untreated and medication resistant CPTSD related specific phobias, depression and anxiety. Can someone with this type of profile benefit from ketamine therapy? How can someone find a qualified physician practicing in California’s Capital Corridor? I hope you and your loved ones have a wonderful Holiday season. I love your posts.
Was wondering how this is different from fentanyl was given this ( fentanyl )once for a lumbar puncture and passed out and have been given a nerve block before which is scary to wake up to so now I'm scared of stuff like this...
I am interested in this for my step-dad. He has tried so many different medications to help with his depression and PTSD but to no avail. I will talk to him about this treatment.
that's a lot of different things. Serotonin syndrome is a potentially fatal condition that happens when there's too much serotonin activity. This can, for example, happen with MDMA taken along with MAOIs, and maybe MDMA along with SSRIs. MAOIs in general don't combine well with other meds. SSRIs and mushrooms aren't likely to cause serotonin syndrome (check with a doctor don't take the word of a UA-cam comment!), but effects of mushrooms might be diminished. I didn't look too hard but there is a case report of a patient on Prozac (an SSRI) who was given IV ketamine for pain in hospital for 4 days, and had effects consistent with serotonin syndrome.
Just finished 6 iv sessions a few weeks ago. Transformative for tx resist. depression & chronic pain. From bedbound to productive. From years of way behind, interested in maintenance. Appt. to discuss w provider this week. Only way i afforded tx was family support. Interested in cost/benefit potential other modes i might can afford and measures to observe if those tried. Any hints to ask about and/or observe beyond simple affordability & best guessing?
I much appreciated for all usefull infuriations and the way you explained in an easy way . Im going to use this ketamin /10 fir suicide purpose some time soon . And as i understand , we can take it oraly but then we must use really higher dosage . Thanjs a lot . 🙏🙏🙏
I recently broke my femur & the ambulance crew used ketamine. I had never heard of it & they said it’s being used more & more for pain. They were going to do 25 mg, but only got in 10 mg & I got so nauseous that they had to stop. In route to the hospital, they tried to give the remaining dose, but only got in another 5 mg & again it made me super nauseous. Once at hospital, they used dilauded. Is this common, now, to use ketamamine in ambulance patients?
I was getting benefits for the first time with ketamine infusion therapy & I had hope for the first time in decades, but it couldn’t afford to even get one booster so because of the fda protocol… they don’t want us better! I haven’t been living for about 3 decades… I feel I just exist. I have suffered through trying almost every antidepressant and dealt with all the negative effects that many have & I even made sure I was on each medication long enough for me to get full benefits of the medications. I finally had hope for the first time in 2 decades after trying the ketamine infusion therapy only to find out that insurance companies don’t cover anything. $750.00 for each infusion and for me it was $2,250.00 for the first set. I couldn’t afford to get any boosters so my hopes were crushed knowing that what actually was showing promise was not an option
Can ketamine be useful in severe nerve damage pain? A friend fell & had a very severe traumatic hematoma, causing nerve damage due the amount of swelling in the leg & also required multiple blood transfusions due to blood going in to the joint. They had talked about doing surgery on their leg due to compression syndrome?
And once more, I have to tell a medical related channel a big thanks for not actually showing the entire syringe on their thumbnail! I have a phobia of syringes and needles and I’m being triggered at least twice per week in one of the lessons in school or on thumbnails I see on UA-cam. Really, I am grateful that some medical channels don’t go all in for the shock effect. Thanks!❤
I am so sorry to hear about your chronic pain, but that is exactly the strategy that I often advocate for, using the fewest number of treatments for the longest lasting benefit. Thank you so much for sharing your story
@MedicalSecrets thank you for this video I'm lucky to have a boyfriend that was a director of an infusion clinic but people need to know this is out there and it can really help. I also get lidocaine infusions and those are life changers as well. I just wish insurance would pay for them
I've been on spavada (nasal ketamine) for over a year. I don't think it works the same every time, based on my nasal mucous or other factors. I think this is the only form my insurance will cover. What can I do to ensure it works more uniformly?
I'd give anything to be able to try this. I've suffered from depression for too many years. You'd think people like me would be at the front of the line. I've nearly died a few times from this and can't work so I can't afford to have it done. I'd love to work, I'm not lazy, but fibro, CFS and other issues have made it impossible for me. Unfortunately we are so based on profit instead of working towards the well being of all.
I contacted wafermine and they emailed me this evening and said a specialist can prescribe it, and gave me their (wafermines) info to give my Dr to get it worked out. The specialist for me would be a psychiatrist or pain doctor. And I just happened to get a referral to a psychiatrist earlier today. we will see what happens. Email them and see what they say. I just told them how I thought it would help and asked if there is a way to get it since it's still in trials.
I am on over 18 medications, 6 or which are for severe chronic pain, depression and anxiety, one of which is an opioid and is so complicated to get and keep. I wonder if this one medication could replace those medications?! Is it easier to get than opioids? I can fully function on my medications, does Ketamine cause drowsiness, fatigue, does it make you feel loopy?! I am so intrigued!!
These are great questions. In short, I have seen patients reduce their needs for other medications. However, it depends on many factors, especially the wrap around therapies provided to address the root causes of the other conditions. Would you like me to do a video on this topic?
Question? If 15-20% of cardiac output goes to the brain isn’t it an exaggeration that 100% of IV dose goes to the brain? Sorry & Thanks. IV definitely avoids the first pass effect.
@@thekeysman6760 15-20% of cardiac output to brain in probably half minute give or take, but 80-85 percent goes elsewhere first? So it was not exactly correct?
@@stangman962 I get you. Yet now you are conflating oral administration (30 seconds) with intravenous administration (instant). By yeah, I see what you're getting at. And I wouldn't know.
@@thekeysman6760 IV isn’t instant! Probably 15-30 or so seconds arm to brain according to health of patient. Young patient fast while old patient with low ejection fraction slower. Maybe receptor take up and brain activity also delayed with the elderly . I do low dose propofol sedation with a quick bolus daily for eye blocks and find it extremely interesting. 20 or more second onset sleepy 1-2 minutes and awake 3-5 mins. Funny stuff, but effective. Thanks guys!
Sure wish more doctors were like you. Docs nowadays make one feel like the patient is more of an inconvenience especially if you want to confide in them.
I have Anesthesia Dolorosa with the not surprising depression on the side. I am in my 4th year and 2nd year of nasal Ketamine. I had a bad reactive with the nasal, over amount and it was not good and gave me panic and pain I think was a bit higher due to panic. AD really is hard to get pain control. I am better suicidal with time but this is not my dream life.
Yesss. IV ketamine for bioavailability. I get 150mg (10mg bolus) over 50 minutes. My last two surgeries I asked for extra to save me a trip to the ketamine clinic and they were like “sure no problem”
Ketamine is very powerful strong and good when used by an anesthesiologist or emergency room doctor! I really enjoy donating to the anesthesiologist foundation,since it was hard for me to go to college because of my cerebral palsy, I really wanted to be an anesthesiologist! I went to the doctor for my yearly physical exam today, everything check out good! I have to have physical therapy because my muscles are tight because of my cerebral palsy! You been hocking loogies? 😂, I’m still waiting on a date for my eye doctor, they are trying to find a CRNA and anesthesiologist at the surgery center is busy! You rock man! It takes a special person and skills to be a CRNA or anesthesiologist, and you’re one of them, I’m gonna donate to the anesthesiologist foundation again new years
I've gotten ketamine in surgery and recovering from surgery. Some doctors scoff and sat no way will they give me that. But with my cyp450 ultra rapid metabolism of narcotics, this is one that works. However just an IV injection of it only last maybe 10 minutes. Do you have any advice for a patient like me?
