What causes antibiotic resistance? - Kevin Wu

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  • Опубліковано 6 сер 2014
  • Explore how bacteria become resistant to antibiotics and turn into superbugs, and what scientists are doing to stop it.
    --
    Right now, you are inhabited by trillions of microorganisms. Many of these bacteria are harmless (or even helpful!), but there are a few strains of ‘super bacteria’ that are pretty nasty -- and they’re growing resistant to our antibiotics. Why is this happening? Kevin Wu details the evolution of this problem that presents a big challenge for the future of medicine.
    Lesson by Kevin Wu, animation by Brett Underhill.
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    View full lesson: ed.ted.com/lessons/how-antibio...

КОМЕНТАРІ • 1,4 тис.

  • @gobzanuff5078
    @gobzanuff5078 7 років тому +1809

    We need to train our bacteria to fight other bacteria...

    • @gwiber282
      @gwiber282 5 років тому +104

      They do it already. Many (most, I think) antibiotics are produced by other bacteria or are semisynthetic versions of those that are.

    • @markyoung614
      @markyoung614 5 років тому +10

      He’s taking about the bacteria fighting each other without phages

    • @avi8aviate
      @avi8aviate 5 років тому +21

      Or use viruses to do it for us. In fact, that's already been done!

    • @marcsmoo
      @marcsmoo 5 років тому +16

      Bacteria boot camp

    • @lightning1254
      @lightning1254 4 роки тому +7

      the bacteria of our body are already fighting the pathogenic bacteria...this the first line defence of our body

  • @gshak33
    @gshak33 9 років тому +952

    They don't even mention how the meat industry's overuse of antibiotics is greatly speeding this up cause that would probably be a whole other video.

    • @lokii3970
      @lokii3970 6 років тому +38

      more than likely, since its only glancing over the surface, however, kurzegsagt - in a nutshell did mention this in their video over "antibiotics" as well, but still merely a glance at it.

    • @LAinLA86
      @LAinLA86 6 років тому +7

      It would political since Republicans dont want to do anything about it

    • @Pongi626
      @Pongi626 6 років тому +25

      Gabe Shakour meat isn't healthy anyway. there are tons of studies on why plant based is healthier for humans.

    • @fan-mix6556
      @fan-mix6556 5 років тому +5

      Gabe Shakour
      any kind of antibiotics overuse/abuse/misuse will cause this!

    • @verifeli
      @verifeli 5 років тому

      +Pterodactyl: Well, now you know why some ancient fairytale books forbids eating meat.

  • @debhere4608
    @debhere4608 3 роки тому +850

    Who's teacher sent them here?

  • @bayarsaikhanbaasanbat9009
    @bayarsaikhanbaasanbat9009 8 років тому +463

    I love the bacteria farting part. very creative!

  • @TrueCorventus
    @TrueCorventus 10 років тому +167

    It would be awesome that this and other Ted-Ed videos would have subtitles for other languages as well, specifically Spanish for more viewers to understand. These truly are lessons worth sharing.

  • @donttouchthis1000
    @donttouchthis1000 10 років тому +1372

    Wait did DNA just fly out of his butt 2:24

    • @silkthyme
      @silkthyme 10 років тому +130

      He farted it out.

    • @angelofs4
      @angelofs4 9 років тому +24

      XD

    • @YaskSrivastava
      @YaskSrivastava 9 років тому +49

      That was really funny :D

    • @leVraiQuasar
      @leVraiQuasar 9 років тому +11

      perfumeorpoison that was stupid !... but of course i laugh... :-)

    • @EmanuelRodriguez
      @EmanuelRodriguez 9 років тому +33

      perfumeorpoison That's where DNA comes from. Deoxyribonucleic Assid

  • @logictd567
    @logictd567 7 років тому +319

    Nature, you scary.