Really helpful videos Dr. Kaveh! Sorry I wasn’t able to join due to timing here in the UK. More people should know about this and just how much power we have over our health!Thanks for the information! :)
So at 58yo and looking at bypass in both legs. I have a diagnosis of PTSD,bipolar , clinical depression and anxiety, and MS , degenerative spine and sciatica nerve issues. Not looking forward to this.still haven't been able to make it clear that I will be totally on my own after. Not supposed to drive for a week after. I'm quite rural. I often fight and break things when waking up. The max automatic feed for my animals is four days and no one exposed to them. So many issues outside of the meds and surgery. Thankfully I've worked myself sick and tired pulling my house together from the last roommate that trashed it 2hile I was sick. I did have a small heart attack on the table while they placed the stint in the right side of my heart about 6 months ago. If they knew I drove myself home they wouldn't have been happy. I hired a 2oman off the street to sit in the lobby and tell them she was my driver. Don't think I'll be able to pull that one off again with the next surgery. I'm not afraid of this, just afraid that I won't have everything in order when it gets here. It's no different than preparing to deploy and be dropped in some toilet somewhere that you may not come home from. You make your peace ,prepare for the worst and go do what must be done.that state of mind is almost addicting. The calm ,overwhelming calm. You go fight the battle ,knowing for better or worse you will come out the other end for ever changed. Thank you for what you do. it's like anesthesia boot camp.
I have had chronic pain due to Ehlers Danlos for over 20 years. I’m curious about using ketamine to help with the pain - obviously I have structural issues creating the pain… loose joints and bones that fall out of place easily, but I’ve also had moments on psychedelics where the pain completely disappeared… so I wonder about something like ketamine that supports neuroplasticity helping minimize the pain, even if the source is structural. I hear you saying IV gets better results than oral however I have a severe needle phobia… I get vitamin C IVs occasionally to help my collagen production but I am basically on edge the entire time and don’t nearly get them as frequently as I should just because my nervous system freaks out at the sensation of something puncturing me. So I am super wary to do IV ketamine because there’s no more uncomfortable setting I can imagine than being hooked up to an IV… so in my case, would oral be better? Or have you ever done IV ketamine with someone who gets a panic response at needles and had their body’s response change due to the influence of the drug?
I used to be the same way about shots and especially IV’s but the clinic I go to have such skilled nurses that do my IV that I hardly ever feel it! They use a butterfly IV because I am old and have fragile veins and once you go into the ketamine treatment I have no pain or anxiety unless I have a bad trip, which is unusual and they also give me an anti-anxiety and anti-nausea medicine either in my IV or sometimes the anti-anxiety is given in pill form before starting the ketamine infusion. I have u diagnosed hED and/or Sjogrens Syndrome depending on which of my medical professionals you talk to because they both have lots of the same symptoms. I also have ankylosing spondylitis, osteoarthritis, scoliosis, and MDD and anxiety with PTSD nightmares. The infusion that helps both my chronic pain and emotional disorders is the chronic pain infusion which is 4 hours. The depression/emotional infusion of ketamine for 1 hour do not help me. I hope you get some relief because I know the torment you are going through. At least I think I know.
so if ketamine is given sublingually which contains 10-30% bioavailability, does it take 10 or less sessions of oral ketamine take to get one session of 100% bioavailability of ketamine IV?
I’m a Chronic Pain Patient & been hospitalized 300 days (10months) Chronic Respiratory Failure with Hypoxia & Tracheal Stenosis plus tracheostomy to vent dependent due to Epilepsy/LGS I have my Anesthesiologist/Pain Management Dr & he ordered Fentanyl Patch/Morphine IV 4mgQ4h (33y.o.F) plus over 30+ medically diagnosed Illnesses hEDS,MCAS,POTS,Gastroparesis/TPN 2+yrs dependent over 20+allergies ETC… EXTENSIVE MEDICAL HISTORY but pain is not well controlled if pain increases = hypertension. When PowerPort mlfxing will go hypotensive+ Bradycardia. My Drs & specialist don’t know how to control the pain while being admitted. (CA Resident) SoCal❤ How can we control pain effectively while hospitalized & unable to transfer to SubAcute/Ltac Severe extensive surgical history. Severe case😢 what to do?
I have had ketamine in surgery a coule times. Had such a scary experience with FENTENAYL, UNABLE TO USE IT FOR SURGERY. Because of complex regional pain syndrome, It also did help with the pain syndrome, as well as the anxiety and stress. Last surgery ketamine had NO side affects FROM KETAMINE UNLIKE MANY OTHER DRUGS. THANK YOU
I'm happy to hear that you had a positive outcome. It is a powerful medication when used appropriately, and I hope that we can share knowledge about its responsible use. Is your CRPS under control now?
@@MedicalSecrets IT IS DEFINITELY BETTER. I STILL HAVE HORRIBLE MONSTER EPISODES OF SEVERE CRAMPING AT NIGHT OR DAY THAT DROPS ME TO MY KNEES . . . I HAVE TO STRETCH OUT THE HORRIFIC PAIN. IT IS HORRIBLE WHEN IT FLAIRS. NO LONGER ABLE TO DO WHAT I USED TO DO. VERY ACUTELY AWARE OF HOW MUCH I CAN DO. I TRY TO PACE MYSELF. IT IS DIFFICULT. MANY THINGS TO DO!! A JUGGLING PROCESS. NERVE COMPRESSION OF RT BIG TOE. FRACTURED AND COMPRESSING NERVE.
I want infusions so bad. My CRPS has taken away my ability to walk and I’ve heard this could be life changing. Unfortunately insurance won’t cover it and I can’t afford $15k for those infusions.
The most effective is always going to be straight into the vein. Idc what anyone says. There’s a reason once people pick up the needle, they usually never put it down.
I've had very profound and positive results with oral Ketamine. I live in Oregon. At the moment, Intravenous Ketamine therapy at a clinic is very cost prohibitive for average folks. Oral Ketamine may not be as effective as IV Ketamine but it comes in at abut 1/10th the cost.
Question for you: I watch your channel and I have Ehlers Danlos type 3. You had the episode about how we metabolize meds differently- I learned that the hard way years ago. How do you think it can impact the dosing of ketamine infusions??
Had it for postoperative pain because typical postoperative analgesia didn't relieve my pain. I was so amazed when my pain istantaneously vanished. Then I was tripping hard. The nurse station moved away from me but I didn't feel freaked out by it. Unfortunately, it wore off fast.
So you just increase your oral dosage, is that right? I'm taking ketamine lozenges and my Max dose prescribed was 600 mg. I took 225 and swallowed the medicine at the end of the swishing (around in the mouth) phase and I can tell you that it put me into a complete and total dissociative state for a prolonged period of time. It also cost a fraction of What in infusion would have cost. I'm not chronically depressed or treatment-resistant so I think we're all lozenges are perfect for me. I've also learned that the dissociative state could actually hinder the progress of non chronically depressed and non-treatment resistant individuals such as myself and that I should probably cut my dosage back somewhat.
You can use ketamine infusion therapy for depression? Did I ever have it in surgery? I don’t know because they don’t tell you (and I didn’t ask any they would have told me). But I broke my wrist and in ER they had to set it and the nurse some something about this being used for dates (date drug) and so, what else can that be? I dunno. As a purposeful drug? Like special K or whatever it is called… Absolutely not.
I would like to know if you've been om xanax, and opioids for severe back pain and anxiety for years; will ketamine work instead or with or against these other meds. Thank you.
I had a very bad trip of ketamine when it was administered to me in the ER when I had a compound fracture to my Tib Fib. Personally, did not like the feelings. I felt when coming back out of it because I could feel everything they were doing to my leg. That’s just my experience.
And you felt it due to no localised general anaesthetic in that area, I would guess. Happened to me in operations as well. Safer to under anaesthetise.
@@thekeysman6760 I could feel everything they were doing to my leg and yes Tibia Fibia. Now when they had to do my actual surgery to secure everything they used propofol and it was like having a normal surgery
He’s correct about ketamine. I’ve been receiving ketamine infusions every two weeks for severe crypts. Fibro. Severe degenerative back pain bulging discs etc. depression and anxiety. Also porphyria. I’m a non responder to antidepressants as well. Once been a runner for 30 years and had to stop do to severe body pain and a chielectomy on my right big toe. It helps a great deal. If you can find the right doctors to work together it’s a very helpful tool to have to have a decent quality of life.
I am so happy to hear about the healing you have found. I am wishing you the best in your ongoing healing, and I hope you can inspire others to advocate for their health with your story
Hello, how are you? I have done Ketamine IV for depression and addiction to heroin. I have been on suboxone for 8 years and am lowering my dose slowly. I feel that I will one day be off of it. I have been dependent on stimulants since I was prescribed them at the age of 13. I have tried and tried to live without them but it feels impossible. What do you suggest?
Not sure how to use it , dealing with fibromyalgia and peripheral neuropathy, doctors don't know much about it here india and those who know trying ti charge too much,
I'm so scared for my 24 year old son. He's been dealing with depression and anxiety for years. He's tried venlafaxine a few times and he's also been self-medicating by smoking pot 2 to 3 times a day. He somehow got involved with the ketamine agency that mailed him out a kit and pills to take once a week for 4 weeks. He didn't stop smoking either. A week and a half after starting this ketamine treatment he started really changing personality-wise and now he's telling me I was psychologically abusive to him all his life and that I'm a worthless piece of $hi*. I don't know if it's the ketamine, the combination of ketamine pot and sometimes venlafaxine when he remembers to take it or what but I feel like I've lost my son.
There is no access to Ketamine through IV where I live in Canada. There is a clinic that uses tablets. I have Fibromyalgia and nothing has helped the pain. It’s constant and it’s everywhere. I plan to try it but it is pretty expensive. Should I not bother? I have spent a lot of money over the past 10 years trying different things.
I would do anything to be able to try ketamine but my doctors (Kaiser) say they don't use it and refuse to talk about Ketamine or LDN saying they don't prescribe it or use it. Its damn near impossible to get help for pain if a kaier patient.
When I broke my right ankle, dislocated it and broke my tib fib in 2007, they wanted to set it while I waited surgery as I had eaten. They gave me an IV of Ketamine for conscious sedation. Never again!!! It was like a bad acid trip. Knock me out next time.
I am so sorry to hear that. Unfortunately, ketamine can be given without regards to its other effects. This is why it should be used as part of a multimodal plan in such emergency situations. Are you doing better from your ankle injury?
@@MedicalSecrets That was 15 years ago and I had to have three surgeries over 5 years to correct the problem. First surgery was to put in hardware, a year later second surgery was to get the hardware out. 4 years later I had surgery to clean up a burr and some debris. In 2021, I broke my other ankle and leg. When presenting at hospital for my surgery, the admitting clerk asked me, "is this the same leg you broke before?" I said, " do I look like an idiot? I didn't make the same mistake, I broke the other leg!"😁 Thank you for all that you do. It's important.👍
I've been in pain for over 2 years they've been using bupenorphine 2mgs4xa day I. Was on morphine sulfate for over 8years. My neck is fused back also and hips r failing now.what to do?? 62 yrs old
Hi. Perhaps get on the Live Chat next time so he can answer your question. That sounds pretty rough, brother man. I wish you all the best there. Fused sounds terrible. My friend's mother in her 60s also had a bone crumbling disease and her back just wasted away slowly. Not nice. Be well. 🕊️❤️
@@thekeysman6760 thankyou for the response mine is a special case because of complications due to fusions and ongoing issues . I hope to speak with him, it would be a honor 👍❤️🙏
I'm so sorry to hear about that. It sounds like I need to do a whole video on ketamine for chronic pain. There is evidence for use in complex regional pain syndrome, which I recently described in a video. There is also evidence for neuropathic pain conditions, including phantom limb pain.
It was a really interesting video to watch! Thanks! I am from the EU, Hungary, and I battle with treatment resistant depression for more than a decade now. My insurance! accepted ketamine therapy, but here we only have the Spravato nasal spray. I am on it 3 weeks now and already got really promising effects from it!:) Anyway my point is I weigh 130 kg or 286 pounds and I am 194 cm or 6,36 feet tall male. So one spray contains 28 mg of esketamine. For me one session consists of three 28 mg nasal sprays to achieve the desired effects. My doctor is a neuropsychiatrist so IV is out of question:) But IM too because only vets and anaesthetists have access to it.. But I am more than happy with this nasal form because it WORKS! :) Have a nice day Sir!
I am sorry to hear about what you have been struggling to heal from. It is so in heartening to hear your positive results. I hope you can inspire others also working to heal from treatment resistance depression
Thanks for kind words!:) It means a lot to me as a person who four weeks ago was too anxious to even comment on UA-cam.. I would add a final point to my comment. My progress in healing is not just to the ketamine it is also about finding the right doctor! @@MedicalSecrets
I've had both IV and pills. It's a long drive to a clinic for IV. And expensive. I'm taking the pills now. Now I'm not sure I'm getting what I need. My doctor is following my experience for her practice. She seems quite open-minded about it.
I'm so interested in ketamine infusion for both pain and also depression. Because I can't take SSRI'S due to my metabolism. I get serotonin syndrome within 3 days of even the smallest amount of an ssri. I hate that a person has to be rich to be able to get this treatment. It would be so healing for me.
I am so sorry to hear about what you are struggling to heal from, especially with that predisposition to serotonin syndrome. It sounds like you learned from a bad experience that you had? I am wishing you the best in finding a clinic that will work for you 🙏
@MedicalSecrets my mom always had crazy metabolism and ususual/unexpected reactions to meds but unfortunately she had mental health problems and addiction so she was always just written off as a druggie, and that's why her metabolism was like that. I have the same metabolism and it was evident from childhood. I've never done drugs. I saw something interesting saying that females with autism have unusual and unexpected reactions to medications, that was new info and now I wonder if that might explain it. But the fact is, I'm not a doctor yet I'm having to figure out what's going on in my body myself because doctors just write me off. I'm the patient they dread to see on their schedule. Do you know how that feels? Not good that's for sure.
I did an infusion in 2018. It cured my lifelong anxiety and depression. I am autistic. I didn't know it then though. A single treatment was all it took for me.
Cured me. No other drug or therapy did that. Ketamine heals.
I'm fascinated at your results. I am also autistic, and just started infusion therapy for my treatment resistant depression, PTSD, and chronic pain. I couldn't believe how much better I felt the first week!
I don't feel like the 30mg lozenges do anything, but they tell me I'm not supposed too feel anything, and it's just to keep a baseline level in my system. I was really surprised about the IV experience. I thought I might feel more of an altered state, or hallucinations, or something, and expected to have thoughts or feelings to go over with my therapist. However, the other medications they gave suppress that for some reason, which makes me feel a little cheated on the therapeutic potential.