    • @issamchriti1328
      @issamchriti1328 4 роки тому +7

      thats why we are destroying it and earth with it

    • @gertrofelixeiman1517
      @gertrofelixeiman1517 4 роки тому +1

      @@issamchriti1328 lmfao

    • @TinTin-is5eb
      @TinTin-is5eb 4 роки тому +2

      Issam chriti, your joking eight? We are 'destroying' it due to this generations naive ness and needs

    • @Superby25
      @Superby25 4 роки тому

      The E. coli creeps me

    • @REHANKHAN-en5zn
      @REHANKHAN-en5zn 4 роки тому

      Family guy

  • @0Tidus0989
    @0Tidus0989 9 років тому +25

    This video has one of the best animations\illustrations offered by TED-Ed imho. Great job! ^^

  • @Tutatsuta
    @Tutatsuta 2 роки тому +4

    I don’t know Why I haven’t discovered this channel Before… I have been captivated by these videos for almost half an hour and I’m lovin’ it!

  • @bubba6755
    @bubba6755 5 років тому +138

    1:51 me trying to show my useless talent

  • @GTron13
    @GTron13 3 роки тому +34

    2:22 is the equivalent of dropping loot in video games

  • @fakemadereal
    @fakemadereal 10 років тому +32

    3:43 Hey look! It's the Professor!

  • @pranjal87
    @pranjal87 10 років тому +5

    Please do a continuing lesson on the new methods which scientists are working on.

  • @takemeseriously9577
    @takemeseriously9577 8 років тому +349

    3:40 Samurai Jack? anyone?

    • @IllinoisTrafficAttorney
      @IllinoisTrafficAttorney 8 років тому +78

      +Ron TaylorAccosi Nah, Professor Utonium.

    • @Ritzy304
      @Ritzy304 8 років тому +6

      +Jason Wilkins same person

    • @corruptor55
      @corruptor55 8 років тому +18

      +Ron TaylorAccosi I think that was the professor from the powerpuff girls :3

    • @Pikminman1000
      @Pikminman1000 8 років тому +1

      I love that show

    • @Infreakingception
      @Infreakingception 8 років тому +1

      yep, definitely a reference

  • @purebaldness
    @purebaldness 10 років тому +299

    3:41 - professor utonium!

  • @ej_l2525
    @ej_l2525 5 років тому +1

    These videos are gold for visual and kinesthetic learner like me.

  • @monckeywrench4823
    @monckeywrench4823 5 років тому +3

    Thanks for sharing this,,More meaningful and beneficial videos like these please..Thank you Ted-Ed

  • @thebacteriawasbeatentodeath
    @thebacteriawasbeatentodeath 2 роки тому +14

    ok this is an amazing video with valuable information, great art, and amazing wording that makes the information easy to understand.
    that's still not going to change the fact that if the internet found this today, it would become a meme. hands down. it's hilarious and that adds to the video even more. the kids in my class even paid attention to it because of the funny animated bits and it made the video even more effective and enjoyable. love this lmao

  • @elizacardosoo
    @elizacardosoo 3 роки тому +1

    I really enjoyed the animation, thanks for the video!

  • @cesarfullculturaperuruizme979

    A huge thank you for all your content

  • @malafanai4026
    @malafanai4026 3 роки тому +36

    Once again Thank you Ted Ed for such an educational information 💪🏻

  • @rv7699
    @rv7699 8 років тому +4

    Really good and simple explanation =]

  • @Georgesbarsukov
    @Georgesbarsukov 9 років тому +46

    I liked the animation

  • @dannieros3
    @dannieros3 Рік тому

    This video was way more intense than I thought it would be

  • @7777stine
    @7777stine 10 років тому +261

    2:23 Well Then
    3:37 He made PowerPuff Girls, then I believe He can make non resistant Antibiotics

    • @huh9276
      @huh9276 5 років тому

      Stine Newton qw

  • @theplumscrub1627
    @theplumscrub1627 5 років тому +4

    My mom gave me homework to do about biology and bacteria. I had to watch some science videos and when i saw i had to watch ted-ed the studying suddenly became more fun! :)

  • @MuhdHaekal
    @MuhdHaekal 7 років тому

    haha this is phenomenal what an amazing cartoon features :) thanks guys!!!