One thing I noticed is that everyone else said they slept through their infusions. I was reading, watching TV, and doing puzzles. Made me wonder if my dose was low, or if it was just my neurodivergence.
Oh l would love to have this treatment.
Anxiety &depression just sucks the life out of you.
@@bjdefilippo447everyone reacts differently, so I don't think you need to be concerned that you didn't sleep.
Thanks!
A single treatment? Wow. I've had 4 with no effect.
I really appreciate your videos. I have been getting ketamine IV and IM's over the past year and a half, for C-PTSD, depression and anxiety. It has been like a miracle for me. I feel like myself again. I am so grateful for this treatment and hope it will be FDA approved for depression soon. People deserve to know about this drug.
Wow, thank you for sharing this. I’m on the waitlist to start getting ketamine infusions and haven’t been sure what it would be like. This makes me very hopeful!
We need more doctors in congress, imo.
What kind of dr prescribes ketamine therapy? I have heard good things about it. Curious though how this works…….
15:51
Hi Linda, I had the IV yesterday (just one day is given here in the Netherlands) and yesterday my back pain stopped completely, but then today I feel it again. In your case how did the pain stop? Immediately? 😪
I’m currently doing iv treatment for depression after my son died. It’s helping me so much
I am so sorry for your loss. I hope you are finding healing with your current therapy 🙏
🙏 That's amazing.
God will help you we all are with you dear ❤ respect sister
Who needs drugs when you have a medical professional with the voice and disposition of an angel? He makes me feel so chill.
Oh I do agree!!
What a sweetheart Doc! ❤
I totally agree. This anesthesiologist is really one of a kind. I want him for my dr.
I do!.. he is still cool tho
@@brendaeberwein8338
Oh me too!
I’m up by the border in Bellingham Wa.
On disability ( $1347/mo) and they do have 2 new Ketamine treatment centers here in town. But, soon as I mentioned that word to my obviously completely unaware Dr, her tone was that of a shrill freaked sort, like I was looking to get horse trancs, for real.
Did not help me.
I looked into it, and the cost is too high for my pockets and they don’t accept Medicare up front, yet. I’m hoping though in future they will more readily.
It’s established, we are all getting great vibes here anyway. 😊❣️, that goes a long way for me living with chronic pain and anxiety, some depression and bad insomnia.
I watch him and he just makes me feel better ❤️🩹🌻
Pray you all feel better too!!
I do. No voice can soothe the painful truth my hips give me. Wish they could lie to me from time to time to not have pain
I was given ketamine years ago, and felt it was amazing I felt better for a long time. But here, in my state you will not get pain treatment. Question; Is Ketamine addictive? I have Chronic pain, Lupus, absolutely diagnosed neurologic problems throughout my body and so I am looking into going to Colorado to try psychedelics hoping I can get some help. This is tragic that pain is not treated as it wears one out. Thank you Doctor for your kind heart and for educating the masses... We appreciate you!
Thanks for this video. Most information is not given by doctors before surgery. You have empowered us to take action and speak to our doctors!
I did get ketamine infusions. The first time I felt like I would imagine it would feel like if I was dying. It was horrible. Horrid anxiety and nausea. My blood pressure went up to 199/100.
The Dr said not a problem that it will come down. I needed help to get to my car. ( my husband drove me) but horrible experience!! However, the next couple days it was a miracle! I literally felt lighter and even my neighbors noticed. I have severe depression over the loss of my daughter. I went 3 more times at lower dose, then back up to first dose and I never got back to those couple of days I did well. The anxiety and nausea was too much and I couldn't afford to keep going.
Thank you for sharing.
Thank you very much for the information. I've been to a Ketamine infusion clinic for Occipital and Trigeminal Neuralgia. My anesthesiologist is the most compassionate and caring Dr I've ever seen.
I've had initial rounds of IV Ketamine which took all the pain away for 14 days. Unfortunately, my insurance companies refuse to pay for it, so I pay out of pocket for emergencies.
He does also prescribe me oral Ketamine every month which helps me to not have to take addicting and stronger meds nearly as often.
Finding compassionate and well knowledgeable Drs who use Ketamine is a key. Thank you for all you do.
Thank you for sharing your experience. I was recently diagnosed with Trigeminal Neuralgia, and just had my first infusion yesterday through my doctor's office. It was a low dose IV over 4 hours. I had pain through the whole session, which was frustrating, and am not feeling any difference yet. I realize I may need more infusions for it to benefit, but I'm curious about your experience with dosage and length of time for IV? I'm struggling not to get really depressed as well, as this has pretty much limited my life to focusing day and night on some level of pain management, so it feels like higher doses to address that would be helpful as well.
Fellow ON and TN sufferer! Chronic Migraines too. Ketamine has helped me significantly
@jenbraswell8396 - I too have ON & TN and have for 22 years. I went 10 years without a diagnosis. Finally started having pulse radio frequency ablations of the occipital nerve that made it manageable, but it's hard to find a doctor to do them and insurance doesn't cover them. I just finished a round of 6 Ketamine infusions (125 to 250 mg going up 25 each treatment) and they are working well so far, but it's only been 4 days since the last one. Have you tried anything else that has worked for you? I've found that nothing touches the pain and I've tried just about everything. Narcotic meds only help for the short term, but have their own issues.
Doctor you the best. im always excited about this lessons of ketamine. thank you so much you the best.
I'm so happy to hear that!
Both my family doc and my pain doc have recommended Ketamine for my depression and chronic pain, both caused by my MS. I cannot afford it though, so I am unable to see if it will work. The cost and unavailability just add to my depression.
There are so many instances proving that it helps people with such a variety of things. I really hope that it is covered by insurance soon. The out of pocket cost is insane!!
I'd like to try it for several of my issues, but I can't afford it either. I also can't get any other kind of help. So I'm just stuck suffering 🙃
Something needs to change soon. I hope we can get access to it reasonably in the future 🙏
@@HiKingMargo I hope you're right! I am so sorry for your suffering without any relief. I can empathize. Take as care as much as you are able. 🥰
Suffered and suffering anxiety and depression.
Would love to have infusions...unfortunately it is unaffordable for most people.
But thank you for you sharing this information. ❤️
Try spray!
Thank you so much for explaining! This video showed me you really listened to the results of your recent survey as to what people really want to learn about. Awesome!
Thank you for this well-timed video! My pain management team recommended I try ketamine infusions, and I did not know much about it. I appreciate you sharing your knowledge.
I am so sorry to hear about your chronic pain. Have you started the infusions yet?
@@MedicalSecrets I’m on the waitlist, so hopefully soon. Thank you for being such a caring person 💜
When I had gallbladder surgery, I actually needed so much and many different narcotics. I have to have such large doses of ketamine, fentanyl and versed because I literally detoxify those drugs so fast so it makes everything risky! I have amnesia so I don’t remember how the ketamine was administered. If my surgery was only like a 5 minute scope test I can probably get away with using propofol but anything that takes longer than 5 minutes, I will need something stronger than propofol. I didn’t want to risk waking up during surgery again while having my sternum cut open so I went without sleep and marijuana and I had the anesthesiologist give me ketamine.
Having been treated with ketamine via every RoA over the years, I would assert that the "best way" is the way that is most accessible to any given patient. I wouldn't challenge the studies that show IV is most efficient, most effective, safest but the difference is marginal in my experience. Some of my most transformative experiences have come via sublingual K. Not every patient has access to IV infusions due to geographic or financial barriers. I'd hate to see suffering patients avoid available, affordable local options because they heard on UA-cam that IV is the "best and safest."