  • @etiennepalos4319
    @etiennepalos4319 8 років тому +189

    3:42 Professor from Power Puff Girls

    • @Nookazz
      @Nookazz 8 років тому +5

      +etienne palos yes ! :D i only scrolled down to the comments to see if someone noticed it too :D

    • @adiboy010
      @adiboy010 8 років тому +4

      +etienne palos Yeah! Professor Utonium :D

    • @jasperdecastro5215
      @jasperdecastro5215 6 років тому

      Ha lol
      !!!!!!!!!!!!!!!!!!!

  • @kahyunpark3668
    @kahyunpark3668 8 років тому +4

    at first i thought that this kevin wu was our dear love kevjumba

  • @anniehyams4477
    @anniehyams4477 2 роки тому +4

    Thank you for the interesting video but I have had a Colon operation due to ear infections and bad bacteria in my body for the last 50 odd years and still on going on and off from antibiotics from time to time and as I am getting older in my pension years I can feel I am getting weaker thank you so much for sharing this video did not know any information about antibiotics until I could feel it and now your video thank you @ Ted-Ed 👍👍😀😀🌹🌹❤️❤️

  • @Jasonificatiation
    @Jasonificatiation 8 років тому

    great production/animation/narration/writing/directing/etc :)

  • @tahls.equi0232
    @tahls.equi0232 7 років тому +1

    Thank you for this video, I am doing a little big idea thing with my school

  • @rabukaxen9595
    @rabukaxen9595 2 роки тому +14

    3:26
    Nobody else could make me afraid of a bacteria's appearance.
    Thanks Ted-ed.

  • @TrueCorventus
    @TrueCorventus 10 років тому +79

    As a medical student, I approve of this video.

  • @sciencetrainee3583
    @sciencetrainee3583 4 роки тому

    This video is genius like! Enjoyed illustrations.

  • @machinismus
    @machinismus 9 місяців тому

    watched this in my genetics class today and I love the art style haha.

  • @Wildc4rd
    @Wildc4rd 10 років тому +19

    I couldn't help getting distracted by these animations..haha.

  • @kellykels4266
    @kellykels4266 7 років тому +5

    This is hilarious I found myself chuckling a couple times.

  • @ashikacharya
    @ashikacharya 2 роки тому

    Very information content. The animation was very funny and informative.

  • @MarcoCastilloVideos
    @MarcoCastilloVideos 9 років тому

    Awesome thanks for the captions

  • @hectortv8762
    @hectortv8762 7 років тому +36

    1:18 dammit the medicine just killed elvis

  • @FaceD0wnDagon
    @FaceD0wnDagon 8 років тому +19

    There's also the fact that sometimes, an antibiotic resistant gene sacrifices bacterial performance in order to become antibiotic resistant. For example, in the case of a gene which replaces a protein with a slightly less effiicient protein that the antibiotic nonetheless cannot bind to or combat.
    In these cases, the "superbugs" don't do very well outside a hospital environment (where their mutation is useful instead of a burden), and often don't exist outside their boundaries.

  • @marissahosein1273
    @marissahosein1273 7 років тому +2

    That make out session tho 😂
    But seriously this video was very helpful to me 👍🏽keep up the awesome work

  • @MichelRamosThe-Human
    @MichelRamosThe-Human 8 років тому

    What a great animation!

  • @louisasevier1034
    @louisasevier1034 2 роки тому +41

    I love this video! It's fun, interesting, and relevant. I would really like it if Ted ED did a video on the prophylactic use of antibiotics. I have issues with my immune system and get sick every other month with an upper respiratory infection. My doctors have been trying to figure out why for 8 years. But, for the past few years they've had me take an antibiotic three days a week and it has helped a bit with the severity of my infections. I think it could be an interesting topic for a video, plus I'm tired of having to explain it! 😂

  • @thebigenderqueen1586
    @thebigenderqueen1586 4 роки тому +56

    Narrator: blah blah blah deadly epidemic
    Me: hMm sOUndS fAmiLaR
    I would also like to know what a floating purple ball with a bow does for our body 😂😂😂

  • @carlcjjohnson6082
    @carlcjjohnson6082 Рік тому +1

    Im learning so much

  • @mohammedal-hammadi5085
    @mohammedal-hammadi5085 4 роки тому

    It's a great video, thank you so much

  • @ambientq7299
    @ambientq7299 10 років тому +45

    Very informative. I wonder how the state of our medicine will look like 10 years from now.