Every practitioner has their own rationale for why their RoA is best but I'm reminded of a slogan I saw hidden on the wall of the break room at a car dealer, "The right car for your customer is the one that's on the lot!"
best comment. accessibility is the key, and having to have someone licensed to give IV ketamine reduces that drastically.
Everything he says about titrating dose and bioavailability is true. But does it justify the cost of paying another licensed professional (hopefully there's already a therapist involved)?
I receive IV ketamine for managing chronic pain from peripheral neuropathy, an in-patient procedure over five days. I'm admitted on Monday afternoon and discharged late Saturday morning. My vital signs are checked every four hours, every two hours for the first eight.
For the IV a peripherally inserted central catheter (PICC line) is inserted. That's routinely done for patients as ketamine is viscous and somewhat caustic.
Before this I got IV lidocaine, seventy infusions over seven years. Ketamine is much more effective in reducing (not eliminating) the neuropathic pain.
I've had ten IV ketamine infusions over three years. The next treatment is in January, four months after my last treatment.
Though this use is off-label, the treatment is paid for by Medicare, and I have secondary health insurance coverage.
I live in the SF Bay area, and receive treatment at Stanford Hospital.
Thanks, I was wondering if Medicare covered it.
My only prescription medicine is gabapentin.
I take a dozen vitamins and supplements including bromelain, an enzyme from pineapple, for inflammation and magnesium for muscle tension.
A bonus was kicking my cigarette habit with the first IV ketamine. Though I hadn't gone in intending to give up that addiction, I'm so glad I did.
@@RobG1729 gabapentin scares me, so I only take it a few days per month.
It leaches out calcium, and has rotted my friend's teeth out.
I'm given Ketamine via IV during my bone marrow biopsies. It's quite an experience and each time results in an entirely different experience. Because I don't know what to expect, I have a bit of anxiety beforehand. My next biopsy is next week.
You are so lucky to have pain relief for biopsies I was given nothing and it was so painful and I felt them removing the bone biopsies 😢.
Yes. Each trip is different. But I strap in like I am going on a circus ride.
I love the feeling of coming out of my prison of my body and fly 🕊️🙏
Seems I keep missing you live Doc, always catch late. Love this channel. ❤😊
Thank you for the kind comments! I hope you learned something new to advocate for your health 🙏
@@MedicalSecrets
Absolutely, I've tried Ketamine at home, can't find clinic near Olympia/Tacoma, WA. So many now State do in your home, yes doesn't seem work. Will continue looking. You're awesome thanks.
Hi Dr Kaveh, I enjoy the channel so much (PACU RN); periop,by far,has been my career- favourite clinical specialty.
I can’t find that you’ve yet done a segment on the potential for anaesthesia, and/or post-operative, complications when one is on Ozempic, Wegovy, etc. It would be timely and important advice for sure! Thanks again for hosting such a quality space on the Internet.
Does Ketamine work for severe OCD?? I’ve tried every kind of medication and I’m desperate for something that works.
I’ve never heard of this before! I’ve been in constant pain since about 1980! Why doesn’t it get prescribed? Im tired of government ruling over patients getting a pain reliever that works. I was literally on a fentanyl patch(which was iffy for results!)
Can I get it by the industrial drum? I need to dunk my Whole Body!
I am so sorry to hear about what you have been through. This is a tricky medication, because it's anti-pain effects may not be achieved with oral dosing. I'll have to do a video specifically on ketamine for chronic pain. In the meantime, do you have somebody helping you cope with your pain?
@@MedicalSecrets my NP is good when she’s not off chasing another type of “religion” or medical type of treatment ( like east/ west) and a bunch of others
Thank you for your informative videos. Anesthesia is one of my favorite medical (and nursing) specialties. 😊
Thank you for continuing to sharing your heart and knowledge. ❤
I have a couple of questions.
Is it possible to provide IV ketamine through a butterfly or does the patient have to have an IV cannula?
I have CPTSD that originated during a nine month hospitalization at Stanford in 1971, which included SEMLS and Gallows traction completely without analgesia or muscle spasm control. I then developed osteomyelitis which led to sepsis, blood poisoning, systemic candidiasis and pneumonia.
Yeah I come by it honestly.
Fast forward to 2023 and I also have severe chronic pain which is going untreated and medication resistant CPTSD related specific phobias, depression and anxiety.
Can someone with this type of profile benefit from ketamine therapy?
How can someone find a qualified physician practicing in California’s Capital Corridor?
I hope you and your loved ones have a wonderful Holiday season.
I love your posts.
Was wondering how this is different from fentanyl was given this ( fentanyl )once for a lumbar puncture and passed out and have been given a nerve block before which is scary to wake up to so now I'm scared of stuff like this...
I am interested in this for my step-dad. He has tried so many different medications to help with his depression and PTSD but to no avail. I will talk to him about this treatment.
I’ve suffered headaches due to head trauma as a child that’s why I have had headaches all my life
Must rule out serotonin syndrome before administering ketamine or psilocybin, or prescribing SSRIs, Tricyclics, or MAO inhibitors.
True nobody thinks about this but yeah I've had serotonin syndrome from taking ssrs
@@KseniaHazaelCan I ask what it felt like
that's a lot of different things.
Serotonin syndrome is a potentially fatal condition that happens when there's too much serotonin activity. This can, for example, happen with MDMA taken along with MAOIs, and maybe MDMA along with SSRIs.
MAOIs in general don't combine well with other meds.
SSRIs and mushrooms aren't likely to cause serotonin syndrome (check with a doctor don't take the word of a UA-cam comment!), but effects of mushrooms might be diminished.
I didn't look too hard but there is a case report of a patient on Prozac (an SSRI) who was given IV ketamine for pain in hospital for 4 days, and had effects consistent with serotonin syndrome.
Just finished 6 iv sessions a few weeks ago. Transformative for tx resist. depression & chronic pain. From bedbound to productive. From years of way behind, interested in maintenance. Appt. to discuss w provider this week. Only way i afforded tx was family support. Interested in cost/benefit potential other modes i might can afford and measures to observe if those tried. Any hints to ask about and/or observe beyond simple affordability & best guessing?
I much appreciated for all usefull infuriations and the way you explained in an easy way .
Im going to use this ketamin /10 fir suicide purpose some time soon .
And as i understand , we can take it oraly but then we must use really higher dosage .
Thanjs a lot .
🙏🙏🙏
I love your channel. I watch it all the time
I recently broke my femur & the ambulance crew used ketamine. I had never heard of it & they said it’s being used more & more for pain. They were going to do 25 mg, but only got in 10 mg & I got so nauseous that they had to stop. In route to the hospital, they tried to give the remaining dose, but only got in another 5 mg & again it made me super nauseous. Once at hospital, they used dilauded. Is this common, now, to use ketamamine in ambulance patients?
I just want my daughter back and nothing can help that.😢
I was getting benefits for the first time with ketamine infusion therapy & I had hope for the first time in decades, but it couldn’t afford to even get one booster so because of the fda protocol… they don’t want us better!
I haven’t been living for about 3 decades… I feel I just exist. I have suffered through trying almost every antidepressant and dealt with all the negative effects that many have & I even made sure I was on each medication long enough for me to get full benefits of the medications. I finally had hope for the first time in 2 decades after trying the ketamine infusion therapy only to find out that insurance companies don’t cover anything. $750.00 for each infusion and for me it was $2,250.00 for the first set. I couldn’t afford to get any boosters so my hopes were crushed knowing that what actually was showing promise was not an option
Insurance is the BIGGEST SCAM RIP OFF EVER !! It should cover WHATEVER will help the patient. Our Government wants us dead ☠️
Six sessions of ketamine IV for my drug resistant depression. Worked for a while…
Can ketamine be useful in severe nerve damage pain? A friend fell & had a very severe traumatic hematoma, causing nerve damage due the amount of swelling in the leg & also required multiple blood transfusions due to blood going in to the joint. They had talked about doing surgery on their leg due to compression syndrome?