    • @Nobody-yx8og
      @Nobody-yx8og 2 роки тому +7

      3 years. If you still alive, you will be able to see it after waiting 3 more years.

    • @thebigounce391
      @thebigounce391 2 роки тому +3

      Well. Three more years to go, whaddya think so far?

    • @Kay-ok7qv
      @Kay-ok7qv 2 роки тому +1

      3 more years to go!

    • @asdawasda
      @asdawasda Рік тому +1

      two

    • @Vodka6329
      @Vodka6329 Рік тому +3

      just 2 years to go!

  • @ReaperFoxeS
    @ReaperFoxeS 7 років тому +5

    0:39 that one bacteria guy that he is even beneficial eating something its so funny :D

  • @noramnini3879
    @noramnini3879 8 років тому

    thank you this video really helped

  • @katiewaity3413
    @katiewaity3413 5 років тому

    the illustrations are very cool and pretty!!! love

  • @what-chu-mean7671
    @what-chu-mean7671 4 роки тому +6

    4:21 why is that called pork chop Bob 😂

  • @khangtran69
    @khangtran69 5 років тому +41

    1:27 : Thanos without glove
    1:29 : Thanos with glove

  • @draldosarymohammed
    @draldosarymohammed 9 років тому +2

    Thank you so much
    That's very helpful… we must stop prescribing antibiotic randomly to prevent misuse and therefore the resistance

  • @StaceyFoxx
    @StaceyFoxx Рік тому

    Such a good animation !

  • @Urb4n0Ninj4
    @Urb4n0Ninj4 9 років тому +40

    Is that The Professor from Powerpuff Girls at 3:38!?! We're saved!!!

  • @flargarbason1740
    @flargarbason1740 5 років тому +8

    Fun fact: the first and still widely used antibiotic, penicillin was created on accident when a scientist found a bunch of mold that killed his petri dishes of bacteria samples he was studying and then used that mold to develop the first antibiotic that we still use today.

  • @TranquilOblivion
    @TranquilOblivion 10 років тому

    Awesome animations!

  • @terelelli01
    @terelelli01 5 місяців тому +1

    that TED-Ed share such wonderful video increases our awareness and become us a lot more conscious against our environment.

  • @2ndsizta116
    @2ndsizta116 3 роки тому +14

    0:38 "although you have 10 times more bacterial cells inside you than your body has human cells-"
    green spiky bacteria: *shook *

    • @nidhiagrawal3354
      @nidhiagrawal3354 2 роки тому

      It's actually a bit like 1 to 1 instead of 10 to 1. It's ok to be smart made a video about it, debunking it: ua-cam.com/video/jijuG9tyoR0/v-deo.html

  • @mexshadowhope
    @mexshadowhope 10 років тому +16

    3:33 Bunsen and Beaker :D

  • @bryanchan5083
    @bryanchan5083 4 роки тому

    Thank you! I learn !!!

  • @hellokitti1987
    @hellokitti1987 9 років тому

    this was very helpful

  • @garfieldbudd6565
    @garfieldbudd6565 6 років тому +25

    When you evolve Drug Resistance 2 in Plague Inc.

  • @Rukiachan05
    @Rukiachan05 2 роки тому +3

    The animation was hilarious and cute in this video 😆 Thanks again for another interestingly informative lesson!