And once more, I have to tell a medical related channel a big thanks for not actually showing the entire syringe on their thumbnail! I have a phobia of syringes and needles and I’m being triggered at least twice per week in one of the lessons in school or on thumbnails I see on UA-cam. Really, I am grateful that some medical channels don’t go all in for the shock effect.
Thanks!❤
Maybe the medical field isn't for you, bud.
Ketamine infusions have saved me from my chronic pain. We have sublingual as well and its for inbetween infusions so they last a bit longer
I am so sorry to hear about your chronic pain, but that is exactly the strategy that I often advocate for, using the fewest number of treatments for the longest lasting benefit. Thank you so much for sharing your story
@MedicalSecrets thank you for this video I'm lucky to have a boyfriend that was a director of an infusion clinic but people need to know this is out there and it can really help. I also get lidocaine infusions and those are life changers as well. I just wish insurance would pay for them
You are awesome!!!
I've been on spavada (nasal ketamine) for over a year. I don't think it works the same every time, based on my nasal mucous or other factors. I think this is the only form my insurance will cover.
What can I do to ensure it works more uniformly?
Worst damn drug I've ever been given in a hospital. If
you like hallucinations,
You'll like this stuff. It's awhile
Would Ketamine be safe for a pt with Malignant Hyperthermia? Thank you for your time!
I'd give anything to be able to try this. I've suffered from depression for too many years. You'd think people like me would be at the front of the line. I've nearly died a few times from this and can't work so I can't afford to have it done. I'd love to work, I'm not lazy, but fibro, CFS and other issues have made it impossible for me. Unfortunately we are so based on profit instead of working towards the well being of all.
I contacted wafermine and they emailed me this evening and said a specialist can prescribe it, and gave me their (wafermines) info to give my Dr to get it worked out. The specialist for me would be a psychiatrist or pain doctor. And I just happened to get a referral to a psychiatrist earlier today. we will see what happens. Email them and see what they say. I just told them how I thought it would help and asked if there is a way to get it since it's still in trials.
Maybe try the nasal spray. Although it’s not the ideal as the doctor explains in the video, it still helped me with fibro, depression and anxiety
I am on over 18 medications, 6 or which are for severe chronic pain, depression and anxiety, one of which is an opioid and is so complicated to get and keep. I wonder if this one medication could replace those medications?! Is it easier to get than opioids? I can fully function on my medications, does Ketamine cause drowsiness, fatigue, does it make you feel loopy?! I am so intrigued!!
These are great questions. In short, I have seen patients reduce their needs for other medications. However, it depends on many factors, especially the wrap around therapies provided to address the root causes of the other conditions. Would you like me to do a video on this topic?
I just subscribed, because he is so easy to understand, and I appreciate his honesty and caring demeanor. Oh, and also, he’s not hard to look at lol.
Question? If 15-20% of cardiac output goes to the brain isn’t it an exaggeration that 100% of IV dose goes to the brain? Sorry & Thanks. IV definitely avoids the first pass effect.
I'm still waiting to hear this being said. I heard "straight to the brain in seconds". Maybe I missed it.
Got it! 🤦♂️Back near the start before the 4 minute mark. Yes, interesting.
@@thekeysman6760 15-20% of cardiac output to brain in probably half minute give or take, but 80-85 percent goes elsewhere first? So it was not exactly correct?
@@stangman962 I get you. Yet now you are conflating oral administration (30 seconds) with intravenous administration (instant). By yeah, I see what you're getting at. And I wouldn't know.
@@thekeysman6760 IV isn’t instant! Probably 15-30 or so seconds arm to brain according to health of patient. Young patient fast while old patient with low ejection fraction slower. Maybe receptor take up and brain activity also delayed with the elderly . I do low dose propofol sedation with a quick bolus daily for eye blocks and find it extremely interesting. 20 or more second onset sleepy 1-2 minutes and awake 3-5 mins. Funny stuff, but effective. Thanks guys!
Sure wish more doctors were like you. Docs nowadays make one feel like the patient is more of an inconvenience especially if you want to confide in them.
I have Anesthesia Dolorosa with the not surprising depression on the side. I am in my 4th year and 2nd year of nasal Ketamine. I had a bad reactive with the nasal, over amount and it was not good and gave me panic and pain I think was a bit higher due to panic. AD really is hard to get pain control. I am better suicidal with time but this is not my dream life.
How do I tell the difference between a legitimate and non legitimate Doctor or Clinic ?
The doctor covered some of that in an earlier video.
ua-cam.com/video/wd9Optc3ido/v-deo.htmlsi=tjQuMksr0_ZoKb1S
when one day (one pill) = $3 versa one treatment IV at a clinic for $1500, well I will take the generic Oral dose any day lol
Yesss. IV ketamine for bioavailability. I get 150mg (10mg bolus) over 50 minutes. My last two surgeries I asked for extra to save me a trip to the ketamine clinic and they were like “sure no problem”
I am allergic to anesthesia. I want toco e toSan Francisco to see you. How do I reach you?
True IV is most controllable and predictable. But nasal is $50 and IV is $600.
Ketamine is very powerful strong and good when used by an anesthesiologist or emergency room doctor! I really enjoy donating to the anesthesiologist foundation,since it was hard for me to go to college because of my cerebral palsy, I really wanted to be an anesthesiologist! I went to the doctor for my yearly physical exam today, everything check out good! I have to have physical therapy because my muscles are tight because of my cerebral palsy! You been hocking loogies? 😂, I’m still waiting on a date for my eye doctor, they are trying to find a CRNA and anesthesiologist at the surgery center is busy! You rock man! It takes a special person and skills to be a CRNA or anesthesiologist, and you’re one of them, I’m gonna donate to the anesthesiologist foundation again new years
I had the most AMAZING Ketamine therapy ever.
It calmed my pain for a long time and it bounced me right out of depression.
I am a fan.
I've gotten ketamine in surgery and recovering from surgery. Some doctors scoff and sat no way will they give me that. But with my cyp450 ultra rapid metabolism of narcotics, this is one that works. However just an IV injection of it only last maybe 10 minutes. Do you have any advice for a patient like me?
Really helpful videos Dr. Kaveh! Sorry I wasn’t able to join due to timing here in the UK. More people should know about this and just how much power we have over our health!Thanks for the information! :)
If ketamine is not monitored carefully during an operation I presume that it can cause damage to the nervous system then. Would that be fair to say?
So at 58yo and looking at bypass in both legs. I have a diagnosis of PTSD,bipolar , clinical depression and anxiety, and MS , degenerative spine and sciatica nerve issues. Not looking forward to this.still haven't been able to make it clear that I will be totally on my own after. Not supposed to drive for a week after. I'm quite rural. I often fight and break things when waking up. The max automatic feed for my animals is four days and no one exposed to them. So many issues outside of the meds and surgery. Thankfully I've worked myself sick and tired pulling my house together from the last roommate that trashed it 2hile I was sick. I did have a small heart attack on the table while they placed the stint in the right side of my heart about 6 months ago. If they knew I drove myself home they wouldn't have been happy. I hired a 2oman off the street to sit in the lobby and tell them she was my driver. Don't think I'll be able to pull that one off again with the next surgery. I'm not afraid of this, just afraid that I won't have everything in order when it gets here. It's no different than preparing to deploy and be dropped in some toilet somewhere that you may not come home from. You make your peace ,prepare for the worst and go do what must be done.that state of mind is almost addicting. The calm ,overwhelming calm. You go fight the battle ,knowing for better or worse you will come out the other end for ever changed. Thank you for what you do. it's like anesthesia boot camp.