  • @baraaal_mousawi2367
    @baraaal_mousawi2367 Рік тому

    فيديو لطيف و معلومات حلوه عاشت الايادي ❤️😍

  • @369thegoose1
    @369thegoose1 4 роки тому +1

    Oh my God ..this was awesome....I had to listen to it 2x because I was laughing so much...hahha thank you!

  • @davidnorell
    @davidnorell 4 роки тому +5

    I am on the frontline of getting sick. There seems to be a ''fear'' by the medical practitioners to approach antibiotics with kid gloves. Instead of giving a very powerful level of antibiotics, giving smaller versions as a way to chip away at the infection. Unfortunately, by killing off the weaker forms of the infection, all they are doing is allowing the worse parts of the infection to thrive instead. Kind of like inoculating the infection to make it stronger versus the antibiotic.

  • @xxiconicxx0720
    @xxiconicxx0720 3 роки тому +7

    Who’s here from school?

  • @ghiathshaheen5742
    @ghiathshaheen5742 4 роки тому

    Shout out to the Animator , Great Work !

  • @nanalien2688
    @nanalien2688 8 років тому

    Cool. The animation was awesome

  • @HumeanPiano
    @HumeanPiano 7 років тому +269

    3:40 power puff girls reference

  • @bathingapes112
    @bathingapes112 7 років тому +7

    Also, the ending helped me understand why people are straying away from antibiotic injected meats. Very informational!

  • @CerratoFamily
    @CerratoFamily 2 роки тому +1

    TED ED is the best channel and this is the best video

  • @siddhantpareek1268
    @siddhantpareek1268 7 років тому

    thanks its very helpful

  • @DulceAdiccionOriginal
    @DulceAdiccionOriginal 7 років тому +12

    2:24 the best fart... I mean the best part of the video jaja, so funny.

  • @carolinnelemos9053
    @carolinnelemos9053 3 роки тому +4

    Healthcare professionals can’t take the risk of having their patients getting a deadly infection just because of non-resistant 🦠 . Also in a hospital setting there is no way to know or time find out if you are caring them or not.

  • @user-ct8xt2ml4i
    @user-ct8xt2ml4i 7 років тому +1

    thank you very very very much

  • @neon-nights
    @neon-nights 8 років тому

    Fun to watch :)

  • @MasterJongXG
    @MasterJongXG 10 років тому +10

    3:40
    Professor Utonium =D

  • @anonymouscapybara6306
    @anonymouscapybara6306 5 років тому +3

    my favourite bit is 2:19

  • @ramyashreea4841
    @ramyashreea4841 2 роки тому

    good information

  • @ascencioncoronamendoza3415
    @ascencioncoronamendoza3415 9 місяців тому

    I really Loved this video.

  • @HI-sk9kn
    @HI-sk9kn 10 років тому +7

    Is that professor Utonium? :)

  • @nasirkhan-cx6uo
    @nasirkhan-cx6uo 3 роки тому +3

    Are antibiotic producing isolates sensitive to the known antibiotic? If yes, what does the cell tell us about the isolates and how might they relate to their antibiotic?

  • @angelofs4
    @angelofs4 9 років тому

    Omg! Lol, that was awesome funny and cute animations xD.

  • @FubukiShiromiya
    @FubukiShiromiya 8 років тому +44

    Prescribing antibiotics trivially for humans isn't nearly as massive a problem in resistance as heavy use of antibiotics in factory farming to keep animals alive in cruel and unsanitary conditions.

    • @jormungarden5816
      @jormungarden5816 6 років тому +4

      Eric it actually is... specially when patients don't finish their antibiotics and "save them for later" when they start feeling better, this selects resistant strands of already pathogenic microorganism and reduce their overall sensitivity to said antibiotic, while the meat industry has a hand on this it doesn't play a huge part in the selection of pathogenic strands simply because the bacteria that infect those animals are largely different from the ones that infect us but we can certainly thank them for both bordetella and klebsiella strands with lowered sensitivity.