I'm depressed after watching the Covid killings, will it help me?
I have had chronic pain due to Ehlers Danlos for over 20 years. I’m curious about using ketamine to help with the pain - obviously I have structural issues creating the pain… loose joints and bones that fall out of place easily, but I’ve also had moments on psychedelics where the pain completely disappeared… so I wonder about something like ketamine that supports neuroplasticity helping minimize the pain, even if the source is structural.
I hear you saying IV gets better results than oral however I have a severe needle phobia… I get vitamin C IVs occasionally to help my collagen production but I am basically on edge the entire time and don’t nearly get them as frequently as I should just because my nervous system freaks out at the sensation of something puncturing me. So I am super wary to do IV ketamine because there’s no more uncomfortable setting I can imagine than being hooked up to an IV… so in my case, would oral be better? Or have you ever done IV ketamine with someone who gets a panic response at needles and had their body’s response change due to the influence of the drug?
I used to be the same way about shots and especially IV’s but the clinic I go to have such skilled nurses that do my IV that I hardly ever feel it! They use a butterfly IV because I am old and have fragile veins and once you go into the ketamine treatment I have no pain or anxiety unless I have a bad trip, which is unusual and they also give me an anti-anxiety and anti-nausea medicine either in my IV or sometimes the anti-anxiety is given in pill form before starting the ketamine infusion. I have u diagnosed hED and/or Sjogrens Syndrome depending on which of my medical professionals you talk to because they both have lots of the same symptoms. I also have ankylosing spondylitis, osteoarthritis, scoliosis, and MDD and anxiety with PTSD nightmares. The infusion that helps both my chronic pain and emotional disorders is the chronic pain infusion which is 4 hours. The depression/emotional infusion of ketamine for 1 hour do not help me. I hope you get some relief because I know the torment you are going through. At least I think I know.
so if ketamine is given sublingually which contains 10-30% bioavailability, does it take 10 or less sessions of oral ketamine take to get one session of 100% bioavailability of ketamine IV?
Matthew Perry died from effects of drug ketamine, coroner says
I’m a Chronic Pain Patient & been hospitalized 300 days (10months) Chronic Respiratory Failure with Hypoxia & Tracheal Stenosis plus tracheostomy to vent dependent due to Epilepsy/LGS I have my Anesthesiologist/Pain Management Dr & he ordered Fentanyl Patch/Morphine IV 4mgQ4h (33y.o.F) plus over 30+ medically diagnosed Illnesses hEDS,MCAS,POTS,Gastroparesis/TPN 2+yrs dependent over 20+allergies ETC… EXTENSIVE MEDICAL HISTORY but pain is not well controlled if pain increases = hypertension. When PowerPort mlfxing will go hypotensive+ Bradycardia. My Drs & specialist don’t know how to control the pain while being admitted. (CA Resident) SoCal❤ How can we control pain effectively while hospitalized & unable to transfer to SubAcute/Ltac Severe extensive surgical history. Severe case😢 what to do?
I have had ketamine in surgery a coule times. Had such a scary experience with FENTENAYL, UNABLE TO USE IT FOR SURGERY. Because of complex regional pain syndrome, It also did help with the pain syndrome, as well as the anxiety and stress. Last surgery ketamine had NO side affects FROM KETAMINE UNLIKE MANY OTHER DRUGS.
THANK YOU
I'm happy to hear that you had a positive outcome. It is a powerful medication when used appropriately, and I hope that we can share knowledge about its responsible use. Is your CRPS under control now?
@@MedicalSecrets IT IS DEFINITELY BETTER. I STILL HAVE HORRIBLE MONSTER EPISODES OF SEVERE CRAMPING AT NIGHT OR DAY THAT DROPS ME TO MY KNEES . . . I HAVE TO STRETCH OUT THE HORRIFIC PAIN. IT IS HORRIBLE WHEN IT FLAIRS. NO LONGER ABLE TO DO WHAT I USED TO DO. VERY ACUTELY AWARE OF HOW MUCH I CAN DO. I TRY TO PACE MYSELF. IT IS DIFFICULT. MANY THINGS TO DO!! A JUGGLING PROCESS. NERVE COMPRESSION OF RT BIG TOE. FRACTURED AND COMPRESSING NERVE.
I have it when I had cervical spine surgery it was 4 hours long and I only know because I look on my chart
It is often used in spine surgeries because of its anti-pain properties. How did your surgery go? How was your recovery?
Probably I have had 50-55 major majors surgeries since I was born and I am 51 years old now so I would say yes in 51 years of living!!!! 🎉😅😂🎉❤😮
I want infusions so bad. My CRPS has taken away my ability to walk and I’ve heard this could be life changing. Unfortunately insurance won’t cover it and I can’t afford $15k for those infusions.
The most effective is always going to be straight into the vein. Idc what anyone says. There’s a reason once people pick up the needle, they usually never put it down.
I've had very profound and positive results with oral Ketamine. I live in Oregon. At the moment, Intravenous Ketamine therapy at a clinic is very cost prohibitive for average folks. Oral Ketamine may not be as effective as IV Ketamine but it comes in at abut 1/10th the cost.
Question for you: I watch your channel and I have Ehlers Danlos type 3. You had the episode about how we metabolize meds differently- I learned that the hard way years ago. How do you think it can impact the dosing of ketamine infusions??
Had it for postoperative pain because typical postoperative analgesia didn't relieve my pain.
I was so amazed when my pain istantaneously vanished. Then I was tripping hard. The nurse station moved away from me but I didn't feel freaked out by it.
Unfortunately, it wore off fast.
So you just increase your oral dosage, is that right? I'm taking ketamine lozenges and my Max dose prescribed was 600 mg. I took 225 and swallowed the medicine at the end of the swishing (around in the mouth) phase and I can tell you that it put me into a complete and total dissociative state for a prolonged period of time. It also cost a fraction of What in infusion would have cost. I'm not chronically depressed or treatment-resistant so I think we're all lozenges are perfect for me. I've also learned that the dissociative state could actually hinder the progress of non chronically depressed and non-treatment resistant individuals such as myself and that I should probably cut my dosage back somewhat.
You can use ketamine infusion therapy for depression?
Did I ever have it in surgery? I don’t know because they don’t tell you (and I didn’t ask any they would have told me). But I broke my wrist and in ER they had to set it and the nurse some something about this being used for dates (date drug) and so, what else can that be? I dunno.
As a purposeful drug? Like special K or whatever it is called… Absolutely not.
I would like to know if you've been om xanax, and opioids for severe back pain and anxiety for years; will ketamine work instead or with or against these other meds. Thank you.
What is esketamine? I have no relief from anti depressants. I’m not asking for advice. Just want to know what it is. ❤️ Happy Holidays!!
I had a very bad trip of ketamine when it was administered to me in the ER when I had a compound fracture to my Tib Fib. Personally, did not like the feelings. I felt when coming back out of it because I could feel everything they were doing to my leg. That’s just my experience.
Does it make you feel disorientated? I’m sorry to hear of your experience. How are you now ?
@jeremywhite Do you refer to tibia and fibula when you say "Tib Fib"?