    • @SerenEnfys
      @SerenEnfys 2 роки тому

      @@jormungarden5816 how is the bacteria that affects non-human animals different to the bacteria that affects us human animals? We're not some superior immune species of the animalia kingdom? This comment aged well considering we're in a global pandemic that started because we exploit non-human animals 😅

    • @jormungarden5816
      @jormungarden5816 2 роки тому

      @@SerenEnfys it has aged really well if you know the difference between a virus and a bacteria, or the fact that viruses have an easier time making a jump between species than bacteria, or the fact that antibiotic misuse doesn't increase virus resistance to their medications unlike bacteria, and the difference between the bacteria that affect human and other animals has little to do with our immune system and more to do with the mechanism those bacteria use to survive, thrive and cause disease on their hosts, the amount of usable genetic information a bacteria has is limited and that's the reason they "specialize" for lack of a better term in a certain host, they have means to increase or change that genetic information on certain occasions, but it's the rarity of those occasions that make it harder for them to do a jump between species, that's not to say ingesting them won't make you feel sick but it won't cause an infection like it would on its usual host, and again there are multiple bacteria that can affect both human and animal hosts, staying on subject some of them being klebsiella, bordetella and mycobacterium bovis, that doesn't mean that the use of antibiotics on animals is the sole cause for resistant strands specially with people doing stuff like taking azithromycin for a sore throat.

  • @dylangarrett8133
    @dylangarrett8133 7 років тому +122

    So why does my doctor give me antibiotics every time I go in for anything?

    • @AnhTrieu90
      @AnhTrieu90 7 років тому +49

      He better has a very good explanation for that; otherwise, it's literally malpractice.

    • @dylangarrett8133
      @dylangarrett8133 7 років тому +11

      Anh Triệu it is quite common to hand out antibiotics "just in case" you don't have an infection.

    • @dylangarrett8133
      @dylangarrett8133 7 років тому +7

      Anh Triệu not to mention all the antibiotics in our animal meats, hand washes, and vaccines.

    • @kingdice9890
      @kingdice9890 7 років тому

      👍👈👆👊🙌🖖

    • @kenzofinucane4057
      @kenzofinucane4057 7 років тому +43

      causs hes a greedy moron that only cares about peddling the drugs he gets money to prescribe

  • @alexasromanu
    @alexasromanu 9 років тому +2

    I struggled last year with staphylococcus aureus for about three months.

  • @baileyryan488
    @baileyryan488 10 місяців тому

    This channel is better than going to school

  • @johnronald9767
    @johnronald9767 6 років тому +5

    1:03 sounded like someone walked into a desk

  • @theeclecticbanjo
    @theeclecticbanjo 6 років тому +6

    @ 1:20 - while human cells can be unharmed, microbes that are healthy for the human body can be affected by antibiotics, thus collateral damage, right?

  • @MostKnownUnKnown91
    @MostKnownUnKnown91 10 років тому

    Nice animations

  • @dr.monikabhuriya10
    @dr.monikabhuriya10 8 років тому

    Thank you so much medam.nice video.

  • @justastrawberrymonst
    @justastrawberrymonst 10 років тому +3

    3:39 -Professor Utonium!

  • @sammytrillo7724
    @sammytrillo7724 7 років тому +18

    Mutations aren't random, they respond directly to the environment. A farm pig doesn't randomly uncoil its tail and grow fur when it escapes and becomes feral, it's genetics respond to the environment via a subatomic observor function within RNA.

    • @gwiber282
      @gwiber282 5 років тому +4

      Mutations are random: whether a mutation becomes established in the population depends on environmental influences. Sometimes certain genes can be activated or deactivated through environmental factors, although I don't know offhand whether this is the cause of the changes you mentioned in individual domesticated animals like pigs when they escape and become feral. In any case, what you're talking about is different from genetic mutations.

  • @ilzegrina1424
    @ilzegrina1424 5 років тому

    This cartoon made me laugh! Lovely and educating.

  • @tagtaa9796
    @tagtaa9796 3 роки тому +1

    The part about Staphylococcus auereus is very true. I got it, it was bad used prescribed Erithromiccin.