And you felt it due to no localised general anaesthetic in that area, I would guess. Happened to me in operations as well. Safer to under anaesthetise.
@@thekeysman6760 yes that is the short term for it ..
@@thekeysman6760 I could feel everything they were doing to my leg and yes Tibia Fibia. Now when they had to do my actual surgery to secure everything they used propofol and it was like having a normal surgery
If only infusions were as affordable as oral.
He’s correct about ketamine. I’ve been receiving ketamine infusions every two weeks for severe crypts. Fibro. Severe degenerative back pain bulging discs etc. depression and anxiety. Also porphyria. I’m a non responder to antidepressants as well. Once been a runner for 30 years and had to stop do to severe body pain and a chielectomy on my right big toe. It helps a great deal. If you can find the right doctors to work together it’s a very helpful tool to have to have a decent quality of life.
I am so happy to hear about the healing you have found. I am wishing you the best in your ongoing healing, and I hope you can inspire others to advocate for their health with your story
Hello, how are you?
I have done Ketamine IV for depression and addiction to heroin. I have been on suboxone for 8 years and am lowering my dose slowly. I feel that I will one day be off of it.
I have been dependent on stimulants since I was prescribed them at the age of 13.
I have tried and tried to live without them but it feels impossible. What do you suggest?
Not sure how to use it , dealing with fibromyalgia and peripheral neuropathy, doctors don't know much about it here india and those who know trying ti charge too much,
I'm so scared for my 24 year old son. He's been dealing with depression and anxiety for years. He's tried venlafaxine a few times and he's also been self-medicating by smoking pot 2 to 3 times a day. He somehow got involved with the ketamine agency that mailed him out a kit and pills to take once a week for 4 weeks. He didn't stop smoking either. A week and a half after starting this ketamine treatment he started really changing personality-wise and now he's telling me I was psychologically abusive to him all his life and that I'm a worthless piece of $hi*. I don't know if it's the ketamine, the combination of ketamine pot and sometimes venlafaxine when he remembers to take it or what but I feel like I've lost my son.
There is no access to Ketamine through IV where I live in Canada. There is a clinic that uses tablets. I have Fibromyalgia and nothing has helped the pain. It’s constant and it’s everywhere. I plan to try it but it is pretty expensive. Should I not bother? I have spent a lot of money over the past 10 years trying different things.
I would do anything to be able to try ketamine but my doctors (Kaiser) say they don't use it and refuse to talk about Ketamine or LDN saying they don't prescribe it or use it. Its damn near impossible to get help for pain if a kaier patient.
Is't that a hallucinogenic dru😢
i can’t and won’t answer for Dr. , but i will say it is, but this is microdosed and managed in a way no narcotic ever is.
When I broke my right ankle, dislocated it and broke my tib fib in 2007, they wanted to set it while I waited surgery as I had eaten. They gave me an IV of Ketamine for conscious sedation. Never again!!! It was like a bad acid trip. Knock me out next time.
I am so sorry to hear that. Unfortunately, ketamine can be given without regards to its other effects. This is why it should be used as part of a multimodal plan in such emergency situations. Are you doing better from your ankle injury?
@@MedicalSecrets That was 15 years ago and I had to have three surgeries over 5 years to correct the problem. First surgery was to put in hardware, a year later second surgery was to get the hardware out. 4 years later I had surgery to clean up a burr and some debris. In 2021, I broke my other ankle and leg. When presenting at hospital for my surgery, the admitting clerk asked me, "is this the same leg you broke before?" I said, " do I look like an idiot? I didn't make the same mistake, I broke the other leg!"😁
Thank you for all that you do. It's important.👍
I've been in pain for over 2 years they've been using bupenorphine 2mgs4xa day I. Was on morphine sulfate for over 8years.
My neck is fused back
also and hips r failing now.what to do?? 62 yrs old
Hi. Perhaps get on the Live Chat next time so he can answer your question. That sounds pretty rough, brother man. I wish you all the best there. Fused sounds terrible. My friend's mother in her 60s also had a bone crumbling disease and her back just wasted away slowly. Not nice. Be well. 🕊️❤️
@@thekeysman6760 thankyou for the response mine is a special case because of complications due to fusions and ongoing issues . I hope to speak with him, it would be a honor 👍❤️🙏
I am a chronic pain patient... how can this help us who have ongoing pain and dont want to be on daily opioids?
I'm so sorry to hear about that. It sounds like I need to do a whole video on ketamine for chronic pain. There is evidence for use in complex regional pain syndrome, which I recently described in a video. There is also evidence for neuropathic pain conditions, including phantom limb pain.
It was a really interesting video to watch! Thanks! I am from the EU, Hungary, and I battle with treatment resistant depression for more than a decade now. My insurance! accepted ketamine therapy, but here we only have the Spravato nasal spray. I am on it 3 weeks now and already got really promising effects from it!:) Anyway my point is I weigh 130 kg or 286 pounds and I am 194 cm or 6,36 feet tall male. So one spray contains 28 mg of esketamine. For me one session consists of three 28 mg nasal sprays to achieve the desired effects. My doctor is a neuropsychiatrist so IV is out of question:) But IM too because only vets and anaesthetists have access to it.. But I am more than happy with this nasal form because it WORKS! :)
Have a nice day Sir!
I am sorry to hear about what you have been struggling to heal from. It is so in heartening to hear your positive results. I hope you can inspire others also working to heal from treatment resistance depression
Thanks for kind words!:) It means a lot to me as a person who four weeks ago was too anxious to even comment on UA-cam.. I would add a final point to my comment. My progress in healing is not just to the ketamine it is also about finding the right doctor! @@MedicalSecrets
I've had both IV and pills. It's a long drive to a clinic for IV. And expensive. I'm taking the pills now. Now I'm not sure I'm getting what I need.
My doctor is following my experience for her practice. She seems quite open-minded about it.
Do you take them daily?
@@ashatan4554 No. Once a week to 10 days on a program called Mindbloom. Doctor monitored.
My doctor wants to put me on this for depression
A lot of teleological explanations for why IV is better. How about data?
I'm so interested in ketamine infusion for both pain and also depression. Because I can't take SSRI'S due to my metabolism. I get serotonin syndrome within 3 days of even the smallest amount of an ssri. I hate that a person has to be rich to be able to get this treatment. It would be so healing for me.
I am so sorry to hear about what you are struggling to heal from, especially with that predisposition to serotonin syndrome. It sounds like you learned from a bad experience that you had? I am wishing you the best in finding a clinic that will work for you 🙏
@MedicalSecrets my mom always had crazy metabolism and ususual/unexpected reactions to meds but unfortunately she had mental health problems and addiction so she was always just written off as a druggie, and that's why her metabolism was like that. I have the same metabolism and it was evident from childhood. I've never done drugs. I saw something interesting saying that females with autism have unusual and unexpected reactions to medications, that was new info and now I wonder if that might explain it. But the fact is, I'm not a doctor yet I'm having to figure out what's going on in my body myself because doctors just write me off. I'm the patient they dread to see on their schedule. Do you know how that feels? Not good that's for sure.
Can Ketamine go with Diazepam? thankyou for your information
7 years depression free after starting Ketamine infusions. About 7 infusions per year.
PLEASE! My daughter needs this treatment urgente, she lives in Maryland! Any información as to a Doctor who does this treatment in Maryland??
Im scared to do it bc how ot makes you feel while getting it. I wish i could be knocked our :)
I so want to try this. No place around does this. LSD helped me in the 70’s.
Does ketamine stop that pain loop from CRPS ? Thank you
Dr, please make a video on toxicity of ketamine